Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0164 | 0.2487 | 0.4421 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase | 0.0131 | 0.0037 | 0.0037 |
Onchocerca volvulus | 0.0131 | 0.0037 | 0.5 | |
Echinococcus multilocularis | contactin neuroglian septate junction protein | 0.0164 | 0.2487 | 0.2487 |
Echinococcus multilocularis | neuroglian | 0.0164 | 0.2487 | 0.2487 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase | 0.0164 | 0.2487 | 0.2487 |
Loa Loa (eye worm) | hypothetical protein | 0.0164 | 0.2487 | 0.4421 |
Echinococcus granulosus | neurotracting:lsamp:neurotrimin:obcam | 0.0137 | 0.0476 | 0.0476 |
Loa Loa (eye worm) | hypothetical protein | 0.0207 | 0.5577 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0164 | 0.2449 | 0.4354 |
Schistosoma mansoni | ephrin receptor | 0.0141 | 0.0773 | 0.0921 |
Brugia malayi | Fibronectin type III domain containing protein | 0.0207 | 0.5577 | 1 |
Schistosoma mansoni | nephrin | 0.0164 | 0.2487 | 0.3066 |
Echinococcus multilocularis | Down syndrome cell adhesion molecule | 0.0137 | 0.0513 | 0.0513 |
Schistosoma mansoni | receptor tyrosine phosphatase type r2a | 0.0164 | 0.2487 | 0.3066 |
Loa Loa (eye worm) | hypothetical protein | 0.0207 | 0.5577 | 1 |
Echinococcus granulosus | nephrin | 0.0131 | 0.0037 | 0.0037 |
Echinococcus granulosus | insulin growth factor 1 receptor beta | 0.0141 | 0.0773 | 0.0773 |
Loa Loa (eye worm) | TK/KIN16 protein kinase | 0.0174 | 0.3185 | 0.5681 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase | 0.0164 | 0.2487 | 0.2487 |
Echinococcus granulosus | neuroglian | 0.0164 | 0.2487 | 0.2487 |
Schistosoma mansoni | cell adhesion molecule | 0.024 | 0.8027 | 1 |
Echinococcus multilocularis | roundabout 2 | 0.0164 | 0.2487 | 0.2487 |
Schistosoma mansoni | nephrin | 0.0234 | 0.7551 | 0.9404 |
Echinococcus granulosus | roundabout 2 | 0.0164 | 0.2487 | 0.2487 |
Schistosoma mansoni | cell adhesion molecule | 0.0164 | 0.2487 | 0.3066 |
Echinococcus multilocularis | titin | 0.0131 | 0.0037 | 0.0037 |
Loa Loa (eye worm) | hypothetical protein | 0.0164 | 0.2449 | 0.4354 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0137 | 0.0513 | 0.0859 |
Echinococcus granulosus | titin | 0.0131 | 0.0037 | 0.0037 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0137 | 0.0513 | 0.0859 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0207 | 0.5577 | 1 |
Onchocerca volvulus | 0.0131 | 0.0037 | 0.5 | |
Echinococcus granulosus | roundabout 2 | 0.0164 | 0.2487 | 0.2487 |
Brugia malayi | hypothetical protein | 0.0207 | 0.5577 | 1 |
Schistosoma mansoni | neuroglian | 0.0164 | 0.2487 | 0.3066 |
Echinococcus granulosus | Down syndrome cell adhesion molecule | 0.0137 | 0.0513 | 0.0513 |
Loa Loa (eye worm) | hypothetical protein | 0.0137 | 0.0476 | 0.0792 |
Schistosoma mansoni | cell adhesion molecule | 0.0164 | 0.2487 | 0.3066 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0164 | 0.2487 | 0.4421 |
Echinococcus granulosus | contactin | 0.0164 | 0.2487 | 0.2487 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0164 | 0.2487 | 0.4421 |
Echinococcus granulosus | titin | 0.0131 | 0.0037 | 0.0037 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase F | 0.0164 | 0.2487 | 0.2487 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0164 | 0.2487 | 0.4421 |
Echinococcus multilocularis | insulin growth factor 1 receptor beta | 0.0141 | 0.0773 | 0.0773 |
Loa Loa (eye worm) | hypothetical protein | 0.0207 | 0.5577 | 1 |
Onchocerca volvulus | 0.0131 | 0.0037 | 0.5 | |
Echinococcus multilocularis | roundabout 2 | 0.0267 | 1 | 1 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0174 | 0.3185 | 0.5681 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase | 0.0164 | 0.2487 | 0.2487 |
Echinococcus multilocularis | roundabout 2 | 0.0164 | 0.2487 | 0.2487 |
Loa Loa (eye worm) | CAMK/MLCK protein kinase | 0.0164 | 0.2487 | 0.4421 |
Echinococcus multilocularis | transfer RNA-Phe | 0.0131 | 0.0037 | 0.0037 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.