Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Rattus norvegicus | GABA-A receptor; anion channel | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | ubiquitin conjugating enzyme 13 | 0.0121 | 0.3474 | 1 |
Trypanosoma cruzi | ubiquitin-conjugating enzyme E2, putative | 0.0121 | 0.3474 | 0.5 |
Brugia malayi | ubiquitin conjugating enzyme protein 13 | 0.0121 | 0.3474 | 0.7705 |
Schistosoma mansoni | matrix metallopeptidase-9 (M10 family) | 0.0081 | 0.0197 | 0.0566 |
Brugia malayi | Matrixin family protein | 0.0134 | 0.4509 | 1 |
Plasmodium vivax | ubiquitin-conjugating enzyme E2 N, putative | 0.0121 | 0.3474 | 0.5 |
Trypanosoma cruzi | ubiquitin-conjugating enzyme E2, putative | 0.0121 | 0.3474 | 0.5 |
Entamoeba histolytica | ubiquitin-conjugating enzyme family protein | 0.0121 | 0.3474 | 0.5 |
Trichomonas vaginalis | ubiquitin-conjugating enzyme E2, putative | 0.0121 | 0.3474 | 0.5 |
Leishmania major | ubiquitin-conjugating enzyme e2, putative | 0.0121 | 0.3474 | 0.5 |
Trypanosoma brucei | ubiquitin-protein ligase, putative | 0.0121 | 0.3474 | 0.5 |
Loa Loa (eye worm) | matrixin family protein | 0.0134 | 0.4509 | 1 |
Brugia malayi | Ubiquitin conjugating enzyme protein 13 | 0.0121 | 0.3474 | 0.7705 |
Loa Loa (eye worm) | matrixin family protein | 0.0123 | 0.3607 | 0.1288 |
Onchocerca volvulus | Matrilysin homolog | 0.0123 | 0.3607 | 1 |
Plasmodium falciparum | ubiquitin-conjugating enzyme E2 N, putative | 0.0121 | 0.3474 | 0.5 |
Toxoplasma gondii | ubiquitin-conjugating enzyme subfamily protein | 0.0121 | 0.3474 | 0.5 |
Onchocerca volvulus | Matrix metalloproteinase homolog | 0.0123 | 0.3607 | 1 |
Echinococcus multilocularis | matrix metallopeptidase 7 (M10 family) | 0.0201 | 1 | 1 |
Trichomonas vaginalis | ubiquitin-conjugating enzyme E2, putative | 0.0121 | 0.3474 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.