Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | expressed protein | 0.0265 | 0.1461 | 0.1751 |
Loa Loa (eye worm) | hypothetical protein | 0.0265 | 0.1461 | 0.1461 |
Echinococcus multilocularis | regulator of G protein signaling | 0.0265 | 0.1461 | 0.1751 |
Schistosoma mansoni | regulator of G protein signaling | 0.0265 | 0.1461 | 0.1461 |
Echinococcus granulosus | Squalene phytoene synthase | 0.0076 | 0.0282 | 0.0338 |
Entamoeba histolytica | hypothetical protein | 0.0265 | 0.1461 | 1 |
Echinococcus multilocularis | regulator of G protein signaling 3 | 0.0265 | 0.1461 | 0.1751 |
Trypanosoma cruzi | phytoene synthase, putative | 0.0076 | 0.0282 | 0.2125 |
Brugia malayi | Plexin repeat family protein | 0.0034 | 0.0018 | 0.0018 |
Echinococcus multilocularis | G protein coupled receptor kinase 1 | 0.0988 | 0.5968 | 0.7149 |
Echinococcus multilocularis | axis inhibition protein axin | 0.0265 | 0.1461 | 0.1751 |
Trypanosoma cruzi | squalene synthase, putative | 0.0244 | 0.1328 | 1 |
Schistosoma mansoni | regulator of G protein signaling | 0.0265 | 0.1461 | 0.1461 |
Echinococcus granulosus | A kinase anchor protein 10 mitochondrial | 0.0265 | 0.1461 | 0.1751 |
Mycobacterium ulcerans | phytoene synthase, CrtB | 0.0076 | 0.0282 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.0282 | 0.0282 |
Trypanosoma brucei | squalene synthase, putative | 0.0244 | 0.1328 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0265 | 0.1461 | 0.1461 |
Brugia malayi | regulator of G-protein signaling egl-10 | 0.0265 | 0.1461 | 0.1461 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0265 | 0.1461 | 1 |
Loa Loa (eye worm) | PXA domain-containing protein | 0.0265 | 0.1461 | 0.1461 |
Loa Loa (eye worm) | hypothetical protein | 0.0265 | 0.1461 | 0.1461 |
Brugia malayi | Regulator of G protein signaling domain containing protein | 0.0265 | 0.1461 | 0.1461 |
Brugia malayi | regulator of G-protein signaling rgs-7 | 0.0265 | 0.1461 | 0.1461 |
Echinococcus granulosus | regulator of G protein signaling 3 | 0.0265 | 0.1461 | 0.1751 |
Echinococcus granulosus | G protein coupled receptor kinase 1 | 0.0988 | 0.5968 | 0.7149 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0018 | 0.0018 |
Echinococcus granulosus | axis inhibition protein axin | 0.0265 | 0.1461 | 0.1751 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0265 | 0.1461 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0265 | 0.1461 | 1 |
Schistosoma mansoni | regulator of G protein signaling 3 rgs3 | 0.0265 | 0.1461 | 0.1461 |
Echinococcus granulosus | regulator of G protein signaling 3 | 0.0265 | 0.1461 | 0.1751 |
Echinococcus multilocularis | expressed protein | 0.0265 | 0.1461 | 0.1751 |
Loa Loa (eye worm) | AGC/GRK/BARK protein kinase | 0.1253 | 0.762 | 0.762 |
Schistosoma mansoni | regulator of G protein signaling 17 19 20 (rgs17 19 20) | 0.0265 | 0.1461 | 0.1461 |
Brugia malayi | PXA domain containing protein | 0.0265 | 0.1461 | 0.1461 |
Echinococcus multilocularis | axis inhibition protein axin | 0.0265 | 0.1461 | 0.1751 |
Echinococcus multilocularis | A kinase anchor protein 10, mitochondrial | 0.0265 | 0.1461 | 0.1751 |
Echinococcus multilocularis | regulator of G protein signaling 3 | 0.0265 | 0.1461 | 0.1751 |
Schistosoma mansoni | plexin | 0.0034 | 0.0018 | 0.0018 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0265 | 0.1461 | 1 |
Schistosoma mansoni | z-protein (S1r protein) | 0.0265 | 0.1461 | 0.1461 |
Leishmania major | hypothetical protein, conserved | 0.0076 | 0.0282 | 0.2125 |
Brugia malayi | plexin A | 0.004 | 0.0057 | 0.0057 |
Brugia malayi | hypothetical protein | 0.0265 | 0.1461 | 0.1461 |
Schistosoma mansoni | regulator of G protein signaling | 0.0265 | 0.1461 | 0.1461 |
Schistosoma mansoni | axis inhibition protein axin | 0.0265 | 0.1461 | 0.1461 |
Loa Loa (eye worm) | G protein signaling regulator EGL-10 | 0.0265 | 0.1461 | 0.1461 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.0265 | 0.1461 | 0.1751 |
Entamoeba histolytica | hypothetical protein | 0.0265 | 0.1461 | 1 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.0265 | 0.1461 | 0.1751 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0265 | 0.1461 | 1 |
Echinococcus multilocularis | beta adrenergic receptor kinase | 0.1253 | 0.762 | 0.9129 |
Entamoeba histolytica | hypothetical protein | 0.0265 | 0.1461 | 1 |
Loa Loa (eye worm) | G protein-coupled receptor kinase 1 | 0.137 | 0.8347 | 0.8347 |
Schistosoma mansoni | regulator of G protein signaling | 0.0265 | 0.1461 | 0.1461 |
Echinococcus multilocularis | Squalene phytoene synthase | 0.0076 | 0.0282 | 0.0338 |
Echinococcus granulosus | plexin a4 | 0.004 | 0.0057 | 0.0068 |
Brugia malayi | Probable G protein-coupled receptor kinase F19C6.1, putative | 0.137 | 0.8347 | 0.8347 |
Echinococcus granulosus | [G-protein-coupledreceptor] kinase | 0.137 | 0.8347 | 1 |
Echinococcus multilocularis | G protein coupled receptor kinase 6 | 0.137 | 0.8347 | 1 |
Loa Loa (eye worm) | AGC/GRK/GRK protein kinase | 0.137 | 0.8347 | 0.8347 |
Echinococcus granulosus | beta-adrenergic receptor kinase | 0.1253 | 0.762 | 0.9129 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0265 | 0.1461 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.1253 | 0.762 | 0.762 |
Loa Loa (eye worm) | hypothetical protein | 0.0265 | 0.1461 | 0.1461 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.0265 | 0.1461 | 0.1751 |
Loa Loa (eye worm) | RGS-3 protein | 0.0265 | 0.1461 | 0.1461 |
Brugia malayi | PXA domain containing protein | 0.0265 | 0.1461 | 0.1461 |
Echinococcus granulosus | Regulator of G protein signaling 20 | 0.0265 | 0.1461 | 0.1751 |
Trichomonas vaginalis | regulator of G protein signaling 5, rgs5, putative | 0.0265 | 0.1461 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0265 | 0.1461 | 0.1461 |
Trypanosoma cruzi | squalene synthase, putative | 0.0244 | 0.1328 | 1 |
Brugia malayi | A-kinase anchor protein 10, precursor | 0.0265 | 0.1461 | 0.1461 |
Schistosoma mansoni | regulator of G protein signaling | 0.0265 | 0.1461 | 0.1461 |
Echinococcus granulosus | axis inhibition protein axin | 0.0265 | 0.1461 | 0.1751 |
Schistosoma mansoni | axis inhibition protein axin | 0.0265 | 0.1461 | 0.1461 |
Loa Loa (eye worm) | plexin A | 0.004 | 0.0057 | 0.0057 |
Schistosoma mansoni | hypothetical protein | 0.0076 | 0.0282 | 0.0282 |
Leishmania major | squalene synthase, putative | 0.0244 | 0.1328 | 1 |
Schistosoma mansoni | regulator of G protein signaling 17 19 20 (rgs17 19 20) | 0.0265 | 0.1461 | 0.1461 |
Echinococcus multilocularis | plexin a4 | 0.004 | 0.0057 | 0.0068 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.0265 | 0.1461 | 0.1751 |
Onchocerca volvulus | NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 homolog | 0.0076 | 0.0282 | 1 |
Brugia malayi | hypothetical protein | 0.0265 | 0.1461 | 0.1461 |
Loa Loa (eye worm) | hypothetical protein | 0.0265 | 0.1461 | 0.1461 |
Schistosoma mansoni | serine/threonine protein kinase | 0.1253 | 0.762 | 0.762 |
Mycobacterium tuberculosis | Probable phytoene synthase PhyA | 0.0076 | 0.0282 | 0.5 |
Brugia malayi | Regulator of G protein signaling domain containing protein | 0.0265 | 0.1461 | 0.1461 |
Echinococcus multilocularis | Regulator of G protein signaling 20 | 0.0265 | 0.1461 | 0.1751 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.