Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0087 | 0.0037 | 0.0061 |
Loa Loa (eye worm) | hypothetical protein | 0.0178 | 0.0151 | 0.0147 |
Onchocerca volvulus | Putative nachr subunit | 0.0178 | 0.0151 | 0.7789 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0178 | 0.0151 | 0.0349 |
Loa Loa (eye worm) | hypothetical protein | 0.0178 | 0.0151 | 0.0147 |
Loa Loa (eye worm) | hypothetical protein | 0.0178 | 0.0151 | 0.0147 |
Brugia malayi | K+-dependent Na+/Ca+ exchanger related-protein | 0.0204 | 0.0183 | 0.0431 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.1064 | 0.1253 | 0.3145 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta-like) | 0.0178 | 0.0151 | 0.0143 |
Loa Loa (eye worm) | phosphatidylinositol 4-kinase type 3 alpha isoform 1 | 0.0139 | 0.0101 | 0.0098 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0236 | 0.0222 | 0.0215 |
Trichomonas vaginalis | phosphatidylinositol 3-kinase class, putative | 0.0731 | 0.0839 | 0.4597 |
Schistosoma mansoni | nAChR subunit | 0.0087 | 0.0037 | 0.0029 |
Echinococcus multilocularis | nicotinic acetylcholine receptor subunit alpha 8 | 0.0178 | 0.0151 | 0.0143 |
Mycobacterium tuberculosis | Probable ionic transporter integral membrane protein ChaA | 0.0204 | 0.0183 | 0.5 |
Loa Loa (eye worm) | nicotinic acetylcholine receptor non-alpha subunit | 0.0178 | 0.0151 | 0.0147 |
Echinococcus granulosus | phosphatidylinositol 4 kinase alpha | 0.0139 | 0.0101 | 0.0094 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.0037 | 0.0033 |
Treponema pallidum | hypothetical protein | 0.0204 | 0.0183 | 0.5 |
Echinococcus granulosus | neuronal acetylcholine receptor subunit alpha 4 | 0.0178 | 0.0151 | 0.0143 |
Loa Loa (eye worm) | hypothetical protein | 0.0178 | 0.0151 | 0.0147 |
Trypanosoma cruzi | phosphatidylinositol 3-kinase 2, putative | 0.1064 | 0.1253 | 1 |
Trichomonas vaginalis | phopsphatidylinositol 3-kinase, drosophila, putative | 0.1064 | 0.1253 | 0.7184 |
Loa Loa (eye worm) | hypothetical protein | 0.0178 | 0.0151 | 0.0147 |
Loa Loa (eye worm) | hypothetical protein | 0.0204 | 0.0183 | 0.018 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0204 | 0.0183 | 0.0509 |
Loa Loa (eye worm) | hypothetical protein | 0.0178 | 0.0151 | 0.0147 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0689 | 0.0787 | 0.1962 |
Echinococcus granulosus | phosphatidylinositol 4 phosphate 3 kinase C2 | 0.0689 | 0.0787 | 0.078 |
Echinococcus multilocularis | phosphatidylinositol 4,5 bisphosphate 3 kinase | 0.1064 | 0.1253 | 0.1247 |
Schistosoma mansoni | nAChR subunit | 0.0178 | 0.0151 | 0.0143 |
Trypanosoma cruzi | phosphatidylinositol 3-kinase, putative | 0.0324 | 0.0333 | 0.2654 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0091 | 0.0043 | 0.0076 |
Brugia malayi | Cation transporter family protein | 0.0178 | 0.0151 | 0.0349 |
Loa Loa (eye worm) | hypothetical protein | 0.0178 | 0.0151 | 0.0147 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0847 | 0.0983 | 0.098 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0087 | 0.0037 | 0.0061 |
Loa Loa (eye worm) | hypothetical protein | 0.0178 | 0.0151 | 0.0147 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.0037 | 0.0033 |
Brugia malayi | hypothetical protein | 0.0087 | 0.0037 | 0.0061 |
Schistosoma mansoni | nAChR subunit | 0.0178 | 0.0151 | 0.0143 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.0037 | 0.0033 |
Loa Loa (eye worm) | hypothetical protein | 0.0178 | 0.0151 | 0.0147 |
Loa Loa (eye worm) | excitatory GABA receptor EXP-1A | 0.0178 | 0.0151 | 0.0147 |
Entamoeba histolytica | sodium/calcium exchanger protein, putative | 0.0204 | 0.0183 | 0.1159 |
Schistosoma mansoni | neurotransmitter gated ion channel | 0.0087 | 0.0037 | 0.0029 |
Loa Loa (eye worm) | ACC-1 protein | 0.0178 | 0.0151 | 0.0147 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.0037 | 0.0033 |
Echinococcus multilocularis | nicotinic acetylcholine receptor alpha subunit | 0.0178 | 0.0151 | 0.0143 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0178 | 0.0151 | 0.0143 |
Loa Loa (eye worm) | hypothetical protein | 0.0178 | 0.0151 | 0.0147 |
Echinococcus granulosus | Cys loop ligand gated ion channel subunit | 0.0087 | 0.0037 | 0.0029 |
Trichomonas vaginalis | alpha-L-fucosidase, putative | 0.1427 | 0.1705 | 1 |
Brugia malayi | Cation transporter family protein | 0.0178 | 0.0151 | 0.0349 |
Echinococcus granulosus | glycine receptor subunit beta | 0.0178 | 0.0151 | 0.0143 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.0037 | 0.0033 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0013 | 0.0009 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0099 | 0.0052 | 0.0048 |
Echinococcus multilocularis | phosphatidylinositol 4 kinase alpha | 0.0139 | 0.0101 | 0.0094 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0178 | 0.0151 | 0.0349 |
Schistosoma mansoni | transient receptor potential channel | 0.0096 | 0.0048 | 0.004 |
Schistosoma mansoni | nAChR subunit | 0.0178 | 0.0151 | 0.0143 |
Brugia malayi | acetylcholine receptor alpha subunit precursor, putative | 0.0178 | 0.0151 | 0.0349 |
Trichomonas vaginalis | phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative | 0.0356 | 0.0372 | 0.1687 |
Entamoeba histolytica | phosphatidylinositol 3-kinase 1, putative | 0.1032 | 0.1214 | 0.9676 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0178 | 0.0151 | 0.0143 |
Loa Loa (eye worm) | hypothetical protein | 0.0091 | 0.0043 | 0.0039 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0178 | 0.0151 | 0.0143 |
Echinococcus granulosus | transient receptor potential ion channel A | 0.0092 | 0.0044 | 0.0036 |
Schistosoma mansoni | neurotransmitter gated ion channel | 0.0091 | 0.0043 | 0.0035 |
Entamoeba histolytica | phosphatidylinositol 4-kinase, putative | 0.0139 | 0.0101 | 0.0485 |
Loa Loa (eye worm) | hypothetical protein | 0.0178 | 0.0151 | 0.0147 |
Schistosoma mansoni | nAChR subunit | 0.0178 | 0.0151 | 0.0143 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.0037 | 0.0033 |
Schistosoma mansoni | nicotinic acetylcholine receptor alpha | 0.0091 | 0.0043 | 0.0035 |
Brugia malayi | acetylcholine receptor, alpha-type subunit unc-38 precursor | 0.0178 | 0.0151 | 0.0349 |
Echinococcus multilocularis | phosphatidylinositol 4 phosphate 3 kinase C2 | 0.0689 | 0.0787 | 0.078 |
Plasmodium vivax | tryptophan-rich antigen (Pv-fam-a) | 0.0526 | 0.0584 | 1 |
Brugia malayi | nicotinic acetylcholine receptor alpha subunit, putative | 0.0178 | 0.0151 | 0.0349 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.0037 | 0.0033 |
Brugia malayi | hypothetical protein | 0.0087 | 0.0037 | 0.0061 |
Loa Loa (eye worm) | GABA receptor subunit | 0.0091 | 0.0043 | 0.0039 |
Schistosoma mansoni | transient receptor potential channel 4 | 0.0096 | 0.0048 | 0.004 |
Echinococcus granulosus | nicotinic acetylcholine receptor beta 1 subunit | 0.0178 | 0.0151 | 0.0143 |
Entamoeba histolytica | phosphatidylinositol 3-kinase, putative | 0.1064 | 0.1253 | 1 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0091 | 0.0043 | 0.0035 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0356 | 0.0372 | 0.091 |
Brugia malayi | acetylcholine receptor protein, alpha-like chain, putative | 0.0178 | 0.0151 | 0.0349 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0178 | 0.0151 | 0.0143 |
Schistosoma mansoni | nAChR subunit (ShAR1-alpha-like) | 0.0178 | 0.0151 | 0.0143 |
Loa Loa (eye worm) | ligand-Gated ion Channel family member | 0.0178 | 0.0151 | 0.0147 |
Brugia malayi | hypothetical protein | 0.0236 | 0.0222 | 0.0531 |
Schistosoma mansoni | hypothetical protein | 0.0204 | 0.0183 | 0.0176 |
Loa Loa (eye worm) | hypothetical protein | 0.0091 | 0.0043 | 0.0039 |
Echinococcus granulosus | sodium:potassium:calcium exchanger 6 | 0.0204 | 0.0183 | 0.0176 |
Echinococcus multilocularis | nAChR subunit | 0.0091 | 0.0043 | 0.0035 |
Echinococcus granulosus | transient receptor potential gamma protein | 0.0096 | 0.0048 | 0.004 |
Loa Loa (eye worm) | nicotinic acetylcholine receptor alpha subunit | 0.0178 | 0.0151 | 0.0147 |
Entamoeba histolytica | hypothetical protein | 0.0847 | 0.0983 | 0.7765 |
Loa Loa (eye worm) | hypothetical protein | 0.0652 | 0.0741 | 0.0738 |
Plasmodium falciparum | cation/H+ antiporter | 0.0204 | 0.0183 | 1 |
Schistosoma mansoni | nAChR subunit | 0.0087 | 0.0037 | 0.0029 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0178 | 0.0151 | 0.0349 |
Leishmania major | phosphatidylinositol 3-kinase, putative | 0.0139 | 0.0101 | 1 |
Trichomonas vaginalis | alpha-L-fucosidase, putative | 0.1427 | 0.1705 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0063 | 0.0007 | 0.0054 |
Echinococcus multilocularis | Cys loop ligand gated ion channel subunit | 0.0087 | 0.0037 | 0.0029 |
Brugia malayi | phosphatidylinositol 4-kinase, catalytic, alpha polypeptide | 0.0139 | 0.0101 | 0.0224 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0178 | 0.0151 | 0.0143 |
Loa Loa (eye worm) | hypothetical protein | 0.0178 | 0.0151 | 0.0147 |
Loa Loa (eye worm) | ACC-1 protein | 0.0178 | 0.0151 | 0.0147 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0178 | 0.0151 | 0.0143 |
Brugia malayi | glutamate-gated chloride channel alpha3A subunit, putative | 0.0087 | 0.0037 | 0.0061 |
Schistosoma mansoni | nAChR subunit | 0.0178 | 0.0151 | 0.0143 |
Trypanosoma cruzi | phosphatidylinositol 3-kinase 2, putative | 0.1064 | 0.1253 | 1 |
Onchocerca volvulus | 0.0091 | 0.0043 | 0.0405 | |
Brugia malayi | hypothetical protein | 0.0087 | 0.0037 | 0.0061 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0087 | 0.0037 | 0.0061 |
Trypanosoma cruzi | phosphatidylinositol 4-kinase alpha, putative | 0.0139 | 0.0101 | 0.0808 |
Echinococcus multilocularis | glycine receptor subunit beta | 0.0178 | 0.0151 | 0.0143 |
Echinococcus granulosus | phosphatidylinositol 45 bisphosphate 3 kinase | 0.1064 | 0.1253 | 0.1247 |
Brugia malayi | glutamate-gated chloride channel alpha3A subunit, putative | 0.0091 | 0.0043 | 0.0076 |
Schistosoma mansoni | hypothetical protein | 0.0068 | 0.0013 | 0.0005 |
Entamoeba histolytica | phosphatidylinositol 3-kinase, putative | 0.0472 | 0.0516 | 0.3911 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0099 | 0.0052 | 0.0099 |
Loa Loa (eye worm) | hypothetical protein | 0.0775 | 0.0894 | 0.0891 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.0037 | 0.0033 |
Brugia malayi | excitatory GABA receptor EXP-1A | 0.0178 | 0.0151 | 0.0349 |
Schistosoma mansoni | phosphatidylinositol 4-kinase | 0.0139 | 0.0101 | 0.0094 |
Entamoeba histolytica | phosphatidylinositol-4,5-bisphosphate 3-kinase, putative | 0.0139 | 0.0101 | 0.0485 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0091 | 0.0043 | 0.0076 |
Trichomonas vaginalis | phosphatidylinositol 3-kinase class, putative | 0.0356 | 0.0372 | 0.1687 |
Echinococcus multilocularis | acetylcholine receptor subunit beta 1 | 0.0178 | 0.0151 | 0.0143 |
Schistosoma mansoni | phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K | 0.0356 | 0.0372 | 0.0365 |
Loa Loa (eye worm) | hypothetical protein | 0.0178 | 0.0151 | 0.0147 |
Schistosoma mansoni | acetylcholine receptor subunit beta | 0.0087 | 0.0037 | 0.0029 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0063 | 0.0007 | 0.0054 |
Brugia malayi | Cation transporter family protein | 0.0178 | 0.0151 | 0.0349 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.0037 | 0.0033 |
Loa Loa (eye worm) | hypothetical protein | 0.0091 | 0.0043 | 0.0039 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0204 | 0.0183 | 0.0509 |
Trypanosoma brucei | phosphatidylinositol 3-kinase, putative | 0.0356 | 0.0372 | 1 |
Echinococcus granulosus | phosphatidylinositol 3 kinase catalytic subunit | 0.0139 | 0.0101 | 0.0094 |
Echinococcus granulosus | nAChR subunit | 0.0091 | 0.0043 | 0.0035 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.0037 | 0.0033 |
Onchocerca volvulus | Sodium\/potassium\/calcium exchanger | 0.0204 | 0.0183 | 1 |
Brugia malayi | Hypothetical glycine receptor like protein T20B12.9 in chromosome III | 0.0091 | 0.0043 | 0.0076 |
Brugia malayi | Hypothetical glycine receptor like protein T20B12.9 in chromosome III | 0.0178 | 0.0151 | 0.0349 |
Echinococcus multilocularis | nAChR subunit | 0.0178 | 0.0151 | 0.0143 |
Loa Loa (eye worm) | acetylcholine receptor alpha subunit | 0.0178 | 0.0151 | 0.0147 |
Echinococcus multilocularis | nicotinic acetylcholine receptor subunit type | 0.0087 | 0.0037 | 0.0029 |
Schistosoma mansoni | potassium-dependent sodium-calcium exchanger 3 4 | 0.0204 | 0.0183 | 0.0176 |
Onchocerca volvulus | 0.0178 | 0.0151 | 0.7789 | |
Echinococcus granulosus | nicotinic acetylcholine receptor subunit type | 0.0178 | 0.0151 | 0.0143 |
Schistosoma mansoni | nAChR subunit | 0.0178 | 0.0151 | 0.0143 |
Loa Loa (eye worm) | LGC-31 protein | 0.0178 | 0.0151 | 0.0147 |
Loa Loa (eye worm) | hypothetical protein | 0.0178 | 0.0151 | 0.0147 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.0037 | 0.0033 |
Echinococcus granulosus | nicotinic acetylcholine receptor subunit alpha 8 | 0.0178 | 0.0151 | 0.0143 |
Loa Loa (eye worm) | hypothetical protein | 0.0204 | 0.0183 | 0.018 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0063 | 0.0007 | 0.0054 |
Loa Loa (eye worm) | hypothetical protein | 0.0096 | 0.0048 | 0.0044 |
Trichomonas vaginalis | phosphatidylinositol kinase, putative | 0.0356 | 0.0372 | 0.1687 |
Brugia malayi | Sodium/calcium exchanger protein | 0.3235 | 0.3957 | 1 |
Loa Loa (eye worm) | glutamate-gated chloride channel alpha3A subunit | 0.0178 | 0.0151 | 0.0147 |
Loa Loa (eye worm) | hypothetical protein | 0.0091 | 0.0043 | 0.0039 |
Loa Loa (eye worm) | hypothetical protein | 0.0236 | 0.0222 | 0.0219 |
Schistosoma mansoni | acetylcholine receptor-related | 0.0087 | 0.0037 | 0.0029 |
Loa Loa (eye worm) | hypothetical protein | 0.0178 | 0.0151 | 0.0147 |
Echinococcus granulosus | glycine receptor subunit beta | 0.0178 | 0.0151 | 0.0143 |
Trichomonas vaginalis | phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative | 0.0731 | 0.0839 | 0.4597 |
Schistosoma mansoni | potassium-dependent sodium-calcium exchanger 3 4 | 0.0204 | 0.0183 | 0.0176 |
Schistosoma mansoni | sodium/calcium exchanger | 0.8087 | 1 | 1 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta2-like) | 0.0178 | 0.0151 | 0.0143 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0178 | 0.0151 | 0.0349 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0236 | 0.0222 | 0.0215 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.0037 | 0.0033 |
Echinococcus granulosus | nicotinic acetylcholine receptor a11 subunit | 0.0178 | 0.0151 | 0.0143 |
Echinococcus multilocularis | sodium calcium exchanger | 0.8087 | 1 | 1 |
Trypanosoma brucei | phosphatidylinositol 4-kinase alpha, putative | 0.0139 | 0.0101 | 0.2589 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0204 | 0.0183 | 0.0509 |
Echinococcus granulosus | nicotinic acetylcholine receptor alpha subunit | 0.0178 | 0.0151 | 0.0143 |
Schistosoma mansoni | phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K | 0.1064 | 0.1253 | 0.1247 |
Brugia malayi | Acetylcholine receptor protein, alpha-like chain 1 precursor | 0.0087 | 0.0037 | 0.0061 |
Loa Loa (eye worm) | hypothetical protein | 0.0091 | 0.0043 | 0.0039 |
Loa Loa (eye worm) | hypothetical protein | 0.0565 | 0.0633 | 0.063 |
Echinococcus multilocularis | nicotinic acetylcholine receptor a11 subunit | 0.0178 | 0.0151 | 0.0143 |
Echinococcus multilocularis | transient receptor potential gamma protein | 0.0096 | 0.0048 | 0.004 |
Echinococcus multilocularis | glycine receptor subunit beta | 0.0178 | 0.0151 | 0.0143 |
Echinococcus granulosus | acetylcholine receptor subunit beta 1 | 0.0178 | 0.0151 | 0.0143 |
Echinococcus multilocularis | neuronal acetylcholine receptor subunit alpha 4 | 0.0178 | 0.0151 | 0.0143 |
Loa Loa (eye worm) | hypothetical protein | 0.0689 | 0.0787 | 0.0784 |
Echinococcus multilocularis | transient receptor potential ion channel A | 0.0092 | 0.0044 | 0.0036 |
Entamoeba histolytica | phosphatidylinositol 3-kinase, putative | 0.0847 | 0.0983 | 0.7765 |
Loa Loa (eye worm) | hypothetical protein | 0.0204 | 0.0183 | 0.018 |
Echinococcus multilocularis | sodium:potassium:calcium exchanger 6 | 0.0204 | 0.0183 | 0.0176 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0178 | 0.0151 | 0.0349 |
Brugia malayi | nicotinic acetylcholine receptor beta-1 chain precursor | 0.0178 | 0.0151 | 0.0349 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0178 | 0.0151 | 0.0143 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.0037 | 0.0033 |
Entamoeba histolytica | phosphatidylinositol 3-kinase, putative | 0.0356 | 0.0372 | 0.2719 |
Onchocerca volvulus | 0.0178 | 0.0151 | 0.7789 | |
Loa Loa (eye worm) | glutamate-gated chloride channel alpha3A subunit | 0.0087 | 0.0037 | 0.0033 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0178 | 0.0151 | 0.0143 |
Schistosoma mansoni | phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K | 0.0139 | 0.0101 | 0.0094 |
Loa Loa (eye worm) | solute carrier family 8 | 0.8087 | 1 | 1 |
Trypanosoma cruzi | phosphatidylinositol 3-kinase vps34-like | 0.0356 | 0.0372 | 0.2967 |
Loa Loa (eye worm) | neuronal acetylcholine receptor protein | 0.0087 | 0.0037 | 0.0033 |
Loa Loa (eye worm) | hypothetical protein | 0.0091 | 0.0043 | 0.0039 |
Mycobacterium leprae | Probable ionic transporter integral membrane protein ChaA | 0.0204 | 0.0183 | 0.5 |
Echinococcus granulosus | sodium:potassium:calcium exchanger | 0.0204 | 0.0183 | 0.0176 |
Loa Loa (eye worm) | hypothetical protein | 0.3235 | 0.3957 | 0.3955 |
Onchocerca volvulus | 0.0178 | 0.0151 | 0.7789 | |
Echinococcus multilocularis | gamma aminobutyric acid receptor subunit | 0.0087 | 0.0037 | 0.0029 |
Onchocerca volvulus | 0.0178 | 0.0151 | 0.7789 | |
Leishmania major | phosphatidylinositol 4-kinase alpha, putative | 0.0139 | 0.0101 | 1 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0324 | 0.0333 | 0.0329 |
Loa Loa (eye worm) | hypothetical protein | 0.0099 | 0.0052 | 0.0048 |
Onchocerca volvulus | 0.0091 | 0.0043 | 0.0405 | |
Echinococcus multilocularis | nicotinic acetylcholine receptor beta 1 subunit | 0.0178 | 0.0151 | 0.0143 |
Loa Loa (eye worm) | hypothetical protein | 0.0375 | 0.0395 | 0.0392 |
Brugia malayi | gamma-aminobutyric-acid receptor beta subunit precursor | 0.0652 | 0.0741 | 0.1845 |
Toxoplasma gondii | manganese resistance 1 protein, putative | 0.0204 | 0.0183 | 1 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0063 | 0.0007 | 0.0054 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0178 | 0.0151 | 0.0349 |
Echinococcus granulosus | gamma aminobutyric acid receptor subunit | 0.0087 | 0.0037 | 0.0029 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.0037 | 0.0033 |
Plasmodium vivax | cation/H+ antiporter, putative | 0.0204 | 0.0183 | 0.1693 |
Onchocerca volvulus | 0.0178 | 0.0151 | 0.7789 | |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.0037 | 0.0033 |
Trichomonas vaginalis | phosphatidylinositol kinase, putative | 0.1064 | 0.1253 | 0.7184 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0099 | 0.0052 | 0.0099 |
Loa Loa (eye worm) | hypothetical protein | 0.0178 | 0.0151 | 0.0147 |
Echinococcus multilocularis | sodium:potassium:calcium exchanger | 0.0204 | 0.0183 | 0.0176 |
Entamoeba histolytica | phosphatidylinositol 3-kinase, putative | 0.0356 | 0.0372 | 0.2719 |
Schistosoma mansoni | nAChR subunit | 0.0178 | 0.0151 | 0.0143 |
Trichomonas vaginalis | phosphatidylinositol 3-kinase catalytic subunit gamma, putative | 0.1064 | 0.1253 | 0.7184 |
Loa Loa (eye worm) | hypothetical protein | 0.0091 | 0.0043 | 0.0039 |
Loa Loa (eye worm) | hypothetical protein | 0.0091 | 0.0043 | 0.0039 |
Loa Loa (eye worm) | acetylcholine receptor protein | 0.0087 | 0.0037 | 0.0033 |
Brugia malayi | hypothetical protein | 0.0087 | 0.0037 | 0.0061 |
Schistosoma mansoni | na/ca exchanger | 0.0204 | 0.0183 | 0.0176 |
Brugia malayi | hypothetical protein | 0.0087 | 0.0037 | 0.0061 |
Echinococcus granulosus | Cys loop ligand gated ion channel subunit | 0.0178 | 0.0151 | 0.0143 |
Echinococcus multilocularis | Cys loop ligand gated ion channel subunit | 0.0178 | 0.0151 | 0.0143 |
Loa Loa (eye worm) | hypothetical protein | 0.0178 | 0.0151 | 0.0147 |
Echinococcus granulosus | nAChR subunit | 0.0178 | 0.0151 | 0.0143 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0178 | 0.0151 | 0.0143 |
Brugia malayi | Neuronal acetylcholine receptor protein, alpha-2 chain precursor | 0.0087 | 0.0037 | 0.0061 |
Trypanosoma cruzi | phosphatidylinositol 4-kinase alpha, putative | 0.0139 | 0.0101 | 0.0808 |
Brugia malayi | Na/Ca eXchangers family member (ncx-4) | 0.0204 | 0.0183 | 0.0431 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0178 | 0.0151 | 0.0349 |
Giardia lamblia | Phosphoinositide-3-kinase, catalytic, alpha polypeptide | 0.0513 | 0.0568 | 1 |
Echinococcus multilocularis | Zinc finger, PHD finger | 0.0139 | 0.0101 | 0.0094 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0178 | 0.0151 | 0.0349 |
Loa Loa (eye worm) | Na/Ca eXchangers family member | 0.0204 | 0.0183 | 0.018 |
Schistosoma mansoni | neurotransmitter gated ion channel | 0.0087 | 0.0037 | 0.0029 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0178 | 0.0151 | 0.0349 |
Onchocerca volvulus | 0.0178 | 0.0151 | 0.7789 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
GI50 (functional) | -5.462 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.462 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.348 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.321 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HOP-92 Non-Small Cell Lung cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.319 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.286 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.