Detailed information for compound 113374

Basic information

Technical information
  • TDR Targets ID: 113374
  • Name: 5,6-dichloro-1H-benzimidazole
  • MW: 187.026 | Formula: C7H4Cl2N2
  • H donors: 1 H acceptors: 1 LogP: 2.74 Rotable bonds: 0
    Rule of 5 violations (Lipinski): 1
  • SMILES: Clc1cc2[nH]cnc2cc1Cl
  • InChi: 1S/C7H4Cl2N2/c8-4-1-6-7(2-5(4)9)11-3-10-6/h1-3H,(H,10,11)
  • InChiKey: IPRDZAMUYMOJTA-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 6478-73-5
  • AIDS-129069
  • AIDS129069
  • NSC326397
  • 5R-0829
  • NSC 326397
  • ZINC00081227
  • Maybridge1_006289
  • NCIMech_000265
  • NCIOpen2_002664
  • NCI60_002831
  • 5,6-Dichloro-1H-benzoimidazole
  • MLS000767399
  • SMR000429730

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Trypanosoma brucei gambiense ATP-dependent phosphofructokinase,6-phospho-1-fructokinase No references
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Entamoeba histolytica phosphofructokinase, putative Get druggable targets OG5_126758 All targets in OG5_126758
Trypanosoma brucei gambiense ATP-dependent phosphofructokinase,6-phospho-1-fructokinase Get druggable targets OG5_126758 All targets in OG5_126758
Leishmania braziliensis ATP-dependent phosphofructokinase Get druggable targets OG5_126758 All targets in OG5_126758
Candida albicans phosphofructokinase alpha subunit that can functionally substitute for S. cerevisiae PFK1 (YGR240C) Get druggable targets OG5_126758 All targets in OG5_126758
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) Get druggable targets OG5_126758 All targets in OG5_126758
Entamoeba histolytica phosphofructokinase, putative Get druggable targets OG5_126758 All targets in OG5_126758
Loa Loa (eye worm) phosphofructokinase Get druggable targets OG5_126758 All targets in OG5_126758
Trichomonas vaginalis phosphofructokinase, putative Get druggable targets OG5_126758 All targets in OG5_126758
Trichomonas vaginalis phosphofructokinase, putative Get druggable targets OG5_126758 All targets in OG5_126758
Candida albicans phosphofructokinase beta-subunit that can functionally substitute for S. cerevisiae PFK2 (YMR205C) Get druggable targets OG5_126758 All targets in OG5_126758
Candida albicans hypothetical protein Get druggable targets OG5_126758 All targets in OG5_126758
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase Get druggable targets OG5_126758 All targets in OG5_126758
Brugia malayi 6-phosphofructokinase Get druggable targets OG5_126758 All targets in OG5_126758
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal Get druggable targets OG5_126758 All targets in OG5_126758
Brugia malayi phosphofructokinase Get druggable targets OG5_126758 All targets in OG5_126758
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal Get druggable targets OG5_126758 All targets in OG5_126758
Candida albicans phosphofructokinase beta-subunit that can functionally substitute for S. cerevisiae PFK2 (YMR205C) Get druggable targets OG5_126758 All targets in OG5_126758
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) Get druggable targets OG5_126758 All targets in OG5_126758
Schistosoma japonicum ko:K00850 6-phosphofructokinase [EC2.7.1.11], putative Get druggable targets OG5_126758 All targets in OG5_126758
Schistosoma mansoni 6-phosphofructokinase Get druggable targets OG5_126758 All targets in OG5_126758
Candida albicans phosphofructokinase alpha subunit that can functionally substitute for S. cerevisiae PFK1 (YGR240C) Get druggable targets OG5_126758 All targets in OG5_126758
Leishmania infantum ATP-dependent phosphofructokinase Get druggable targets OG5_126758 All targets in OG5_126758
Brugia malayi 6-phosphofructokinase Get druggable targets OG5_126758 All targets in OG5_126758
Entamoeba histolytica phosphofructokinase, putative Get druggable targets OG5_126758 All targets in OG5_126758
Loa Loa (eye worm) 6-phosphofructokinase Get druggable targets OG5_126758 All targets in OG5_126758
Echinococcus multilocularis 6 phosphofructokinase Get druggable targets OG5_126758 All targets in OG5_126758
Echinococcus granulosus 6 phosphofructokinase Get druggable targets OG5_126758 All targets in OG5_126758
Leishmania mexicana 6-phospho-1-fructokinase, putative Get druggable targets OG5_126758 All targets in OG5_126758
Trypanosoma congolense ATP-dependent 6-phosphofructokinase, glycosomal Get druggable targets OG5_126758 All targets in OG5_126758
Trichomonas vaginalis phosphofructokinase, putative Get druggable targets OG5_126758 All targets in OG5_126758
Trichomonas vaginalis phosphofructokinase, putative Get druggable targets OG5_126758 All targets in OG5_126758
Leishmania donovani ATP-dependent 6-phosphofructokinase, glycosomal Get druggable targets OG5_126758 All targets in OG5_126758
Leishmania major ATP-dependent phosphofructokinase Get druggable targets OG5_126758 All targets in OG5_126758
Mycobacterium ulcerans 6-phosphofructokinase Get druggable targets OG5_126758 All targets in OG5_126758
Schistosoma mansoni 6-phosphofructokinase Get druggable targets OG5_126758 All targets in OG5_126758
Loa Loa (eye worm) 6-phosphofructokinase Get druggable targets OG5_126758 All targets in OG5_126758
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) 6-phosphofructokinase 0.0131 0.1931 0.2769
Entamoeba histolytica hypothetical protein 0.0155 0.2408 1
Trichomonas vaginalis heat shock protein, putative 0.0043 0.0175 0.0736
Giardia lamblia Heat shock protein HSP 90-alpha 0.0043 0.0175 0.4954
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0068 0.0684 0.0518
Brugia malayi MH2 domain containing protein 0.0386 0.6974 1
Plasmodium vivax heat shock protein 86, putative 0.005 0.0317 0.0931
Echinococcus multilocularis isocitrate dehydrogenase 0.0068 0.0684 0.0518
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0068 0.0684 0.2898
Plasmodium falciparum ataxin-2 like protein, putative 0.0109 0.1488 0.4802
Brugia malayi hypothetical protein 0.0109 0.1488 0.2133
Brugia malayi hypothetical protein 0.0155 0.2408 0.3453
Leishmania major heat shock protein 83-1 0.005 0.0317 0.0361
Loa Loa (eye worm) isocitrate dehydrogenase 0.0068 0.0684 0.0981
Trypanosoma cruzi heat shock protein 85, putative 0.005 0.0317 0.0809
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0068 0.0684 0.2144
Schistosoma mansoni tar DNA-binding protein 0.0139 0.2083 0.2083
Leishmania major heat shock protein 83-1 0.005 0.0317 0.0361
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0131 0.1931 1
Trypanosoma cruzi heat shock protein 90, putative 0.005 0.0317 0.0809
Echinococcus multilocularis heat shock protein 90 0.005 0.0317 0.0145
Brugia malayi Isocitrate dehydrogenase 0.0068 0.0684 0.0981
Brugia malayi phosphofructokinase 0.0131 0.1931 0.2769
Schistosoma mansoni 6-phosphofructokinase 0.0131 0.1931 0.1931
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0068 0.0684 0.0518
Loa Loa (eye worm) endoplasmin 0.005 0.0317 0.0454
Schistosoma mansoni hypothetical protein 0.0155 0.2408 0.2408
Loa Loa (eye worm) hypothetical protein 0.0049 0.0308 0.0442
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0131 0.1931 1
Leishmania major ATP-dependent phosphofructokinase 0.0131 0.1931 1
Schistosoma mansoni 6-phosphofructokinase 0.0131 0.1931 0.1931
Trichomonas vaginalis phosphofructokinase, putative 0.0131 0.1931 1
Toxoplasma gondii Hsp90 domain-containing protein 0.0188 0.306 1
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0049 0.03 0.0127
Echinococcus granulosus heat shock protein 90 0.005 0.0317 0.0145
Schistosoma mansoni endoplasmin 0.005 0.0317 0.0317
Leishmania major heat shock protein 83-1 0.005 0.0317 0.0361
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0068 0.0684 0.0518
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0035 0.0035 0.5
Leishmania major heat shock protein 83-1 0.005 0.0317 0.0361
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0068 0.0684 0.0518
Schistosoma mansoni tar DNA-binding protein 0.0139 0.2083 0.2083
Loa Loa (eye worm) TAR-binding protein 0.0139 0.2083 0.2987
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0068 0.0684 0.2898
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0155 0.2408 0.2273
Entamoeba histolytica hypothetical protein 0.0155 0.2408 1
Schistosoma mansoni hypothetical protein 0.0539 1 1
Plasmodium falciparum endoplasmin, putative 0.0036 0.0047 0.0039
Trichomonas vaginalis phosphofructokinase, putative 0.0131 0.1931 1
Trichomonas vaginalis heat shock protein, putative 0.0036 0.0047 0.0063
Toxoplasma gondii heat shock protein 90, putative 0.005 0.0317 0.0931
Entamoeba histolytica phosphofructokinase, putative 0.0131 0.1931 0.7989
Leishmania major heat shock protein 83-1 0.005 0.0317 0.0361
Echinococcus multilocularis 6 phosphofructokinase 0.0131 0.1931 0.1787
Leishmania major heat shock protein 83-1 0.005 0.0317 0.0361
Toxoplasma gondii LsmAD domain-containing protein 0.0109 0.1488 0.4802
Brugia malayi RNA recognition motif domain containing protein 0.0139 0.2083 0.2987
Schistosoma mansoni tar DNA-binding protein 0.0139 0.2083 0.2083
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0068 0.0684 0.2273
Toxoplasma gondii isocitrate dehydrogenase 0.0068 0.0684 0.2144
Leishmania major hypothetical protein, conserved 0.0109 0.1488 0.7353
Trypanosoma cruzi heat shock protein 85, putative 0.005 0.0317 0.0809
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0068 0.0684 0.2273
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0047 0.0257 0.5
Schistosoma mansoni tar DNA-binding protein 0.0139 0.2083 0.2083
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0035 0.0035 0.5
Treponema pallidum heat shock protein 90 0.0047 0.0257 0.1166
Echinococcus granulosus 6 phosphofructokinase 0.0131 0.1931 0.1787
Echinococcus multilocularis heat shock protein 0.005 0.0317 0.0145
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0131 0.1931 1
Schistosoma mansoni hypothetical protein 0.0539 1 1
Trichomonas vaginalis endoplasmin, putative 0.0036 0.0047 0.0063
Brugia malayi TAR-binding protein 0.0139 0.2083 0.2987
Leishmania major heat shock protein 83-1 0.005 0.0317 0.0361
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0131 0.1931 1
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0068 0.0684 0.2552
Trichomonas vaginalis heat shock protein, putative 0.0047 0.0257 0.1166
Entamoeba histolytica phosphofructokinase, putative 0.0131 0.1931 0.7989
Leishmania major heat shock protein 83-1 0.005 0.0317 0.0361
Brugia malayi 6-phosphofructokinase 0.0131 0.1931 0.2769
Toxoplasma gondii isocitrate dehydrogenase 0.0068 0.0684 0.2144
Brugia malayi RNA binding protein 0.0139 0.2083 0.2987
Echinococcus granulosus endoplasmin 0.0047 0.0257 0.0083
Entamoeba histolytica hypothetical protein 0.0155 0.2408 1
Brugia malayi isocitrate dehydrogenase 0.0068 0.0684 0.0981
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0068 0.0684 0.2552
Mycobacterium ulcerans 6-phosphofructokinase 0.0131 0.1931 1
Leishmania major heat shock protein 83-1 0.005 0.0317 0.0361
Trichomonas vaginalis phosphofructokinase, putative 0.0131 0.1931 1
Schistosoma mansoni heat shock protein 0.005 0.0317 0.0317
Loa Loa (eye worm) RNA binding protein 0.0139 0.2083 0.2987
Schistosoma mansoni tar DNA-binding protein 0.0139 0.2083 0.2083
Entamoeba histolytica heat shock protein 90, putative 0.005 0.0317 0.1186
Entamoeba histolytica phosphofructokinase, putative 0.0131 0.1931 0.7989
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.0308 0.0442
Schistosoma mansoni heat shock protein 0.005 0.0317 0.0317
Trypanosoma cruzi PAB1-binding protein , putative 0.0109 0.1488 0.7476
Giardia lamblia Grp94/Hsp90 0.0047 0.0257 0.7854
Trypanosoma cruzi heat shock protein 85, putative 0.005 0.0317 0.0809
Entamoeba histolytica heat shock protein 90, putative 0.005 0.0317 0.1186
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.0308 0.0442
Plasmodium vivax ataxin-2 like protein, putative 0.0109 0.1488 0.4802
Schistosoma mansoni endoplasmin 0.005 0.0317 0.0317
Plasmodium vivax endoplasmin, putative 0.005 0.0317 0.0931
Loa Loa (eye worm) hypothetical protein 0.0109 0.1488 0.2133
Brugia malayi heat shock protein 90 0.005 0.0317 0.0454
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0049 0.03 0.0127
Echinococcus multilocularis endoplasmin 0.0047 0.0257 0.0083
Echinococcus multilocularis tar DNA binding protein 0.0139 0.2083 0.1942
Leishmania major heat shock protein 83-1 0.005 0.0317 0.0361
Trichomonas vaginalis heat shock protein, putative 0.0047 0.0257 0.1166
Echinococcus multilocularis geminin 0.0539 1 1
Trypanosoma brucei PAB1-binding protein , putative 0.0109 0.1488 0.7253
Leishmania major heat shock protein 83-1 0.005 0.0317 0.0361
Loa Loa (eye worm) transcription factor SMAD2 0.0386 0.6974 1
Loa Loa (eye worm) 6-phosphofructokinase 0.0131 0.1931 0.2769
Trichomonas vaginalis phosphofructokinase, putative 0.0131 0.1931 1
Loa Loa (eye worm) MH2 domain-containing protein 0.0386 0.6974 1
Toxoplasma gondii heat shock protein HSP90 0.005 0.0317 0.0931
Leishmania major heat shock protein 83-1 0.005 0.0317 0.0361
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0068 0.0684 0.2144
Trypanosoma cruzi Heat shock protein 83, putative 0.005 0.0317 0.0809
Plasmodium falciparum heat shock protein 90, putative 0.0188 0.306 1
Giardia lamblia Heat shock protein HSP 90-alpha 0.005 0.0317 1
Trichomonas vaginalis heat shock protein, putative 0.005 0.0317 0.1485
Leishmania major heat shock protein 83-1 0.005 0.0317 0.0361
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0068 0.0684 0.0684
Loa Loa (eye worm) heat shock protein 90 0.005 0.0317 0.0454
Brugia malayi Endoplasmin precursor 0.005 0.0317 0.0454
Leishmania major heat shock protein 83-1 0.005 0.0317 0.0361
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.0308 0.0442
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0068 0.0684 0.0518
Plasmodium falciparum heat shock protein 90 0.005 0.0317 0.0931
Schistosoma mansoni transcription factor LCR-F1 0.0155 0.2408 0.2408
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0139 0.2083 0.2987
Schistosoma mansoni hypothetical protein 0.0049 0.03 0.03
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0131 0.1931 1
Leishmania major heat shock protein 83-1 0.005 0.0317 0.0361
Leishmania major heat shock protein 83-1 0.005 0.0317 0.0361
Echinococcus granulosus tar DNA binding protein 0.0139 0.2083 0.1942
Plasmodium vivax heat shock protein, putative 0.0188 0.306 1
Plasmodium falciparum ataxin-2 like protein, putative 0.0109 0.1488 0.4802
Brugia malayi 6-phosphofructokinase 0.0131 0.1931 0.2769
Leishmania major heat shock protein 83-1 0.005 0.0317 0.0361
Entamoeba histolytica hypothetical protein 0.0155 0.2408 1
Brugia malayi hypothetical protein 0.007 0.0724 0.1039
Trypanosoma cruzi PAB1-binding protein , putative 0.0109 0.1488 0.7476
Loa Loa (eye worm) phosphofructokinase 0.0131 0.1931 0.2769
Echinococcus granulosus heat shock protein 0.005 0.0317 0.0145
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0155 0.2408 0.2273

Activities

Activity type Activity value Assay description Source Reference
GI50 (functional) -4.317 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.252 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HOP-92 Non-Small Cell Lung cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MALME-3M Melanoma cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) = 66 uM Cytotoxicity against human HCT116 cells after 48 hrs by MTT assay ChEMBL. 22225635
GI50 (functional) = 73 uM Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay ChEMBL. 22225635
IC50 (functional) = -7.02 Antiamoebic activity against Entamoeba histolytica ChEMBL. 17074492
IC50 (ADMET) = 4.09 Inhibitory potency to aminopyrine N-demethylase activity (P450) in hepatic microsomes from phenobarbitone-induced rats. ChEMBL. 7120277
IC50 (functional) = 0.096 uM The compound was tested in vitro against the protozoa Entamoeba histolytica, for the inhibition of tubulin polymerization in rat brain ChEMBL. 12127542
IC50 (functional) = 0.096 uM The compound was tested in vitro against the protozoa Entamoeba histolytica, for the inhibition of tubulin polymerization in rat brain ChEMBL. 12127542
IC50 (functional) = 0.358 uM The compound was tested in vitro against the protozoa Giardia lamblia, for the inhibition of tubulin polymerization in rat brain ChEMBL. 12127542
Log IC50 (functional) = 7.02 Antiamoebic activity against Entamoeba histolytica ChEMBL. 17074492
logP (ADMET) = 3.17 Partition coefficient (logP) ChEMBL. 7120277
pI50 (ADMET) = 4.09 Inhibitory potency to aminopyrine N-demethylase activity (P450) in hepatic microsomes from phenobarbitone-induced rats. ChEMBL. 7120277
Potency (functional) 19.0115 uM PUBCHEM_BIOASSAY: qHTS Assay to Find Inhibitors of T. brucei phosphofructokinase. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488768, AID492961] ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference
Viability (functional) = 18 % Percentage viability reduction of Trichinella spiralis muscle larvae after 3 days of incubation ChEMBL. 12127542

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Entamoeba histolytica ChEMBL23 12127542

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

3 literature references were collected for this gene.

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