Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | cysteine protease, putative | 0.0337 | 0.2216 | 0.4054 |
Entamoeba histolytica | cysteine protease, putative | 0.0337 | 0.2216 | 0.4054 |
Entamoeba histolytica | cysteine protease, putative | 0.0337 | 0.2216 | 0.4054 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0628 | 0.5467 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Toxoplasma gondii | cathepsin B | 0.0415 | 0.3093 | 0.5658 |
Onchocerca volvulus | 0.0628 | 0.5467 | 1 | |
Plasmodium vivax | vivapain-2 | 0.0628 | 0.5467 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0337 | 0.2216 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Schistosoma mansoni | cathepsin s | 0.0198 | 0.067 | 0.067 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0628 | 0.5467 | 0.5467 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.0337 | 0.2216 | 0.2216 |
Entamoeba histolytica | cysteine proteinase 2 | 0.0337 | 0.2216 | 0.4054 |
Onchocerca volvulus | Cathepsin F homolog | 0.0628 | 0.5467 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0429 | 0.325 | 0.325 |
Brugia malayi | Cathepsin L-like precursor | 0.0628 | 0.5467 | 0.5467 |
Leishmania major | cathepsin L-like protease | 0.0628 | 0.5467 | 1 |
Echinococcus multilocularis | cathepsin L | 0.0337 | 0.2216 | 0.2216 |
Leishmania major | cathepsin L-like protease | 0.0628 | 0.5467 | 1 |
Echinococcus multilocularis | cathepsin b | 0.1034 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0628 | 0.5467 | 0.5467 |
Echinococcus multilocularis | cathepsin b | 0.1034 | 1 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0628 | 0.5467 | 0.5467 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Brugia malayi | cathepsin F-like cysteine proteinase | 0.0198 | 0.067 | 0.067 |
Loa Loa (eye worm) | cathepsin B | 0.0415 | 0.3093 | 0.3093 |
Brugia malayi | Cathepsin L-like precursor | 0.0429 | 0.325 | 0.325 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0337 | 0.2216 | 0.4054 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0628 | 0.5467 | 0.5467 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0337 | 0.2216 | 0.4054 |
Onchocerca volvulus | 0.0628 | 0.5467 | 1 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0628 | 0.5467 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0628 | 0.5467 | 0.5467 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0337 | 0.2216 | 0.2216 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0337 | 0.2216 | 0.2216 |
Brugia malayi | cathepsin L-like precursor | 0.0429 | 0.325 | 0.325 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Echinococcus granulosus | cathepsin b | 0.1034 | 1 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 1 | 0.0337 | 0.2216 | 0.4054 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.1034 | 1 | 1 |
Plasmodium vivax | vivapain-1 | 0.0337 | 0.2216 | 0.4054 |
Entamoeba histolytica | cysteine protease, putative | 0.0337 | 0.2216 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0337 | 0.2216 | 0.4054 |
Brugia malayi | cathepsin L-like cysteine proteinase, identical | 0.0198 | 0.067 | 0.067 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0628 | 0.5467 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0415 | 0.3093 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0628 | 0.5467 | 0.5467 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0429 | 0.325 | 0.325 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0198 | 0.067 | 0.067 |
Giardia lamblia | Cathepsin B precursor | 0.0415 | 0.3093 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0337 | 0.2216 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0628 | 0.5467 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0628 | 0.5467 | 1 |
Onchocerca volvulus | 0.0628 | 0.5467 | 1 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0628 | 0.5467 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0429 | 0.325 | 0.5946 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0628 | 0.5467 | 0.5467 |
Loa Loa (eye worm) | fibroinase | 0.0628 | 0.5467 | 0.5467 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0628 | 0.5467 | 0.5467 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0628 | 0.5467 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0628 | 0.5467 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0415 | 0.3093 | 0.3093 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0415 | 0.3093 | 0.2697 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0628 | 0.5467 | 1 |
Onchocerca volvulus | 0.0628 | 0.5467 | 1 | |
Leishmania major | cathepsin L-like protease | 0.0628 | 0.5467 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0415 | 0.3093 | 0.5658 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0628 | 0.5467 | 0.5467 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0628 | 0.5467 | 0.5467 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0628 | 0.5467 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0628 | 0.5467 | 0.5467 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0628 | 0.5467 | 1 |
Echinococcus granulosus | cathepsin L cysteine protease | 0.0337 | 0.2216 | 0.2216 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0628 | 0.5467 | 0.5467 |
Toxoplasma gondii | cathepsin CPL | 0.0628 | 0.5467 | 1 |
Leishmania major | cathepsin L-like protease | 0.0628 | 0.5467 | 1 |
Leishmania major | cathepsin L-like protease | 0.0628 | 0.5467 | 1 |
Onchocerca volvulus | 0.0628 | 0.5467 | 1 | |
Entamoeba histolytica | cysteine protease, putative | 0.0337 | 0.2216 | 0.4054 |
Onchocerca volvulus | Cathepsin L homolog | 0.0628 | 0.5467 | 1 |
Leishmania major | cathepsin L-like protease | 0.0628 | 0.5467 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0628 | 0.5467 | 0.5467 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0337 | 0.2216 | 0.2216 |
Loa Loa (eye worm) | ctsf protein | 0.0628 | 0.5467 | 0.5467 |
Onchocerca volvulus | 0.0628 | 0.5467 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0429 | 0.325 | 0.5946 |
Echinococcus granulosus | cysteine protease | 0.0337 | 0.2216 | 0.2216 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0429 | 0.325 | 0.325 |
Leishmania major | cathepsin L-like protease | 0.0628 | 0.5467 | 1 |
Plasmodium vivax | vivapain-3 | 0.0337 | 0.2216 | 0.4054 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0628 | 0.5467 | 0.5467 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0628 | 0.5467 | 0.5467 |
Brugia malayi | Cathepsin L-like precursor | 0.0429 | 0.325 | 0.325 |
Loa Loa (eye worm) | hypothetical protein | 0.1034 | 1 | 1 |
Trypanosoma cruzi | cysteine protease, putative | 0.0337 | 0.2216 | 0.2216 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0628 | 0.5467 | 0.5467 |
Plasmodium vivax | vivapain-2 | 0.0628 | 0.5467 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0337 | 0.2216 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Echinococcus granulosus | cathepsin L | 0.0337 | 0.2216 | 0.2216 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0198 | 0.067 | 0.067 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.1034 | 1 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0429 | 0.325 | 0.325 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0337 | 0.2216 | 0.4054 |
Loa Loa (eye worm) | cysteine protease | 0.0628 | 0.5467 | 0.5467 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0337 | 0.2216 | 0.4054 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0628 | 0.5467 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0198 | 0.067 | 0.067 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.1034 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.1034 | 1 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0337 | 0.2216 | 0.2216 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0628 | 0.5467 | 1 |
Echinococcus granulosus | cathepsin b | 0.1034 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0337 | 0.2216 | 0.4054 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0628 | 0.5467 | 0.5467 |
Entamoeba histolytica | cysteine protease, putative | 0.0337 | 0.2216 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0337 | 0.2216 | 0.2216 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0337 | 0.2216 | 0.4054 |
Echinococcus granulosus | cathepsin l1 | 0.0429 | 0.325 | 0.325 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0628 | 0.5467 | 0.5467 |
Giardia lamblia | Cathepsin B precursor | 0.0415 | 0.3093 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0628 | 0.5467 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0429 | 0.325 | 0.325 |
Loa Loa (eye worm) | hypothetical protein | 0.0628 | 0.5467 | 0.5467 |
Entamoeba histolytica | cysteine protease, putative | 0.0337 | 0.2216 | 0.4054 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0628 | 0.5467 | 0.5467 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Plasmodium vivax | unspecified product | 0.0198 | 0.067 | 0.1225 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0628 | 0.5467 | 1 |
Onchocerca volvulus | 0.0628 | 0.5467 | 1 | |
Brugia malayi | Cathepsin L-like precursor | 0.0628 | 0.5467 | 0.5467 |
Brugia malayi | Cathepsin L-like precursor | 0.0628 | 0.5467 | 0.5467 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0628 | 0.5467 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0628 | 0.5467 | 0.5467 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0337 | 0.2216 | 0.4054 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.1034 | 1 | 1 |
Plasmodium vivax | unspecified product | 0.0337 | 0.2216 | 0.4054 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0628 | 0.5467 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0198 | 0.067 | 0.067 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0628 | 0.5467 | 0.5467 |
Onchocerca volvulus | Cathepsin L homolog | 0.0628 | 0.5467 | 1 |
Entamoeba histolytica | cysteine proteinase 1, putative | 0.0337 | 0.2216 | 0.4054 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0198 | 0.067 | 0.067 |
Loa Loa (eye worm) | hypothetical protein | 0.0198 | 0.067 | 0.067 |
Entamoeba histolytica | cysteine protease, putative | 0.0337 | 0.2216 | 0.4054 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0415 | 0.3093 | 0.3093 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0337 | 0.2216 | 0.2216 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Onchocerca volvulus | 0.0429 | 0.325 | 0.5946 | |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0337 | 0.2216 | 0.2216 |
Leishmania major | cathepsin L-like protease | 0.0628 | 0.5467 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0337 | 0.2216 | 0.2216 |
Brugia malayi | Cathepsin L-like precursor | 0.0628 | 0.5467 | 0.5467 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0429 | 0.325 | 0.5946 |
Loa Loa (eye worm) | hypothetical protein | 0.0198 | 0.067 | 0.067 |
Loa Loa (eye worm) | hypothetical protein | 0.0429 | 0.325 | 0.325 |
Leishmania major | cysteine peptidase A (CPA) | 0.0628 | 0.5467 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.