Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | hypothetical protein | 0.0134 | 0.9918 | 1 |
Echinococcus granulosus | serine:threonine protein kinase haspin | 0.0134 | 0.9918 | 1 |
Echinococcus granulosus | serine:threonine protein kinase haspin | 0.0134 | 0.9918 | 1 |
Brugia malayi | hypothetical protein | 0.0134 | 0.9918 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0105 | 0.7243 | 1 |
Echinococcus multilocularis | serine:threonine protein kinase haspin | 0.0134 | 0.9918 | 1 |
Trypanosoma brucei | dual specificity tyrosine-phosphorylation-regulated kinase 2, putative | 0.0105 | 0.7243 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0105 | 0.7243 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.0105 | 0.7243 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0105 | 0.7243 | 0.7302 |
Plasmodium vivax | serine/threonine protein kinase KIN, putative | 0.0024 | 0 | 0.5 |
Echinococcus granulosus | dual specificity | 0.0105 | 0.7243 | 0.7302 |
Echinococcus multilocularis | dual specificity | 0.0105 | 0.7243 | 0.7302 |
Toxoplasma gondii | cell-cycle-associated protein kinase DYRK2, putative | 0.0105 | 0.7243 | 0.5 |
Loa Loa (eye worm) | haspin protein kinase | 0.0134 | 0.9918 | 0.9918 |
Giardia lamblia | Kinase, CMGC DYRK | 0.0105 | 0.7243 | 1 |
Echinococcus granulosus | serine:threonine protein kinase haspin | 0.0134 | 0.9918 | 1 |
Trypanosoma cruzi | dual specificity tyrosine-phosphorylation-regulated kinase 2, putative | 0.0105 | 0.7243 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0105 | 0.7243 | 1 |
Echinococcus multilocularis | serine:threonine protein kinase haspin | 0.0134 | 0.9918 | 1 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0105 | 0.7243 | 1 |
Brugia malayi | GSG2 | 0.0134 | 0.9918 | 1 |
Echinococcus granulosus | dual specificity | 0.0105 | 0.7243 | 0.7302 |
Plasmodium falciparum | MO15-related protein kinase | 0.0024 | 0 | 0.5 |
Plasmodium vivax | cyclin dependent kinase 7 (cdk7), putative | 0.0024 | 0 | 0.5 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0105 | 0.7243 | 1 |
Loa Loa (eye worm) | haspin protein kinase | 0.0134 | 0.9918 | 0.9918 |
Echinococcus granulosus | dual specificity | 0.0105 | 0.7243 | 0.7302 |
Echinococcus multilocularis | dual specificity | 0.0105 | 0.7243 | 0.7302 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0105 | 0.7243 | 1 |
Loa Loa (eye worm) | CMGC/DYRK/DYRK2 protein kinase | 0.0105 | 0.7243 | 0.7243 |
Leishmania major | protein kinase, putative,dual-specificity protein kinase, putative | 0.0105 | 0.7243 | 1 |
Echinococcus multilocularis | dual specificity | 0.0105 | 0.7243 | 0.7302 |
Brugia malayi | Dual-specificity tyrosine-phosphorylation regulated kinase 2 | 0.0105 | 0.7243 | 0.7302 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0105 | 0.7243 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.