Detailed information for compound 1203049

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 317.32 | Formula: C18H12FN5
  • H donors: 1 H acceptors: 4 LogP: 2.83 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: Fc1ccc2c(c1)C(=NNC(=N2)c1cccnc1)c1ccncc1
  • InChi: 1S/C18H12FN5/c19-14-3-4-16-15(10-14)17(12-5-8-20-9-6-12)23-24-18(22-16)13-2-1-7-21-11-13/h1-11H,(H,22,24)
  • InChiKey: XDHWUECUNCKDNN-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Influenza A virus Nonstructural protein 1 Starlite/ChEMBL No references
Candida albicans hypothetical protein Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Cryptosporidium hominis heat shock protein 83 Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei gambiense lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania braziliensis lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei gambiense Heat shock protein 83, putative Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus multilocularis heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania mexicana heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania mexicana lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei Heat shock protein 83, putative Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma cruzi heat shock protein 85, putative Get druggable targets OG5_126623 All targets in OG5_126623
Toxoplasma gondii heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative Get druggable targets OG5_126623 All targets in OG5_126623
Loa Loa (eye worm) endoplasmin Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma japonicum ko:K04079 molecular chaperone HtpG, putative Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Giardia lamblia Grp94/Hsp90 Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma japonicum Heat shock protein 83, putative Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma mansoni endoplasmin Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania donovani heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus granulosus heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma congolense heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Theileria parva heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Entamoeba histolytica heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Trichomonas vaginalis heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Candida albicans heat shock protein Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Plasmodium knowlesi heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei gambiense Heat shock protein 83, putative Get druggable targets OG5_126623 All targets in OG5_126623
Trichomonas vaginalis heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania infantum heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Neospora caninum HSP90, related Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma japonicum ko:K09487 heat shock protein 90kDa beta, putative Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma cruzi heat shock protein 85, putative Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma mansoni endoplasmin Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania braziliensis heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Brugia malayi heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Candida albicans heat shock protein Get druggable targets OG5_126623 All targets in OG5_126623
Plasmodium falciparum heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Brugia malayi Endoplasmin precursor Get druggable targets OG5_126623 All targets in OG5_126623
Cryptosporidium parvum Hsp90 Get druggable targets OG5_126623 All targets in OG5_126623
Loa Loa (eye worm) heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma japonicum Heat shock protein HSP 90-beta, putative Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus granulosus endoplasmin Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus multilocularis heat shock protein Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei gambiense heat shock protein 83,heat shock protein Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma cruzi Heat shock protein 83, putative Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania infantum heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma cruzi heat shock protein 85, putative Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus multilocularis heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania infantum heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma cruzi heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma mansoni heat shock protein Get druggable targets OG5_126623 All targets in OG5_126623
Plasmodium yoelii heat shock 90 kDa protein homolog Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania braziliensis heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus multilocularis endoplasmin Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus granulosus heat shock protein Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Toxoplasma gondii heat shock protein HSP90 Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma congolense heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Neospora caninum HSP90-like protein, related Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma cruzi heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Treponema pallidum heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania infantum lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma japonicum Heat shock protein HSP 90-alpha, putative Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma japonicum IPR003367,Thrombospondin type 3 repeat;IPR002048,Calcium-binding EF-hand,domain-containing Get druggable targets OG5_126623 All targets in OG5_126623
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Plasmodium vivax endoplasmin, putative Get druggable targets OG5_126623 All targets in OG5_126623
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Entamoeba histolytica heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma congolense Heat shock protein 83, putative Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Plasmodium yoelii putative heat shock protein 81-2 Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania braziliensis heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus granulosus heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma cruzi heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Babesia bovis hsp90 protein Get druggable targets OG5_126623 All targets in OG5_126623
Mycobacterium ulcerans heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Giardia lamblia Heat shock protein HSP 90-alpha Get druggable targets OG5_126623 All targets in OG5_126623
Giardia lamblia Heat shock protein HSP 90-alpha Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania donovani heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma mansoni heat shock protein Get druggable targets OG5_126623 All targets in OG5_126623
Plasmodium yoelii heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Trichomonas vaginalis heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania mexicana heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Trichomonas vaginalis heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Candida albicans hypothetical protein Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma cruzi heat shock protein 85, putative Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus granulosus heat shock protein heat shock protein 90 alpha Get druggable targets OG5_126623 All targets in OG5_126623
Plasmodium vivax heat shock protein 86, putative Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) Get druggable targets OG5_126623 All targets in OG5_126623
Plasmodium berghei heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Plasmodium knowlesi endoplasmin, putative Get druggable targets OG5_126623 All targets in OG5_126623
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Mycobacterium tuberculosis Hypothetical protein Nonstructural protein 1   230 aa 202 aa 23.8 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma cruzi Heat shock protein 83, putative 0.0039 0.4661 0.6045
Plasmodium falciparum heat shock protein 90 0.0039 0.4661 0.6045
Plasmodium vivax ataxin-2 like protein, putative 0.0054 0.771 1
Echinococcus multilocularis heat shock protein 90 0.0039 0.4661 0.4661
Trypanosoma cruzi heat shock protein 85, putative 0.0039 0.4661 0.6045
Toxoplasma gondii heat shock protein HSP90 0.0039 0.4661 0.4661
Trypanosoma brucei PAB1-binding protein , putative 0.0054 0.771 1
Leishmania major heat shock protein 83-1 0.0039 0.4661 0.4661
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0066 1 1
Giardia lamblia Heat shock protein HSP 90-alpha 0.0039 0.4661 1
Trypanosoma brucei heat shock protein, putative 0.0039 0.4661 0.6045
Leishmania major heat shock protein 83-1 0.0039 0.4661 0.4661
Leishmania major heat shock protein 83-1 0.0039 0.4661 0.4661
Trichomonas vaginalis heat shock protein, putative 0.0031 0.3052 0.655
Loa Loa (eye worm) endoplasmin 0.0039 0.4661 0.6045
Trichomonas vaginalis heat shock protein, putative 0.0039 0.4661 1
Loa Loa (eye worm) heat shock protein 90 0.0039 0.4661 0.6045
Echinococcus multilocularis endoplasmin 0.0031 0.3052 0.3052
Echinococcus multilocularis heat shock protein 0.0039 0.4661 0.4661
Echinococcus granulosus heat shock protein 90 0.0031 0.3052 0.3052
Schistosoma mansoni aldehyde dehydrogenase 0.0066 1 1
Leishmania major hypothetical protein, conserved 0.0054 0.771 0.771
Brugia malayi Endoplasmin precursor 0.0039 0.4661 0.6045
Brugia malayi heat shock protein 90 0.0039 0.4661 0.6045
Leishmania major heat shock protein 83-1 0.0039 0.4661 0.4661
Leishmania major heat shock protein 83-1 0.0039 0.4661 0.4661
Trypanosoma brucei heat shock protein, putative 0.0039 0.4661 0.6045
Trypanosoma cruzi heat shock protein 90, putative 0.0023 0.1425 0.1848
Trypanosoma cruzi heat shock protein 85, putative 0.0039 0.4661 0.6045
Schistosoma mansoni endoplasmin 0.0039 0.4661 0.4661
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0031 0.3052 0.5
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0016 0 0.5
Toxoplasma gondii LsmAD domain-containing protein 0.0054 0.771 0.771
Trypanosoma brucei heat shock protein, putative 0.0039 0.4661 0.6045
Trichomonas vaginalis heat shock protein, putative 0.0031 0.3052 0.655
Echinococcus granulosus endoplasmin 0.0031 0.3052 0.3052
Trichomonas vaginalis heat shock protein, putative 0.0024 0.1608 0.345
Trypanosoma cruzi PAB1-binding protein , putative 0.0054 0.771 1
Echinococcus granulosus heat shock protein 0.0039 0.4661 0.4661
Leishmania major heat shock protein 83-1 0.0039 0.4661 0.4661
Schistosoma mansoni heat shock protein 0.0039 0.4661 0.4661
Trypanosoma cruzi heat shock protein 90, putative 0.0031 0.3052 0.3959
Brugia malayi hypothetical protein 0.0035 0.3831 0.4969
Trypanosoma brucei heat shock protein 90, putative 0.0039 0.4661 0.6045
Leishmania major heat shock protein 83-1 0.0039 0.4661 0.4661
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0031 0.3052 0.5
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0024 0.1674 0.1674
Trypanosoma brucei heat shock protein, putative 0.0039 0.4661 0.6045
Trypanosoma brucei heat shock protein, putative 0.0039 0.4661 0.6045
Mycobacterium ulcerans aldehyde dehydrogenase 0.0066 1 1
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0031 0.3052 0.3052
Trypanosoma brucei heat shock protein, putative 0.0039 0.4661 0.6045
Leishmania major heat shock protein 83-1 0.0039 0.4661 0.4661
Leishmania major heat shock protein 83-1 0.0039 0.4661 0.4661
Trypanosoma cruzi heat shock protein 90, putative 0.0039 0.4661 0.6045
Schistosoma mansoni endoplasmin 0.0039 0.4661 0.4661
Treponema pallidum heat shock protein 90 0.0031 0.3052 0.5
Mycobacterium ulcerans aldehyde dehydrogenase 0.0066 1 1
Plasmodium falciparum endoplasmin, putative 0.0024 0.1608 0.2086
Echinococcus granulosus heat shock protein 90 0.0039 0.4661 0.4661
Entamoeba histolytica heat shock protein 90, putative 0.0039 0.4661 1
Trypanosoma brucei heat shock protein, putative 0.0039 0.4661 0.6045
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0031 0.3052 0.3052
Leishmania major heat shock protein 83-1 0.0039 0.4661 0.4661
Toxoplasma gondii aldehyde dehydrogenase 0.0066 1 1
Schistosoma mansoni aldehyde dehydrogenase 0.0066 1 1
Trypanosoma brucei Heat shock protein 83, putative 0.0039 0.4661 0.6045
Mycobacterium ulcerans aldehyde dehydrogenase 0.0066 1 1
Leishmania major heat shock protein 83-1 0.0039 0.4661 0.4661
Leishmania major heat shock protein 83-1 0.0039 0.4661 0.4661
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0066 1 1
Trypanosoma cruzi PAB1-binding protein , putative 0.0054 0.771 1
Plasmodium falciparum ataxin-2 like protein, putative 0.0054 0.771 1
Toxoplasma gondii heat shock protein 90, putative 0.0039 0.4661 0.4661
Leishmania major heat shock protein 83-1 0.0039 0.4661 0.4661
Plasmodium falciparum ataxin-2 like protein, putative 0.0054 0.771 1
Plasmodium vivax heat shock protein 86, putative 0.0039 0.4661 0.6045
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0066 1 1
Trichomonas vaginalis endoplasmin, putative 0.0024 0.1608 0.345
Leishmania major heat shock protein 83-1 0.0039 0.4661 0.4661
Entamoeba histolytica heat shock protein 90, putative 0.0039 0.4661 1
Trypanosoma cruzi heat shock protein 85, putative 0.0031 0.3052 0.3959
Leishmania major heat shock protein 83-1 0.0039 0.4661 0.4661
Trypanosoma brucei heat shock protein 90, putative 0.0039 0.4661 0.6045
Leishmania major heat shock protein 83-1 0.0039 0.4661 0.4661
Trypanosoma cruzi heat shock protein 85, putative 0.0039 0.4661 0.6045
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0024 0.1674 0.1674
Schistosoma mansoni heat shock protein 0.0039 0.4661 0.4661
Trypanosoma brucei heat shock protein, putative 0.0039 0.4661 0.6045
Echinococcus multilocularis heat shock protein 90 0.0031 0.3052 0.3052
Leishmania major heat shock protein 83-1 0.0039 0.4661 0.4661
Brugia malayi hypothetical protein 0.0054 0.771 1
Plasmodium vivax endoplasmin, putative 0.0039 0.4661 0.6045
Loa Loa (eye worm) hypothetical protein 0.0054 0.771 1
Trichomonas vaginalis heat shock protein, putative 0.0031 0.3052 0.655
Schistosoma mansoni hypothetical protein 0.0024 0.1674 0.1674

Activities

Activity type Activity value Assay description Source Reference
EC50 (functional) = 0.964 uM PUBCHEM_BIOASSAY: Fluorescence Cell-Based Secondary Assay to Identify Inhibitors of Resistant C. albicans Growth in the Presence of Fluconazole. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1979, AID2007] ChEMBL. No reference
Potency (functional) 0.0026 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 0.3696 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) = 12.5893 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Influenza NS1 Protein Function. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 35.4813 um PUBCHEM_BIOASSAY: qHTS Multiplex Assay to Identify Dual Action Probes in a Cell Model of Huntington: Aggregate Formation (GFP). (Class of assay: confirmatory) [Related pubchem assays: 1482, 1471 ] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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