Target list

Search results for query: Union of (#1, #2, #7, #8)

  • Score for genes in query #7 (Plasmodium falciparum genes with druggability index higher than 0.7): 40
  • Score for genes in query #2 (Plasmodium falciparum genes present in parasites and yeast but absent in animals): 20
  • Score for genes in query #8 (Plamodium falciparum genes with any essentiality ): 50
  • Score for genes in query #1 (Plasmodium falciparum enzymes with structure): 10

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

Retrieve:

1481 records found | Showing page 3 of 60 (records 51-75) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
P. falciparum   PF3D7_0810800   OG5_128803   hydroxymethyldihydropterin pyrophosphokinase-dihydropteroate synthase 80
P. falciparum   PF3D7_1022800   OG5_130276   4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 80
P. falciparum   PF3D7_1323000   OG5_130367   beta-hydroxyacyl-ACP dehydratase 80
P. falciparum   PF3D7_1327600   OG5_131883   nicotinamide/nicotinic acid mononucleotide adenylyltransferase 80
P. falciparum   PF3D7_1467300   OG5_130462   1-deoxy-D-xylulose 5-phosphate reductoisomerase 80
P. falciparum   PF3D7_0209300   OG5_130616   2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 80
P. falciparum   PF3D7_0211400   OG5_129509   beta-ketoacyl-ACP synthase III 80
P. falciparum   PF3D7_0219500   OG5_128305   pseudouridine synthase, putative 80
P. falciparum   PF3D7_0420200   OG5_130884   holo-[acyl-carrier-protein] synthase, putative 80
P. falciparum   PF3D7_0503100   OG5_130885   4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, putative 80
P. falciparum   PF3D7_0520500   OG5_128612   phosphomethylpyrimidine kinase, putative 80
P. falciparum   PF3D7_0623000   OG5_128304   chorismate synthase 80
P. falciparum   PF3D7_0922400   OG5_131264   para-aminobenzoic acid synthetase 80
P. falciparum   PF3D7_1350700   OG5_130478   N6-adenine-specific methylase, putative 70
P. falciparum   PF3D7_1365100   OG5_149624   mitochondrial ribosomal protein S17 precursor, putative 70
P. falciparum   PF3D7_1033400   OG5_127435   haloacid dehalogenase-like hydrolase 70
P. falciparum   PF3D7_1103400   OG5_132298   FeS cluster assembly protein SufD, putative 70
P. falciparum   PF3D7_1113900   OG5_138034   mitogen-activated protein kinase 2 70
P. falciparum   PF3D7_1413500   OG5_130065   FeS assembly ATPase SufC 70
P. falciparum   PF3D7_1469000   OG5_130791   translation initiation factor IF-1 70
P. falciparum   PF3D7_0104400   OG5_130373   4-hydroxy-3-methylbut-2-enyl diphosphate reductase 70
P. falciparum   PF3D7_0201900   OG5_132376   erythrocyte membrane protein 3 70
P. falciparum   PF3D7_0206100   OG5_127283   cysteine desulfuration protein SufE 70
P. falciparum   PF3D7_0503000   OG5_130709   50S ribosomal protein L28, apicoplast, putative 70
P. falciparum   PF3D7_0514100   OG5_127542   ATP-dependent DNA helicase UvrD 70

Showing page 3 (records 51-75) of 60