Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0415 | 0.3093 | 0.5658 |
Leishmania major | cathepsin L-like protease | 0.0628 | 0.5467 | 1 |
Onchocerca volvulus | 0.0628 | 0.5467 | 1 | |
Entamoeba histolytica | cysteine proteinase, putative | 0.0628 | 0.5467 | 1 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0415 | 0.3093 | 0.2697 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0415 | 0.3093 | 0.3093 |
Entamoeba histolytica | cysteine protease, putative | 0.0628 | 0.5467 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0628 | 0.5467 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0628 | 0.5467 | 0.5467 |
Entamoeba histolytica | cysteine protease, putative | 0.0337 | 0.2216 | 0.4054 |
Leishmania major | cathepsin L-like protease | 0.0628 | 0.5467 | 1 |
Leishmania major | cathepsin L-like protease | 0.0628 | 0.5467 | 1 |
Onchocerca volvulus | 0.0628 | 0.5467 | 1 | |
Toxoplasma gondii | cathepsin CPL | 0.0628 | 0.5467 | 1 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0628 | 0.5467 | 0.5467 |
Echinococcus granulosus | cathepsin L cysteine protease | 0.0337 | 0.2216 | 0.2216 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0628 | 0.5467 | 0.5467 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0628 | 0.5467 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0628 | 0.5467 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0628 | 0.5467 | 0.5467 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0628 | 0.5467 | 0.5467 |
Giardia lamblia | Cathepsin B precursor | 0.0415 | 0.3093 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0628 | 0.5467 | 1 |
Brugia malayi | cathepsin L-like cysteine proteinase, identical | 0.0198 | 0.067 | 0.067 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0337 | 0.2216 | 0.4054 |
Entamoeba histolytica | cysteine protease, putative | 0.0337 | 0.2216 | 0.4054 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0628 | 0.5467 | 0.5467 |
Loa Loa (eye worm) | fibroinase | 0.0628 | 0.5467 | 0.5467 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0429 | 0.325 | 0.5946 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0628 | 0.5467 | 1 |
Onchocerca volvulus | 0.0628 | 0.5467 | 1 | |
Entamoeba histolytica | cysteine proteinase, putative | 0.0628 | 0.5467 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0628 | 0.5467 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0415 | 0.3093 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0337 | 0.2216 | 0.4054 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0198 | 0.067 | 0.067 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0429 | 0.325 | 0.325 |
Echinococcus multilocularis | cysteine protease | 0.0628 | 0.5467 | 0.5467 |
Brugia malayi | cathepsin F-like cysteine proteinase | 0.0198 | 0.067 | 0.067 |
Loa Loa (eye worm) | cathepsin B | 0.0415 | 0.3093 | 0.3093 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0628 | 0.5467 | 0.5467 |
Echinococcus multilocularis | cathepsin b | 0.1034 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0628 | 0.5467 | 0.5467 |
Echinococcus multilocularis | cathepsin b | 0.1034 | 1 | 1 |
Echinococcus multilocularis | cathepsin L | 0.0337 | 0.2216 | 0.2216 |
Leishmania major | cathepsin L-like protease | 0.0628 | 0.5467 | 1 |
Plasmodium vivax | vivapain-1 | 0.0337 | 0.2216 | 0.4054 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.1034 | 1 | 1 |
Echinococcus granulosus | cathepsin b | 0.1034 | 1 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 1 | 0.0337 | 0.2216 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Brugia malayi | cathepsin L-like precursor | 0.0429 | 0.325 | 0.325 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0337 | 0.2216 | 0.2216 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0337 | 0.2216 | 0.2216 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0337 | 0.2216 | 0.4054 |
Echinococcus granulosus | cathepsin l1 | 0.0628 | 0.5467 | 0.5467 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0628 | 0.5467 | 1 |
Onchocerca volvulus | 0.0628 | 0.5467 | 1 | |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0628 | 0.5467 | 0.5467 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0337 | 0.2216 | 0.4054 |
Brugia malayi | Cathepsin L-like precursor | 0.0429 | 0.325 | 0.325 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0337 | 0.2216 | 0.4054 |
Plasmodium vivax | vivapain-2 | 0.0628 | 0.5467 | 1 |
Onchocerca volvulus | 0.0628 | 0.5467 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Toxoplasma gondii | cathepsin B | 0.0415 | 0.3093 | 0.5658 |
Entamoeba histolytica | cysteine protease, putative | 0.0337 | 0.2216 | 0.4054 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0628 | 0.5467 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0337 | 0.2216 | 0.4054 |
Entamoeba histolytica | cysteine protease, putative | 0.0337 | 0.2216 | 0.4054 |
Leishmania major | cathepsin L-like protease | 0.0628 | 0.5467 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0628 | 0.5467 | 0.5467 |
Loa Loa (eye worm) | hypothetical protein | 0.0429 | 0.325 | 0.325 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Onchocerca volvulus | Cathepsin F homolog | 0.0628 | 0.5467 | 1 |
Entamoeba histolytica | cysteine proteinase 2 | 0.0337 | 0.2216 | 0.4054 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.0337 | 0.2216 | 0.2216 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0628 | 0.5467 | 0.5467 |
Schistosoma mansoni | cathepsin s | 0.0198 | 0.067 | 0.067 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0415 | 0.3093 | 0.3093 |
Entamoeba histolytica | cysteine protease, putative | 0.0337 | 0.2216 | 0.4054 |
Loa Loa (eye worm) | hypothetical protein | 0.0198 | 0.067 | 0.067 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0198 | 0.067 | 0.067 |
Entamoeba histolytica | cysteine proteinase 1, putative | 0.0337 | 0.2216 | 0.4054 |
Onchocerca volvulus | Cathepsin L homolog | 0.0628 | 0.5467 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0628 | 0.5467 | 0.5467 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0198 | 0.067 | 0.067 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0628 | 0.5467 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Leishmania major | cysteine peptidase A (CPA) | 0.0628 | 0.5467 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0429 | 0.325 | 0.325 |
Loa Loa (eye worm) | hypothetical protein | 0.0198 | 0.067 | 0.067 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0429 | 0.325 | 0.5946 |
Brugia malayi | Cathepsin L-like precursor | 0.0628 | 0.5467 | 0.5467 |
Leishmania major | cathepsin L-like protease | 0.0628 | 0.5467 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0337 | 0.2216 | 0.2216 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0337 | 0.2216 | 0.2216 |
Onchocerca volvulus | 0.0429 | 0.325 | 0.5946 | |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0337 | 0.2216 | 0.2216 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0628 | 0.5467 | 0.5467 |
Entamoeba histolytica | cysteine protease, putative | 0.0337 | 0.2216 | 0.4054 |
Loa Loa (eye worm) | hypothetical protein | 0.0429 | 0.325 | 0.325 |
Loa Loa (eye worm) | hypothetical protein | 0.0628 | 0.5467 | 0.5467 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0628 | 0.5467 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0415 | 0.3093 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0628 | 0.5467 | 0.5467 |
Echinococcus granulosus | cathepsin l1 | 0.0429 | 0.325 | 0.325 |
Entamoeba histolytica | cysteine protease, putative | 0.0337 | 0.2216 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0337 | 0.2216 | 0.2216 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0337 | 0.2216 | 0.4054 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0628 | 0.5467 | 0.5467 |
Plasmodium vivax | unspecified product | 0.0337 | 0.2216 | 0.4054 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.1034 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0337 | 0.2216 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0628 | 0.5467 | 0.5467 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0628 | 0.5467 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0628 | 0.5467 | 0.5467 |
Brugia malayi | Cathepsin L-like precursor | 0.0628 | 0.5467 | 0.5467 |
Onchocerca volvulus | 0.0628 | 0.5467 | 1 | |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0628 | 0.5467 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Plasmodium vivax | unspecified product | 0.0198 | 0.067 | 0.1225 |
Loa Loa (eye worm) | cysteine protease | 0.0628 | 0.5467 | 0.5467 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0337 | 0.2216 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0429 | 0.325 | 0.325 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0198 | 0.067 | 0.067 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.1034 | 1 | 1 |
Echinococcus granulosus | cathepsin L | 0.0337 | 0.2216 | 0.2216 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0337 | 0.2216 | 0.4054 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0337 | 0.2216 | 0.4054 |
Echinococcus granulosus | cathepsin b | 0.1034 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0628 | 0.5467 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0337 | 0.2216 | 0.2216 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.1034 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.1034 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0198 | 0.067 | 0.067 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0628 | 0.5467 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0337 | 0.2216 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0628 | 0.5467 | 0.5467 |
Plasmodium vivax | vivapain-3 | 0.0337 | 0.2216 | 0.4054 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0429 | 0.325 | 0.325 |
Leishmania major | cathepsin L-like protease | 0.0628 | 0.5467 | 1 |
Echinococcus granulosus | cysteine protease | 0.0337 | 0.2216 | 0.2216 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0429 | 0.325 | 0.5946 |
Onchocerca volvulus | 0.0628 | 0.5467 | 1 | |
Loa Loa (eye worm) | ctsf protein | 0.0628 | 0.5467 | 0.5467 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0337 | 0.2216 | 0.2216 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0628 | 0.5467 | 0.5467 |
Leishmania major | cathepsin L-like protease | 0.0628 | 0.5467 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0628 | 0.5467 | 1 |
Plasmodium vivax | vivapain-2 | 0.0628 | 0.5467 | 1 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0628 | 0.5467 | 0.5467 |
Trypanosoma cruzi | cysteine protease, putative | 0.0337 | 0.2216 | 0.2216 |
Loa Loa (eye worm) | hypothetical protein | 0.1034 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0429 | 0.325 | 0.325 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0628 | 0.5467 | 0.5467 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.