Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | serine:threonine protein kinase haspin | 0.0481 | 0.9918 | 1 |
Brugia malayi | hypothetical protein | 0.0481 | 0.9918 | 1 |
Loa Loa (eye worm) | haspin protein kinase | 0.0481 | 0.9918 | 0.9918 |
Echinococcus granulosus | serine:threonine protein kinase haspin | 0.0481 | 0.9918 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0375 | 0.7243 | 1 |
Echinococcus granulosus | dual specificity | 0.0375 | 0.7243 | 0.7302 |
Brugia malayi | GSG2 | 0.0481 | 0.9918 | 1 |
Echinococcus multilocularis | dual specificity | 0.0375 | 0.7243 | 0.7302 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0375 | 0.7243 | 1 |
Loa Loa (eye worm) | CMGC/DYRK/DYRK2 protein kinase | 0.0375 | 0.7243 | 0.7243 |
Brugia malayi | Dual-specificity tyrosine-phosphorylation regulated kinase 2 | 0.0375 | 0.7243 | 0.7302 |
Echinococcus multilocularis | dual specificity | 0.0375 | 0.7243 | 0.7302 |
Schistosoma mansoni | hypothetical protein | 0.0481 | 0.9918 | 1 |
Toxoplasma gondii | cell-cycle-associated protein kinase DYRK2, putative | 0.0375 | 0.7243 | 0.5 |
Plasmodium falciparum | MO15-related protein kinase | 0.0086 | 0 | 0.5 |
Echinococcus granulosus | serine:threonine protein kinase haspin | 0.0481 | 0.9918 | 1 |
Giardia lamblia | Kinase, CMGC DYRK | 0.0375 | 0.7243 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.0375 | 0.7243 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0375 | 0.7243 | 0.7302 |
Echinococcus multilocularis | serine:threonine protein kinase haspin | 0.0481 | 0.9918 | 1 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0375 | 0.7243 | 1 |
Echinococcus granulosus | dual specificity | 0.0375 | 0.7243 | 0.7302 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0375 | 0.7243 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0375 | 0.7243 | 1 |
Echinococcus multilocularis | serine:threonine protein kinase haspin | 0.0481 | 0.9918 | 1 |
Echinococcus granulosus | dual specificity | 0.0375 | 0.7243 | 0.7302 |
Trypanosoma brucei | dual specificity tyrosine-phosphorylation-regulated kinase 2, putative | 0.0375 | 0.7243 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0375 | 0.7243 | 1 |
Trypanosoma cruzi | dual specificity tyrosine-phosphorylation-regulated kinase 2, putative | 0.0375 | 0.7243 | 1 |
Echinococcus multilocularis | dual specificity | 0.0375 | 0.7243 | 0.7302 |
Loa Loa (eye worm) | haspin protein kinase | 0.0481 | 0.9918 | 0.9918 |
Leishmania major | protein kinase, putative,dual-specificity protein kinase, putative | 0.0375 | 0.7243 | 1 |
Plasmodium vivax | serine/threonine protein kinase KIN, putative | 0.0086 | 0 | 0.5 |
Plasmodium vivax | cyclin dependent kinase 7 (cdk7), putative | 0.0086 | 0 | 0.5 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0375 | 0.7243 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.