Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
491 records found | Showing page 3 of 20 (records 51-75) | Number of records to display | Find orthologs in
Organism | Name | Ortholog group | Product |
---|---|---|---|
T. brucei | Tb11.v5.0904 | OG5_127295 | glutaredoxin-like protein, putative |
T. brucei | Tb11.v5.0907 | OG5_146169 | variant surface glycoprotein (VSG, atypical), putative |
T. brucei | Tb11.v5.0911 | OG5_152007 | variant surface glycoprotein (VSG, atypical), putative |
T. brucei | Tb11.v5.0918 | OG5_134337 | variant surface glycoprotein (VSG, atypical), putative |
T. brucei | Tb11.v5.0923 | OG5_185246 | variant surface glycoprotein (VSG), putative |
T. brucei | Tb11.v5.0935 | OG5_247757 | variant surface glycoprotein (VSG, atypical), putative |
T. brucei | Tb11.v5.0952 | OG5_139889 | variant surface glycoprotein (VSG, atypical), putative |
T. brucei | Tb11.v5.0998 | OG5_126721 | methionine aminopeptidase, putative |
T. brucei | Tb11.v5.1015 | OG5_126617 | expression site-associated gene 4 (ESAG4) protein, putative |
T. brucei | Tb11.v5.1017 | OG5_135913 | variant surface glycoprotein (VSG), putative |
T. brucei | Tb11.v5.1060 | OG5_126668 | 40S ribosomal protein S18, putative |
T. brucei | Tb427.04.1100 | OG5_126766 | ribosomal protein L21E (60S), putative |
T. brucei | Tb427.04.4420 | No group | adenylyl cyclase, frameshift |
T. brucei | Tb427.05.4840 | No group | variant surface glycoprotein (VSG, atypical), putative |
T. brucei | Tb427.05.4980 | No group | variant surface glycoprotein, frameshift |
T. brucei | Tb427.05.5040 | No group | variant surface glycoprotein, point mutation |
T. brucei | Tb427.06.1030 | No group | cysteine peptidase, Clan CA, family C1, Cathepsin L-like |
T. brucei | Tb427.06.960 | No group | cysteine peptidase, Clan CA, family C1, Cathepsin L-like |
T. brucei | Tb427.07.1550 | No group | KRET2 |
T. brucei | Tb427.07.7470 | No group | receptor-type adenylate cyclase GRESAG 4, putative |
T. brucei | Tb427.08.5465 | OG5_133600 | 24 kDa calcimedin |
T. brucei | Tb427.08.7900 | No group | receptor-type adenylate cyclase GRESAG 4, putative |
T. brucei | Tb427.08.7910 | No group | receptor-type adenylate cyclase GRESAG 4, frameshift |
T. brucei | Tb427.08.7930 | No group | receptor-type adenylate cyclase GRESAG 4, putative |
T. brucei | Tb427.10.1090 | No group | 40S ribosomal protein S23, putative |