Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | carnitine palmitoyltransferase-like protein | 0.1871 | 0.2288 | 0.2341 |
Brugia malayi | Metabotropic glutamate receptor precursor. | 0.004 | 0.0008 | 0.0005 |
Loa Loa (eye worm) | carnitine O-palmitoyltransferase I isoform | 0.1045 | 0.126 | 0.1253 |
Echinococcus granulosus | carnitine O palmitoyltransferase 2 | 0.1871 | 0.2288 | 0.405 |
Schistosoma mansoni | choline o-acyltransferase | 0.1045 | 0.126 | 1 |
Brugia malayi | Choline O-acetyltransferase | 0.1045 | 0.126 | 0.1257 |
Loa Loa (eye worm) | hypothetical protein | 0.1045 | 0.126 | 0.1253 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0019 | 0.0011 |
Loa Loa (eye worm) | choline/Carnitine O-acyltransferase | 0.1871 | 0.2288 | 0.2282 |
Onchocerca volvulus | 0.1045 | 0.126 | 0.5 | |
Onchocerca volvulus | 0.1045 | 0.126 | 0.5 | |
Echinococcus granulosus | metabotropic glutamate receptor 5 | 0.0049 | 0.0019 | 0.0034 |
Loa Loa (eye worm) | hypothetical protein | 0.8064 | 1 | 1 |
Schistosoma mansoni | metabotropic glutamate receptor 2 3 (mglur group 2) | 0.0045 | 0.0015 | 0.0117 |
Brugia malayi | Choline/Carnitine o-acyltransferase family protein | 0.1045 | 0.126 | 0.1257 |
Leishmania major | choline/Carnitine o-acyltransferase-like protein | 0.457 | 0.5649 | 1 |
Brugia malayi | Choline O-acetyltransferase | 0.1045 | 0.126 | 0.1257 |
Schistosoma mansoni | choline o-acyltransferase | 0.1045 | 0.126 | 1 |
Echinococcus granulosus | choline O acetyltransferase | 0.1045 | 0.126 | 0.2231 |
Trypanosoma cruzi | choline/carnitine O-acyltransferase, putative | 0.457 | 0.5649 | 1 |
Brugia malayi | Choline/Carnitine o-acyltransferase family protein | 0.1871 | 0.2288 | 0.2285 |
Onchocerca volvulus | 0.1045 | 0.126 | 0.5 | |
Echinococcus multilocularis | choline O acetyltransferase | 0.1045 | 0.126 | 0.2231 |
Loa Loa (eye worm) | choline O-acetyltransferase | 0.1045 | 0.126 | 0.1253 |
Trypanosoma brucei | carnitine O-palmitoyltransferase II, putative | 0.1871 | 0.2288 | 1 |
Trypanosoma cruzi | carnitine O-palmitoyltransferase II, putative | 0.1871 | 0.2288 | 0.2341 |
Onchocerca volvulus | 0.1045 | 0.126 | 0.5 | |
Echinococcus multilocularis | metabotropic glutamate receptor 5 | 0.0049 | 0.0019 | 0.0034 |
Echinococcus multilocularis | carnitine O palmitoyltransferase 1, liver | 0.457 | 0.5649 | 1 |
Echinococcus multilocularis | carnitine O palmitoyltransferase 2 | 0.1871 | 0.2288 | 0.405 |
Trypanosoma cruzi | choline/carnitine O-acyltransferase, putative | 0.457 | 0.5649 | 1 |
Echinococcus granulosus | carnitine O palmitoyltransferase 1 liver | 0.457 | 0.5649 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.