Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Giardia lamblia | Nitric oxide synthase, inducible | 0.0081 | 0.3181 | 1 |
Plasmodium vivax | hypothetical protein, conserved | 0.0035 | 0.1154 | 0.3033 |
Trypanosoma cruzi | 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative | 0.0027 | 0.0811 | 0.0744 |
Echinococcus multilocularis | methionine synthase reductase | 0.0056 | 0.2099 | 0.5043 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0019 | 0.0465 | 0.1015 |
Schistosoma mansoni | 5-methyl tetrahydrofolate-homocysteine methyltransferase reductase | 0.0056 | 0.2099 | 0.5043 |
Brugia malayi | regulator of G-protein signaling egl-10 | 0.001 | 0.0055 | 0.0064 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0053 | 0.0062 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.001 | 0.0055 | 0.0005 |
Brugia malayi | flavodoxin family protein | 0.0091 | 0.3638 | 0.4259 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0053 | 0.0062 |
Leishmania major | 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative | 0.0027 | 0.0811 | 0.0744 |
Trichomonas vaginalis | Citrate lyase beta chain, putative | 0.0027 | 0.0811 | 0.1092 |
Brugia malayi | steroid hormone receptor | 0.001 | 0.0053 | 0.0062 |
Trypanosoma brucei | NADPH--cytochrome P450 reductase, putative | 0.0091 | 0.3638 | 0.3591 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0102 | 0.4111 | 1 |
Echinococcus multilocularis | cytochrome b5 reductase 4 | 0.001 | 0.0073 | 0.0049 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.001 | 0.0053 | 0.0062 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0067 | 0.2579 | 0.6226 |
Entamoeba histolytica | type A flavoprotein, putative | 0.0035 | 0.1154 | 0.6653 |
Schistosoma mansoni | cytochrome B5 | 0.001 | 0.0073 | 0.0049 |
Loa Loa (eye worm) | cytochrome b5 reductase 4 | 0.001 | 0.0073 | 0.0085 |
Echinococcus granulosus | segment polarity protein dishevelled | 0.0012 | 0.0126 | 0.0181 |
Loa Loa (eye worm) | G protein signaling regulator EGL-10 | 0.001 | 0.0055 | 0.0064 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0126 | 0.0148 |
Echinococcus multilocularis | Pleckstrin G protein, interacting region | 0.001 | 0.0055 | 0.0005 |
Echinococcus granulosus | cytochrome b5 reductase 4 | 0.001 | 0.0073 | 0.0049 |
Brugia malayi | FAD binding domain containing protein | 0.0091 | 0.3638 | 0.4259 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0019 | 0.0465 | 0.0395 |
Echinococcus granulosus | NADH cytochrome b5 reductase 3 | 0.001 | 0.0073 | 0.0049 |
Plasmodium vivax | NADPH-cytochrome p450 reductase, putative | 0.0091 | 0.3638 | 1 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0043 | 0.1501 | 0.3569 |
Trichomonas vaginalis | NADPH fad oxidoreductase, putative | 0.0081 | 0.3181 | 0.8559 |
Onchocerca volvulus | Segment polarity protein dishevelled homolog | 0.0012 | 0.0126 | 0.0086 |
Brugia malayi | hypothetical protein | 0.001 | 0.0055 | 0.0064 |
Brugia malayi | Domain found in Dishevelled, Egl-10, and Pleckstrin family protein | 0.001 | 0.0055 | 0.0064 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0053 | 0.0062 |
Trichomonas vaginalis | NADPH cytochrome P450, putative | 0.0035 | 0.1154 | 0.2173 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0102 | 0.4111 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0043 | 0.1501 | 1 |
Treponema pallidum | flavodoxin | 0.0035 | 0.1154 | 1 |
Mycobacterium tuberculosis | Conserved protein | 0.0027 | 0.0811 | 0.2946 |
Chlamydia trachomatis | sulfite reductase | 0.0056 | 0.2099 | 1 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.0465 | 0.1099 |
Toxoplasma gondii | flavodoxin domain-containing protein | 0.0045 | 0.1611 | 0.6166 |
Echinococcus granulosus | segment polarity protein dishevelled | 0.0012 | 0.0126 | 0.0181 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0465 | 0.1015 |
Entamoeba histolytica | type A flavoprotein, putative | 0.0035 | 0.1154 | 0.6653 |
Mycobacterium tuberculosis | Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) | 0.0027 | 0.0811 | 0.2946 |
Loa Loa (eye worm) | flavodoxin family protein | 0.0035 | 0.1154 | 0.1351 |
Echinococcus granulosus | methionine synthase reductase | 0.0056 | 0.2099 | 0.5043 |
Brugia malayi | hypothetical protein | 0.001 | 0.0055 | 0.0064 |
Toxoplasma gondii | ferredoxin NADP+ oxidoreductase FNR | 0.001 | 0.0073 | 0.0071 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.0465 | 0.0395 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0019 | 0.0465 | 0.5 |
Brugia malayi | Domain found in Dishevelled, Egl-10, and Pleckstrin family protein | 0.0012 | 0.0126 | 0.0148 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0067 | 0.2579 | 1 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.001 | 0.0055 | 0.0005 |
Trypanosoma brucei | S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, putative | 0.0035 | 0.1154 | 0.1089 |
Trypanosoma cruzi | NADPH--cytochrome P450 reductase, putative | 0.0035 | 0.1154 | 0.1089 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.001 | 0.0055 | 0.0005 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0019 | 0.0465 | 0.3624 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0019 | 0.0465 | 0.0395 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.0465 | 0.0395 |
Echinococcus granulosus | citrate lyase subunit beta protein | 0.0027 | 0.0811 | 0.1869 |
Schistosoma mansoni | cytochrome P450 reductase | 0.0091 | 0.3638 | 0.8835 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.001 | 0.0053 | 0.0062 |
Echinococcus multilocularis | NADPH cytochrome P450 reductase | 0.0091 | 0.3638 | 0.8835 |
Entamoeba histolytica | type A flavoprotein, putative | 0.0035 | 0.1154 | 0.6653 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0102 | 0.4111 | 1 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0236 | 1 | 1 |
Plasmodium vivax | flavodoxin domain containing protein | 0.0081 | 0.3181 | 0.8717 |
Brugia malayi | ecdysteroid receptor | 0.001 | 0.0053 | 0.0062 |
Entamoeba histolytica | type A flavoprotein, putative | 0.0035 | 0.1154 | 0.6653 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.001 | 0.0053 | 0.0062 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0102 | 0.4111 | 1 |
Plasmodium falciparum | nitric oxide synthase, putative | 0.0091 | 0.3638 | 1 |
Brugia malayi | flavodoxin family protein | 0.0035 | 0.1154 | 0.1351 |
Trichomonas vaginalis | NADPH cytochrome P450, putative | 0.0035 | 0.1154 | 0.2173 |
Loa Loa (eye worm) | steroid hormone receptor | 0.001 | 0.0053 | 0.0062 |
Trypanosoma brucei | NADPH-dependent diflavin oxidoreductase 1 | 0.0091 | 0.3638 | 0.3591 |
Plasmodium falciparum | NADPH--cytochrome P450 reductase, putative | 0.0035 | 0.1154 | 0.3033 |
Echinococcus multilocularis | segment polarity protein dishevelled | 0.0012 | 0.0126 | 0.0181 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0055 | 0.0064 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0055 | 0.0064 |
Brugia malayi | nuclear hormone receptor | 0.001 | 0.0053 | 0.0062 |
Echinococcus granulosus | Pleckstrin G protein interacting region | 0.001 | 0.0055 | 0.0005 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.001 | 0.0053 | 0.0062 |
Echinococcus multilocularis | NADH cytochrome b5 reductase 3 | 0.001 | 0.0073 | 0.0049 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0043 | 0.1501 | 0.3569 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.001 | 0.0053 | 0.0062 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0102 | 0.4111 | 1 |
Brugia malayi | hypothetical protein | 0.0043 | 0.1501 | 0.1757 |
Schistosoma mansoni | z-protein (S1r protein) | 0.001 | 0.0055 | 0.0005 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0102 | 0.4111 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.001 | 0.0053 | 0.0062 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0053 | 0.0062 |
Trypanosoma cruzi | 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative | 0.0027 | 0.0811 | 0.0744 |
Echinococcus granulosus | NADPH dependent diflavin oxidoreductase 1 | 0.0091 | 0.3638 | 0.8835 |
Trypanosoma cruzi | Flavodoxin/Radical SAM superfamily/Wyosine base formation, putative | 0.0035 | 0.1154 | 0.1089 |
Loa Loa (eye worm) | FAD binding domain-containing protein | 0.0091 | 0.3638 | 0.4259 |
Loa Loa (eye worm) | DIX domain-containing protein | 0.0012 | 0.0126 | 0.0148 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0019 | 0.0465 | 0.1261 |
Entamoeba histolytica | type A flavoprotein, putative | 0.0035 | 0.1154 | 0.6653 |
Loa Loa (eye worm) | diaphorase | 0.001 | 0.0073 | 0.0085 |
Trypanosoma cruzi | Flavodoxin/Radical SAM superfamily/Wyosine base formation, putative | 0.0035 | 0.1154 | 0.1089 |
Trypanosoma cruzi | cytochrome P450 reductase, putative | 0.0091 | 0.3638 | 0.3591 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0067 | 0.2579 | 1 |
Plasmodium falciparum | S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, putative | 0.0035 | 0.1154 | 0.3033 |
Giardia lamblia | Hypothetical protein | 0.0081 | 0.3181 | 1 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0067 | 0.2579 | 0.7031 |
Mycobacterium ulcerans | hypothetical protein | 0.0027 | 0.0811 | 0.2072 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.0465 | 0.1099 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.001 | 0.0053 | 0.0062 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0019 | 0.0465 | 0.1015 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.001 | 0.0053 | 0.0062 |
Mycobacterium ulcerans | formate dehydrogenase H FdhF | 0.0091 | 0.3638 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.001 | 0.0053 | 0.0062 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0236 | 1 | 1 |
Echinococcus granulosus | NADPH cytochrome P450 reductase | 0.0091 | 0.3638 | 0.8835 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0019 | 0.0465 | 0.0544 |
Loa Loa (eye worm) | hypothetical protein | 0.0091 | 0.3638 | 0.4259 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0102 | 0.4111 | 0.4813 |
Toxoplasma gondii | flavodoxin domain-containing protein | 0.0045 | 0.1611 | 0.6166 |
Schistosoma mansoni | dishevelled | 0.0012 | 0.0126 | 0.0181 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0067 | 0.2579 | 0.6226 |
Schistosoma mansoni | dishevelled | 0.0012 | 0.0126 | 0.0181 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0043 | 0.1501 | 0.3569 |
Mycobacterium ulcerans | hypothetical protein | 0.0027 | 0.0811 | 0.2072 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0053 | 0.0062 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0067 | 0.2579 | 0.7031 |
Leishmania major | p450 reductase, putative | 0.0091 | 0.3638 | 0.3591 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.001 | 0.0053 | 0.0062 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0102 | 0.4111 | 0.4813 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.001 | 0.0053 | 0.0062 |
Brugia malayi | Cytochrome b5-like Heme/Steroid binding domain containing protein | 0.001 | 0.0073 | 0.0085 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0019 | 0.0465 | 0.1099 |
Schistosoma mansoni | NADH-cytochrome B5 reductase | 0.001 | 0.0073 | 0.0049 |
Brugia malayi | nuclear receptor NHR-88 | 0.001 | 0.0053 | 0.0062 |
Echinococcus multilocularis | segment polarity protein dishevelled | 0.0012 | 0.0126 | 0.0181 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0067 | 0.2579 | 0.7031 |
Schistosoma mansoni | regulator of G protein signaling | 0.001 | 0.0055 | 0.0005 |
Trichomonas vaginalis | NADPH cytochrome P450, putative | 0.0035 | 0.1154 | 0.2173 |
Entamoeba histolytica | hypothetical protein | 0.0043 | 0.1501 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.001 | 0.0053 | 0.0062 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0236 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.001 | 0.0053 | 0.0062 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.001 | 0.0053 | 0.0062 |
Toxoplasma gondii | exonuclease III APE | 0.0019 | 0.0465 | 0.1623 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.001 | 0.0053 | 0.0062 |
Brugia malayi | FAD binding domain containing protein | 0.0056 | 0.2099 | 0.2458 |
Loa Loa (eye worm) | hypothetical protein | 0.0203 | 0.8542 | 1 |
Mycobacterium ulcerans | citrate lyase beta subunit, CitE_2 | 0.0027 | 0.0811 | 0.2072 |
Trypanosoma brucei | NADPH-cytochrome p450 reductase, putative | 0.0091 | 0.3638 | 0.3591 |
Toxoplasma gondii | NADH-cytochrome b5 reductase 1, putative | 0.001 | 0.0073 | 0.0071 |
Trichomonas vaginalis | sulfite reductase, putative | 0.0091 | 0.3638 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.001 | 0.0053 | 0.0062 |
Trypanosoma cruzi | cytochrome P450 reductase, putative | 0.0091 | 0.3638 | 0.3591 |
Entamoeba histolytica | hypothetical protein | 0.0043 | 0.1501 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.001 | 0.0053 | 0.0062 |
Onchocerca volvulus | Rap guanine nucleotide exchange factor 1 homolog | 0.0203 | 0.8542 | 1 |
Leishmania major | NADPH-cytochrome p450 reductase-like protein | 0.0091 | 0.3638 | 0.3591 |
Trypanosoma cruzi | NADPH-dependent FMN/FAD containing oxidoreductase, putative | 0.0091 | 0.3638 | 0.3591 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0067 | 0.2579 | 0.6226 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0067 | 0.2579 | 0.2525 |
Brugia malayi | diaphorase | 0.001 | 0.0073 | 0.0085 |
Mycobacterium ulcerans | citrate (pro-3S)-lyase subunit beta | 0.0027 | 0.0811 | 0.2072 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.001 | 0.0053 | 0.0062 |
Leishmania major | hypothetical protein, conserved | 0.0035 | 0.1154 | 0.1089 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0053 | 0.0062 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0019 | 0.0465 | 0.1563 |
Onchocerca volvulus | 0.001 | 0.0073 | 0.0024 | |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0067 | 0.2579 | 0.6226 |
Brugia malayi | DIX domain containing protein | 0.0012 | 0.0126 | 0.0148 |
Onchocerca volvulus | 0.001 | 0.0055 | 0.0002 | |
Schistosoma mansoni | fyve finger-containing phosphoinositide kinase fyv1 | 0.001 | 0.0055 | 0.0005 |
Schistosoma mansoni | NADPH flavin oxidoreductase | 0.0046 | 0.1642 | 0.3916 |
Brugia malayi | N-terminal motif family protein | 0.0203 | 0.8542 | 1 |
Trypanosoma brucei | NADPH--cytochrome P450 reductase, putative | 0.0091 | 0.3638 | 0.3591 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.001 | 0.0053 | 0.0062 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0053 | 0.0062 |
Mycobacterium ulcerans | citrate (pro-3S)-lyase subunit beta | 0.0027 | 0.0811 | 0.2072 |
Entamoeba histolytica | hypothetical protein | 0.0043 | 0.1501 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0053 | 0.0062 |
Schistosoma mansoni | hypothetical protein | 0.0043 | 0.1501 | 0.3569 |
Schistosoma mansoni | diflavin oxidoreductase | 0.0045 | 0.1611 | 0.3841 |
Leishmania major | cytochrome P450 reductase, putative | 0.0081 | 0.3181 | 0.3131 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.001 | 0.0053 | 0.0062 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.001 | 0.0053 | 0.0062 |
Schistosoma mansoni | dep domain containing protein | 0.001 | 0.0055 | 0.0005 |
Trypanosoma cruzi | p450 reductase, putative | 0.0091 | 0.3638 | 0.3591 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.001 | 0.0053 | 0.0062 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0019 | 0.0465 | 0.0544 |
Loa Loa (eye worm) | FAD binding domain-containing protein | 0.0056 | 0.2099 | 0.2458 |
Echinococcus granulosus | cytochrome b5 reductase 4 | 0.001 | 0.0073 | 0.0049 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0102 | 0.4111 | 1 |
Trichomonas vaginalis | NADPH cytochrome P450, putative | 0.0035 | 0.1154 | 0.2173 |
Echinococcus multilocularis | citrate lyase subunit beta protein | 0.0027 | 0.0811 | 0.1869 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.001 | 0.0055 | 0.0005 |
Echinococcus multilocularis | NADPH dependent diflavin oxidoreductase 1 | 0.0091 | 0.3638 | 0.8835 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.001 | 0.0053 | 0.0062 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0465 | 0.1015 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Ki (binding) | = 0.042 uM | Inhibitory activity against human neuronal nitric oxide synthase (nNOS) isoenzyme. | ChEMBL. | 9667974 |
Ki (binding) | = 1.6 uM | Inhibitory activity against human inducible nitric oxide synthase (iNOS) isoenzyme. | ChEMBL. | 9667974 |
Ki (binding) | = 3 uM | Inhibitory activity against human endothelial nitric oxide synthase (eNOS) isoenzyme. | ChEMBL. | 9667974 |
Selectivity (binding) | = 38 | Selectivity of the compound for human inducible nitric oxide synthase (iNOS) and human neuronal selective nitric oxide synthase (nNOS) | ChEMBL. | 9667974 |
Selectivity (binding) | = 71 | Selectivity of the compound for human endothelial nitric oxide synthase (eNOS) and human neuronal selective nitric oxide synthase (nNOS) | ChEMBL. | 9667974 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.