Detailed information for compound 1334867

Basic information

Technical information
  • TDR Targets ID: 1334867
  • Name: N-(3-chloro-4-methylphenyl)-2-(3-furan-2-yl-6 -oxopyridazin-1-yl)acetamide
  • MW: 343.764 | Formula: C17H14ClN3O3
  • H donors: 1 H acceptors: 2 LogP: 2.74 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(Cn1nc(ccc1=O)c1ccco1)Nc1ccc(c(c1)Cl)C
  • InChi: 1S/C17H14ClN3O3/c1-11-4-5-12(9-13(11)18)19-16(22)10-21-17(23)7-6-14(20-21)15-3-2-8-24-15/h2-9H,10H2,1H3,(H,19,22)
  • InChiKey: AIUYQJHNJAYHJJ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • N-(3-chloro-4-methyl-phenyl)-2-[3-(2-furyl)-6-oxo-pyridazin-1-yl]acetamide
  • N-(3-chloro-4-methylphenyl)-2-[3-(2-furyl)-6-oxo-1-pyridazinyl]acetamide
  • N-(3-chloro-4-methyl-phenyl)-2-[3-(2-furyl)-6-keto-pyridazin-1-yl]acetamide
  • N-(3-chloro-4-methyl-phenyl)-2-(3-furan-2-yl-6-oxo-pyridazin-1-yl)ethanamide
  • STK290873
  • ZINC05387957

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens glucagon-like peptide 1 receptor Starlite/ChEMBL No references
Equus caballus Ferritin light chain Starlite/ChEMBL No references
Schistosoma mansoni Thioredoxin glutathione reductase Starlite/ChEMBL No references
Homo sapiens euchromatic histone-lysine N-methyltransferase 2 Starlite/ChEMBL No references
Homo sapiens polymerase (DNA directed), beta Starlite/ChEMBL No references
Escherichia coli penicillin-binding protein Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Toxoplasma gondii thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Leishmania mexicana mitochondrial DNA polymerase beta Get druggable targets OG5_130965 All targets in OG5_130965
Plasmodium yoelii glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative Get druggable targets OG5_130965 All targets in OG5_130965
Neospora caninum MGC84926 protein, related Get druggable targets OG5_126785 All targets in OG5_126785
Cryptosporidium parvum thioredoxin reductase 1 Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium yoelii thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Trypanosoma brucei gambiense trypanothione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Trypanosoma brucei trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Mycobacterium tuberculosis Possible penicillin-binding protein Get druggable targets OG5_149948 All targets in OG5_149948
Candida albicans similar to S. cerevisiae GLR1 (YPL091W) glutathione oxidoreductase Get druggable targets OG5_126785 All targets in OG5_126785
Leishmania mexicana trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Leishmania major trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Leishmania braziliensis mitochondrial DNA polymerase beta Get druggable targets OG5_130965 All targets in OG5_130965
Leishmania donovani trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Brugia malayi glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Trypanosoma congolense trypanothione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Leishmania infantum mitochondrial DNA polymerase beta Get druggable targets OG5_130965 All targets in OG5_130965
Neospora caninum Glutathione reductase, related Get druggable targets OG5_126785 All targets in OG5_126785
Leishmania major mitochondrial DNA polymerase beta Get druggable targets OG5_130965 All targets in OG5_130965
Cryptosporidium hominis thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Leishmania braziliensis trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium vivax thioredoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium falciparum glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Trypanosoma brucei gambiense mitochondrial DNA polymerase beta Get druggable targets OG5_130965 All targets in OG5_130965
Loa Loa (eye worm) glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Onchocerca volvulus Get druggable targets OG5_131470 All targets in OG5_131470
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative Get druggable targets OG5_130965 All targets in OG5_130965
Leishmania infantum trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Candida albicans similar to S. cerevisiae GLR1 (YPL091W) glutathione oxidoreductase Get druggable targets OG5_126785 All targets in OG5_126785
Echinococcus multilocularis thioredoxin glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Theileria parva thioredoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium vivax glutathione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium berghei glutathione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Echinococcus granulosus thioredoxin glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Loa Loa (eye worm) thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium knowlesi glutathione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Loa Loa (eye worm) pre-SET domain-containing protein family protein Get druggable targets OG5_131470 All targets in OG5_131470
Schistosoma japonicum ko:K00384 thioredoxin reductase (NADPH) [EC1.8.1.9], putative Get druggable targets OG5_126785 All targets in OG5_126785
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr Get druggable targets OG5_126785 All targets in OG5_126785
Trypanosoma congolense mitochondrial DNA polymerase beta, putative Get druggable targets OG5_130965 All targets in OG5_130965
Babesia bovis thiodoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Mycobacterium tuberculosis Conserved hypothetical protein Get druggable targets OG5_130965 All targets in OG5_130965
Leishmania donovani mitochondrial DNA polymerase beta Get druggable targets OG5_130965 All targets in OG5_130965
Plasmodium knowlesi thioredoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Brugia malayi Thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Brugia malayi Pre-SET motif family protein Get druggable targets OG5_131470 All targets in OG5_131470
Mycobacterium ulcerans hypothetical protein Get druggable targets OG5_130965 All targets in OG5_130965
Trypanosoma brucei mitochondrial DNA polymerase beta Get druggable targets OG5_130965 All targets in OG5_130965
Plasmodium berghei thioredoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Trichomonas vaginalis set domain proteins, putative Get druggable targets OG5_131470 All targets in OG5_131470
Plasmodium falciparum thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Trypanosoma cruzi trypanothione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Echinococcus multilocularis expressed protein Ferritin light chain   175 aa 146 aa 30.1 %
Plasmodium berghei dihydrolipoyl dehydrogenase, apicoplast, putative Thioredoxin glutathione reductase   598 aa 538 aa 25.3 %
Onchocerca volvulus Thioredoxin glutathione reductase   598 aa 533 aa 50.8 %
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative polymerase (DNA directed), beta 335 aa 303 aa 32.3 %
Schistosoma mansoni ferritin Ferritin light chain   175 aa 171 aa 44.4 %
Neospora caninum Dihydrolipoyl dehydrogenase (EC 1.8.1.4), related Thioredoxin glutathione reductase   598 aa 512 aa 28.3 %
Schistosoma japonicum Ferritin, putative Ferritin light chain   175 aa 144 aa 24.3 %
Schistosoma mansoni apoferritin-2 Ferritin light chain   175 aa 146 aa 28.8 %
Schistosoma mansoni ferritin Ferritin light chain   175 aa 171 aa 43.9 %
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative Thioredoxin glutathione reductase   598 aa 521 aa 21.5 %
Toxoplasma gondii NADPH-glutathione reductase Thioredoxin glutathione reductase   598 aa 555 aa 33.5 %
Plasmodium knowlesi dihydrolipoyl dehydrogenase, apicoplast, putative Thioredoxin glutathione reductase   598 aa 518 aa 22.0 %
Loa Loa (eye worm) pigment dispersing factor receptor c glucagon-like peptide 1 receptor 463 aa 388 aa 25.8 %
Schistosoma mansoni apoferritin-2 Ferritin light chain   175 aa 142 aa 29.6 %
Echinococcus granulosus expressed protein Ferritin light chain   175 aa 146 aa 28.8 %
Plasmodium yoelii dihydrolipoamide dehydrogenase Thioredoxin glutathione reductase   598 aa 537 aa 24.2 %
Neospora caninum hypothetical protein Thioredoxin glutathione reductase   598 aa 485 aa 30.5 %
Neospora caninum glutathione reductase, putative Thioredoxin glutathione reductase   598 aa 532 aa 34.6 %
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast Thioredoxin glutathione reductase   598 aa 513 aa 25.0 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Plasmodium falciparum bifunctional dihydrofolate reductase-thymidylate synthase 0.0387 0.3604 1
Schistosoma mansoni dihydrofolate reductase 0.1012 1 1
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0116 0.083 0.0747
Brugia malayi Pre-SET motif family protein 0.0251 0.2216 0.2205
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0116 0.083 0.0747
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.006 0.0261 0.0247
Mycobacterium ulcerans hypothetical protein 0.0192 0.161 0.1534
Loa Loa (eye worm) pigment dispersing factor receptor c 0.006 0.0261 0.0247
Mycobacterium tuberculosis Probable oxidoreductase 0.0116 0.083 0.0747
Plasmodium vivax glutathione reductase, putative 0.0046 0.0112 0.0274
Plasmodium vivax hypothetical protein, conserved 0.0043 0.009 0.0212
Onchocerca volvulus 0.0043 0.009 0.0297
Loa Loa (eye worm) hypothetical protein 0.0041 0.0066 0.0052
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0104 0.0711 0.0627
Loa Loa (eye worm) hypothetical protein 0.0043 0.009 0.0076
Mycobacterium ulcerans dihydrofolate reductase DfrA 0.1012 1 1
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0104 0.0711 0.0627
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0278 0.2486 0.2418
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0043 0.009 0.0076
Echinococcus multilocularis beta LACTamase domain containing family member 0.0043 0.009 0.0076
Leishmania major pteridine reductase 1 0.0587 0.5644 1
Loa Loa (eye worm) glutathione reductase 0.0046 0.0112 0.0099
Mycobacterium tuberculosis Probable dehydrogenase 0.0104 0.0711 0.0627
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0043 0.009 0.0076
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0104 0.0711 0.0627
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0116 0.083 0.0747
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0104 0.0711 0.0627
Leishmania major trypanothione reductase 0.0046 0.0112 0.0041
Toxoplasma gondii bifunctional dihydrofolate reductase-thymidylate synthase 0.0387 0.3604 1
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0365 0.3375 0.9349
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0173 0.141 0.2412
Echinococcus granulosus histone lysine methyltransferase setb 0.0036 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0043 0.009 0.0076
Loa Loa (eye worm) hypothetical protein 0.0043 0.009 0.0076
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase 0.0387 0.3604 1
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0173 0.141 0.2378
Toxoplasma gondii thioredoxin reductase 0.0046 0.0112 0.0274
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0365 0.3375 0.6
Brugia malayi Thioredoxin reductase 0.0046 0.0112 0.0099
Echinococcus granulosus beta LACTamase domain containing family member 0.0043 0.009 0.009
Trypanosoma brucei pteridine reductase 1 0.0579 0.5566 1
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0051 0.0169 0.0227
Echinococcus granulosus dihydrofolate reductase 0.1012 1 1
Brugia malayi Calcitonin receptor-like protein seb-1 0.006 0.0261 0.0247
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0104 0.0711 0.0627
Mycobacterium tuberculosis Probable reductase 0.0104 0.0711 0.0627
Toxoplasma gondii ABC1 family protein 0.0043 0.009 0.0212
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0051 0.0169 0.0227
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0043 0.009 0.0076
Mycobacterium tuberculosis Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) 0.1012 1 1
Loa Loa (eye worm) hypothetical protein 0.0043 0.009 0.0076
Brugia malayi beta-lactamase family protein 0.0043 0.009 0.0076
Loa Loa (eye worm) thioredoxin reductase 0.0046 0.0112 0.0099
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0173 0.141 0.3758
Onchocerca volvulus 0.0286 0.2571 1
Onchocerca volvulus 0.0043 0.009 0.0297
Brugia malayi beta-lactamase 0.0043 0.009 0.0076
Trichomonas vaginalis set domain proteins, putative 0.0286 0.2571 1
Echinococcus granulosus thioredoxin glutathione reductase 0.0046 0.0118 0.0118
Mycobacterium leprae DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) 0.1012 1 1
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0051 0.0169 0.0146
Brugia malayi latrophilin 2 splice variant baaae 0.0041 0.0066 0.0052
Loa Loa (eye worm) hypothetical protein 0.0043 0.009 0.0076
Brugia malayi beta-lactamase family protein 0.0043 0.009 0.0076
Chlamydia trachomatis dihydrofolate reductase 0.1012 1 0.5
Schistosoma mansoni hypothetical protein 0.0041 0.0066 0.0052
Brugia malayi glutathione reductase 0.0046 0.0112 0.0099
Plasmodium vivax thioredoxin reductase, putative 0.0046 0.0112 0.0274
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0043 0.009 0.0076
Echinococcus multilocularis thioredoxin glutathione reductase 0.0046 0.0118 0.0105
Toxoplasma gondii hypothetical protein 0.0059 0.0247 0.0649
Trypanosoma brucei trypanothione reductase 0.0046 0.0112 0.0041
Leishmania major dihydrofolate reductase-thymidylate synthase 0.0387 0.3604 0.6327
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0051 0.0169 0.0227
Trypanosoma brucei dihydrofolate reductase-thymidylate synthase 0.0387 0.3604 0.6418
Brugia malayi Dihydrofolate reductase 0.1012 1 1
Echinococcus multilocularis dihydrofolate reductase 0.1012 1 1
Loa Loa (eye worm) beta-lactamase 0.0043 0.009 0.0076
Leishmania major mitochondrial DNA polymerase beta 0.0365 0.3375 0.5915
Plasmodium vivax bifunctional dihydrofolate reductase-thymidylate synthase, putative 0.0387 0.3604 1
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0046 0.0112 0.0023
Loa Loa (eye worm) dihydrofolate reductase 0.1012 1 1
Loa Loa (eye worm) hypothetical protein 0.0043 0.009 0.0076
Loa Loa (eye worm) hypothetical protein 0.006 0.0261 0.0247
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0251 0.2216 0.2205
Trypanosoma cruzi trypanothione reductase, putative 0.0046 0.0112 0.0064
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0365 0.3375 0.9349
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0062 0.0284 0.0554
Onchocerca volvulus 0.0043 0.009 0.0297
Mycobacterium tuberculosis Conserved hypothetical protein 0.0192 0.161 0.1534

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 5.0119 uM PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 6.3096 um PUBCHEM_BIOASSAY: qHTS Assay for the Inhibitors of Schistosoma Mansoni Peroxiredoxins. (Class of assay: confirmatory) [Related pubchem assays: 1011 (Confirmation Concentration-Response Assay for Inhibitors of the Schistosoma mansoni Redox Cascade ), 448 (Schistosoma Mansoni Peroxiredoxins (Prx2) and thioredoxin glutathione reductase (TGR) coupled assay)] ChEMBL. No reference
Potency (functional) = 7.9433 um PUBCHEM_BIOASSAY: qHTS Inhibitors of AmpC Beta-Lactamase (assay with detergent). (Class of assay: confirmatory) [Related pubchem assays: 1002 (Confirmation Concentration-Response Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent)), 585 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay without detergent) - a screen old NIH MLSMR collection), 584 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay with detergent) - a screen of the old NIH MLSMR collection), 1003 (Confirmation Cuvette-Based Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent))] ChEMBL. No reference
Potency (binding) = 8.9125 um PUBCHEM_BIOASSAY: qHTS Assay for Identification of Novel General Anesthetics. In this assay, a GABAergic mimetic model system, apoferritin and a profluorescent 1-aminoanthracene ligand (1-AMA), was used to construct a competitive binding assay for identification of novel general anesthetics (Class of assay: confirmatory) [Related pubchem assays: 2385 (Probe Development Summary for Identification of Novel General Anesthetics), 2323 (Validation apoferritin assay run on SigmaAldrich LOPAC1280 collection)] ChEMBL. No reference
Potency (functional) = 10 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of DNA Polymerase Beta. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 11.2202 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404] ChEMBL. No reference
Potency (functional) 11.6891 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 28.1838 uM PUBCHEM_BIOASSAY: Confirmation Assay for Identification of Novel General Anesthetics. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2323, AID2385, AID485281] ChEMBL. No reference
Potency (binding) 28.1838 uM PubChem BioAssay. qHTS Assay for Inhibitors of MBNL1-poly(CUG) RNA binding. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 39.8107 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Mammalian Selenoprotein Thioredoxin Reductase 1 (TrxR1): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488771] ChEMBL. No reference
Potency (functional) = 50.1187 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Bacillus subtilis Sfp phosphopantetheinyl transferase (PPTase). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 50.1187 uM PubChem BioAssay. qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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