Target list

Search results for query: Wes VV TB Prioritized Targets: Structure, Enzyme, <600AA, essential, curated, not in human

  • Score for genes in query #61 (TB E coli essentials): 20
  • Score for genes in query #58 (TB w/ solved structures): 30
  • Score for genes in query #63 (TB not in human): 10
  • Score for genes in query #52 (TB enzymes (any EC #)): 35
  • Score for genes in query #62 (TB essential in any species): 10
  • Score for genes in query #60 (TB known essentials): 35
  • Score for genes in query #59 (TB with Modeled structures): 20
  • Score for genes in query #54 (TB < 600 AA): 25
  • Score for genes in query #48 (TB curated): 50

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

Retrieve:

2250 records found | Showing page 88 of 90 (records 2176-2200) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
M. tuberculosis   Rv3172c     No group Hypothetical protein 25
M. tuberculosis   Rv3185   OG5_128670   Probable transposase 25
M. tuberculosis   Rv3187   OG5_128670   Probable transposase 25
M. tuberculosis   Rv3212   OG5_237615   Conserved alanine valine rich protein 25
M. tuberculosis   Rv3218   OG5_128162   Conserved protein 25
M. tuberculosis   Rv3238c   OG5_133700   Probable conserved integral membrane protein 25
M. tuberculosis   Rv3243c     No group Unknown protein 25
M. tuberculosis   Rv3259   OG5_237608   Conserved hypothetical protein 25
M. tuberculosis   Rv3272   OG5_128463   Conserved hypothetical protein 25
M. tuberculosis   Rv3289c     No group Possible transmembrane protein 25
M. tuberculosis   Rv3326   OG5_128670   Probable transposase 25
M. tuberculosis   Rv3353c     No group Conserved hypothetical protein 25
M. tuberculosis   Rv3380c   OG5_128670   Probable transposase 25
M. tuberculosis   Rv3395c     No group Conserved hypothetical protein 25
M. tuberculosis   Rv3424c     No group Hypothetical protein 25
M. tuberculosis   Rv3437     No group Possible conserved transmembrane protein 25
M. tuberculosis   Rv3440c     No group Hypothetical protein 25
M. tuberculosis   Rv3453     No group Possible conserved transmembrane protein 25
M. tuberculosis   Rv3475   OG5_128670   Possible transposase for insertion element IS6110 [second part] 25
M. tuberculosis   Rv3489     No group Unknown protein 25
M. tuberculosis   Rv3527     No group Hypothetical protein 25
M. tuberculosis   Rv3528c     No group Unknown protein 25
M. tuberculosis   Rv3572     No group Unknown protein 25
M. tuberculosis   Rv3605c   OG5_237567   Probable conserved secreted protein 25
M. tuberculosis   Rv3612c     No group Conserved hypothetical protein 25

Showing page 88 (records 2176-2200) of 90