Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | slit 2 protein | 0.0023 | 0.5 | 0.5 |
Schistosoma mansoni | cell polarity protein | 0.0023 | 0.5 | 0.5 |
Brugia malayi | laminin alpha chain | 0.0023 | 0.5 | 0.5 |
Schistosoma mansoni | laminin gamma-3 chain | 0.0023 | 0.5 | 0.5 |
Schistosoma mansoni | chondroitin sulfate proteoglycan-related | 0.0023 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.5 | 0.5 |
Echinococcus multilocularis | neurogenic locus notch protein | 0.0023 | 0.5 | 0.5 |
Brugia malayi | Thrombospondin N-terminal -like domain containing protein | 0.0023 | 0.5 | 0.5 |
Brugia malayi | EGF-like domain containing protein | 0.0023 | 0.5 | 0.5 |
Echinococcus granulosus | neurogenic locus notch protein | 0.0023 | 0.5 | 0.5 |
Echinococcus granulosus | slit 2 protein | 0.0023 | 0.5 | 0.5 |
Schistosoma mansoni | slit | 0.0023 | 0.5 | 0.5 |
Loa Loa (eye worm) | abnormal epIthelia family member | 0.0023 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.5 | 0.5 |
Echinococcus multilocularis | pikachurin | 0.0023 | 0.5 | 0.5 |
Echinococcus granulosus | pikachurin | 0.0023 | 0.5 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.