TDR Targets

Basic information

Technical information

TDR Targets ID: 1310865
Name: (2-tert-butylpyridin-4-yl)-(4-pyrimidin-2-ylp iperazin-1-yl)methanone
MW: 325.408 | Formula: C18H23N5O
H donors: 0 H acceptors: 4 LogP: 2.23 Rotable bonds: 4
Rule of 5 violations (Lipinski): 1
SMILES: O=C(c1ccnc(c1)C(C)(C)C)N1CCN(CC1)c1ncccn1
InChi: 1S/C18H23N5O/c1-18(2,3)15-13-14(5-8-19-15)16(24)22-9-11-23(12-10-22)17-20-6-4-7-21-17/h4-8,13H,9-12H2,1-3H3
InChiKey: HVAVGLPEMPVGJJ-UHFFFAOYSA-N

Network

Hover on a compound node to display the structore

Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

This is a work in progress. Come back soon to try this features!

Clustering layers

This is a work in progress. Come back soon to try this features!

Synonyms

(2-tert-butyl-4-pyridyl)-(4-pyrimidin-2-ylpiperazin-1-yl)methanone
(2-tert-butyl-4-pyridyl)-[4-(2-pyrimidinyl)-1-piperazinyl]methanone
SMR000076945
MLS000063983
ZINC00347163
2-[4-(2-tert-butylisonicotinoyl)-1-piperazinyl]pyrimidine
STOCK4S-55921

Targets

Known targets for this compound

Species	Target name	Source	Bibliographic reference
Homo sapiens	survival of motor neuron 2, centromeric	Starlite/ChEMBL	No references
Mus musculus	RAR-related orphan receptor gamma	Starlite/ChEMBL	No references
Homo sapiens	GNAS complex locus	Starlite/ChEMBL	No references
Homo sapiens	nuclear factor, erythroid 2-like 2	Starlite/ChEMBL	No references

Predicted pathogen targets for this compound

By orthology

Species	Potential target	Known druggable target/s	Ortholog Group
Schistosoma japonicum	ko:K04632 guanine nucleotide binding protein (G protein), alpha stimulating, putative	Get druggable targets OG5_131088	All targets in OG5_131088
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	Get druggable targets OG5_131088	All targets in OG5_131088
Echinococcus multilocularis	survival motor neuron protein 1	Get druggable targets OG5_132873	All targets in OG5_132873
Brugia malayi	GTP-binding regulatory protein Gs alpha-S chain, putative	Get druggable targets OG5_131088	All targets in OG5_131088
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	Get druggable targets OG5_131088	All targets in OG5_131088
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	Get druggable targets OG5_131088	All targets in OG5_131088
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	Get druggable targets OG5_131088	All targets in OG5_131088
Echinococcus granulosus	survival motor neuron protein 1	Get druggable targets OG5_132873	All targets in OG5_132873
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	Get druggable targets OG5_131088	All targets in OG5_131088
Brugia malayi	hypothetical protein	Get druggable targets OG5_132873	All targets in OG5_132873
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	Get druggable targets OG5_131088	All targets in OG5_131088
Loa Loa (eye worm)	GTP-binding regulatory protein Gs alpha-S chain	Get druggable targets OG5_131088	All targets in OG5_131088
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	Get druggable targets OG5_131088	All targets in OG5_131088
Loa Loa (eye worm)	hypothetical protein	Get druggable targets OG5_132873	All targets in OG5_132873

By sequence similarity to non orthologous known druggable targets

Species	Potential target	Known druggable target	Length	Alignment span	Identity
Schistosoma mansoni	GTP-binding protein alpha subunit gna	GNAS complex locus	394 aa	450 aa	28.7 %

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.0012	0.0027	0.003
Trichomonas vaginalis	flap endonuclease-1, putative	0.0026	0.0469	0.5
Trypanosoma brucei	variant surface glycoprotein (VSG), putative	0.0111	0.3238	1
Loa Loa (eye worm)	hypothetical protein	0.0018	0.0201	0.0174
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0055	0.1429	0.7257
Brugia malayi	hypothetical protein	0.0025	0.0456	0.043
Loa Loa (eye worm)	hypothetical protein	0.0016	0.0138	0.0111
Trypanosoma cruzi	calpain-like cysteine peptidase, putative	0.0111	0.3238	1
Trypanosoma cruzi	flap endonuclease-1 (FEN-1), putative	0.0026	0.0469	0.0048
Entamoeba histolytica	Flap nuclease, putative	0.0026	0.0469	0.0478
Echinococcus granulosus	tar DNA binding protein	0.0064	0.1706	0.191
Brugia malayi	GTP-binding regulatory protein Gs alpha-S chain, putative	0.0055	0.1429	0.1406
Echinococcus multilocularis	survival motor neuron protein 1	0.0286	0.8933	1
Toxoplasma gondii	flap structure-specific endonuclease 1, putative	0.0026	0.0469	1
Echinococcus granulosus	GPCR family 2	0.0016	0.0138	0.0154
Leishmania major	calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative	0.0111	0.3238	1
Schistosoma mansoni	tar DNA-binding protein	0.0064	0.1706	0.8665
Loa Loa (eye worm)	hypothetical protein	0.0027	0.0507	0.0481
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0394	0.0368
Plasmodium falciparum	flap endonuclease 1	0.0026	0.0469	1
Chlamydia trachomatis	acylglycerophosphoethanolamine acyltransferase	0.0018	0.0201	0.5
Brugia malayi	Temporarily assigned gene name protein 44	0.0027	0.0507	0.0481
Trypanosoma brucei	flap endonuclease-1 (FEN-1), putative	0.0026	0.0469	0.0048
Leishmania major	flap endonuclease-1 (FEN-1), putative	0.0026	0.0469	0.0265
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0055	0.1429	0.7257
Trypanosoma brucei	calpain-like cysteine peptidase, putative	0.0111	0.3238	1
Brugia malayi	RNA binding protein	0.0064	0.1706	0.1684
Echinococcus multilocularis	GPCR, family 2	0.0016	0.0138	0.0154
Mycobacterium tuberculosis	Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase)	0.0023	0.0394	1
Schistosoma mansoni	photoreceptor-specific nuclear receptor related	0.0012	0.0027	0.0137
Echinococcus granulosus	COUP TF:Svp nuclear hormone receptor	0.0012	0.0027	0.003
Echinococcus multilocularis	flap endonuclease 1	0.0026	0.0469	0.0525
Loa Loa (eye worm)	pigment dispersing factor receptor c	0.0049	0.1237	0.1213
Loa Loa (eye worm)	hypothetical protein	0.0018	0.0201	0.0174
Echinococcus granulosus	diuretic hormone 44 receptor GPRdih2	0.0016	0.0138	0.0154
Mycobacterium ulcerans	acyl-CoA synthetase	0.0023	0.0394	1
Schistosoma mansoni	hypothetical protein	0.0016	0.0138	0.0701
Echinococcus multilocularis	cadherin EGF LAG seven pass G type receptor	0.0016	0.0138	0.0154
Brugia malayi	AMP-binding enzyme family protein	0.0023	0.0394	0.0368
Onchocerca volvulus		0.0058	0.1527	1
Leishmania major	calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative	0.0111	0.3238	1
Echinococcus granulosus	retinoic acid receptor rxr beta a	0.0012	0.0027	0.003
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0055	0.1429	0.16
Loa Loa (eye worm)	GTP-binding regulatory protein Gs alpha-S chain	0.0055	0.1429	0.1406
Mycobacterium tuberculosis	Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase)	0.0018	0.0201	0.139
Schistosoma mansoni	nuclear receptor 2DBD-gamma	0.0012	0.0027	0.0137
Mycobacterium leprae	PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE)	0.0023	0.0394	0.5
Trypanosoma cruzi	calpain cysteine peptidase, putative	0.0111	0.3238	1
Brugia malayi	Calcitonin receptor-like protein seb-1	0.0049	0.1237	0.1213
Echinococcus granulosus	ecdysone induced protein 78C	0.0012	0.0027	0.003
Trypanosoma brucei	calpain-like cysteine peptidase, putative	0.0111	0.3238	1
Schistosoma mansoni	tar DNA-binding protein	0.0064	0.1706	0.8665
Brugia malayi	hypothetical protein	0.0286	0.8933	0.893
Brugia malayi	Iron-sulfur cluster assembly accessory protein	0.0058	0.1527	0.1504
Loa Loa (eye worm)	RNA binding protein	0.0064	0.1706	0.1684
Leishmania major	hypothetical protein, conserved	0.0025	0.0456	0.0217
Loa Loa (eye worm)	flap endonuclease-1	0.0026	0.0469	0.0443
Echinococcus granulosus	survival motor neuron protein 1	0.0286	0.8933	1
Loa Loa (eye worm)	hypothetical protein	0.0018	0.0201	0.0174
Echinococcus multilocularis	Basic leucine zipper (bZIP) transcription	0.0072	0.1969	0.2204
Mycobacterium ulcerans	hypothetical protein	0.0023	0.0394	1
Echinococcus multilocularis	hepatocyte nuclear factor 4 alpha	0.0012	0.0027	0.003
Schistosoma mansoni	coup transcription factor	0.0012	0.0027	0.0137
Loa Loa (eye worm)	hypothetical protein	0.0034	0.0728	0.0703
Schistosoma mansoni	nuclear hormone receptor nor-1/nor-2	0.0012	0.0027	0.0137
Entamoeba histolytica	hypothetical protein	0.0072	0.1969	1
Mycobacterium ulcerans	acyl-CoA synthetase	0.0023	0.0394	1
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0394	0.0368
Brugia malayi	calcium-independent alpha-latrotoxin receptor 2, putative	0.0016	0.0138	0.0111
Schistosoma mansoni	retinoic acid receptor RXR	0.0012	0.0027	0.0137
Brugia malayi	hypothetical protein	0.0072	0.1969	0.1947
Trypanosoma cruzi	calpain-like cysteine peptidase, putative	0.0111	0.3238	1
Echinococcus multilocularis	COUP TF:Svp nuclear hormone receptor	0.0012	0.0027	0.003
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0055	0.1429	0.16
Brugia malayi	TAR-binding protein	0.0064	0.1706	0.1684
Brugia malayi	latrophilin 2 splice variant baaae	0.0034	0.0728	0.0703
Mycobacterium ulcerans	long-chain fatty-acid CoA ligase	0.0023	0.0394	1
Brugia malayi	Corticotropin releasing factor receptor 2 precursor, putative	0.0049	0.1237	0.1213
Brugia malayi	hypothetical protein	0.0016	0.0163	0.0136
Plasmodium vivax	ataxin-2 like protein, putative	0.0025	0.0456	0.9501
Echinococcus multilocularis	ecdysone induced protein 78C	0.0012	0.0027	0.003
Brugia malayi	AMP-binding enzyme family protein	0.0023	0.0394	0.0368
Plasmodium falciparum	ataxin-2 like protein, putative	0.0025	0.0456	0.9501
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0055	0.1429	0.16
Echinococcus multilocularis	Nuclear hormone receptor family member nhr 41	0.0012	0.0027	0.003
Echinococcus multilocularis	FTZ F1 nuclear receptor protein	0.0012	0.0027	0.003
Loa Loa (eye worm)	hypothetical protein	0.0018	0.0201	0.0174
Schistosoma mansoni	RAR-like nuclear receptor	0.0012	0.0027	0.0137
Schistosoma mansoni	tar DNA-binding protein	0.0064	0.1706	0.8665
Onchocerca volvulus		0.0023	0.0394	0.2446
Mycobacterium ulcerans	long-chain-fatty-acid-CoA ligase	0.0023	0.0394	1
Entamoeba histolytica	hypothetical protein	0.0072	0.1969	1
Echinococcus granulosus	cadherin EGF LAG seven pass G type receptor	0.0016	0.0138	0.0154
Schistosoma mansoni	hypothetical protein	0.0058	0.1527	0.7755
Trypanosoma brucei	calpain-like cysteine peptidase, putative	0.0111	0.3238	1
Loa Loa (eye worm)	hypothetical protein	0.0286	0.8933	0.893
Schistosoma mansoni	survival motor neuron protein	0.0058	0.1527	0.7755
Schistosoma mansoni	thyroid hormone receptor	0.0012	0.0027	0.0137
Loa Loa (eye worm)	tumor suppressor	0.0318	1	1
Brugia malayi	Flap endonuclease-1	0.0026	0.0469	0.0443
Schistosoma mansoni	hypothetical protein	0.0016	0.0138	0.0701
Trypanosoma cruzi	calpain-like cysteine peptidase, putative	0.0111	0.3238	1
Brugia malayi	Latrophilin receptor protein 2	0.0016	0.0138	0.0111
Schistosoma mansoni	hypothetical protein	0.0016	0.0138	0.0701
Loa Loa (eye worm)	latrophilin receptor protein 2	0.0016	0.0138	0.0111
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.0012	0.0027	0.003
Schistosoma mansoni	tar DNA-binding protein	0.0064	0.1706	0.8665
Schistosoma mansoni	transcription factor LCR-F1	0.0072	0.1969	1
Schistosoma mansoni	thyroid hormone receptor	0.0012	0.0027	0.0137
Brugia malayi	RNA recognition motif domain containing protein	0.0064	0.1706	0.1684
Trypanosoma brucei	calpain-like cysteine peptidase, putative	0.0111	0.3238	1
Loa Loa (eye worm)	hypothetical protein	0.0025	0.0456	0.043
Brugia malayi	hypothetical protein	0.0027	0.0507	0.0481
Leishmania major	calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative	0.0111	0.3238	1
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0394	0.0368
Mycobacterium ulcerans	long-chain-fatty-acid--CoA ligase	0.0023	0.0394	1
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.0012	0.0027	0.003
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0023	0.0394	1
Entamoeba histolytica	hypothetical protein	0.0072	0.1969	1
Loa Loa (eye worm)	hypothetical protein	0.0049	0.1237	0.1213
Schistosoma mansoni	hypothetical protein	0.0016	0.0138	0.0701
Trypanosoma brucei	hypothetical protein	0.0111	0.3238	1
Brugia malayi	AMP-binding enzyme family protein	0.0023	0.0394	0.0368
Schistosoma mansoni	hypothetical protein	0.0027	0.0507	0.2573
Schistosoma mansoni	flap endonuclease-1	0.0023	0.0388	0.1973
Schistosoma mansoni	FTZ-F1 nuclear receptor-like protein	0.0012	0.0027	0.0137
Schistosoma mansoni	hypothetical protein	0.0034	0.0728	0.3699
Schistosoma mansoni	steroid hormone receptor ad4bp	0.0012	0.0027	0.0137
Trypanosoma brucei	calpain-like protein, putative	0.0111	0.3238	1
Echinococcus granulosus	hepatocyte nuclear factor 4 alpha	0.0012	0.0027	0.003
Schistosoma mansoni	hypothetical protein	0.0027	0.0507	0.2573
Echinococcus granulosus	protein quaking	0.0027	0.0507	0.0567
Echinococcus granulosus	Basic leucine zipper bZIP transcription	0.0072	0.1969	0.2204
Schistosoma mansoni	tar DNA-binding protein	0.0064	0.1706	0.8665
Echinococcus multilocularis	thyroid hormone receptor alpha	0.0012	0.0027	0.003
Entamoeba histolytica	hypothetical protein	0.0072	0.1969	1
Echinococcus granulosus	hypothetical protein	0.0027	0.0507	0.0567
Loa Loa (eye worm)	hypothetical protein	0.0018	0.0201	0.0174
Trypanosoma brucei	calpain, putative	0.0111	0.3238	1
Schistosoma mansoni	Tr4/Tr2 (homologue)	0.0012	0.0027	0.0137
Schistosoma mansoni	nuclear hormone receptor	0.0012	0.0027	0.0137
Plasmodium vivax	flap endonuclease 1, putative	0.0026	0.0469	1
Echinococcus granulosus	FTZ F1 alpha	0.0012	0.0027	0.003
Mycobacterium leprae	PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE)	0.0023	0.0394	0.5
Trypanosoma brucei	calpain-like cysteine peptidase, putative	0.0111	0.3238	1
Loa Loa (eye worm)	RNA recognition domain-containing protein domain-containing protein	0.0064	0.1706	0.1684
Echinococcus granulosus	FTZ F1 nuclear receptor protein	0.0012	0.0027	0.003
Plasmodium falciparum	ataxin-2 like protein, putative	0.0025	0.0456	0.9501
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.0012	0.0027	0.003
Echinococcus multilocularis	protein quaking	0.0027	0.0507	0.0567
Echinococcus multilocularis	diuretic hormone 44 receptor GPRdih2	0.0016	0.0138	0.0154
Echinococcus multilocularis	FTZ F1 alpha	0.0012	0.0027	0.003
Loa Loa (eye worm)	TAR-binding protein	0.0064	0.1706	0.1684
Giardia lamblia	Flap structure-specific endonuclease	0.0026	0.0469	0.5
Echinococcus multilocularis	tar DNA binding protein	0.0064	0.1706	0.191
Mycobacterium ulcerans	acyl-CoA synthetase	0.0023	0.0394	1
Schistosoma mansoni	hypothetical protein	0.0072	0.1969	1
Echinococcus granulosus	Nuclear hormone receptor family member nhr 41	0.0012	0.0027	0.003
Schistosoma mansoni	retinoid-x-receptor (RXR)	0.0012	0.0027	0.0137
Mycobacterium ulcerans	fatty-acid-CoA ligase	0.0023	0.0394	1
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0055	0.1429	0.16
Trypanosoma cruzi	cysteine peptidase, Clan CA, family C2, putative	0.0111	0.3238	1
Trypanosoma brucei	cysteine peptidase, Clan CA, family C2, putative	0.0111	0.3238	1
Echinococcus granulosus	flap endonuclease 1	0.0026	0.0469	0.0525
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0055	0.1429	0.7257

Activities

Activity type	Activity value	Assay description	Source	Reference
Potency (functional)	5.6234 uM	PubChem BioAssay. qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory)	ChEMBL.	No reference
Potency (functional)	= 15.8489 um	PUBCHEM_BIOASSAY: qHTS Assay for Enhancers of SMN2 Splice Variant Expression. (Class of assay: confirmatory)	ChEMBL.	No reference
Potency (functional)	16.3601 uM	PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648]	ChEMBL.	No reference
Potency (functional)	= 19.9526 um	PUBCHEM_BIOASSAY: qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory)	ChEMBL.	No reference
Potency (functional)	= 31.6228 um	PUBCHEM_BIOASSAY: qHTS Assay for Modulators of Lamin A Splicing. (Class of assay: confirmatory)	ChEMBL.	No reference
Potency (functional)	= 39.8107 um	PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of HSD17B4, hydroxysteroid (17-beta) dehydrogenase 4. (Class of assay: confirmatory)	ChEMBL.	No reference
Potency (functional)	= 89.1251 um	PUBCHEM_BIOASSAY: qHTS Assay for the Inhibitors of Schistosoma Mansoni Peroxiredoxins. (Class of assay: confirmatory) [Related pubchem assays: 1011 (Confirmation Concentration-Response Assay for Inhibitors of the Schistosoma mansoni Redox Cascade ), 448 (Schistosoma Mansoni Peroxiredoxins (Prx2) and thioredoxin glutathione reductase (TGR) coupled assay)]	ChEMBL.	No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL1429544

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 1310865