Target list

Search results for query: Wes VV TB Prioritized Targets: Structure, Enzyme, <600AA, essential, curated, not in human

  • Score for genes in query #58 (TB w/ solved structures): 30
  • Score for genes in query #63 (TB not in human): 10
  • Score for genes in query #60 (TB known essentials): 35
  • Score for genes in query #54 (TB < 600 AA): 25
  • Score for genes in query #52 (TB enzymes (any EC #)): 35
  • Score for genes in query #59 (TB with Modeled structures): 20
  • Score for genes in query #61 (TB E coli essentials): 20
  • Score for genes in query #62 (TB essential in any species): 10
  • Score for genes in query #48 (TB curated): 50

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

Retrieve:

2250 records found | Showing page 89 of 90 (records 2201-2225) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
M. tuberculosis   Rv3613c     No group Hypothetical protein 25
M. tuberculosis   Rv3632   OG5_237566   Possible conserved membrane protein 25
M. tuberculosis   Rv3656c     No group Conserved hypothetical protein 25
M. tuberculosis   Rv3657c     No group Possible conserved alanine rich membrane protein 25
M. tuberculosis   Rv3658c   OG5_140201   Probable conserved transmembrane protein 25
M. tuberculosis   Rv3675     No group Possible membrane protein 25
M. tuberculosis   Rv3686c     No group Conserved hypothetical protein 25
M. tuberculosis   Rv3695   OG5_204579   Possible conserved membrane protein 25
M. tuberculosis   Rv3718c   OG5_237789   Conserved protein 25
M. tuberculosis   Rv3753c   OG5_237812   Conserved protein 25
M. tuberculosis   Rv3766     No group Hypothetical protein 25
M. tuberculosis   Rv3789   OG5_216766   GTRA family protein 25
M. tuberculosis   Rv3819     No group Unknown protein 25
M. tuberculosis   Rv3831     No group Hypothetical protein 25
M. tuberculosis   Rv3839     No group Conserved hypothetical protein 25
M. tuberculosis   Rv3851     No group Possible membrane protein 25
M. tuberculosis   Rv3857c     No group Possible membrane protein 25
M. tuberculosis   Rv3881c     No group Secreted ESX-1 substrate protein B, EspB. Conserved alanine and glycine rich pro ... 25
M. tuberculosis   Rv3898c     No group Conserved hypothetical protein 25
M. tuberculosis   Rv1440   OG5_237595   Probable protein-export membrane protein (translocase subunit) SecG 25
M. tuberculosis   Rv1174c     No group Low molecular weight T-cell antigen TB8.4 25
M. tuberculosis   Rv0416   OG5_237575   Possible protein ThiS 25
M. tuberculosis   Rv3288c     No group Putative protein UsfY 25
M. tuberculosis   Rv0022c     No group Probable transcriptional regulatory protein WhiB-like WhiB5 25
M. tuberculosis   Rv3862c     No group Possible transcriptional regulatory protein WhiB-like WhiB6 25

Showing page 89 (records 2201-2225) of 90