Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0054 | 0.0366 | 0.0366 |
Plasmodium vivax | serine/threonine protein kinase 6, putative | 0.0126 | 0.3086 | 1 |
Echinococcus multilocularis | serine threonine protein kinase nrc serine threonine protein kinase gad | 0.0117 | 0.2769 | 0.2778 |
Trichomonas vaginalis | AGC family protein kinase | 0.0126 | 0.3086 | 0.3369 |
Schistosoma mansoni | serine/threonine kinase | 0.0062 | 0.0663 | 0.0663 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0054 | 0.0366 | 0.0366 |
Schistosoma mansoni | amine GPCR | 0.0054 | 0.0366 | 0.0366 |
Trichomonas vaginalis | AGC family protein kinase | 0.0204 | 0.6058 | 0.714 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0054 | 0.0366 | 0.0366 |
Onchocerca volvulus | 0.0054 | 0.0366 | 0.5 | |
Schistosoma mansoni | serine/threonine protein kinase | 0.0062 | 0.0663 | 0.0663 |
Trichomonas vaginalis | AGC family protein kinase | 0.0204 | 0.6058 | 0.714 |
Brugia malayi | p70 ribosomal S6 kinase beta | 0.0175 | 0.4961 | 0.5312 |
Loa Loa (eye worm) | hypothetical protein | 0.0062 | 0.0663 | 0.0344 |
Onchocerca volvulus | 0.0054 | 0.0366 | 0.5 | |
Loa Loa (eye worm) | AUR protein kinase | 0.0126 | 0.3086 | 0.3145 |
Schistosoma mansoni | myosin xvIII | 0.0054 | 0.0366 | 0.0366 |
Entamoeba histolytica | protein kinase, putative | 0.0175 | 0.4961 | 0.7966 |
Echinococcus multilocularis | ribosomal protein S6 kinase alpha 3 | 0.0062 | 0.0663 | 0.0344 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0054 | 0.0366 | 0.0366 |
Loa Loa (eye worm) | AGC/PDK1 protein kinase | 0.0204 | 0.6058 | 0.658 |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.0054 | 0.0366 | 0.5 |
Echinococcus granulosus | ribosomal protein S6 kinase alpha 3 | 0.0062 | 0.0663 | 0.0344 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.0054 | 0.0366 | 0.0366 |
Echinococcus granulosus | calcium:calmodulin dependent protein kinase | 0.0117 | 0.2769 | 0.2778 |
Loa Loa (eye worm) | AGC/AKT protein kinase | 0.0175 | 0.4961 | 0.5312 |
Schistosoma mansoni | opsin-like receptor | 0.0054 | 0.0366 | 0.0366 |
Entamoeba histolytica | protein kinase, putative | 0.0204 | 0.6058 | 1 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0054 | 0.0366 | 0.0366 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0062 | 0.0663 | 0.0663 |
Plasmodium falciparum | serine/threonine protein kinase, putative | 0.0126 | 0.3086 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0204 | 0.6058 | 0.6058 |
Echinococcus granulosus | Ribosomal protein S6 kinase beta 2 | 0.0062 | 0.0663 | 0.0344 |
Echinococcus granulosus | serine:threonine protein kinase N2 | 0.0062 | 0.0663 | 0.0344 |
Onchocerca volvulus | 0.0054 | 0.0366 | 0.5 | |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.0054 | 0.0366 | 0.5 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0082 | 0.1414 | 0.1414 |
Onchocerca volvulus | 0.0054 | 0.0366 | 0.5 | |
Loa Loa (eye worm) | AGC/NDR protein kinase | 0.0062 | 0.0663 | 0.0344 |
Echinococcus granulosus | ribosomal protein s6 kinase beta 1 | 0.0062 | 0.0663 | 0.0344 |
Trichomonas vaginalis | AGC family protein kinase | 0.0062 | 0.0663 | 0.0296 |
Echinococcus granulosus | serine/threonine protein kinase | 0.0117 | 0.2769 | 0.2778 |
Echinococcus multilocularis | protein kinase c epsilon type | 0.0062 | 0.0663 | 0.0344 |
Echinococcus multilocularis | hyperpolarization activated cyclic | 0.0056 | 0.043 | 0.0075 |
Onchocerca volvulus | 0.0054 | 0.0366 | 0.5 | |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0082 | 0.1414 | 0.1211 |
Onchocerca volvulus | 0.0054 | 0.0366 | 0.5 | |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0054 | 0.0366 | 0.0366 |
Trichomonas vaginalis | AGC family protein kinase | 0.0175 | 0.4961 | 0.5748 |
Echinococcus multilocularis | serine:threonine protein kinase 12 B | 0.0126 | 0.3086 | 0.3145 |
Brugia malayi | Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog | 0.0282 | 0.9017 | 1 |
Echinococcus multilocularis | cyclic nucleotide gated cation channel | 0.0056 | 0.043 | 0.0075 |
Schistosoma mansoni | opsin-like receptor | 0.0054 | 0.0366 | 0.0366 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0054 | 0.0366 | 0.0366 |
Entamoeba histolytica | protein kinase, putative | 0.0126 | 0.3086 | 0.4491 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.0282 | 0.9017 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0062 | 0.0663 | 0.0296 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0054 | 0.0366 | 0.0366 |
Brugia malayi | protein kinase C II. | 0.0062 | 0.0663 | 0.0344 |
Loa Loa (eye worm) | AUR protein kinase | 0.0126 | 0.3086 | 0.3145 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0264 | 0.8312 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0054 | 0.0366 | 0.0366 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0082 | 0.1414 | 0.1414 |
Trichomonas vaginalis | AGC family protein kinase | 0.0062 | 0.0663 | 0.0296 |
Loa Loa (eye worm) | AGC/RSK/RSK protein kinase | 0.0062 | 0.0663 | 0.0344 |
Brugia malayi | serine/threonine kinase 12 | 0.0126 | 0.3086 | 0.3145 |
Trichomonas vaginalis | serine/threonine-protein kinase sgk, putative | 0.0058 | 0.0505 | 0.0094 |
Schistosoma mansoni | biogenic amine receptor | 0.0054 | 0.0366 | 0.0366 |
Brugia malayi | Protein kinase domain containing protein | 0.0062 | 0.0663 | 0.0344 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0054 | 0.0366 | 0.0366 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0062 | 0.0663 | 0.0663 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0062 | 0.0663 | 0.0663 |
Schistosoma mansoni | serine/threonine-protein kinase | 0.0117 | 0.2769 | 0.2769 |
Brugia malayi | Cyclic-nucleotide gated cation channel | 0.0056 | 0.043 | 0.0075 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0054 | 0.0366 | 0.0366 |
Echinococcus multilocularis | cyclic nucleotide gated cation channel alpha 3 | 0.0056 | 0.043 | 0.0075 |
Brugia malayi | Protein kinase domain containing protein | 0.0062 | 0.0663 | 0.0344 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0056 | 0.043 | 0.043 |
Echinococcus multilocularis | Protein kinase C, brain isozyme | 0.0062 | 0.0663 | 0.0344 |
Leishmania major | protein kinase, putative | 0.0126 | 0.3086 | 0.5 |
Echinococcus multilocularis | potassium:sodium hyperpolarization activated | 0.0056 | 0.043 | 0.0075 |
Loa Loa (eye worm) | AUR protein kinase | 0.0126 | 0.3086 | 0.3145 |
Echinococcus granulosus | Protein kinase C brain isozyme | 0.0062 | 0.0663 | 0.0344 |
Schistosoma mansoni | neuropeptide receptor | 0.0054 | 0.0366 | 0.0366 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0054 | 0.0366 | 0.0366 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0054 | 0.0366 | 0.0366 |
Echinococcus multilocularis | protein kinase c iota type | 0.0062 | 0.0663 | 0.0344 |
Schistosoma mansoni | amine GPCR | 0.0054 | 0.0366 | 0.0366 |
Brugia malayi | serine/threonine-protein kinase 6 | 0.0126 | 0.3086 | 0.3145 |
Entamoeba histolytica | serine/threonine- protein kinase 6 , putative | 0.0126 | 0.3086 | 0.4491 |
Onchocerca volvulus | 0.0054 | 0.0366 | 0.5 | |
Schistosoma mansoni | adenoreceptor | 0.0054 | 0.0366 | 0.0366 |
Brugia malayi | Protein kinase domain containing protein | 0.0175 | 0.4961 | 0.5312 |
Echinococcus multilocularis | voltage gated potassium channel | 0.0082 | 0.1414 | 0.1211 |
Brugia malayi | phosphoinositide-dependent protein kinase I | 0.0204 | 0.6058 | 0.658 |
Echinococcus multilocularis | hyperpolarization activated cyclic | 0.0056 | 0.043 | 0.0075 |
Trichomonas vaginalis | AGC family protein kinase | 0.0126 | 0.3086 | 0.3369 |
Schistosoma mansoni | amine GPCR | 0.0054 | 0.0366 | 0.0366 |
Echinococcus multilocularis | nervana 2 | 0.0113 | 0.261 | 0.2594 |
Echinococcus granulosus | sodium:potassium dependent atpase beta subunit | 0.0113 | 0.261 | 0.2594 |
Echinococcus multilocularis | serine:threonine protein kinase 38 | 0.0062 | 0.0663 | 0.0344 |
Trichomonas vaginalis | AGC family protein kinase | 0.0175 | 0.4961 | 0.5748 |
Trichomonas vaginalis | AGC family protein kinase | 0.0175 | 0.4961 | 0.5748 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0062 | 0.0663 | 0.0663 |
Entamoeba histolytica | serine/threonine protein kinase 6, putative | 0.0126 | 0.3086 | 0.4491 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.0054 | 0.0366 | 0.0366 |
Echinococcus granulosus | serine:threonine protein kinase 12 B | 0.0126 | 0.3086 | 0.3145 |
Echinococcus granulosus | cyclic nucleotide gated cation channel | 0.0056 | 0.043 | 0.0075 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0282 | 0.9017 | 1 |
Onchocerca volvulus | 0.0054 | 0.0366 | 0.5 | |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0054 | 0.0366 | 0.0366 |
Trypanosoma brucei | rac serine-threonine kinase, putative | 0.0175 | 0.4961 | 1 |
Loa Loa (eye worm) | AGC/RSK/P70 protein kinase | 0.0175 | 0.4961 | 0.5312 |
Trichomonas vaginalis | AGC family protein kinase | 0.0062 | 0.0663 | 0.0296 |
Schistosoma mansoni | hyperpolarization activated cyclic nucleotide-gated potassium channel | 0.0056 | 0.043 | 0.043 |
Brugia malayi | Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog | 0.0082 | 0.1414 | 0.1211 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0054 | 0.0366 | 0.0366 |
Loa Loa (eye worm) | cyclic-nucleotide gated cation channel | 0.0056 | 0.043 | 0.0075 |
Schistosoma mansoni | neuropeptide receptor | 0.0054 | 0.0366 | 0.0366 |
Echinococcus granulosus | aurora kinase A | 0.0126 | 0.3086 | 0.3145 |
Loa Loa (eye worm) | AGC/PKN protein kinase | 0.0062 | 0.0663 | 0.0344 |
Echinococcus granulosus | potassium:sodium hyperpolarization activated | 0.0056 | 0.043 | 0.0075 |
Schistosoma mansoni | amine GPCR | 0.0054 | 0.0366 | 0.0366 |
Trichomonas vaginalis | AGC family protein kinase | 0.0175 | 0.4961 | 0.5748 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0054 | 0.0366 | 0.0366 |
Trichomonas vaginalis | AGC family protein kinase | 0.0175 | 0.4961 | 0.5748 |
Schistosoma mansoni | biogenic amine receptor | 0.0054 | 0.0366 | 0.0366 |
Echinococcus multilocularis | aurora kinase A | 0.0126 | 0.3086 | 0.3145 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.1414 | 0.1211 |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.0117 | 0.2769 | 0.3903 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0054 | 0.0366 | 0.0366 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0082 | 0.1414 | 0.1211 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0062 | 0.0663 | 0.0663 |
Echinococcus granulosus | voltage gated potassium channel | 0.0082 | 0.1414 | 0.1211 |
Schistosoma mansoni | hyperpolarization activated cyclic nucleotide-gated potassium channel | 0.0056 | 0.043 | 0.043 |
Loa Loa (eye worm) | cyclic-nucleotide gated cation channel | 0.0056 | 0.043 | 0.0075 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0054 | 0.0366 | 0.0366 |
Schistosoma mansoni | hypothetical protein | 0.0054 | 0.0366 | 0.0366 |
Toxoplasma gondii | AGC kinase | 0.0175 | 0.4961 | 1 |
Echinococcus granulosus | hyperpolarization activated cyclic | 0.0056 | 0.043 | 0.0075 |
Echinococcus granulosus | hyperpolarization activated cyclic | 0.0056 | 0.043 | 0.0075 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0054 | 0.0366 | 0.0366 |
Echinococcus granulosus | 3-phosphoinositide-dependent protein kinase 1 | 0.0204 | 0.6058 | 0.658 |
Trichomonas vaginalis | AGC family protein kinase | 0.0204 | 0.6058 | 0.714 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0282 | 0.9017 | 1 |
Onchocerca volvulus | 0.0054 | 0.0366 | 0.5 | |
Trichomonas vaginalis | AGC family protein kinase | 0.0126 | 0.3086 | 0.3369 |
Schistosoma mansoni | cyclic-nucleotide-gated cation channel | 0.0056 | 0.043 | 0.043 |
Schistosoma mansoni | cyclic-nucleotide-gated cation channel | 0.0056 | 0.043 | 0.043 |
Brugia malayi | Hr1 repeat family protein | 0.0062 | 0.0663 | 0.0344 |
Entamoeba histolytica | protein kinase , putative | 0.0126 | 0.3086 | 0.4491 |
Echinococcus multilocularis | Ribosomal protein S6 kinase beta 2 | 0.0062 | 0.0663 | 0.0344 |
Onchocerca volvulus | 0.0054 | 0.0366 | 0.5 | |
Giardia lamblia | Aurora kinase | 0.0126 | 0.3086 | 1 |
Echinococcus multilocularis | ribosomal protein s6 kinase beta 1 | 0.0062 | 0.0663 | 0.0344 |
Schistosoma mansoni | amine GPCR | 0.0054 | 0.0366 | 0.0366 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0054 | 0.0366 | 0.0366 |
Loa Loa (eye worm) | hypothetical protein | 0.0245 | 0.7603 | 0.8366 |
Trypanosoma cruzi | aurora B kinase, putative | 0.0126 | 0.3086 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.0175 | 0.4961 | 0.7966 |
Onchocerca volvulus | 0.0054 | 0.0366 | 0.5 | |
Onchocerca volvulus | 0.0054 | 0.0366 | 0.5 | |
Schistosoma mansoni | neuropeptide receptor | 0.0054 | 0.0366 | 0.0366 |
Schistosoma mansoni | hypothetical protein | 0.0054 | 0.0366 | 0.0366 |
Schistosoma mansoni | atypical protein kinase C | 0.0062 | 0.0663 | 0.0663 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.043 | 0.0075 |
Onchocerca volvulus | 0.0054 | 0.0366 | 0.5 | |
Echinococcus granulosus | nervana 2 | 0.0113 | 0.261 | 0.2594 |
Echinococcus multilocularis | serine threonine protein kinase | 0.0062 | 0.0663 | 0.0344 |
Echinococcus multilocularis | serine:threonine protein kinase N2 | 0.0062 | 0.0663 | 0.0344 |
Echinococcus granulosus | cyclic nucleotide gated cation channel alpha 3 | 0.0056 | 0.043 | 0.0075 |
Loa Loa (eye worm) | AGC/PKC/ETA protein kinase | 0.0062 | 0.0663 | 0.0344 |
Onchocerca volvulus | 0.0054 | 0.0366 | 0.5 | |
Entamoeba histolytica | protein kinase, putative | 0.0175 | 0.4961 | 0.7966 |
Echinococcus multilocularis | rac serine:threonine kinase | 0.0117 | 0.2769 | 0.2778 |
Trichomonas vaginalis | AGC family protein kinase | 0.0175 | 0.4961 | 0.5748 |
Onchocerca volvulus | 0.0054 | 0.0366 | 0.5 | |
Echinococcus multilocularis | nervana 2 | 0.0113 | 0.261 | 0.2594 |
Schistosoma mansoni | neuropeptide receptor | 0.0054 | 0.0366 | 0.0366 |
Echinococcus multilocularis | serine:threonine protein kinase N2 | 0.0062 | 0.0663 | 0.0344 |
Schistosoma mansoni | serine/threonine-protein kinase | 0.0117 | 0.2769 | 0.2769 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0054 | 0.0366 | 0.0366 |
Echinococcus granulosus | protein kinase c iota type | 0.0062 | 0.0663 | 0.0344 |
Brugia malayi | serine/threonine protein kinase 6 | 0.0126 | 0.3086 | 0.3145 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0126 | 0.3086 | 0.3086 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0054 | 0.0366 | 0.0366 |
Echinococcus multilocularis | 3 phosphoinositide dependent protein kinase 1 | 0.0204 | 0.6058 | 0.658 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0054 | 0.0366 | 0.0366 |
Schistosoma mansoni | hypothetical protein | 0.0054 | 0.0366 | 0.0366 |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.0117 | 0.2769 | 0.3903 |
Echinococcus granulosus | nervana 2 | 0.0113 | 0.261 | 0.2594 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0054 | 0.0366 | 0.0366 |
Schistosoma mansoni | protein kinase | 0.0126 | 0.3086 | 0.3086 |
Schistosoma mansoni | biogenic amine receptor | 0.0054 | 0.0366 | 0.0366 |
Loa Loa (eye worm) | AGC/DMPK/GEK protein kinase | 0.0062 | 0.0663 | 0.0344 |
Echinococcus multilocularis | sodium:potassium dependent atpase beta subunit | 0.0113 | 0.261 | 0.2594 |
Brugia malayi | Protein kinase domain containing protein | 0.0204 | 0.6058 | 0.658 |
Echinococcus multilocularis | Glutaredoxin protein 5 | 0.0113 | 0.261 | 0.2594 |
Echinococcus granulosus | NDR protein kinase | 0.0062 | 0.0663 | 0.0344 |
Trichomonas vaginalis | AGC family protein kinase | 0.0175 | 0.4961 | 0.5748 |
Echinococcus granulosus | protein kinase C gamma type | 0.0062 | 0.0663 | 0.0344 |
Loa Loa (eye worm) | AGC/RSK/MSK protein kinase | 0.0062 | 0.0663 | 0.0344 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0062 | 0.0663 | 0.0663 |
Entamoeba histolytica | protein kinase, putative | 0.0126 | 0.3086 | 0.4491 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0054 | 0.0366 | 0.0366 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0126 | 0.3086 | 0.4491 |
Entamoeba histolytica | serine/threonine- protein kinase 6, putative | 0.0126 | 0.3086 | 0.4491 |
Echinococcus granulosus | Glutaredoxin protein 5 | 0.0113 | 0.261 | 0.2594 |
Trichomonas vaginalis | AGC family protein kinase | 0.0126 | 0.3086 | 0.3369 |
Schistosoma mansoni | histamine h1 receptor | 0.0054 | 0.0366 | 0.0366 |
Schistosoma mansoni | opsin-like receptor | 0.0054 | 0.0366 | 0.0366 |
Onchocerca volvulus | 0.0054 | 0.0366 | 0.5 | |
Loa Loa (eye worm) | AGC/PDK1 protein kinase | 0.0204 | 0.6058 | 0.658 |
Echinococcus granulosus | cyclic nucleotide gated cation channel | 0.0056 | 0.043 | 0.0075 |
Onchocerca volvulus | 0.0054 | 0.0366 | 0.5 | |
Entamoeba histolytica | protein kinase 2, putative | 0.0117 | 0.2769 | 0.3903 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0264 | 0.8312 | 1 |
Schistosoma mansoni | cyclic-nucleotide-gated cation channel | 0.0056 | 0.043 | 0.043 |
Echinococcus granulosus | protein kinase c epsilon type | 0.0062 | 0.0663 | 0.0344 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0054 | 0.0366 | 0.0366 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0054 | 0.0366 | 0.0366 |
Echinococcus granulosus | serine threonine protein kinase nrc | 0.0117 | 0.2769 | 0.2778 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0054 | 0.0366 | 0.0366 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
GI50 (functional) | -5.841 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-5 Melanoma cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.815 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the DU-145 Prostate cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.671 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.531 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.467 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HOP-92 Non-Small Cell Lung cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.385 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.348 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.028 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MDA-N Breast cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.929 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.826 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MALME-3M Melanoma cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.779 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.