Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | macrophage migration inhibitory factor (glycosylation-inhibiting factor) | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.2526 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0133 | 0.0147 |
Loa Loa (eye worm) | macrophage migration inhibitory factor 2 | 0.0087 | 0.3772 | 0.4011 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0035 | 0.1435 | 0.5 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0035 | 0.1435 | 0.5614 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.1435 | 0.1359 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0133 | 0.0147 |
Onchocerca volvulus | 0.0035 | 0.1435 | 1 | |
Loa Loa (eye worm) | beta-lactamase | 0.0035 | 0.1435 | 0.1359 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0053 | 0.2248 | 0.1067 |
Toxoplasma gondii | macrophage migration inhibitory factor, putative | 0.0205 | 0.905 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0133 | 0.0147 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.006 | 0.2526 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0133 | 0.0147 |
Mycobacterium leprae | Probable lipase LipE | 0.0035 | 0.1435 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0133 | 0.0147 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.1186 | 0.4619 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.006 | 0.2526 | 0.9965 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0006 | 0.0133 | 0.0147 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0133 | 0.0147 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0238 | 0.0327 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0035 | 0.1435 | 0.5 |
Brugia malayi | CXXC zinc finger family protein | 0.0028 | 0.1114 | 0.0999 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0133 | 0.0147 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.1435 | 0.1359 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.1435 | 0.1359 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0035 | 0.1435 | 0.1586 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0133 | 0.0147 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0035 | 0.1435 | 0.1363 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0133 | 0.0147 |
Echinococcus multilocularis | cpg binding protein | 0.003 | 0.1186 | 0.4334 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.006 | 0.2526 | 0.9965 |
Brugia malayi | beta-lactamase | 0.0035 | 0.1435 | 0.1363 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0035 | 0.1435 | 0.1586 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0238 | 0.0327 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0133 | 0.0147 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.2526 | 1 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0035 | 0.1435 | 0.5388 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0205 | 0.905 | 1 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0035 | 0.1435 | 0.5388 |
Echinococcus granulosus | cpg binding protein | 0.003 | 0.1186 | 0.4334 |
Plasmodium falciparum | macrophage migration inhibitory factor | 0.0205 | 0.905 | 0.5 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.006 | 0.2526 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0133 | 0.0147 |
Brugia malayi | Bm-MIF-1, identical | 0.0205 | 0.905 | 1 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0035 | 0.1435 | 0.5 |
Trichomonas vaginalis | macrophage migration inhibitory factor, mif, putative | 0.0205 | 0.905 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0133 | 0.0147 |
Brugia malayi | beta-lactamase family protein | 0.0035 | 0.1435 | 0.1363 |
Onchocerca volvulus | 0.0035 | 0.1435 | 1 | |
Plasmodium vivax | macrophage migration inhibitory factor, putative | 0.0205 | 0.905 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0133 | 0.0147 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0035 | 0.1435 | 0.1586 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.006 | 0.2526 | 0.1433 |
Giardia lamblia | Macrophage migration inhibitory factor | 0.0205 | 0.905 | 0.5 |
Leishmania major | macrophage migration inhibitory factor-like protein | 0.0205 | 0.905 | 1 |
Mycobacterium leprae | conserved hypothetical protein | 0.0035 | 0.1435 | 0.5 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0035 | 0.1435 | 0.1359 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.006 | 0.2535 | 1 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.006 | 0.2526 | 0.1274 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0028 | 0.1114 | 0.0994 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.006 | 0.2526 | 0.1433 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0035 | 0.1435 | 0.1586 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0133 | 0.0147 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0007 | 0.0161 | 0.0531 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0133 | 0.0147 |
Trichomonas vaginalis | esterase, putative | 0.0035 | 0.1435 | 0.1586 |
Brugia malayi | beta-lactamase family protein | 0.0035 | 0.1435 | 0.1363 |
Schistosoma mansoni | cpg binding protein | 0.0028 | 0.1114 | 0.4331 |
Leishmania major | macrophage migration inhibitory factor-like protein | 0.0205 | 0.905 | 1 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.2526 | 1 |
Loa Loa (eye worm) | macrophage migration inhibitory factor 2 | 0.0087 | 0.3772 | 0.4011 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.1435 | 0.1359 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.1435 | 0.1359 |
Loa Loa (eye worm) | macrophage migration inhibitory factor | 0.0205 | 0.905 | 1 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0035 | 0.1435 | 0.5614 |
Trichomonas vaginalis | helicase, putative | 0.0006 | 0.0133 | 0.0147 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.1186 | 0.4619 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.1435 | 0.1359 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0006 | 0.0133 | 0.0147 |
Entamoeba histolytica | macrophage migration inhibitory factor-like protein | 0.0205 | 0.905 | 0.5 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0035 | 0.1435 | 0.1586 |
Onchocerca volvulus | 0.0035 | 0.1435 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.