Detailed information for compound 1513006

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 269.749 | Formula: C16H14ClN2+
  • H donors: 1 H acceptors: 0 LogP: 4.49 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: Clc1ccc(cc1)Nc1c[n+](C)c2c(c1)cccc2
  • InChi: 1S/C16H14ClN2/c1-19-11-15(10-12-4-2-3-5-16(12)19)18-14-8-6-13(17)7-9-14/h2-11,18H,1H3/q+1
  • InChiKey: KOBAPDFDGJLYAP-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus glycogen phosphorylase 0.0224 0.4664 0.4663
Brugia malayi photoreceptor-specific nuclear receptor 0.006 0.1024 0.1565
Brugia malayi Nuclear hormone receptor E75 0.0028 0.0321 0.0488
Loa Loa (eye worm) hypothetical protein 0.0016 0.005 0.0077
Schistosoma mansoni nuclear receptor 0.0028 0.0321 0.0488
Echinococcus multilocularis Glycosyl transferase, family 35 0.0224 0.4664 0.4663
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0106 1
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0533 0.256
Echinococcus granulosus FTZ F1 alpha 0.006 0.1024 0.1022
Brugia malayi nuclear hormone receptor family member odr-7 0.0028 0.0321 0.0488
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.006 0.1024 0.1565
Loa Loa (eye worm) ABC transporter transmembrane region family protein 0.0014 0.0003 0.0004
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0028 0.0321 0.0319
Brugia malayi nuclear hormone receptor 0.006 0.1024 0.1565
Loa Loa (eye worm) hypothetical protein 0.0028 0.0321 0.0492
Chlamydia trachomatis glycogen phosphorylase 0.0224 0.4664 0.5
Mycobacterium ulcerans glycogen phosphorylase GlgP 0.0097 0.1843 1
Loa Loa (eye worm) hypothetical protein 0.0028 0.0321 0.0492
Loa Loa (eye worm) hypothetical protein 0.0028 0.0321 0.0492
Schistosoma mansoni ap endonuclease 0.0019 0.0106 0.0159
Schistosoma mansoni inositol monophosphatase 0.0038 0.0533 0.0813
Schistosoma mansoni glycogen phosphorylase 0.0224 0.4664 0.7139
Schistosoma mansoni jumonji/arid domain-containing protein 0.006 0.1031 0.1574
Schistosoma mansoni phosphatidylserine receptor 0.0016 0.005 0.0073
Loa Loa (eye worm) hypothetical protein 0.006 0.1024 0.1568
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0032 0.0397 0.0604
Loa Loa (eye worm) hypothetical protein 0.0016 0.005 0.0077
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0028 0.0321 0.0319
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.006 0.1024 0.1568
Schistosoma mansoni retinoid-x-receptor (RXR) 0.006 0.1024 0.1565
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0028 0.0321 0.0488
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0308 0.6533 1
Loa Loa (eye worm) glycogen phosphorylase 0.0224 0.4664 0.714
Echinococcus granulosus Nuclear hormone receptor HR96 0.0028 0.0321 0.0319
Echinococcus multilocularis nuclear receptor nhr 48 0.0028 0.0321 0.0319
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0047 0.0733 0.0731
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.004 0.0037
Loa Loa (eye worm) hypothetical protein 0.0028 0.0321 0.0492
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0308 0.6533 0.6532
Onchocerca volvulus Protein ultraspiracle homolog 0.006 0.1024 0.1619
Echinococcus multilocularis voltage dependent calcium channel 0.0308 0.6533 0.6532
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0106 0.0228
Brugia malayi Nuclear hormone receptor family member nhr-19 0.006 0.1024 0.1565
Entamoeba histolytica glycogen phosphorylase, putative 0.0224 0.4664 1
Loa Loa (eye worm) transcription factor SMAD2 0.0118 0.2313 0.354
Echinococcus granulosus nuclear receptor 2DBD gamma 0.006 0.1024 0.1022
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0107 0.2076 1
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.004 0.0057
Echinococcus multilocularis glycogen phosphorylase 0.0224 0.4664 0.4663
Echinococcus granulosus phd:f box containing protein 0.0016 0.005 0.0048
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0032 0.0397 0.0394
Brugia malayi ecdysteroid receptor 0.006 0.1024 0.1565
Brugia malayi nuclear receptor RXR 0.0032 0.0397 0.0604
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.006 0.1024 0.1022
Brugia malayi Nuclear hormone receptor-like 1 0.0032 0.0397 0.0604
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.006 0.1024 0.1568
Brugia malayi Latrophilin receptor protein 2 0.0016 0.004 0.0057
Loa Loa (eye worm) hypothetical protein 0.0107 0.2076 0.3178
Brugia malayi Nuclear hormone receptor family member nhr-41 0.006 0.1024 0.1565
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.006 0.1024 0.1022
Brugia malayi Inositol-1 0.0038 0.0533 0.0813
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.004 0.0037
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.006 0.1024 0.1568
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0106 0.05
Brugia malayi jmjC domain containing protein 0.006 0.1031 0.1574
Echinococcus multilocularis jumonji domain containing 1A 0.0016 0.005 0.0048
Schistosoma mansoni hypothetical protein 0.0168 0.3411 0.522
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0038 0.0533 0.256
Loa Loa (eye worm) inositol-1 0.0038 0.0533 0.0816
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0034 0.0445 0.5
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0533 1
Brugia malayi nuclear receptor NHR-88 0.006 0.1024 0.1565
Loa Loa (eye worm) hypothetical protein 0.0016 0.004 0.0061
Schistosoma mansoni hypothetical protein 0.0034 0.0441 0.0672
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0533 0.256
Loa Loa (eye worm) nuclear hormone receptor 0.0028 0.0321 0.0492
Brugia malayi Nuclear hormone receptor E75 0.0028 0.0321 0.0488
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0016 0.005 0.0229
Loa Loa (eye worm) hypothetical protein 0.0032 0.0397 0.0607
Brugia malayi hypothetical protein 0.0032 0.0397 0.0604
Brugia malayi Nuclear hormone receptor family member nhr-19 0.006 0.1024 0.1565
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.006 0.1024 0.1568
Loa Loa (eye worm) jmjC domain-containing protein 0.006 0.1031 0.1578
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0028 0.0321 0.0492
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.0787 0.1202
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0308 0.6533 0.6532
Toxoplasma gondii transporter, cation channel family protein 0.0107 0.2076 1
Schistosoma mansoni glycogen phosphorylase 0.0097 0.1843 0.2818
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.006 0.1024 0.1619
Schistosoma mansoni coup transcription factor 0.006 0.1024 0.1565
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0308 0.6533 0.6532
Giardia lamblia Glycogen phosphorylase 0.0224 0.4664 1
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0106 0.0104
Brugia malayi jmjC domain containing protein 0.0016 0.005 0.0073
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.006 0.1024 0.1565
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.0533 0.0937
Schistosoma mansoni jumonji domain containing protein 0.0016 0.005 0.0073
Schistosoma mansoni nuclear receptor nhr-48 0.0028 0.0321 0.0488
Echinococcus granulosus Glycosyl transferase family 35 0.0224 0.4664 0.4663
Echinococcus granulosus lysine specific demethylase 6a 0.0016 0.005 0.0048
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.0787 0.1202
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0038 0.0533 0.1138
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0028 0.0321 0.0319
Schistosoma mansoni retinoic acid receptor RXR 0.006 0.1024 0.1565
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.006 0.1024 0.1022
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0106 0.0162
Schistosoma mansoni hypothetical protein 0.0168 0.3411 0.522
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0308 0.6533 0.6532
Brugia malayi Nuclear hormone receptor family member nhr-40 0.006 0.1024 0.1565
Echinococcus multilocularis inositol monophosphatase 1 0.0038 0.0533 0.0531
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.0787 0.1205
Echinococcus granulosus voltage dependent calcium channel 0.0107 0.2076 0.2074
Brugia malayi Nuclear hormone receptor family member nhr-14 0.006 0.1024 0.1565
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.006 0.1024 0.1568
Loa Loa (eye worm) hypothetical protein 0.0028 0.0321 0.0492
Giardia lamblia ABC transporter, putative 0.0014 0.0003 0.0005
Brugia malayi Nuclear hormone receptor family member nhr-25 0.006 0.1024 0.1565
Echinococcus multilocularis phd:f box containing protein 0.0016 0.005 0.0048
Loa Loa (eye worm) hypothetical protein 0.0028 0.0321 0.0492
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0106 0.05
Loa Loa (eye worm) hypothetical protein 0.0014 0.0003 0.0004
Entamoeba histolytica glycogen phosphorylase, putative 0.0097 0.1843 0.3947
Brugia malayi jmjC domain containing protein 0.0016 0.005 0.0073
Schistosoma mansoni hypothetical protein 0.0016 0.004 0.0057
Leishmania major hypothetical protein, conserved 0.0016 0.005 0.0896
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0016 0.005 0.0073
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0028 0.0321 0.0319
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0106 0.0159
Loa Loa (eye worm) hypothetical protein 0.0028 0.0321 0.0492
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0016 0.005 0.0048
Schistosoma mansoni ap endonuclease 0.0019 0.0106 0.0159
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.006 0.1031 0.1028
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.005 0.0229
Schistosoma mansoni nuclear hormone receptor 0.0028 0.0321 0.0488
Loa Loa (eye worm) hypothetical protein 0.0032 0.0397 0.0607
Onchocerca volvulus Glycogen phosphorylase homolog 0.0224 0.4664 1
Giardia lamblia Multidrug resistance-associated protein 1 0.0014 0.0003 0.0005
Brugia malayi jmjC domain containing protein 0.0016 0.005 0.0073
Brugia malayi Nuclear hormone receptor family member nhr-25 0.006 0.1024 0.1565
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.004 0.0037
Schistosoma mansoni nuclear hormone receptor 0.006 0.1024 0.1565
Schistosoma mansoni nuclear receptor 0.0028 0.0321 0.0488
Onchocerca volvulus 0.006 0.1024 0.1619
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0106 0.5
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.006 0.1031 0.1028
Brugia malayi nuclear hormone receptor 0.0028 0.0321 0.0488
Echinococcus granulosus nuclear receptor 2DBD gamma 0.006 0.1024 0.1022
Loa Loa (eye worm) hypothetical protein 0.006 0.1024 0.1568
Loa Loa (eye worm) voltage-dependent calcium channel 0.0107 0.2076 0.3178
Brugia malayi tailless protein 0.0028 0.0321 0.0488
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.006 0.1024 0.1022
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.004 0.0061
Echinococcus multilocularis lysine specific demethylase 5A 0.006 0.1031 0.1028
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.006 0.1024 0.1565
Brugia malayi ecdysone receptor 0.0028 0.0321 0.0488
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.006 0.1024 0.1022
Loa Loa (eye worm) MH2 domain-containing protein 0.0118 0.2313 0.354
Brugia malayi MH2 domain containing protein 0.0118 0.2313 0.3538
Schistosoma mansoni hypothetical protein 0.0016 0.004 0.0057
Loa Loa (eye worm) hypothetical protein 0.0028 0.0321 0.0492
Loa Loa (eye worm) hypothetical protein 0.0094 0.1789 0.2738
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.005 0.0229
Brugia malayi nuclear receptor NHR-88 0.0028 0.0321 0.0488
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0028 0.0321 0.0319
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.006 0.1024 0.1022
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0034 0.0445 0.1953
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.0533 0.0937
Echinococcus multilocularis thyroid hormone receptor alpha 0.006 0.1024 0.1022
Schistosoma mansoni Tr4/Tr2 (homologue) 0.006 0.1024 0.1565
Loa Loa (eye worm) hypothetical protein 0.0094 0.1789 0.2738
Echinococcus multilocularis voltage dependent calcium channel 0.0308 0.6533 0.6532
Schistosoma mansoni glycogen phosphorylase 0.0224 0.4664 0.7139
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0032 0.0397 0.0607
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0028 0.0321 0.0488
Brugia malayi Nuclear hormone receptor family member nhr-1 0.006 0.1024 0.1565
Echinococcus multilocularis FTZ F1 alpha 0.006 0.1024 0.1022
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.005 0.0077
Echinococcus multilocularis lysine specific demethylase 6a 0.0016 0.005 0.0048
Loa Loa (eye worm) hypothetical protein 0.0028 0.0321 0.0492
Brugia malayi jmjC domain containing protein 0.006 0.1031 0.1574
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0107 0.2076 1
Loa Loa (eye worm) hypothetical protein 0.0032 0.0397 0.0607
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0032 0.0397 0.0394
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0106 0.0104
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0308 0.6533 0.6532
Schistosoma mansoni protein phosphatase 2C 0.0016 0.005 0.0073
Echinococcus granulosus nuclear receptor nhr 48 0.0028 0.0321 0.0319
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0308 0.6533 1
Loa Loa (eye worm) hypothetical protein 0.006 0.1024 0.1568
Echinococcus granulosus ecdysone induced protein 78C 0.006 0.1024 0.1022
Loa Loa (eye worm) hypothetical protein 0.0049 0.0787 0.1205
Echinococcus multilocularis GPCR, family 2 0.0016 0.004 0.0037
Schistosoma mansoni hypothetical protein 0.0016 0.004 0.0057
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0106 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0733 0.1119
Schistosoma mansoni inositol monophosphatase 0.0038 0.0533 0.0813
Brugia malayi Nuclear hormone receptor family member nhr-3 0.006 0.1024 0.1565
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0733 0.1119
Echinococcus multilocularis JmjC domain containing protein 4 0.0016 0.005 0.0048
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.006 0.1024 0.1565
Trichomonas vaginalis glycogen phosphorylase, putative 0.0224 0.4664 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0047 0.0733 0.0731
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0047 0.0733 0.1123
Loa Loa (eye worm) hypothetical protein 0.0028 0.0321 0.0492
Loa Loa (eye worm) hypothetical protein 0.0028 0.0321 0.0492
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.006 0.1024 0.1022
Loa Loa (eye worm) hypothetical protein 0.006 0.1024 0.1568
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0028 0.0321 0.0488
Echinococcus multilocularis glycogen phosphorylase 0.0224 0.4664 0.4663
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0032 0.0397 0.0604
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0016 0.005 0.0048
Entamoeba histolytica glycogenphosphorylase, putative 0.0097 0.1843 0.3947
Brugia malayi carbohydrate phosphorylase 0.0224 0.4664 0.7139
Loa Loa (eye worm) hypothetical protein 0.006 0.1024 0.1568
Schistosoma mansoni zinc finger protein 0.0028 0.0321 0.0488
Loa Loa (eye worm) hypothetical protein 0.0016 0.005 0.0077
Trichomonas vaginalis inositol monophosphatase, putative 0.0038 0.0533 0.0937
Schistosoma mansoni voltage-gated cation channel 0.0308 0.6533 1
Echinococcus multilocularis ecdysone induced protein 78C 0.006 0.1024 0.1022
Echinococcus granulosus jumonji domain containing 1A 0.0016 0.005 0.0048
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0028 0.0321 0.0319
Echinococcus granulosus thyroid hormone receptor alpha 0.0028 0.0321 0.0319
Schistosoma mansoni thyroid hormone receptor 0.006 0.1024 0.1565
Loa Loa (eye worm) hypothetical protein 0.0028 0.0321 0.0492
Loa Loa (eye worm) hypothetical protein 0.0032 0.0397 0.0607
Onchocerca volvulus Bile acid receptor homolog 0.006 0.1024 0.1619
Loa Loa (eye worm) steroid hormone receptor 0.006 0.1024 0.1568
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0028 0.0321 0.0319
Schistosoma mansoni phd/f-box containing protein 0.0016 0.005 0.0073
Brugia malayi Steroid receptor seven-up type 2 0.006 0.1024 0.1565
Schistosoma mansoni hypothetical protein 0.0016 0.004 0.0057
Brugia malayi steroid hormone receptor 0.006 0.1024 0.1565
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.005 0.0077
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0106 0.1953
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0533 0.256
Brugia malayi Nuclear hormone receptor family member nhr-49 0.006 0.1024 0.1565
Brugia malayi hypothetical protein 0.0028 0.0321 0.0488
Loa Loa (eye worm) hypothetical protein 0.0308 0.6533 1
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0038 0.0533 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.006 0.1024 0.1568
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.006 0.1024 0.1022
Echinococcus granulosus voltage dependent calcium channel 0.0308 0.6533 0.6532
Brugia malayi jmjC domain containing protein 0.0016 0.005 0.0073
Echinococcus granulosus geminin 0.0168 0.3411 0.341
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.005 0.0077
Echinococcus multilocularis geminin 0.0168 0.3411 0.341
Brugia malayi hypothetical protein 0.0028 0.0321 0.0488
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.006 0.1024 0.1022
Echinococcus granulosus retinoic acid receptor rxr beta a 0.006 0.1024 0.1022
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.006 0.1024 0.1568
Loa Loa (eye worm) hypothetical protein 0.0034 0.0441 0.0675
Loa Loa (eye worm) hypothetical protein 0.006 0.1024 0.1568
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0016 0.005 0.0229
Brugia malayi nuclear hormone receptor family member nhr-6 0.0028 0.0321 0.0488
Mycobacterium tuberculosis Probable glycogen phosphorylase GlgP 0.0097 0.1843 1
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0106 0.05
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0047 0.0733 0.0731
Schistosoma mansoni jumonji domain containing protein 0.006 0.1031 0.1574
Trichomonas vaginalis glycogen phosphorylase, putative 0.0224 0.4664 1
Brugia malayi conserved hypotetical protein 0.0028 0.0321 0.0488
Brugia malayi Nuclear hormone receptor-like 1 0.006 0.1024 0.1565
Echinococcus granulosus JmjC domain containing protein 4 0.0016 0.005 0.0048
Loa Loa (eye worm) hypothetical protein 0.0032 0.0397 0.0607
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0308 0.6533 0.6532
Brugia malayi nuclear receptor NHR-67 0.0028 0.0321 0.0488
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.006 0.1024 0.1565
Schistosoma mansoni steroid hormone receptor ad4bp 0.006 0.1024 0.1565
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0047 0.0733 0.1119
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.004 0.0037
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0038 0.0533 0.2459
Loa Loa (eye worm) hypothetical protein 0.0014 0.0003 0.0004
Giardia lamblia MRP-like ABC transporter 0.0014 0.0003 0.0005
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0308 0.6533 1
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.006 0.1024 0.1022
Schistosoma mansoni jumonji/arid domain-containing protein 0.006 0.1031 0.1574
Brugia malayi Nuclear hormone receptor-like 1 0.0032 0.0397 0.0604
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0308 0.6533 0.6532
Loa Loa (eye worm) hypothetical protein 0.0028 0.0321 0.0492
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.0441 0.0672
Toxoplasma gondii exonuclease III APE 0.0019 0.0106 0.05
Loa Loa (eye worm) nuclear receptor NHR-67 0.0028 0.0321 0.0492
Schistosoma mansoni RAR-like nuclear receptor 0.006 0.1024 0.1565
Echinococcus granulosus Nuclear hormone receptor HR96 0.0028 0.0321 0.0319
Entamoeba histolytica glycogen phosphorylase, putative 0.0224 0.4664 1
Brugia malayi orphan nuclear receptor NR2E1 0.0028 0.0321 0.0488
Loa Loa (eye worm) DR-78 0.0028 0.0321 0.0492
Brugia malayi hypothetical protein 0.0032 0.0397 0.0604
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0047 0.0733 0.0731
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0016 0.005 0.0229
Brugia malayi nuclear receptor RXR 0.0028 0.0321 0.0488
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.006 0.1024 0.1565
Giardia lamblia Multidrug resistance-associated protein 1 0.0014 0.0003 0.0005
Echinococcus granulosus inositol monophosphatase 1 0.0038 0.0533 0.0531
Entamoeba histolytica glycogen phosphorylase, putative 0.0097 0.1843 0.3947
Echinococcus granulosus lysine specific demethylase 5A 0.006 0.1031 0.1028
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0106 0.0222
Schistosoma mansoni thyroid hormone receptor 0.006 0.1024 0.1565
Schistosoma mansoni nuclear hormone receptor 0.0028 0.0321 0.0488
Loa Loa (eye worm) hypothetical protein 0.006 0.1024 0.1568
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0733 0.1119
Echinococcus granulosus glycogen phosphorylase 0.0224 0.4664 0.4663
Loa Loa (eye worm) calcium channel 0.0308 0.6533 1
Echinococcus granulosus GPCR family 2 0.0016 0.004 0.0037
Loa Loa (eye worm) hypothetical protein 0.006 0.1024 0.1568
Brugia malayi Nuclear hormone receptor family member nhr-31 0.006 0.1024 0.1565
Toxoplasma gondii hypothetical protein 0.0094 0.1789 0.8614

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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