Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | endonuclease exonuclease phosphatase | 0.0441 | 0.5991 | 1 |
Echinococcus multilocularis | SAM and MBT domain containing protein | 0.0309 | 0.4105 | 0.6852 |
Echinococcus granulosus | SAM and MBT domain containing protein | 0.0309 | 0.4105 | 0.6852 |
Brugia malayi | mbt repeat family protein | 0.0366 | 0.491 | 1 |
Echinococcus multilocularis | polycomb protein SCMH1 | 0.0216 | 0.278 | 0.4641 |
Echinococcus granulosus | tumor suppressor p53 binding protein 1 | 0.0255 | 0.334 | 0.5574 |
Loa Loa (eye worm) | mbt repeat family protein | 0.0225 | 0.29 | 0.5908 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0216 | 0.278 | 0.278 |
Plasmodium vivax | JmjC domain containing protein | 0.0023 | 0.0023 | 0.5 |
Echinococcus granulosus | histone acetyltransferase MYST2 | 0.0085 | 0.0908 | 0.1515 |
Loa Loa (eye worm) | hypothetical protein | 0.0366 | 0.491 | 1 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0061 | 0.0562 | 0.0938 |
Echinococcus multilocularis | tumor suppressor p53 binding protein 1 | 0.0255 | 0.334 | 0.5574 |
Echinococcus granulosus | Jumonji AT rich interactive domain 1B | 0.0089 | 0.0969 | 0.1617 |
Toxoplasma gondii | PLU-1 family protein | 0.0034 | 0.0188 | 1 |
Echinococcus multilocularis | chromobox protein 2 | 0.0154 | 0.1892 | 0.3157 |
Schistosoma mansoni | phd finger protein | 0.0032 | 0.0153 | 0.0153 |
Echinococcus granulosus | endonuclease exonuclease phosphatase | 0.0441 | 0.5991 | 1 |
Echinococcus granulosus | suppression of tumorigenicity 18 protein | 0.0085 | 0.0908 | 0.1515 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0073 | 0.0734 | 0.1226 |
Echinococcus multilocularis | Jumonji, AT rich interactive domain 1B | 0.0089 | 0.0969 | 0.1617 |
Onchocerca volvulus | Polycomb protein Sfmbt homolog | 0.0366 | 0.491 | 1 |
Echinococcus granulosus | histone acetyltransferase myst3 | 0.0032 | 0.0153 | 0.0255 |
Brugia malayi | jmjC domain containing protein | 0.0107 | 0.1223 | 0.2491 |
Plasmodium falciparum | JmjC domain-containing protein, putative | 0.0023 | 0.0023 | 0.5 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0107 | 0.1223 | 0.2491 |
Loa Loa (eye worm) | hypothetical protein | 0.0085 | 0.0908 | 0.1849 |
Echinococcus granulosus | chromobox protein 2 | 0.0154 | 0.1892 | 0.3157 |
Echinococcus multilocularis | histone acetyltransferase myst3 | 0.0032 | 0.0153 | 0.0255 |
Brugia malayi | C2-HC type zinc finger protein C.e-MyT1 | 0.0085 | 0.0908 | 0.1849 |
Echinococcus multilocularis | suppression of tumorigenicity 18 protein | 0.0085 | 0.0908 | 0.1515 |
Schistosoma mansoni | hypothetical protein | 0.0255 | 0.334 | 0.334 |
Schistosoma mansoni | chromobox protein | 0.0154 | 0.1892 | 0.1892 |
Schistosoma mansoni | myelin transcription factor 1 myt1 | 0.0085 | 0.0908 | 0.0908 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0216 | 0.278 | 0.278 |
Schistosoma mansoni | scm-relatedprotein containing 4 mbt domains (sfmbt) | 0.0309 | 0.4105 | 0.4105 |
Loa Loa (eye worm) | MBCTL1 | 0.0085 | 0.0908 | 0.1849 |
Echinococcus multilocularis | histone acetyltransferase MYST2 | 0.0085 | 0.0908 | 0.1515 |
Echinococcus granulosus | polycomb protein SCMH1 | 0.0216 | 0.278 | 0.4641 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0073 | 0.0734 | 0.0734 |
Brugia malayi | mbt repeat family protein | 0.0225 | 0.29 | 0.5908 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0073 | 0.0734 | 0.0734 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.