TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 442.553 | Formula: C27H30N4O2
H donors: 0 H acceptors: 2 LogP: 5.47 Rotable bonds: 9
Rule of 5 violations (Lipinski): 1
SMILES: CCc1nc2n(c1N(Cc1ccc(cc1)OC)C)cc(cc2)C(=O)N(Cc1ccccc1)C
InChi: 1S/C27H30N4O2/c1-5-24-26(29(2)17-21-11-14-23(33-4)15-12-21)31-19-22(13-16-25(31)28-24)27(32)30(3)18-20-9-7-6-8-10-20/h6-16,19H,5,17-18H2,1-4H3
InChiKey: NQRKCJPMMMGWGL-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species	Target name	Source	Bibliographic reference
Homo sapiens	SMAD family member 2	Starlite/ChEMBL	No references
Homo sapiens	isocitrate dehydrogenase 1 (NADP+), soluble	Starlite/ChEMBL	No references

Predicted pathogen targets for this compound

By orthology

Species	Potential target	Known druggable target/s	Ortholog Group
Candida albicans	cytosolic NADP-specific isocitrate dehydrogenase.	Get druggable targets OG5_127057	All targets in OG5_127057
Brugia malayi	MH2 domain containing protein	Get druggable targets OG5_131716	All targets in OG5_131716
Brugia malayi	Isocitrate dehydrogenase	Get druggable targets OG5_127057	All targets in OG5_127057
Candida albicans	Mitochondrial NADP-specific isocitrate dehydrogenase	Get druggable targets OG5_127057	All targets in OG5_127057
Leishmania braziliensis	isocitrate dehydrogenase [NADP], mitochondrial precursor, putative	Get druggable targets OG5_127057	All targets in OG5_127057
Plasmodium knowlesi	isocitrate dehydrogenase [NADP], mitochondrial, putative	Get druggable targets OG5_127057	All targets in OG5_127057
Trypanosoma brucei gambiense	isocitrate dehydrogenase [NADP], mitochondrial precursor, putative	Get druggable targets OG5_127057	All targets in OG5_127057
Echinococcus multilocularis	NADP dependent isocitrate dehydrogenase	Get druggable targets OG5_127057	All targets in OG5_127057
Echinococcus multilocularis	NADP dependent isocitrate dehydrogenase	Get druggable targets OG5_127057	All targets in OG5_127057
Candida albicans	C terminus of cytosolic NADP-specific isocitrate dehydrogenase.	Get druggable targets OG5_127057	All targets in OG5_127057
Echinococcus multilocularis	NADP dependent isocitrate dehydrogenase	Get druggable targets OG5_127057	All targets in OG5_127057
Loa Loa (eye worm)	transcription factor SMAD2	Get druggable targets OG5_131716	All targets in OG5_131716
Toxoplasma gondii	isocitrate dehydrogenase	Get druggable targets OG5_127057	All targets in OG5_127057
Leishmania major	isocitrate dehydrogenase [NADP], mitochondrial precursor, putative	Get druggable targets OG5_127057	All targets in OG5_127057
Toxoplasma gondii	isocitrate dehydrogenase	Get druggable targets OG5_127057	All targets in OG5_127057
Trypanosoma cruzi	isocitrate dehydrogenase, putative	Get druggable targets OG5_127057	All targets in OG5_127057
Candida albicans	N terminus of cytosolic NADP-specific isocitrate dehydrogenase.	Get druggable targets OG5_127057	All targets in OG5_127057
Trypanosoma brucei	isocitrate dehydrogenase, putative	Get druggable targets OG5_127057	All targets in OG5_127057
Brugia malayi	isocitrate dehydrogenase	Get druggable targets OG5_127057	All targets in OG5_127057
Mycobacterium tuberculosis	Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP)	Get druggable targets OG5_127057	All targets in OG5_127057
Theileria parva	isocitrate dehydrogenase (NADP+), putative	Get druggable targets OG5_127057	All targets in OG5_127057
Trypanosoma congolense	isocitrate dehydrogenase, putative	Get druggable targets OG5_127057	All targets in OG5_127057
Trypanosoma cruzi	isocitrate dehydrogenase [NADP], mitochondrial precursor, putative	Get druggable targets OG5_127057	All targets in OG5_127057
Loa Loa (eye worm)	MH2 domain-containing protein	Get druggable targets OG5_131716	All targets in OG5_131716
Plasmodium berghei	isocitrate dehydrogenase [NADP], mitochondrial, putative	Get druggable targets OG5_127057	All targets in OG5_127057
Loa Loa (eye worm)	isocitrate dehydrogenase	Get druggable targets OG5_127057	All targets in OG5_127057
Plasmodium yoelii	isocitrate dehydrogenase, NADP-dependent	Get druggable targets OG5_127057	All targets in OG5_127057
Trypanosoma brucei	isocitrate dehydrogenase [NADP], mitochondrial precursor, putative	Get druggable targets OG5_127057	All targets in OG5_127057
Babesia bovis	isocitrate dehydrogenase, NADP-dependent family protein	Get druggable targets OG5_127057	All targets in OG5_127057
Plasmodium vivax	isocitrate dehydrogenase [NADP], mitochondrial, putative	Get druggable targets OG5_127057	All targets in OG5_127057
Leishmania mexicana	isocitrate dehydrogenase [NADP], mitochondrial precursor, putative	Get druggable targets OG5_127057	All targets in OG5_127057
Trypanosoma brucei gambiense	isocitrate dehydrogenase, putative	Get druggable targets OG5_127057	All targets in OG5_127057
Leishmania infantum	isocitrate dehydrogenase [NADP], mitochondrial precursor, putative	Get druggable targets OG5_127057	All targets in OG5_127057
Plasmodium falciparum	isocitrate dehydrogenase [NADP], mitochondrial	Get druggable targets OG5_127057	All targets in OG5_127057
Echinococcus granulosus	NADP dependent isocitrate dehydrogenase	Get druggable targets OG5_127057	All targets in OG5_127057
Trypanosoma congolense	isocitrate dehydrogenase, putative	Get druggable targets OG5_127057	All targets in OG5_127057
Echinococcus multilocularis	isocitrate dehydrogenase 2 (NADP+)	Get druggable targets OG5_127057	All targets in OG5_127057
Neospora caninum	hypothetical protein	Get druggable targets OG5_127057	All targets in OG5_127057
Leishmania donovani	isocitrate dehydrogenase [NADP], mitochondrial precursor, putative	Get druggable targets OG5_127057	All targets in OG5_127057
Plasmodium yoelii	isocitrate dehydrogenase, NADP-dependent, putative	Get druggable targets OG5_127057	All targets in OG5_127057
Neospora caninum	Isocitrate dehydrogenase-like protein, related	Get druggable targets OG5_127057	All targets in OG5_127057
Candida albicans	Mitochondrial NADP-specific isocitrate dehydrogenase	Get druggable targets OG5_127057	All targets in OG5_127057
Schistosoma mansoni	NADP-specific isocitrate dehydrogenase	Get druggable targets OG5_127057	All targets in OG5_127057
Schistosoma japonicum	ko:K00031 isocitrate dehydrogenase [EC1.1.1.42], putative	Get druggable targets OG5_127057	All targets in OG5_127057
Echinococcus multilocularis	isocitrate dehydrogenase	Get druggable targets OG5_127057	All targets in OG5_127057

By sequence similarity to non orthologous known druggable targets

Species	Potential target	Known druggable target	Length	Alignment span	Identity
Brugia malayi	MH2 domain containing protein	SMAD family member 2	467 aa	405 aa	31.6 %

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Loa Loa (eye worm)	beta-LACTamase domain containing family member	0.0036	0.0124	0.0124
Loa Loa (eye worm)	CMGC/MAPK/ERK1 protein kinase	0.0051	0.071	0.071
Leishmania major	CAAX prenyl protease 2, putative,peptidase with unknown catalytic mechanism (family U48)	0.0102	0.2717	1
Trichomonas vaginalis	CMGC family protein kinase	0.0051	0.071	0.0594
Trichomonas vaginalis	glucosylceramidase, putative	0.0189	0.6118	0.607
Toxoplasma gondii	glycosyl hydrolase, family 31 protein	0.0036	0.0129	0.0086
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0044	0.0441	0.053
Schistosoma mansoni	family S12 unassigned peptidase (S12 family)	0.0036	0.0124	0.0131
Trichomonas vaginalis	glucosylceramidase, putative	0.0189	0.6118	0.607
Loa Loa (eye worm)	hypothetical protein	0.0036	0.0124	0.0124
Trypanosoma cruzi	hypothetical protein, conserved	0.0036	0.0129	0.0022
Leishmania major	mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440	0.0051	0.071	0.2261
Loa Loa (eye worm)	RNA recognition domain-containing protein domain-containing protein	0.0071	0.148	0.148
Trypanosoma cruzi	mitogen activated protein kinase 2, putative	0.0051	0.071	0.2261
Loa Loa (eye worm)	MH2 domain-containing protein	0.0144	0.4354	0.4354
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0044	0.0441	0.0468
Trichomonas vaginalis	alpha-glucosidase, putative	0.0036	0.0129	0.0006
Echinococcus multilocularis	CAAX prenyl protease 2	0.0102	0.2717	0.4326
Trichomonas vaginalis	alpha-glucosidase, putative	0.0036	0.0129	0.0006
Trichomonas vaginalis	alpha-glucosidase, putative	0.0036	0.0129	0.0006
Brugia malayi	GTP-binding regulatory protein Gs alpha-S chain, putative	0.0044	0.0441	0.0441
Brugia malayi	RNA recognition motif domain containing protein	0.0071	0.148	0.148
Plasmodium vivax	ataxin-2 like protein, putative	0.0053	0.0803	1
Loa Loa (eye worm)	glycosyl hydrolase family 31 protein	0.0163	0.5101	0.5101
Trichomonas vaginalis	glucosylceramidase, putative	0.0189	0.6118	0.607
Schistosoma mansoni	serine/threonine protein kinase	0.0051	0.071	0.0753
Brugia malayi	Corticotropin releasing factor receptor 2 precursor, putative	0.0048	0.0596	0.0596
Trichomonas vaginalis	sucrase-isomaltase, putative	0.0036	0.0129	0.0006
Echinococcus granulosus	CAAX prenyl protease 2	0.0102	0.2717	0.4326
Loa Loa (eye worm)	hypothetical protein	0.0036	0.0124	0.0124
Mycobacterium tuberculosis	Probable short-chain type dehydrogenase/reductase	0.0057	0.0961	0.1101
Trichomonas vaginalis	CMGC family protein kinase	0.0051	0.071	0.0594
Echinococcus granulosus	geminin	0.0189	0.6118	1
Echinococcus granulosus	mitogen activated protein kinase 3	0.0051	0.071	0.0978
Trichomonas vaginalis	CMGC family protein kinase	0.0051	0.071	0.0594
Trypanosoma brucei	PAB1-binding protein , putative	0.0053	0.0803	0.2621
Brugia malayi	hypothetical protein	0.0035	0.0062	0.0062
Brugia malayi	RNA binding protein	0.0071	0.148	0.148
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0044	0.0441	0.053
Brugia malayi	MH2 domain containing protein	0.0144	0.4354	0.4354
Brugia malayi	Glycosyl hydrolases family 31 protein	0.0036	0.0129	0.0129
Trichomonas vaginalis	glucosylceramidase, putative	0.0189	0.6118	0.607
Schistosoma mansoni	tar DNA-binding protein	0.0071	0.148	0.157
Loa Loa (eye worm)	hypothetical protein	0.0036	0.0124	0.0124
Trypanosoma cruzi	peptidase with unknown catalytic mechanism (family U48)	0.0102	0.2717	1
Echinococcus multilocularis	mitogen activated protein kinase 3	0.0051	0.071	0.0978
Brugia malayi	beta-lactamase	0.0036	0.0124	0.0124
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0044	0.0441	0.0468
Trypanosoma cruzi	PAB1-binding protein , putative	0.0053	0.0803	0.2621
Plasmodium falciparum	ataxin-2 like protein, putative	0.0053	0.0803	0.5
Trichomonas vaginalis	alpha-glucosidase, putative	0.0036	0.0129	0.0006
Loa Loa (eye worm)	hypothetical protein	0.0036	0.0124	0.0124
Loa Loa (eye worm)	glycosyl hydrolase family 31 protein	0.0036	0.0129	0.0129
Toxoplasma gondii	LsmAD domain-containing protein	0.0053	0.0803	1
Brugia malayi	CAAX amino terminal protease family protein	0.0102	0.2717	0.2717
Trypanosoma cruzi	mitogen-activated protein kinase 11, putative	0.0051	0.071	0.2261
Loa Loa (eye worm)	GTP-binding regulatory protein Gs alpha-S chain	0.0044	0.0441	0.0441
Echinococcus granulosus	mitogen activated protein kinase	0.0051	0.071	0.0978
Echinococcus granulosus	neutral alpha glucosidase AB	0.0036	0.0129	0.001
Echinococcus multilocularis	tar DNA binding protein	0.0071	0.148	0.2263
Loa Loa (eye worm)	hypothetical protein	0.0048	0.0596	0.0596
Schistosoma mansoni	hypothetical protein	0.0189	0.6118	0.6487
Mycobacterium tuberculosis	Possible penicillin-binding protein	0.023	0.7733	1
Loa Loa (eye worm)	pigment dispersing factor receptor c	0.0048	0.0596	0.0596
Schistosoma mansoni	tar DNA-binding protein	0.0071	0.148	0.157
Loa Loa (eye worm)	TAR-binding protein	0.0071	0.148	0.148
Brugia malayi	hypothetical protein	0.0053	0.0803	0.0803
Trichomonas vaginalis	CMGC family protein kinase	0.0051	0.071	0.0594
Trichomonas vaginalis	Clan U, family U48, CaaX prenyl peptidase 2-like	0.0102	0.2717	0.2626
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0044	0.0441	0.053
Loa Loa (eye worm)	hypothetical protein	0.0036	0.0124	0.0124
Loa Loa (eye worm)	beta-lactamase	0.0036	0.0124	0.0124
Trichomonas vaginalis	neutral alpha-glucosidase ab precursor, putative	0.0036	0.0129	0.0006
Trichomonas vaginalis	neutral alpha-glucosidase ab precursor, putative	0.0036	0.0129	0.0006
Trichomonas vaginalis	glutaminase, putative	0.0274	0.9432	0.9425
Mycobacterium ulcerans	short-chain type dehydrogenase/reductase	0.0057	0.0961	0.09
Schistosoma mansoni	3-hydroxyacyl-CoA dehydrogenase	0.0057	0.0961	0.1019
Echinococcus granulosus	tar DNA binding protein	0.0071	0.148	0.2263
Mycobacterium leprae	Probable lipase LipE	0.0036	0.0124	0.5
Echinococcus granulosus	3 hydroxyacyl coenzyme A dehydrogenase type 2	0.0057	0.0961	0.1398
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0803	0.0803
Brugia malayi	Glycosyl hydrolases family 31 protein	0.0163	0.5101	0.5101
Schistosoma mansoni	tar DNA-binding protein	0.0071	0.148	0.157
Schistosoma mansoni	hypothetical protein	0.0189	0.6118	0.6487
Schistosoma mansoni	tar DNA-binding protein	0.0071	0.148	0.157
Brugia malayi	3-hydroxyacyl-CoA dehydrogenase type II	0.0057	0.0961	0.0961
Loa Loa (eye worm)	3-hydroxyacyl-CoA dehydrogenase type II	0.0054	0.081	0.081
Schistosoma mansoni	family U48 unassigned peptidase (U48 family)	0.0102	0.2717	0.288
Brugia malayi	beta-lactamase family protein	0.0036	0.0124	0.0124
Echinococcus granulosus	lysosomal alpha glucosidase	0.0163	0.5101	0.8303
Echinococcus multilocularis	geminin	0.0189	0.6118	1
Schistosoma mansoni	family U48 unassigned peptidase (U48 family)	0.0102	0.2717	0.288
Brugia malayi	TAR-binding protein	0.0071	0.148	0.148
Mycobacterium ulcerans	glutaminase	0.0274	0.9432	1
Trypanosoma brucei	glucosidase, putative	0.0036	0.0129	0.0022
Schistosoma mansoni	alpha-glucosidase	0.0141	0.4211	0.4465
Leishmania major	mitogen activated protein kinase, putative,map kinase, putative	0.0051	0.071	0.2261
Schistosoma mansoni	family S12 unassigned peptidase (S12 family)	0.0036	0.0124	0.0131
Trypanosoma brucei	mitogen activated protein kinase 4, putative	0.0051	0.071	0.2261
Leishmania major	hypothetical protein, conserved	0.0053	0.0803	0.2621
Entamoeba histolytica	CAAX prenyl protease family	0.0102	0.2717	1
Schistosoma mansoni	alpha glucosidase	0.0036	0.0129	0.0137
Trypanosoma cruzi	PAB1-binding protein , putative	0.0053	0.0803	0.2621
Plasmodium falciparum	ataxin-2 like protein, putative	0.0053	0.0803	0.5
Mycobacterium leprae	conserved hypothetical protein	0.0036	0.0124	0.5
Trypanosoma brucei	CAAX amino terminal protease, putative	0.0102	0.2717	1
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0044	0.0441	0.053
Brugia malayi	beta-lactamase family protein	0.0036	0.0124	0.0124
Leishmania major	alpha glucosidase II subunit, putative	0.0036	0.0129	0.0022
Loa Loa (eye worm)	glutaminase 2	0.0274	0.9432	0.9432
Trichomonas vaginalis	glucosylceramidase, putative	0.0199	0.6517	0.6473
Loa Loa (eye worm)	glutaminase	0.0274	0.9432	0.9432
Mycobacterium ulcerans	short-chain type dehydrogenase/reductase	0.0057	0.0961	0.09
Trichomonas vaginalis	glucosylceramidase, putative	0.0189	0.6118	0.607
Trichomonas vaginalis	maltase-glucoamylase, putative	0.0036	0.0129	0.0006
Trypanosoma cruzi	hypothetical protein, conserved	0.0036	0.0129	0.0022
Trichomonas vaginalis	glucosylceramidase, putative	0.0199	0.6517	0.6473
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0044	0.0441	0.0468
Leishmania major	3-oxoacyl-(acyl-carrier protein) reductase, putative	0.0057	0.0961	0.3231
Brugia malayi	Calcitonin receptor-like protein seb-1	0.0048	0.0596	0.0596
Schistosoma mansoni	glutaminase	0.0274	0.9432	1
Loa Loa (eye worm)	hypothetical protein	0.0102	0.2717	0.2717
Onchocerca volvulus		0.0094	0.2407	0.3809
Brugia malayi	MAP kinase sur-1	0.0051	0.071	0.071
Giardia lamblia	Hypothetical protein	0.0102	0.2717	1
Echinococcus multilocularis	lysosomal alpha glucosidase	0.0163	0.5101	0.8303
Trypanosoma brucei	protein kinase, putative	0.0051	0.071	0.2261
Brugia malayi	glutaminase DH11.1	0.0274	0.9432	0.9432
Trypanosoma cruzi	CAAX prenyl protease 2, putative	0.0102	0.2717	1
Echinococcus multilocularis	3 hydroxyacyl coenzyme A dehydrogenase type 2	0.0057	0.0961	0.1398
Trypanosoma cruzi	mitogen-activated protein kinase 11, putative	0.0051	0.071	0.2261
Schistosoma mansoni	alpha-glucosidase	0.0141	0.4211	0.4465
Brugia malayi	Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative	0.0036	0.0124	0.0124
Schistosoma mansoni	tar DNA-binding protein	0.0071	0.148	0.157
Trypanosoma cruzi	mitogen activated protein kinase 4, putative	0.0051	0.071	0.2261
Onchocerca volvulus	Glucosylceramidase homolog	0.0189	0.6118	1
Toxoplasma gondii	CMGC kinase, MAPK family (ERK) MAPK-1	0.0051	0.071	0.8626
Trichomonas vaginalis	glucosylceramidase, putative	0.0189	0.6118	0.607
Loa Loa (eye worm)	hypothetical protein	0.0036	0.0124	0.0124
Loa Loa (eye worm)	transcription factor SMAD2	0.0144	0.4354	0.4354
Trichomonas vaginalis	glucosylceramidase, putative	0.0189	0.6118	0.607
Echinococcus multilocularis	mitogen activated protein kinase	0.0051	0.071	0.0978
Loa Loa (eye worm)	RNA binding protein	0.0071	0.148	0.148
Echinococcus multilocularis	lysosomal alpha glucosidase	0.0163	0.5101	0.8303
Trichomonas vaginalis	alpha-glucosidase, putative	0.0036	0.0129	0.0006
Echinococcus multilocularis	neutral alpha glucosidase AB	0.0036	0.0129	0.001

Activities

Activity type	Activity value	Assay description	Source	Reference
Potency (functional)	18.3564 uM	PubChem BioAssay. qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-NT fibrosarcoma cell line. (Class of assay: confirmatory)	ChEMBL.	No reference
Potency (functional)	19.9526 uM	PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588856, AID588860]	ChEMBL.	No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL1874278

Bibliographic References

No literature references available for this target.

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Detailed information for compound 1186534