Target list

Search results for query: T. brucei targets - composite weighted query (DSR)

  • Score for genes in query #36 (T. brucei 3D structures): 50
  • Score for genes in query #34 (T. brucei published): 35
  • Score for genes in query #7 (Essential (in any organism)): 40
  • Score for genes in query #35 (T. brucei lethal (KO or KD)): 50
  • Score for genes in query #30 (Compound desirability (>0.3)): 35
  • Score for genes in query #27 (T. brucei <100kDa): 20
  • Score for genes in query #6 (T. brucei, NOT human): 25
  • Score for genes in query #33 (T. brucei no TM domains): 20
  • Score for genes in query #4 (T. brucei models): 30
  • Score for genes in query #29 (Druggability precedent (>0.6)): 35
  • Score for genes in query #5 (Present in all TriTryps): 25
  • Score for genes in query #2 (T. brucei enzymes): 100

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

Retrieve:

8361 records found | Showing page 333 of 335 (records 8301-8325) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
T. brucei   Tb927.6.2530   OG5_247819   hypothetical protein 20
T. brucei   Tb927.5.540   OG5_206672   hypothetical protein 20
T. brucei   Tb427tmp.02.0540   OG5_185163   hypothetical protein 20
T. brucei   Tb927.7.7310     No group hypothetical protein 20
T. brucei   Tb927.1.10     No group hypothetical protein 20
T. brucei   Tb927.10.3410   OG5_247869   hypothetical protein 20
T. brucei   Tb927.3.3700   OG5_206640   hypothetical protein 20
T. brucei   Tb927.7.6780   OG5_206695   hypothetical protein 20
T. brucei   Tb927.3.1640   OG5_206635   hypothetical protein 20
T. brucei   Tb927.1.1860   OG5_247280   Uncharacterized protein 20
T. brucei   Tb927.3.2800   OG5_185169   hypothetical protein 20
T. brucei   Tb927.10.9620   OG5_247390   NADH-ubiquinone oxidoreductase c 20
T. brucei   Tb427.10.13410     No group hypothetical protein 20
T. brucei   Tb927.10.2360   OG5_247867   hypothetical protein 20
T. brucei   Tb927.4.1010   OG5_247515   hypothetical protein 20
T. brucei   Tb927.5.1480   OG5_206666   hypothetical protein 20
T. brucei   Tb927.9.6830   OG5_133707   hypothetical protein 20
T. brucei   Tb927.7.6100   OG5_185212   hypothetical protein 20
T. brucei   Tb927.10.9550   OG5_247388   hypothetical protein 20
T. brucei   Tb927.7.3480   OG5_206683   hypothetical protein 20
T. brucei   Tb927.6.1150   OG5_247815   hypothetical protein 20
T. brucei   Tb927.5.1740   OG5_206667   hypothetical protein 20
T. brucei   Tb927.10.13420   OG5_247412   hypothetical protein 20
T. brucei   Tb927.3.1650   OG5_247799   hypothetical protein 20
T. brucei   Tb927.6.4730     No group hypothetical protein 20

Showing page 333 (records 8301-8325) of 335