Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0205 | 0.021 | 0.021 |
Echinococcus granulosus | sodium:potassium:calcium exchanger 6 | 0.0205 | 0.021 | 0.021 |
Schistosoma mansoni | alpha-glucosidase | 0.0136 | 0.0125 | 0.0125 |
Treponema pallidum | hypothetical protein | 0.0205 | 0.021 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0164 | 0.016 | 0.016 |
Schistosoma mansoni | hypothetical protein | 0.0205 | 0.021 | 0.021 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0205 | 0.021 | 0.1216 |
Loa Loa (eye worm) | solute carrier family 8 | 0.8134 | 1 | 1 |
Loa Loa (eye worm) | Na/Ca eXchangers family member | 0.0205 | 0.021 | 0.021 |
Loa Loa (eye worm) | hypothetical protein | 0.3254 | 0.3974 | 0.3974 |
Schistosoma mansoni | alpha-glucosidase | 0.0136 | 0.0125 | 0.0125 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0158 | 0.0152 | 0.0152 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0158 | 0.0152 | 0.0152 |
Trypanosoma brucei | glucosidase, putative | 0.0035 | 0 | 0.5 |
Mycobacterium tuberculosis | Probable ionic transporter integral membrane protein ChaA | 0.0205 | 0.021 | 0.5 |
Plasmodium vivax | cation/H+ antiporter, putative | 0.0205 | 0.021 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0205 | 0.021 | 0.021 |
Schistosoma mansoni | na/ca exchanger | 0.0205 | 0.021 | 0.021 |
Loa Loa (eye worm) | hypothetical protein | 0.0205 | 0.021 | 0.021 |
Mycobacterium leprae | Probable ionic transporter integral membrane protein ChaA | 0.0205 | 0.021 | 0.5 |
Echinococcus multilocularis | sodium:potassium:calcium exchanger | 0.0205 | 0.021 | 0.021 |
Schistosoma mansoni | potassium-dependent sodium-calcium exchanger 3 4 | 0.0205 | 0.021 | 0.021 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0035 | 0 | 0.5 |
Schistosoma mansoni | potassium-dependent sodium-calcium exchanger 3 4 | 0.0205 | 0.021 | 0.021 |
Echinococcus granulosus | geminin | 0.0164 | 0.016 | 0.016 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0035 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0175 | 0.0173 | 0.0173 |
Brugia malayi | K+-dependent Na+/Ca+ exchanger related-protein | 0.0205 | 0.021 | 0.0529 |
Onchocerca volvulus | Sodium\/potassium\/calcium exchanger | 0.0205 | 0.021 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0205 | 0.021 | 0.1216 |
Onchocerca volvulus | Rap guanine nucleotide exchange factor 1 homolog | 0.0175 | 0.0173 | 0.7347 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0158 | 0.0152 | 0.0152 |
Schistosoma mansoni | hypothetical protein | 0.0164 | 0.016 | 0.016 |
Echinococcus granulosus | sodium:potassium:calcium exchanger | 0.0205 | 0.021 | 0.021 |
Brugia malayi | Na/Ca eXchangers family member (ncx-4) | 0.0205 | 0.021 | 0.0529 |
Brugia malayi | N-terminal motif family protein | 0.0175 | 0.0173 | 0.0435 |
Trichomonas vaginalis | alpha-L-fucosidase, putative | 0.1435 | 0.1728 | 1 |
Echinococcus multilocularis | geminin | 0.0164 | 0.016 | 0.016 |
Schistosoma mansoni | sodium/calcium exchanger | 0.8134 | 1 | 1 |
Echinococcus multilocularis | sodium calcium exchanger | 0.8134 | 1 | 1 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0158 | 0.0152 | 0.0152 |
Brugia malayi | Sodium/calcium exchanger protein | 0.3254 | 0.3974 | 1 |
Plasmodium falciparum | cation/H+ antiporter | 0.0205 | 0.021 | 0.5 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0158 | 0.0152 | 0.0382 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0035 | 0 | 0.5 |
Trichomonas vaginalis | alpha-L-fucosidase, putative | 0.1435 | 0.1728 | 1 |
Toxoplasma gondii | manganese resistance 1 protein, putative | 0.0205 | 0.021 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0205 | 0.021 | 0.1216 |
Echinococcus multilocularis | sodium:potassium:calcium exchanger 6 | 0.0205 | 0.021 | 0.021 |
Entamoeba histolytica | sodium/calcium exchanger protein, putative | 0.0205 | 0.021 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.