Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) | 0.006 | 0.0298 | 0.0774 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0046 | 0.0207 | 0.0207 |
Trypanosoma brucei | trypanothione reductase | 0.0046 | 0.0207 | 0.0207 |
Trichomonas vaginalis | chromobox protein, putative | 0.0081 | 0.0444 | 0.2505 |
Brugia malayi | Importin beta-1 subunit | 0.0028 | 0.0083 | 0.0083 |
Brugia malayi | hypothetical protein | 0.0029 | 0.0091 | 0.0091 |
Echinococcus multilocularis | peptidase Clp (S14 family) | 0.006 | 0.0298 | 0.0298 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0035 | 0.0128 | 0.0128 |
Echinococcus multilocularis | phd:f box containing protein | 0.0026 | 0.007 | 0.007 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0548 | 0.3633 | 0.3633 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0035 | 0.0128 | 0.0128 |
Trypanosoma cruzi | JmjC domain, hydroxylase, putative | 0.0026 | 0.007 | 0.007 |
Brugia malayi | Bromodomain containing protein | 0.0034 | 0.0122 | 0.0122 |
Toxoplasma gondii | thioredoxin reductase | 0.0046 | 0.0207 | 0.404 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0018 | 0.0016 | 0.0016 |
Onchocerca volvulus | 0.0275 | 0.1773 | 1 | |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0026 | 0.007 | 0.0054 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0301 | 0.195 | 0.1937 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0128 | 0.0112 |
Echinococcus multilocularis | lysine specific demethylase 6a | 0.0026 | 0.007 | 0.007 |
Echinococcus multilocularis | chromobox protein 1 | 0.0081 | 0.0444 | 0.0444 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0091 | 0.0075 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0091 | 0.0512 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0122 | 0.0106 |
Echinococcus multilocularis | Jumonji, AT rich interactive domain 1B | 0.0026 | 0.007 | 0.007 |
Brugia malayi | Probable ClpP-like protease | 0.0091 | 0.0512 | 0.0512 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0548 | 0.3633 | 0.3633 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0282 | 0.1821 | 0.1808 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0048 | 0.0218 | 0.0218 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0018 | 0.0016 | 0.0016 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0029 | 0.0091 | 0.1771 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0045 | 0.0201 | 0.1132 |
Schistosoma mansoni | hypothetical protein | 0.0363 | 0.2371 | 0.2371 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0046 | 0.0207 | 0.0207 |
Brugia malayi | jmjC domain containing protein | 0.0026 | 0.007 | 0.007 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0023 | 0.0047 | 0.0264 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0117 | 0.0693 | 0.18 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0099 | 0.0564 | 0.0564 |
Schistosoma mansoni | peptidase Clp (S14 family) | 0.0091 | 0.0512 | 0.0512 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0029 | 0.0091 | 0.1771 |
Schistosoma mansoni | chromobox protein | 0.0081 | 0.0444 | 0.0444 |
Trichomonas vaginalis | importin beta-1, putative | 0.0023 | 0.0047 | 0.0264 |
Echinococcus multilocularis | geminin | 0.0363 | 0.2371 | 0.2371 |
Echinococcus multilocularis | jumonji domain containing 1A | 0.0026 | 0.007 | 0.007 |
Echinococcus multilocularis | JmjC domain containing protein 4 | 0.0026 | 0.007 | 0.007 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0046 | 0.0207 | 0.0191 |
Brugia malayi | follicle stimulating hormone receptor | 0.0282 | 0.1821 | 0.1821 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0071 | 0.0377 | 0.0377 |
Mycobacterium tuberculosis | Probable reductase | 0.0106 | 0.0612 | 0.1591 |
Schistosoma mansoni | phosphatidylserine receptor | 0.0026 | 0.007 | 0.007 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0026 | 0.007 | 0.0054 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0018 | 0.0016 | 0.0311 |
Brugia malayi | Isocitrate dehydrogenase | 0.0018 | 0.0016 | 0.0016 |
Trichomonas vaginalis | chromobox protein, putative | 0.0049 | 0.0224 | 0.1265 |
Loa Loa (eye worm) | hypothetical protein | 0.0091 | 0.0512 | 0.0497 |
Brugia malayi | Pre-SET motif family protein | 0.0242 | 0.1544 | 0.1544 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0242 | 0.1544 | 0.1531 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0201 | 0.0185 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0099 | 0.0564 | 0.0549 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0046 | 0.0207 | 0.0537 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0099 | 0.0564 | 0.0564 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.007 | 0.0054 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0071 | 0.0377 | 0.098 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0071 | 0.0377 | 0.0377 |
Loa Loa (eye worm) | hypothetical protein | 0.0327 | 0.2123 | 0.2111 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0018 | 0.0016 | 0.0016 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.0034 | 0.0122 | 0.0122 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0035 | 0.0128 | 0.0128 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0018 | 0.0016 | 0.0016 |
Schistosoma mansoni | protein phosphatase 2C | 0.0026 | 0.007 | 0.007 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0034 | 0.0122 | 0.2384 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0018 | 0.0016 | 0.0016 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0091 | 0.0512 | 0.133 |
Echinococcus multilocularis | peregrin | 0.0034 | 0.0122 | 0.0122 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0035 | 0.0128 | 0.2493 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0091 | 0.0512 | 1 |
Brugia malayi | glutathione reductase | 0.0046 | 0.0207 | 0.0207 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0018 | 0.0016 | 0.0016 |
Onchocerca volvulus | 0.0036 | 0.0134 | 0.007 | |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0029 | 0.0091 | 0.1771 |
Echinococcus granulosus | ATP dependent Clp protease proteolytic subunit | 0.0091 | 0.0512 | 0.0512 |
Giardia lamblia | PHD finger protein 15 | 0.0034 | 0.0122 | 1 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0046 | 0.0207 | 0.0207 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0018 | 0.0016 | 0.0016 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0029 | 0.0091 | 0.0091 |
Echinococcus granulosus | peregrin | 0.0034 | 0.0122 | 0.0122 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.0034 | 0.0122 | 0.0122 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0045 | 0.0201 | 0.1132 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0091 | 0.0512 | 1 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0035 | 0.0128 | 0.0128 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0083 | 0.0067 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0018 | 0.0016 | 0.0311 |
Loa Loa (eye worm) | hypothetical protein | 0.1472 | 0.9948 | 0.9948 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent Clp protease proteolytic subunit | 0.0091 | 0.0512 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0122 | 0.0122 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0029 | 0.0091 | 0.0091 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) | 0.006 | 0.0298 | 0.0516 |
Schistosoma mansoni | ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related | 0.0026 | 0.007 | 0.007 |
Trichomonas vaginalis | set domain proteins, putative | 0.0275 | 0.1773 | 1 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0071 | 0.0377 | 0.7366 |
Toxoplasma gondii | histone lysine demethylase JMJC1/KDM5D/JARID1D | 0.0026 | 0.007 | 0.1369 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0046 | 0.0207 | 0.404 |
Schistosoma mansoni | jumonji domain containing protein | 0.0026 | 0.007 | 0.007 |
Echinococcus granulosus | neuropeptide s receptor | 0.0548 | 0.3633 | 0.3633 |
Brugia malayi | chromobox protein homolog 3 | 0.0045 | 0.0201 | 0.0201 |
Echinococcus multilocularis | ATP dependent Clp protease proteolytic subunit | 0.0091 | 0.0512 | 0.0512 |
Brugia malayi | jmjC domain containing protein | 0.0099 | 0.0564 | 0.0564 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0047 | 0.0213 | 0.0213 |
Mycobacterium ulcerans | hypothetical protein | 0.0579 | 0.3847 | 1 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) | 0.0091 | 0.0512 | 0.1088 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0032 | 0.011 | 0.0621 |
Mycobacterium leprae | Conserved hypothetical protein | 0.0579 | 0.3847 | 1 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.0028 | 0.0083 | 0.1628 |
Echinococcus granulosus | geminin | 0.0363 | 0.2371 | 0.2371 |
Echinococcus multilocularis | snurportin 1 | 0.0301 | 0.195 | 0.195 |
Plasmodium vivax | glutathione reductase, putative | 0.0046 | 0.0207 | 0.404 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0099 | 0.0564 | 0.0564 |
Plasmodium falciparum | importin beta, putative | 0.0028 | 0.0083 | 0.1628 |
Echinococcus granulosus | lysine specific demethylase 6a | 0.0026 | 0.007 | 0.007 |
Onchocerca volvulus | 0.0048 | 0.0218 | 0.0583 | |
Schistosoma mansoni | importin beta-1 | 0.0028 | 0.0083 | 0.0083 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0106 | 0.0612 | 0.1591 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0134 | 0.0118 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0033 | 0.0119 | 0.0119 |
Brugia malayi | PHD-finger family protein | 0.0034 | 0.0122 | 0.0122 |
Plasmodium vivax | SET domain protein, putative | 0.0035 | 0.0128 | 0.2493 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.007 | 0.0369 | 0.0353 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0031 | 0.0104 | 0.2041 |
Echinococcus granulosus | chromobox protein 1 | 0.0081 | 0.0444 | 0.0444 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0071 | 0.0377 | 0.098 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0071 | 0.0377 | 0.098 |
Trypanosoma cruzi | JmjC domain, hydroxylase, putative | 0.0026 | 0.007 | 0.007 |
Brugia malayi | jmjC domain containing protein | 0.0169 | 0.1043 | 0.1043 |
Schistosoma mansoni | hypothetical protein | 0.0301 | 0.195 | 0.195 |
Schistosoma mansoni | phd/f-box containing protein | 0.0026 | 0.007 | 0.007 |
Echinococcus granulosus | JmjC domain containing protein 4 | 0.0026 | 0.007 | 0.007 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0091 | 0.0512 | 1 |
Trypanosoma cruzi | importin beta-1 subunit, putative | 0.0023 | 0.0047 | 0.0047 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0031 | 0.0104 | 0.2041 |
Echinococcus granulosus | jumonji domain containing 1A | 0.0026 | 0.007 | 0.007 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0031 | 0.0104 | 0.2041 |
Brugia malayi | hypothetical protein | 0.0019 | 0.002 | 0.002 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0117 | 0.0693 | 0.1572 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0023 | 0.0047 | 0.0264 |
Plasmodium falciparum | phd finger protein, putative | 0.0034 | 0.0122 | 0.2384 |
Plasmodium vivax | JmjC domain containing protein | 0.0026 | 0.007 | 0.1369 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0029 | 0.0091 | 0.1771 |
Brugia malayi | Thioredoxin reductase | 0.0046 | 0.0207 | 0.0207 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0106 | 0.0612 | 0.1591 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0018 | 0.0016 | 0.0016 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0032 | 0.011 | 0.0621 |
Trypanosoma brucei | JmjC domain, hydroxylase, putative | 0.0026 | 0.007 | 0.007 |
Loa Loa (eye worm) | hypothetical protein | 0.1472 | 0.9948 | 0.9948 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0106 | 0.0612 | 0.1591 |
Leishmania major | importin beta-1 subunit, putative | 0.0023 | 0.0047 | 0.0047 |
Plasmodium vivax | hypothetical protein, conserved | 0.0034 | 0.0122 | 0.2384 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0071 | 0.0377 | 0.0377 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0117 | 0.0693 | 0.18 |
Trichomonas vaginalis | chromobox protein, putative | 0.0049 | 0.0224 | 0.1265 |
Mycobacterium tuberculosis | Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) | 0.0018 | 0.0016 | 0.0041 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0169 | 0.1043 | 0.1043 |
Schistosoma mansoni | hypothetical protein | 0.0363 | 0.2371 | 0.2371 |
Echinococcus granulosus | importin subunit beta 1 | 0.0028 | 0.0083 | 0.0083 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0034 | 0.0122 | 0.2384 |
Leishmania major | hypothetical protein, conserved | 0.0029 | 0.0091 | 0.0091 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0099 | 0.0564 | 0.0564 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.007 | 0.0054 |
Toxoplasma gondii | histone lysine demethylase JMJD6a | 0.0026 | 0.007 | 0.1369 |
Plasmodium vivax | isocitrate dehydrogenase [NADP], mitochondrial, putative | 0.0018 | 0.0016 | 0.0311 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0081 | 0.0444 | 0.0429 |
Echinococcus granulosus | phd:f box containing protein | 0.0026 | 0.007 | 0.007 |
Plasmodium falciparum | isocitrate dehydrogenase [NADP], mitochondrial | 0.0018 | 0.0016 | 0.0311 |
Brugia malayi | Pre-SET motif family protein | 0.0035 | 0.0128 | 0.0128 |
Echinococcus granulosus | chromobox protein 1 | 0.0081 | 0.0444 | 0.0444 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0579 | 0.3847 | 1 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.0034 | 0.0122 | 0.0122 |
Echinococcus granulosus | jumonji domain containing protein | 0.0047 | 0.0213 | 0.0213 |
Brugia malayi | Heterochromatin protein 1 | 0.0081 | 0.0444 | 0.0444 |
Echinococcus granulosus | smoothened | 0.0334 | 0.217 | 0.217 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0018 | 0.0016 | 0.0016 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0091 | 0.0512 | 1 |
Schistosoma mansoni | chromobox protein | 0.0081 | 0.0444 | 0.0444 |
Plasmodium falciparum | JmjC domain-containing protein, putative | 0.0026 | 0.007 | 0.1369 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0071 | 0.0377 | 0.098 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0106 | 0.0612 | 0.1356 |
Brugia malayi | jmjC domain containing protein | 0.0026 | 0.007 | 0.007 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0106 | 0.0612 | 0.1591 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0071 | 0.0377 | 0.0377 |
Leishmania major | trypanothione reductase | 0.0046 | 0.0207 | 0.0207 |
Plasmodium falciparum | glutathione reductase | 0.0046 | 0.0207 | 0.404 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0091 | 0.0512 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0392 | 0.0377 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) | 0.006 | 0.0298 | 0.0774 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0169 | 0.1043 | 0.1043 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0035 | 0.0128 | 0.0128 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0018 | 0.0016 | 0.0016 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0026 | 0.007 | 0.0054 |
Echinococcus multilocularis | chromobox protein 1 | 0.0081 | 0.0444 | 0.0444 |
Echinococcus granulosus | peptidase Clp S14 family | 0.006 | 0.0298 | 0.0298 |
Echinococcus granulosus | Jumonji AT rich interactive domain 1B | 0.0026 | 0.007 | 0.007 |
Brugia malayi | jmjC domain containing protein | 0.0026 | 0.007 | 0.007 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0018 | 0.0016 | 0.0016 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0106 | 0.0612 | 0.1591 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0035 | 0.0128 | 0.0128 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0091 | 0.0512 | 1 |
Echinococcus multilocularis | smoothened | 0.0334 | 0.217 | 0.217 |
Brugia malayi | jmjC domain containing protein | 0.0026 | 0.007 | 0.007 |
Brugia malayi | RNA, U transporter 1 | 0.008 | 0.0439 | 0.0439 |
Loa Loa (eye worm) | glutathione reductase | 0.0046 | 0.0207 | 0.0191 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0049 | 0.0224 | 0.0619 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0028 | 0.0083 | 0.0083 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0045 | 0.0201 | 0.0477 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0034 | 0.0122 | 0.0106 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0117 | 0.0693 | 0.18 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0029 | 0.0091 | 0.0091 |
Echinococcus multilocularis | importin subunit beta 1 | 0.0028 | 0.0083 | 0.0083 |
Leishmania major | hypothetical protein, conserved | 0.0026 | 0.007 | 0.007 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0091 | 0.0512 | 0.133 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0548 | 0.3633 | 0.3633 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0018 | 0.0016 | 0.0016 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0071 | 0.0377 | 0.0377 |
Echinococcus granulosus | snurportin 1 | 0.0301 | 0.195 | 0.195 |
Plasmodium vivax | importin-beta 2, putative | 0.0028 | 0.0083 | 0.1628 |
Schistosoma mansoni | jumonji domain containing protein | 0.0146 | 0.0887 | 0.0887 |
Brugia malayi | isocitrate dehydrogenase | 0.0018 | 0.0016 | 0.0016 |
Trichomonas vaginalis | chromobox protein, putative | 0.0081 | 0.0444 | 0.2505 |
Plasmodium falciparum | thioredoxin reductase | 0.0046 | 0.0207 | 0.404 |
Toxoplasma gondii | hypothetical protein | 0.0031 | 0.0104 | 0.2041 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0028 | 0.0083 | 0.0083 |
Species name | Source | Reference | Is orphan |
---|---|---|---|
Mus musculus | ChEMBL23 | 21382720 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.