Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0321 | 0.4442 | 0.3983 | |
Loa Loa (eye worm) | hypothetical protein | 0.0188 | 0.229 | 0.229 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.15 | 0.15 |
Schistosoma mansoni | family M13 unassigned peptidase (M13 family) | 0.0095 | 0.079 | 0.345 |
Loa Loa (eye worm) | hypothetical protein | 0.0142 | 0.1552 | 0.1552 |
Trypanosoma cruzi | phospholipase A1, putative | 0.0321 | 0.4442 | 1 |
Echinococcus multilocularis | endothelin converting enzyme 1 | 0.0188 | 0.229 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0049 | 0.0053 | 0.023 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0048 | 0.004 | 0.004 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.15 | 0.15 |
Loa Loa (eye worm) | hypothetical protein | 0.0188 | 0.229 | 0.229 |
Mycobacterium leprae | probable zinc metalloprotease | 0.0188 | 0.229 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0049 | 0.0053 | 0.023 |
Brugia malayi | Hypothetical zinc metalloproteinase T16A9.4 | 0.0188 | 0.229 | 0.229 |
Schistosoma mansoni | neprilysin | 0.0049 | 0.0053 | 0.023 |
Loa Loa (eye worm) | peptidase family M13 containing protein | 0.0139 | 0.15 | 0.15 |
Schistosoma mansoni | hypothetical protein | 0.0049 | 0.0053 | 0.023 |
Echinococcus granulosus | endothelin converting enzyme 1 | 0.0188 | 0.229 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0049 | 0.0053 | 0.023 |
Schistosoma mansoni | neprilysin-2 (M13 family) | 0.0095 | 0.079 | 0.345 |
Trypanosoma cruzi | phospholipase A1, putative | 0.0321 | 0.4442 | 1 |
Schistosoma mansoni | family M13 unassigned peptidase (M13 family) | 0.0049 | 0.0053 | 0.023 |
Schistosoma mansoni | family M13 non-peptidase homologue (M13 family) | 0.0095 | 0.079 | 0.345 |
Schistosoma mansoni | hypothetical protein | 0.0049 | 0.0053 | 0.023 |
Trypanosoma brucei | phospholipase A1, putative | 0.0321 | 0.4442 | 0.5 |
Loa Loa (eye worm) | peptidase family M13 containing protein | 0.0139 | 0.15 | 0.15 |
Loa Loa (eye worm) | hypothetical protein | 0.0142 | 0.1552 | 0.1552 |
Toxoplasma gondii | peptidase family M13 protein | 0.0188 | 0.229 | 0.5 |
Onchocerca volvulus | 0.0321 | 0.4442 | 0.3983 | |
Mycobacterium ulcerans | zinc metalloprotease | 0.0188 | 0.229 | 0.5 |
Onchocerca volvulus | Phospholipase A2 homolog | 0.0666 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0267 | 0.3562 | 0.3562 |
Onchocerca volvulus | 0.0321 | 0.4442 | 0.3983 | |
Brugia malayi | Peptidase family M13 containing protein | 0.0188 | 0.229 | 0.229 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.15 | 0.15 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.15 | 0.15 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.004 | 0.0174 |
Schistosoma mansoni | Nep2 peptidase (M13 family) | 0.0095 | 0.079 | 0.345 |
Loa Loa (eye worm) | platelet-activating factor acetylhydrolase | 0.0321 | 0.4442 | 0.4442 |
Loa Loa (eye worm) | hypothetical protein | 0.0142 | 0.1552 | 0.1552 |
Onchocerca volvulus | Phospholipase A2 homolog | 0.0267 | 0.3562 | 0.3031 |
Loa Loa (eye worm) | hypothetical protein | 0.0142 | 0.1552 | 0.1552 |
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.0762 | 0.0762 |
Loa Loa (eye worm) | hypothetical protein | 0.0142 | 0.1552 | 0.1552 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.004 | 0.0174 |
Leishmania major | phospholipase A1, putative | 0.0321 | 0.4442 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0049 | 0.0053 | 0.023 |
Loa Loa (eye worm) | hypothetical protein | 0.0188 | 0.229 | 0.229 |
Schistosoma mansoni | family M13 unassigned peptidase (M13 family) | 0.0188 | 0.229 | 1 |
Schistosoma mansoni | family M13 unassigned peptidase (M13 family) | 0.0095 | 0.079 | 0.345 |
Loa Loa (eye worm) | hypothetical protein | 0.0142 | 0.1552 | 0.1552 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.004 | 0.0174 |
Mycobacterium tuberculosis | Probable zinc metalloprotease Zmp1 | 0.0188 | 0.229 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0666 | 1 | 1 |
Brugia malayi | Platelet-activating factor acetylhydrolase, plasma/intracellular isoform II family protein | 0.0321 | 0.4442 | 0.4442 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0048 | 0.004 | 0.004 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.