Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | sodium channel, voltage-gated, type IX, alpha subunit | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | AGC family protein kinase | 0.0029 | 0.0295 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0029 | 0.0295 | 0.0295 |
Echinococcus multilocularis | microtubule associated serine:threonine protein | 0.0121 | 0.1468 | 0.1468 |
Trichomonas vaginalis | AGC family protein kinase | 0.0029 | 0.0295 | 1 |
Echinococcus granulosus | Microtubule-associated serine/threonine-protein kinase | 0.0121 | 0.1468 | 0.1468 |
Loa Loa (eye worm) | AGC/MAST/MAST protein kinase | 0.0121 | 0.1468 | 0.1468 |
Trichomonas vaginalis | AGC family protein kinase | 0.0029 | 0.0295 | 1 |
Brugia malayi | microtubule-associated serine/threonine protein kinase 2 (MAST2) | 0.0093 | 0.1106 | 0.1106 |
Echinococcus multilocularis | serine:threonine protein kinase greatwall | 0.0029 | 0.0295 | 0.0295 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0092 | 0.11 | 0.11 |
Trichomonas vaginalis | AGC family protein kinase | 0.0029 | 0.0295 | 1 |
Brugia malayi | KIAA0303 | 0.0029 | 0.0295 | 0.0295 |
Onchocerca volvulus | 0.0252 | 0.3118 | 0.5 | |
Trichomonas vaginalis | AGC family protein kinase | 0.0029 | 0.0295 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0029 | 0.0295 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0029 | 0.0295 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.0029 | 0.0295 | 0.5 |
Echinococcus granulosus | voltage gated sodium channel Nav1 alpha subunit | 0.0045 | 0.0506 | 0.0506 |
Entamoeba histolytica | hypothetical protein | 0.0029 | 0.0295 | 0.5 |
Trichomonas vaginalis | AGC family protein kinase | 0.0029 | 0.0295 | 1 |
Echinococcus multilocularis | sodium channel protein | 0.0045 | 0.0506 | 0.0506 |
Trichomonas vaginalis | AGC family protein kinase | 0.0029 | 0.0295 | 1 |
Leishmania major | calcium channel protein, putative,ion transporter, putative | 0.0045 | 0.0506 | 0.5 |
Trichomonas vaginalis | AGC family protein kinase | 0.0029 | 0.0295 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0029 | 0.0295 | 1 |
Echinococcus granulosus | sodium channel protein | 0.0045 | 0.0506 | 0.0506 |
Trichomonas vaginalis | AGC family protein kinase | 0.0029 | 0.0295 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0029 | 0.0295 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | = 5.4089 | Inhibition of NaV1.7 ion channel (unknown origin) | ChEMBL. | 23177785 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.