Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Rattus norvegicus | Vanilloid receptor | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.051 | 0.1555 | 1 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.051 | 0.1555 | 0.1173 |
Plasmodium vivax | hypothetical protein, conserved | 0.051 | 0.1555 | 0.5 |
Onchocerca volvulus | 0.051 | 0.1555 | 0.5 | |
Toxoplasma gondii | ABC1 family protein | 0.051 | 0.1555 | 0.5 |
Echinococcus multilocularis | short transient receptor potential channel 6 | 0.0004 | 0.0001 | 0.0006 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.051 | 0.1555 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.051 | 0.1555 | 0.5 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.051 | 0.1555 | 0.1173 |
Mycobacterium ulcerans | beta-lactamase | 0.051 | 0.1555 | 0.2105 |
Mycobacterium tuberculosis | Conserved protein | 0.051 | 0.1555 | 0.1173 |
Mycobacterium tuberculosis | Probable hydrolase | 0.051 | 0.1555 | 0.1173 |
Wolbachia endosymbiont of Brugia malayi | cell division protein FtsI | 0.0145 | 0.0433 | 0.5 |
Mycobacterium tuberculosis | Class a beta-lactamase BlaC | 0.188 | 0.5764 | 0.5573 |
Brugia malayi | beta-lactamase | 0.051 | 0.1555 | 1 |
Mycobacterium leprae | PROBABLE CONSERVED LIPOPROTEIN LPQF | 0.0902 | 0.2761 | 1 |
Schistosoma mansoni | transient receptor potential channel | 0.0004 | 0.0001 | 0.0006 |
Echinococcus multilocularis | transient receptor potential cation channel | 0.0004 | 0.0001 | 0.0006 |
Mycobacterium tuberculosis | Conserved protein | 0.051 | 0.1555 | 0.1173 |
Chlamydia trachomatis | transglycolase/transpeptidase | 0.0145 | 0.0433 | 0.5 |
Echinococcus granulosus | transient receptor potential cation channel | 0.0004 | 0.0001 | 0.0006 |
Loa Loa (eye worm) | hypothetical protein | 0.051 | 0.1555 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.051 | 0.1555 | 0.2105 |
Loa Loa (eye worm) | beta-lactamase | 0.051 | 0.1555 | 1 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.051 | 0.1555 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0004 | 0.0001 | 0.0006 |
Mycobacterium leprae | conserved hypothetical protein | 0.051 | 0.1555 | 0.4822 |
Onchocerca volvulus | 0.051 | 0.1555 | 0.5 | |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.051 | 0.1555 | 1 |
Treponema pallidum | penicillin-binding protein (pbp-1) | 0.0145 | 0.0433 | 0.5 |
Mycobacterium tuberculosis | Conserved protein | 0.051 | 0.1555 | 0.1173 |
Brugia malayi | beta-lactamase family protein | 0.051 | 0.1555 | 1 |
Echinococcus multilocularis | transient receptor potential cation channel | 0.0004 | 0.0001 | 0.0006 |
Trypanosoma brucei | beta lactamase | 0.0902 | 0.2761 | 1 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.051 | 0.1555 | 0.1173 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.051 | 0.1555 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.051 | 0.1555 | 0.5 |
Brugia malayi | beta-lactamase family protein | 0.051 | 0.1555 | 1 |
Mycobacterium tuberculosis | Probable conserved lipoprotein LpqF | 0.0902 | 0.2761 | 0.2433 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.051 | 0.1555 | 0.1173 |
Chlamydia trachomatis | transglycolase/transpeptidase | 0.0145 | 0.0433 | 0.5 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.051 | 0.1555 | 1 |
Mycobacterium ulcerans | class a beta-lactamase, BlaC | 0.188 | 0.5764 | 1 |
Treponema pallidum | penicillin-binding protein (pbp-2) | 0.0145 | 0.0433 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.051 | 0.1555 | 1 |
Echinococcus granulosus | short transient receptor potential channel 6 | 0.0004 | 0.0001 | 0.0006 |
Mycobacterium ulcerans | lipoprotein LpqF | 0.0902 | 0.2761 | 0.4366 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.051 | 0.1555 | 1 |
Onchocerca volvulus | 0.051 | 0.1555 | 0.5 | |
Trichomonas vaginalis | esterase, putative | 0.051 | 0.1555 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.051 | 0.1555 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.051 | 0.1555 | 1 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.051 | 0.1555 | 1 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.051 | 0.1555 | 0.2105 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.051 | 0.1555 | 0.1173 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.051 | 0.1555 | 1 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.051 | 0.1555 | 1 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.051 | 0.1555 | 1 |
Treponema pallidum | penicillin-binding protein (pbp-3) | 0.0145 | 0.0433 | 0.5 |
Mycobacterium leprae | Probable lipase LipE | 0.051 | 0.1555 | 0.4822 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.051 | 0.1555 | 1 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.051 | 0.1555 | 0.1173 |
Leishmania major | hypothetical protein, conserved | 0.051 | 0.1555 | 0.5 |
Mycobacterium ulcerans | lipase LipD | 0.051 | 0.1555 | 0.2105 |
Loa Loa (eye worm) | hypothetical protein | 0.051 | 0.1555 | 1 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.051 | 0.1555 | 0.2105 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.