Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | alpha-glucosidase | 0.0607 | 0.8 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0201 | 0.124 | 0.4139 |
Echinococcus multilocularis | fucosidase, alpha L 1, tissue | 0.0477 | 0.5842 | 0.534 |
Schistosoma mansoni | alpha-l-fucosidase | 0.0289 | 0.2699 | 0.2342 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0201 | 0.124 | 0.4139 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0191 | 0.1078 | 0.3599 |
Brugia malayi | Alpha-L-fucosidase family protein | 0.0289 | 0.2699 | 0.2671 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0204 | 0.1289 | 0.1256 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0191 | 0.1078 | 0.1044 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0201 | 0.124 | 0.4139 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0306 | 0.2995 | 1 |
Onchocerca volvulus | 0.0232 | 0.1759 | 0.1047 | |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0201 | 0.124 | 0.4139 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0191 | 0.1078 | 0.3599 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0306 | 0.2995 | 1 |
Onchocerca volvulus | 0.0499 | 0.6198 | 1 | |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0306 | 0.2995 | 1 |
Brugia malayi | Pre-SET motif family protein | 0.0204 | 0.1289 | 0.1256 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0306 | 0.2995 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0191 | 0.1078 | 0.5 |
Echinococcus granulosus | tumor protein p63 | 0.066 | 0.8875 | 0.8739 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0191 | 0.1078 | 0.3599 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0212 | 0.142 | 0.4741 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0191 | 0.1078 | 0.3599 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0191 | 0.1078 | 0.3599 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0191 | 0.1078 | 0.3599 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0191 | 0.1078 | 0.5 |
Echinococcus granulosus | fucosidase alpha L 1 tissue | 0.0477 | 0.5842 | 0.534 |
Trichomonas vaginalis | set domain proteins, putative | 0.0232 | 0.1759 | 0.5873 |
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.0191 | 0.1078 | 0.3599 |
Trypanosoma brucei | glucosidase, putative | 0.0191 | 0.1078 | 0.5 |
Mycobacterium ulcerans | alpha-L-fucosidase | 0.0477 | 0.5842 | 0.5 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0191 | 0.1078 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0201 | 0.124 | 0.4139 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0306 | 0.2995 | 1 |
Echinococcus multilocularis | tumor protein p63 | 0.066 | 0.8875 | 0.8739 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0191 | 0.1078 | 0.5 |
Loa Loa (eye worm) | alpha-L-fucosidase | 0.0289 | 0.2699 | 0.2671 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0201 | 0.124 | 0.4139 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0306 | 0.2995 | 1 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0191 | 0.1078 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0191 | 0.1078 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0201 | 0.124 | 0.4139 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0191 | 0.1078 | 0.3599 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0212 | 0.142 | 0.4741 |
Schistosoma mansoni | alpha-glucosidase | 0.0607 | 0.8 | 1 |
Brugia malayi | O-Glycosyl hydrolase family 30 protein | 0.0306 | 0.2995 | 0.2968 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0191 | 0.1078 | 0.3599 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.0306 | 0.2995 | 0.2968 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0191 | 0.1078 | 0.1044 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.