Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | opioid receptor, delta 1 | Starlite/ChEMBL | References |
Homo sapiens | potassium voltage-gated channel, subfamily H (eag-related), member 2 | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | voltage-gated potassium channel | 0.0013 | 0.0095 | 0.1414 |
Trypanosoma brucei | leucine-rich repeat protein (LRRP), putative | 0.0008 | 0.001 | 0.5 |
Echinococcus multilocularis | cyclic nucleotide gated cation channel | 0.0009 | 0.0029 | 0.0019 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0042 | 0.0557 | 1 |
Entamoeba histolytica | leucine rich repeat / protein phosphatase 2C domain containing protein | 0.0008 | 0.001 | 0.5 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0009 | 0.0029 | 0.043 |
Schistosoma mansoni | cyclic-nucleotide-gated cation channel | 0.0009 | 0.0029 | 0.043 |
Schistosoma mansoni | hyperpolarization activated cyclic nucleotide-gated potassium channel | 0.0009 | 0.0029 | 0.043 |
Schistosoma mansoni | cyclic-nucleotide-gated cation channel | 0.0009 | 0.0029 | 0.043 |
Schistosoma mansoni | ras suppressor protein 1 rsu1 | 0.0008 | 0.001 | 0.0145 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0013 | 0.0095 | 0.0085 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0009 | 0.0029 | 0.0349 |
Echinococcus multilocularis | potassium:sodium hyperpolarization activated | 0.0009 | 0.0029 | 0.0019 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0013 | 0.0095 | 0.1414 |
Brugia malayi | Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog | 0.0045 | 0.0604 | 1 |
Brugia malayi | Cyclic-nucleotide gated cation channel | 0.0009 | 0.0029 | 0.0321 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0013 | 0.0095 | 0.0085 |
Echinococcus granulosus | cyclic nucleotide gated cation channel | 0.0009 | 0.0029 | 0.0019 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0029 | 0.0321 |
Echinococcus multilocularis | cyclic nucleotide gated cation channel alpha 3 | 0.0009 | 0.0029 | 0.0019 |
Echinococcus multilocularis | voltage gated potassium channel | 0.0013 | 0.0095 | 0.0085 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0095 | 0.143 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0042 | 0.0557 | 1 |
Trypanosoma cruzi | protein phosphatase 1, regulatory subunit, putative | 0.0008 | 0.001 | 0.5 |
Echinococcus granulosus | voltage gated potassium channel | 0.0013 | 0.0095 | 0.0085 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0049 | 0.067 | 1 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.0045 | 0.0604 | 1 |
Onchocerca volvulus | 0.0272 | 0.426 | 0.5 | |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0045 | 0.0604 | 0.0595 |
Loa Loa (eye worm) | cyclic-nucleotide gated cation channel | 0.0009 | 0.0029 | 0.0321 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0008 | 0.001 | 0.5 |
Schistosoma mansoni | hyperpolarization activated cyclic nucleotide-gated potassium channel | 0.0009 | 0.0029 | 0.043 |
Schistosoma mansoni | cyclic-nucleotide-gated cation channel | 0.0009 | 0.0029 | 0.043 |
Echinococcus multilocularis | hyperpolarization activated cyclic | 0.0009 | 0.0029 | 0.0019 |
Echinococcus granulosus | cyclic nucleotide gated cation channel | 0.0009 | 0.0029 | 0.0019 |
Echinococcus multilocularis | hyperpolarization activated cyclic | 0.0009 | 0.0029 | 0.0019 |
Echinococcus granulosus | potassium:sodium hyperpolarization activated | 0.0009 | 0.0029 | 0.0019 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0049 | 0.067 | 1 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0628 | 1 | 1 |
Echinococcus granulosus | hyperpolarization activated cyclic | 0.0009 | 0.0029 | 0.0019 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0009 | 0.0029 | 0.0349 |
Echinococcus granulosus | hyperpolarization activated cyclic | 0.0009 | 0.0029 | 0.0019 |
Brugia malayi | Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog | 0.0013 | 0.0095 | 0.143 |
Trypanosoma cruzi | protein phosphatase 1, regulatory subunit, putative | 0.0008 | 0.001 | 0.5 |
Loa Loa (eye worm) | cyclic-nucleotide gated cation channel | 0.0009 | 0.0029 | 0.0321 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.051 | 0.8407 |
Plasmodium vivax | protein phosphatases PP1 regulatory subunit sds22, putative | 0.0008 | 0.001 | 0.5 |
Echinococcus granulosus | cyclic nucleotide gated cation channel alpha 3 | 0.0009 | 0.0029 | 0.0019 |
Trypanosoma brucei | protein phosphatase 1, regulatory subunit, putative | 0.0008 | 0.001 | 0.5 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0045 | 0.0604 | 0.0595 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.