Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0078 | 0.9039 | 0.979 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0067 | 0.724 | 0.801 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.004 | 0.2951 | 0.3265 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0044 | 0.3514 | 0.7399 |
Schistosoma mansoni | chromobox protein | 0.0078 | 0.9039 | 1 |
Echinococcus granulosus | tar DNA binding protein | 0.0071 | 0.7897 | 0.8737 |
Schistosoma mansoni | tar DNA-binding protein | 0.0071 | 0.7897 | 0.8737 |
Schistosoma mansoni | tar DNA-binding protein | 0.0071 | 0.7897 | 0.8737 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0025 | 0.0535 | 0.0592 |
Brugia malayi | RNA binding protein | 0.0071 | 0.7897 | 0.7673 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0071 | 0.7897 | 0.7673 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.3514 | 0.3678 |
Echinococcus multilocularis | tar DNA binding protein | 0.0071 | 0.7897 | 0.8737 |
Echinococcus multilocularis | chromobox protein 1 | 0.0078 | 0.9039 | 1 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.004 | 0.2951 | 0.3265 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0025 | 0.0535 | 0.0592 |
Schistosoma mansoni | hypothetical protein | 0.0023 | 0.0191 | 0.0211 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0044 | 0.3514 | 0.2714 |
Trichomonas vaginalis | chromobox protein, putative | 0.0078 | 0.9039 | 1 |
Schistosoma mansoni | bromodomain containing protein | 0.0071 | 0.7886 | 0.8724 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.4163 | 0.4395 |
Schistosoma mansoni | tar DNA-binding protein | 0.0071 | 0.7897 | 0.8737 |
Echinococcus granulosus | chromobox protein 1 | 0.0078 | 0.9039 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0071 | 0.7897 | 0.8737 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0071 | 0.7897 | 0.8527 |
Brugia malayi | Heterochromatin protein 1 | 0.0078 | 0.9039 | 0.8936 |
Echinococcus granulosus | chromobox protein 1 | 0.0078 | 0.9039 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.3391 | 0.3541 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.3818 | 0.4014 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0044 | 0.3514 | 0.2714 |
Brugia malayi | chromobox protein homolog 3 | 0.0044 | 0.3514 | 0.2824 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0047 | 0.405 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.0071 | 0.7897 | 0.8527 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0025 | 0.0535 | 0.0592 |
Schistosoma mansoni | chromobox protein | 0.0078 | 0.9039 | 1 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0067 | 0.724 | 0.801 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.1992 | 0.1993 |
Brugia malayi | TAR-binding protein | 0.0071 | 0.7897 | 0.7673 |
Loa Loa (eye worm) | TAR-binding protein | 0.0071 | 0.7897 | 0.8527 |
Trichomonas vaginalis | chromobox protein, putative | 0.0047 | 0.405 | 0.3419 |
Echinococcus multilocularis | chromobox protein 1 | 0.0078 | 0.9039 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.9228 | 1 |
Trichomonas vaginalis | chromobox protein, putative | 0.0078 | 0.9039 | 1 |
Trichomonas vaginalis | chromobox protein, putative | 0.0047 | 0.405 | 0.3419 |
Brugia malayi | Bromodomain containing protein | 0.0043 | 0.3378 | 0.2673 |
Schistosoma mansoni | tar DNA-binding protein | 0.0071 | 0.7897 | 0.8737 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.