Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | carnitine O palmitoyltransferase 1, liver | 0.1135 | 0.4214 | 1 |
Loa Loa (eye worm) | choline O-acetyltransferase | 0.0231 | 0.0779 | 0.0779 |
Loa Loa (eye worm) | choline/Carnitine O-acyltransferase | 0.0323 | 0.1128 | 0.1128 |
Trypanosoma cruzi | choline/carnitine O-acyltransferase, putative | 0.1135 | 0.4214 | 1 |
Echinococcus granulosus | carnitine O palmitoyltransferase 1 liver | 0.1135 | 0.4214 | 1 |
Onchocerca volvulus | 0.0231 | 0.0779 | 0.5 | |
Loa Loa (eye worm) | carnitine O-palmitoyltransferase I isoform | 0.0231 | 0.0779 | 0.0779 |
Onchocerca volvulus | 0.0231 | 0.0779 | 0.5 | |
Echinococcus multilocularis | carnitine O palmitoyltransferase 2 | 0.0323 | 0.1128 | 0.1015 |
Trypanosoma cruzi | carnitine O-palmitoyltransferase II, putative | 0.0323 | 0.1128 | 0.1015 |
Echinococcus granulosus | carnitine O palmitoyltransferase 2 | 0.0323 | 0.1128 | 0.1015 |
Brugia malayi | Choline O-acetyltransferase | 0.0231 | 0.0779 | 0.0779 |
Schistosoma mansoni | choline o-acyltransferase | 0.0231 | 0.0779 | 0.5 |
Brugia malayi | Choline/Carnitine o-acyltransferase family protein | 0.0323 | 0.1128 | 0.1128 |
Brugia malayi | Choline/Carnitine o-acyltransferase family protein | 0.0231 | 0.0779 | 0.0779 |
Trypanosoma cruzi | choline/carnitine O-acyltransferase, putative | 0.1135 | 0.4214 | 1 |
Onchocerca volvulus | 0.0231 | 0.0779 | 0.5 | |
Trypanosoma brucei | carnitine O-palmitoyltransferase II, putative | 0.0323 | 0.1128 | 1 |
Onchocerca volvulus | 0.0231 | 0.0779 | 0.5 | |
Schistosoma mansoni | choline o-acyltransferase | 0.0231 | 0.0779 | 0.5 |
Leishmania major | choline/Carnitine o-acyltransferase-like protein | 0.1135 | 0.4214 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0231 | 0.0779 | 0.0779 |
Brugia malayi | Choline O-acetyltransferase | 0.0231 | 0.0779 | 0.0779 |
Leishmania major | carnitine palmitoyltransferase-like protein | 0.0323 | 0.1128 | 0.1015 |
Loa Loa (eye worm) | hypothetical protein | 0.2657 | 1 | 1 |
Species name | Source | Reference | Is orphan |
---|---|---|---|
Homo sapiens | ChEMBL23 | 22014546 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.