Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium ulcerans | transglutaminase family protein | 0.0107 | 0.291 | 0.5 |
Echinococcus granulosus | suppression of tumorigenicity 18 protein | 0.0053 | 0.0752 | 0.1254 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0095 | 0.2417 | 0.7953 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0752 | 0.311 |
Giardia lamblia | Transglutaminase/protease, putative | 0.0107 | 0.291 | 1 |
Leishmania major | protein kinase, putative,polo-like protein kinase, putative | 0.0095 | 0.2417 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0095 | 0.2417 | 0.7953 |
Giardia lamblia | Hypothetical protein | 0.0107 | 0.291 | 1 |
Schistosoma mansoni | myelin transcription factor 1 myt1 | 0.0053 | 0.0752 | 0.0273 |
Entamoeba histolytica | serine/threonine protein kinase, putative | 0.0095 | 0.2417 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0285 | 0.9995 | 1 |
Echinococcus granulosus | serine:threonine protein kinase PLK1 | 0.0095 | 0.2417 | 0.4032 |
Plasmodium falciparum | FAD-linked sulfhydryl oxidase ERV1, putative | 0.0035 | 0 | 0.5 |
Plasmodium vivax | FAD-linked sulfhydryl oxidase ERV1, putative | 0.0035 | 0 | 0.5 |
Echinococcus multilocularis | suppression of tumorigenicity 18 protein | 0.0053 | 0.0752 | 0.1254 |
Brugia malayi | Thioredoxin family protein | 0.0107 | 0.291 | 1 |
Echinococcus multilocularis | serine:threonine protein kinase PLK1 | 0.0095 | 0.2417 | 0.4032 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0095 | 0.2417 | 0.7953 |
Loa Loa (eye worm) | MBCTL1 | 0.0053 | 0.0752 | 0.311 |
Trypanosoma brucei | polo-like protein kinase | 0.0095 | 0.2417 | 1 |
Echinococcus granulosus | endonuclease exonuclease phosphatase | 0.0185 | 0.5994 | 1 |
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.0095 | 0.2417 | 1 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0095 | 0.2417 | 1 |
Loa Loa (eye worm) | mbt repeat family protein | 0.0047 | 0.0493 | 0.2039 |
Mycobacterium leprae | Conserved hypothetical protein | 0.0107 | 0.291 | 0.5 |
Echinococcus multilocularis | Transglutaminase | 0.0107 | 0.291 | 0.4855 |
Brugia malayi | mbt repeat family protein | 0.0047 | 0.0493 | 0.1693 |
Schistosoma mansoni | hypothetical protein | 0.0107 | 0.291 | 0.2544 |
Echinococcus multilocularis | endonuclease exonuclease phosphatase | 0.0185 | 0.5994 | 1 |
Echinococcus multilocularis | polycomb protein SCMH1 | 0.0047 | 0.0493 | 0.0822 |
Mycobacterium ulcerans | putative transglutaminase-like protein | 0.0107 | 0.291 | 0.5 |
Trichomonas vaginalis | peptide N-glycanase, putative | 0.0107 | 0.291 | 1 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0107 | 0.291 | 0.5 |
Toxoplasma gondii | Erv1 / Alr family protein | 0.0035 | 0 | 0.5 |
Echinococcus granulosus | histone acetyltransferase MYST2 | 0.0053 | 0.0752 | 0.1254 |
Onchocerca volvulus | Serine\/threonine kinase homolog | 0.0095 | 0.2417 | 0.2024 |
Mycobacterium tuberculosis | Conserved protein | 0.0107 | 0.291 | 0.5 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0095 | 0.2417 | 0.7953 |
Mycobacterium leprae | Conserved hypothetical protein | 0.0107 | 0.291 | 0.5 |
Brugia malayi | serine/threonine-protein kinase plk-2 | 0.0095 | 0.2417 | 0.8305 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0107 | 0.291 | 0.5 |
Echinococcus multilocularis | SAM and MBT domain containing protein | 0.0047 | 0.0493 | 0.0822 |
Echinococcus granulosus | polycomb protein SCMH1 | 0.0047 | 0.0493 | 0.0822 |
Mycobacterium tuberculosis | Hypothetical protein | 0.0107 | 0.291 | 0.5 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0095 | 0.2417 | 0.7953 |
Mycobacterium ulcerans | hypothetical protein | 0.0107 | 0.291 | 0.5 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0095 | 0.2417 | 0.2025 |
Brugia malayi | mbt repeat family protein | 0.0047 | 0.0493 | 0.1693 |
Schistosoma mansoni | kinase | 0.0048 | 0.055 | 0.0061 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0095 | 0.2417 | 1 |
Toxoplasma gondii | Erv1 / Alr family protein | 0.0035 | 0 | 0.5 |
Brugia malayi | C2-HC type zinc finger protein C.e-MyT1 | 0.0053 | 0.0752 | 0.2583 |
Mycobacterium ulcerans | hypothetical protein | 0.0107 | 0.291 | 0.5 |
Echinococcus granulosus | SAM and MBT domain containing protein | 0.0047 | 0.0493 | 0.0822 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0095 | 0.2417 | 0.7953 |
Echinococcus granulosus | Transglutaminase | 0.0107 | 0.291 | 0.4855 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0095 | 0.2417 | 0.7953 |
Echinococcus multilocularis | histone acetyltransferase MYST2 | 0.0053 | 0.0752 | 0.1254 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0493 | 0.2039 |
Mycobacterium tuberculosis | Long conserved protein | 0.0107 | 0.291 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.