Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | membrane metallo-endopeptidase | Starlite/ChEMBL | References |
Homo sapiens | natriuretic peptide A | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0114 | 0.1962 | 1 |
Mycobacterium ulcerans | protoporphyrinogen oxidase | 0.035 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0947 | 0.4828 |
Echinococcus multilocularis | protoporphyrinogen oxidase | 0.035 | 1 | 1 |
Mycobacterium tuberculosis | Probable protoporphyrinogen oxidase HemY (protoporphyrinogen-IX oxidase) (protoporphyrinogenase) (PPO) | 0.0304 | 0.8431 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0114 | 0.1962 | 1 |
Schistosoma mansoni | family M13 unassigned peptidase (M13 family) | 0.0114 | 0.1962 | 0.1933 |
Loa Loa (eye worm) | hypothetical protein | 0.0114 | 0.1962 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.1015 | 0.5172 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.1015 | 0.5172 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.1015 | 0.5172 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.1015 | 0.5172 |
Echinococcus granulosus | protoporphyrinogen oxidase | 0.0304 | 0.8431 | 1 |
Loa Loa (eye worm) | peptidase family M13 containing protein | 0.0084 | 0.0947 | 0.4828 |
Brugia malayi | Peptidase family M13 containing protein | 0.0114 | 0.1962 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.1015 | 0.5172 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0947 | 0.4828 |
Toxoplasma gondii | peptidase family M13 protein | 0.0114 | 0.1962 | 0.5 |
Onchocerca volvulus | 0.0056 | 0 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.1015 | 0.5172 |
Mycobacterium leprae | PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) | 0.035 | 1 | 1 |
Brugia malayi | Hypothetical zinc metalloproteinase T16A9.4 | 0.0114 | 0.1962 | 0.5 |
Schistosoma mansoni | Protoporphyrinogen oxidase chloroplast/mitochondrial precursor | 0.035 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0947 | 0.4828 |
Loa Loa (eye worm) | peptidase family M13 containing protein | 0.0084 | 0.0947 | 0.4828 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0947 | 0.4828 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.