Target list

Search results for query: Union of (#1, #2, #7, #8)

  • Score for genes in query #7 (Plasmodium falciparum genes with druggability index higher than 0.7): 40
  • Score for genes in query #1 (Plasmodium falciparum enzymes with structure): 10
  • Score for genes in query #2 (Plasmodium falciparum genes present in parasites and yeast but absent in animals): 20
  • Score for genes in query #8 (Plamodium falciparum genes with any essentiality ): 50

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

Retrieve:

1481 records found | Showing page 2 of 60 (records 26-50) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
P. falciparum   PF3D7_0509800   OG5_127682   phosphatidylinositol 4-kinase 100
P. falciparum   PF3D7_0510500   OG5_127702   topoisomerase I 100
P. falciparum   PF3D7_0630300   OG5_127942   DNA polymerase epsilon catalytic subunit A, putative 100
P. falciparum   PF3D7_0920800   OG5_126887   inosine-5'-monophosphate dehydrogenase 100
P. falciparum   PF3D7_1206600   OG5_126694   DNA-directed RNA polymerase III subunit RPC2, putative 100
P. falciparum   PF3D7_1239500   OG5_128755   DNA gyrase subunit B 100
P. falciparum   PF3D7_1246900   OG5_126635   RAC-beta serine/threonine protein kinase 100
P. falciparum   PF3D7_1247500   OG5_127425   serine/threonine protein kinase, putative 100
P. falciparum   PF3D7_1356900   OG5_126712   protein kinase 5 90
P. falciparum   PF3D7_0820000   OG5_127568   Snf2-related CBP activator, putative 90
P. falciparum   PF3D7_0803700   OG5_127652   tubulin gamma chain 90
P. falciparum   PF3D7_1008700   OG5_126611   tubulin beta chain 90
P. falciparum   PF3D7_1108400   OG5_126901   casein kinase 2, alpha subunit 90
P. falciparum   PF3D7_1114700   OG5_128795   serine/threonine protein kinase, putative 90
P. falciparum   PF3D7_1119400   OG5_155603   ubiquitin-protein ligase, putative 90
P. falciparum   PF3D7_1148000   OG5_128190   serine/threonine protein kinase, putative 90
P. falciparum   PF3D7_1352100   OG5_126996   ABC transporter B family member 6, putative 90
P. falciparum   PF3D7_1426500   OG5_126574   ABC transporter G family member 2 90
P. falciparum   PF3D7_1447900   OG5_126733   multidrug resistance protein 2 90
P. falciparum   PF3D7_0302100   OG5_127107   serine/threonine protein kinase 90
P. falciparum   PF3D7_0417800   OG5_129183   cdc2-related protein kinase 1 90
P. falciparum   PF3D7_0422300   OG5_126605   alpha tubulin 2 90
P. falciparum   PF3D7_0523000   OG5_126596   multidrug resistance protein 1 90
P. falciparum   PF3D7_0934800   OG5_126748   cAMP-dependent protein kinase catalytic subunit 90
P. falciparum   PF3D7_0716600   OG5_128800   cysteine desulfurase 80

Showing page 2 (records 26-50) of 60