Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.078 | 0.1333 | 0.1333 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.078 | 0.1333 | 0.1158 |
Loa Loa (eye worm) | hypothetical protein | 0.0278 | 0.0198 | 0.0198 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.078 | 0.1333 | 0.1158 |
Trypanosoma cruzi | UDP-galactopyranose mutase | 0.0278 | 0.0198 | 0.5 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.078 | 0.1333 | 0.1483 |
Brugia malayi | Carboxylesterase family protein | 0.4618 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.4618 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.078 | 0.1333 | 0.1158 |
Chlamydia trachomatis | protoporphyrinogen oxidase | 0.0278 | 0.0198 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0278 | 0.0198 | 0.0198 |
Loa Loa (eye worm) | hypothetical protein | 0.0278 | 0.0198 | 0.0198 |
Mycobacterium ulcerans | flavin-containing monoamine oxidase AofH | 0.3944 | 0.8479 | 1 |
Leishmania major | UDP-galactopyranose mutase | 0.0278 | 0.0198 | 0.5 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.078 | 0.1333 | 0.1483 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.078 | 0.1333 | 0.1158 |
Plasmodium vivax | protoporphyrinogen oxidase, putative | 0.0278 | 0.0198 | 0.5 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.078 | 0.1333 | 0.1483 |
Mycobacterium ulcerans | flavin-containing monoamine oxidase AofH | 0.3944 | 0.8479 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.078 | 0.1333 | 0.1333 |
Onchocerca volvulus | 0.078 | 0.1333 | 1 | |
Echinococcus granulosus | neuroligin | 0.078 | 0.1333 | 0.1158 |
Plasmodium vivax | hypothetical protein, conserved | 0.0278 | 0.0198 | 0.5 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.078 | 0.1333 | 0.1158 |
Trypanosoma cruzi | UDP-galactopyranose mutase | 0.0278 | 0.0198 | 0.5 |
Echinococcus granulosus | acetylcholinesterase | 0.4618 | 1 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.078 | 0.1333 | 0.1333 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.4618 | 1 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.078 | 0.1333 | 0.1333 |
Onchocerca volvulus | 0.078 | 0.1333 | 1 | |
Brugia malayi | hypothetical protein | 0.078 | 0.1333 | 0.1158 |
Plasmodium vivax | lysine-specific histone demethylase 1, putative | 0.0278 | 0.0198 | 0.5 |
Echinococcus granulosus | BC026374 protein S09 family | 0.078 | 0.1333 | 0.1158 |
Echinococcus multilocularis | acetylcholinesterase | 0.4618 | 1 | 1 |
Schistosoma mansoni | gliotactin | 0.078 | 0.1333 | 0.1158 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.078 | 0.1333 | 0.1158 |
Brugia malayi | Amyloid A4 extracellular domain containing protein | 0.09 | 0.1603 | 0.1434 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.078 | 0.1333 | 0.137 |
Loa Loa (eye worm) | hypothetical protein | 0.078 | 0.1333 | 0.1333 |
Toxoplasma gondii | histone lysine-specific demethylase LSD1/BHC110/KDMA1A | 0.0278 | 0.0198 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.078 | 0.1333 | 0.1333 |
Loa Loa (eye worm) | hypothetical protein | 0.078 | 0.1333 | 0.1333 |
Schistosoma mansoni | alzheimer's disease beta-amyloid related | 0.0328 | 0.0312 | 0.0116 |
Mycobacterium tuberculosis | Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) | 0.3666 | 0.7852 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0381 | 0.0431 | 0.0431 |
Plasmodium falciparum | protoporphyrinogen oxidase | 0.0278 | 0.0198 | 0.5 |
Echinococcus multilocularis | carboxylesterase 5A | 0.4618 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0278 | 0.0198 | 0.0198 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.078 | 0.1333 | 0.1158 |
Echinococcus multilocularis | neuroligin | 0.078 | 0.1333 | 0.1158 |
Echinococcus granulosus | acetylcholinesterase | 0.4618 | 1 | 1 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.078 | 0.1333 | 0.1158 |
Loa Loa (eye worm) | hypothetical protein | 0.0709 | 0.1172 | 0.1172 |
Loa Loa (eye worm) | hypothetical protein | 0.078 | 0.1333 | 0.1333 |
Echinococcus multilocularis | acetylcholinesterase | 0.4618 | 1 | 1 |
Onchocerca volvulus | 0.078 | 0.1333 | 1 | |
Schistosoma mansoni | acetylcholinesterase | 0.078 | 0.1333 | 0.1158 |
Loa Loa (eye worm) | hypothetical protein | 0.0278 | 0.0198 | 0.0198 |
Loa Loa (eye worm) | hypothetical protein | 0.0278 | 0.0198 | 0.0198 |
Toxoplasma gondii | histone lysine-specific demethylase | 0.0278 | 0.0198 | 0.5 |
Plasmodium falciparum | lysine-specific histone demethylase 1, putative | 0.0278 | 0.0198 | 0.5 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.078 | 0.1333 | 0.1158 |
Loa Loa (eye worm) | hypothetical protein | 0.4618 | 1 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.078 | 0.1333 | 0.1158 |
Plasmodium vivax | hypothetical protein, conserved | 0.0278 | 0.0198 | 0.5 |
Echinococcus granulosus | carboxylesterase 5A | 0.4618 | 1 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.4618 | 1 | 1 |
Mycobacterium leprae | PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) | 0.0278 | 0.0198 | 0.5 |
Onchocerca volvulus | 0.078 | 0.1333 | 1 | |
Brugia malayi | Carboxylesterase family protein | 0.078 | 0.1333 | 0.1158 |
Loa Loa (eye worm) | hypothetical protein | 0.078 | 0.1333 | 0.1333 |
Brugia malayi | Carboxylesterase family protein | 0.078 | 0.1333 | 0.1158 |
Brugia malayi | Carboxylesterase family protein | 0.078 | 0.1333 | 0.1158 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.078 | 0.1333 | 0.1158 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.078 | 0.1333 | 0.5 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.078 | 0.1333 | 0.5 |
Loa Loa (eye worm) | carboxylesterase | 0.4618 | 1 | 1 |
Plasmodium falciparum | conserved Plasmodium protein, unknown function | 0.0278 | 0.0198 | 0.5 |
Onchocerca volvulus | 0.078 | 0.1333 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.