Target list

Search results for query: T. brucei targets - composite weighted query (DSR)

  • Score for genes in query #29 (Druggability precedent (>0.6)): 35
  • Score for genes in query #4 (T. brucei models): 30
  • Score for genes in query #27 (T. brucei <100kDa): 20
  • Score for genes in query #2 (T. brucei enzymes): 100
  • Score for genes in query #34 (T. brucei published): 35
  • Score for genes in query #5 (Present in all TriTryps): 25
  • Score for genes in query #6 (T. brucei, NOT human): 25
  • Score for genes in query #30 (Compound desirability (>0.3)): 35
  • Score for genes in query #35 (T. brucei lethal (KO or KD)): 50
  • Score for genes in query #36 (T. brucei 3D structures): 50
  • Score for genes in query #7 (Essential (in any organism)): 40
  • Score for genes in query #33 (T. brucei no TM domains): 20

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

Retrieve:

8361 records found | Showing page 334 of 335 (records 8326-8350) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
T. brucei   Tb927.10.14290   OG5_247419   hypothetical protein 20
T. brucei   Tb927.6.1300   OG5_247816   hypothetical protein 20
T. brucei   Tb927.4.2810   OG5_247808   hypothetical protein 20
T. brucei   Tb927.9.2210   OG5_247669   hypothetical protein 20
T. brucei   Tb927.9.16950   OG5_247742   hypothetical protein 20
T. brucei   Tb927.7.3690   OG5_206685   hypothetical protein 20
T. brucei   Tb927.4.2090   OG5_206645   hypothetical protein 20
T. brucei   Tb927.8.1760   OG5_206699   hypothetical protein 20
T. brucei   Tb927.10.12610   OG5_206568   hypothetical protein 20
T. brucei   Tb927.9.8320   OG5_247717   hypothetical protein 20
T. brucei   Tb427tmp.28F8.200   OG5_206665   hypothetical protein 20
T. brucei   Tb927.9.790     No group hypothetical protein, conserved 20
T. brucei   Tb927.10.1010   OG5_247383   hypothetical protein 20
T. brucei   Tb927.10.3420   OG5_247435   NADH-ubiquinone oxidoreductase c, putative 20
T. brucei   Tb927.7.6650   OG5_162351   Colon cancer-associated protein Mic1-like, putative 20
T. brucei   Tb427.10.3190   OG5_247433   hypothetical protein 20
T. brucei   Tb927.3.3600   OG5_206639   hypothetical protein 20
T. brucei   Tb927.1.800     No group hypothetical transmembrane protein 20
T. brucei   Tb927.1.2310   OG5_247294   hypothetical protein 20
T. brucei   Tb927.4.4780   OG5_206655   hypothetical protein 20
T. brucei   Tb04.3I12.100     No group hypothetical protein 20
T. brucei   Tb927.11.820     No group hypothetical protein 20
T. brucei   Tb427.01.3610   OG5_206553   hypothetical protein 20
T. brucei   Tb427tmp.02.0050     No group hypothetical protein 20
T. brucei   Tb927.10.9630   OG5_206562   hypothetical protein 20

Showing page 334 (records 8326-8350) of 335