Detailed information for compound 1730898

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 1408.81 | Formula: C75H117N13O13
  • H donors: 13 H acceptors: 13 LogP: 8.35 Rotable bonds: 39
    Rule of 5 violations (Lipinski): 4
  • SMILES: CC(C[C@H](NC(=O)[C@H]1CCC[C@@H]1NC(=O)[C@H]1CCC[C@@H]1NC(=O)C)CC(=O)N[C@H]1CCC[C@@H]1C(=O)N[C@H]1CCC[C@@H]1C(=O)N[C@H]1CCC[C@@H]1C(=O)N[C@H]1CCC[C@@H]1C(=O)N[C@H]1CCC[C@@H]1C(=O)N[C@H]1CCC[C@@H]1C(=O)N[C@H]1CCC[C@@H]1C(=O)N[C@H]1CCC[C@@H]1C(=O)N[C@H]1CCC[C@@H]1C(=O)N)C
  • InChi: 1S/C75H117N13O13/c1-39(2)37-41(78-66(92)45-18-7-29-56(45)81-67(93)43-16-5-27-54(43)77-40(3)89)38-64(90)79-55-28-6-17-44(55)68(94)82-58-31-9-20-47(58)70(96)84-60-33-11-22-49(60)72(98)86-62-35-13-24-51(62)74(100)88-63-36-14-25-52(63)75(101)87-61-34-12-23-50(61)73(99)85-59-32-10-21-48(59)71(97)83-57-30-8-19-46(57)69(95)80-53-26-4-15-42(53)65(76)91/h39,41-63H,4-38H2,1-3H3,(H2,76,91)(H,77,89)(H,78,92)(H,79,90)(H,80,95)(H,81,93)(H,82,94)(H,83,97)(H,84,96)(H,85,99)(H,86,98)(H,87,101)(H,88,100)/t41-,42-,43-,44-,45-,46-,47-,48-,49-,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,60-,61-,62-,63-/m0/s1
  • InChiKey: CUMZEEVBNLSGNJ-RWVDNASCSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus cyclins 0.0157 0.0123 0.0044
Loa Loa (eye worm) SH2 domain-containing protein 0.1395 0.4154 0.4198
Entamoeba histolytica protein kinase domain containing protein 0.1005 0.2886 0.3782
Trichomonas vaginalis STE family protein kinase 0.1005 0.2886 1
Echinococcus multilocularis gamma secretase subunit aph 1 0.0296 0.0575 0.0499
Loa Loa (eye worm) TK/ALK protein kinase 0.1005 0.2886 0.2891
Trichomonas vaginalis TKL family protein kinase 0.1005 0.2886 1
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.101 0.2902 1
Brugia malayi SH2 domain containing protein 0.1395 0.4154 0.5545
Schistosoma mansoni serine/threonine protein kinase 0.1005 0.2886 0.3818
Schistosoma mansoni protein kinase 0.1005 0.2886 0.3818
Echinococcus multilocularis tyrosine protein kinase csk 0.1005 0.2886 0.2828
Brugia malayi Protein kinase domain containing protein 0.24 0.7428 1
Brugia malayi RhoGAP domain containing protein 0.1395 0.4154 0.5545
Echinococcus granulosus tensin C1 domain containing phosphatase 0.1395 0.4154 0.4107
Schistosoma mansoni tyrosine kinase 0.1005 0.2886 0.3818
Brugia malayi protein-tyrosine kinase 0.24 0.7428 1
Trichomonas vaginalis TKL family protein kinase 0.1005 0.2886 1
Brugia malayi Cyclin, N-terminal domain containing protein 0.0157 0.0123 0.0059
Schistosoma mansoni tyrosine protein kinase 0.1005 0.2886 0.3818
Schistosoma mansoni tyrosine kinase 0.1005 0.2886 0.3818
Brugia malayi Protein kinase domain containing protein 0.1005 0.2886 0.3818
Trichomonas vaginalis TKL family protein kinase 0.1005 0.2886 1
Loa Loa (eye worm) TK/INSR protein kinase 0.1005 0.2886 0.2891
Entamoeba histolytica protein kinase domain containing protein 0.1005 0.2886 0.3782
Echinococcus multilocularis cyclins 0.0157 0.0123 0.0044
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.1005 0.2886 0.9943
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.1395 0.4154 0.4107
Brugia malayi Furin-like cysteine rich region family protein 0.1005 0.2886 0.3818
Echinococcus multilocularis tyrosine protein kinase HCK 0.1005 0.2886 0.2828
Loa Loa (eye worm) hypothetical protein 0.1005 0.2886 0.2891
Echinococcus granulosus tyrosine protein kinase HCK 0.1005 0.2886 0.2828
Echinococcus granulosus tyrosine kinase 0.24 0.7428 0.7407
Trypanosoma cruzi protein kinase, putative 0.1005 0.2886 0.994
Echinococcus multilocularis tyrosine protein kinase csk 0.1005 0.2886 0.2828
Echinococcus multilocularis SH2 motif 0.1395 0.4154 0.4107
Onchocerca volvulus 0.1395 0.4154 0.5518
Schistosoma mansoni protein kinase 0.0839 0.2343 0.3079
Loa Loa (eye worm) TK protein kinase 0.1005 0.2886 0.2891
Entamoeba histolytica protein kinase domain containing protein 0.1005 0.2886 0.3782
Schistosoma mansoni hypothetical protein 0.025 0.0426 0.047
Loa Loa (eye worm) TK/CSK protein kinase 0.1005 0.2886 0.2891
Entamoeba histolytica tyrosine kinase, putative 0.1005 0.2886 0.3782
Echinococcus multilocularis fibroblast growth factor receptor 4 0.1005 0.2886 0.2828
Brugia malayi Protein kinase domain containing protein 0.1005 0.2886 0.3818
Schistosoma mansoni tensin 0.1395 0.4154 0.5545
Brugia malayi Variant SH3 domain containing protein 0.1395 0.4154 0.5545
Trypanosoma brucei Flagellum attachment zone protein 20 0.1005 0.2886 0.994
Schistosoma mansoni tyrosine kinase 0.1005 0.2886 0.3818
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.101 0.2902 1
Entamoeba histolytica hypothetical protein 0.1005 0.2886 0.3782
Trichomonas vaginalis TKL family protein kinase 0.1005 0.2886 1
Entamoeba histolytica protein kinase, putative 0.1005 0.2886 0.3782
Loa Loa (eye worm) hypothetical protein 0.1395 0.4154 0.4198
Schistosoma mansoni serine/threonine protein kinase 0.0183 0.0209 0.0175
Brugia malayi C-terminal src kinase protein 1 0.1005 0.2886 0.3818
Trichomonas vaginalis conserved hypothetical protein 0.1005 0.2886 1
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.101 0.2902 1
Entamoeba histolytica serine/threonine kinase, putative 0.1005 0.2886 0.3782
Loa Loa (eye worm) variant SH3 domain-containing protein 0.1395 0.4154 0.4198
Trichomonas vaginalis TKL family protein kinase 0.1005 0.2886 1
Brugia malayi Protein kinase domain containing protein 0.1005 0.2886 0.3818
Entamoeba histolytica SH2 domain containing protein 0.1395 0.4154 0.5518
Echinococcus multilocularis tyrosine kinase 0.1005 0.2886 0.2828
Entamoeba histolytica protein kinase, putative 0.1005 0.2886 0.3782
Echinococcus multilocularis cyclins 0.0157 0.0123 0.0044
Entamoeba histolytica receptor protein kinase, putative 0.1005 0.2886 0.3782
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.1005 0.2886 0.3782
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.1005 0.2886 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.1005 0.2886 0.3782
Echinococcus multilocularis SH2 domain containing protein 7 0.1395 0.4154 0.4107
Trichomonas vaginalis TKL family protein kinase 0.1005 0.2886 1
Echinococcus granulosus tyrosine protein kinase Fyn 0.24 0.7428 0.7407
Brugia malayi Guanylyl cyclase protein 23 0.1005 0.2886 0.3818
Schistosoma mansoni GTPase activating protein 0.1395 0.4154 0.5545
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.1395 0.4154 0.4107
Onchocerca volvulus 0.1395 0.4154 0.5518
Loa Loa (eye worm) hypothetical protein 0.1005 0.2886 0.2891
Trichomonas vaginalis TKL family protein kinase 0.1005 0.2886 1
Echinococcus granulosus suppressor of cytokine signaling 7 0.1395 0.4154 0.4107
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.1005 0.2886 0.994
Brugia malayi bone morphogenetic protein type 1 receptor 0.1005 0.2886 0.3818
Echinococcus granulosus natriuretic peptide receptor 1 0.1005 0.2886 0.2828
Schistosoma mansoni growth factor receptor-bound protein 0.1395 0.4154 0.5545
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.1005 0.2886 0.2828
Schistosoma mansoni cyclin B 0.0157 0.0123 0.0059
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.24 0.7428 0.7407
Entamoeba histolytica tyrosine kinase, putative 0.1005 0.2886 0.3782
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0734 0.2001 0.2615
Schistosoma mansoni src-type protein tyrosine kinase-related 0.1005 0.2886 0.3818
Echinococcus multilocularis receptor type guanylyl cyclase 0.1005 0.2886 0.2828
Echinococcus granulosus tyrosine kinase 0.1005 0.2886 0.2828
Echinococcus multilocularis SH2 domain containing adapter protein F 0.1395 0.4154 0.4107
Echinococcus granulosus activated cdc42 kinase 1 0.1005 0.2886 0.2828
Trichomonas vaginalis TKL family protein kinase 0.1005 0.2886 1
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.1395 0.4154 0.4198
Brugia malayi Protein kinase domain containing protein 0.1005 0.2886 0.3818
Entamoeba histolytica protein kinase domain containing protein 0.1005 0.2886 0.3782
Loa Loa (eye worm) TK/FER protein kinase 0.1005 0.2886 0.2891
Brugia malayi Protein kinase domain containing protein 0.1005 0.2886 0.3818
Onchocerca volvulus 0.24 0.7428 1
Trypanosoma brucei protein kinase, putative 0.101 0.2902 1
Echinococcus granulosus tyrosine protein kinase Lyn 0.2405 0.7445 0.7424
Echinococcus granulosus tyrosine protein kinase Srms 0.24 0.7428 0.7407
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.1005 0.2886 0.3782
Giardia lamblia Kinase 0.1005 0.2886 1
Echinococcus multilocularis cyclin b3 0.0157 0.0123 0.0044
Trichomonas vaginalis conserved hypothetical protein 0.1005 0.2886 1
Trichomonas vaginalis TKL family protein kinase 0.1005 0.2886 1
Trichomonas vaginalis TKL family protein kinase 0.1005 0.2886 1
Echinococcus granulosus tyrosine protein kinase Fyn 0.24 0.7428 0.7407
Echinococcus granulosus tyrosine protein kinase Fyn 0.24 0.7428 0.7407
Entamoeba histolytica hypothetical protein 0.1005 0.2886 0.3782
Schistosoma mansoni nck2/grb4 0.1395 0.4154 0.5545
Entamoeba histolytica protein kinase, putative 0.1005 0.2886 0.3782
Loa Loa (eye worm) TK/KIN6 protein kinase 0.1005 0.2886 0.2891
Loa Loa (eye worm) TK/KIN16 protein kinase 0.1005 0.2886 0.2891
Trichomonas vaginalis conserved hypothetical protein 0.1005 0.2886 1
Loa Loa (eye worm) TK/FER protein kinase 0.1005 0.2886 0.2891
Entamoeba histolytica hypothetical protein 0.1005 0.2886 0.3782
Schistosoma mansoni tyrosine kinase 0.1005 0.2886 0.3818
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.1005 0.2886 0.3782
Schistosoma mansoni tyrosine kinase 0.1005 0.2886 0.3818
Leishmania major hypothetical protein, conserved 0.1005 0.2886 0.994
Brugia malayi Protein kinase domain containing protein 0.1005 0.2886 0.3818
Schistosoma mansoni tyrosine kinase 0.1005 0.2886 0.3818
Loa Loa (eye worm) SH2 domain-containing protein 0.1395 0.4154 0.4198
Schistosoma mansoni protein kinase 0.1005 0.2886 0.3818
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.1005 0.2886 0.2828
Echinococcus granulosus retinal guanylyl cyclase 2 0.1005 0.2886 0.2828
Echinococcus multilocularis ephrin type A receptor 4 A 0.1005 0.2886 0.2828
Schistosoma mansoni tyrosine kinase 0.1005 0.2886 0.3818
Loa Loa (eye worm) AGC/PKA protein kinase 0.0183 0.0209 0.0132
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.1395 0.4154 0.5545
Echinococcus granulosus dual specificity testis-specific protein kinase 0.101 0.2902 0.2845
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.1005 0.2886 0.3782
Schistosoma mansoni tyrosine kinase 0.1005 0.2886 0.3818
Echinococcus multilocularis tyrosine protein kinase pr2 0.1005 0.2886 0.2828
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.1005 0.2886 0.3818
Brugia malayi Tyrosine-protein kinase abl-1 0.24 0.7428 1
Onchocerca volvulus 0.24 0.7428 1
Echinococcus multilocularis cyclins 0.0157 0.0123 0.0044
Entamoeba histolytica protein kinase, putative 0.1005 0.2886 0.3782
Brugia malayi hypothetical protein 0.1005 0.2886 0.3818
Echinococcus granulosus cyclins 0.0157 0.0123 0.0044
Brugia malayi Protein kinase domain containing protein 0.1005 0.2886 0.3818
Echinococcus multilocularis 0.1395 0.4154 0.4107
Entamoeba histolytica tyrosine kinase, putative 0.1005 0.2886 0.3782
Entamoeba histolytica protein kinase domain containing protein 0.1005 0.2886 0.3782
Entamoeba histolytica PH domain containing protein kinase, putative 0.0183 0.0209 0.0117
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.1395 0.4154 0.5518
Trichomonas vaginalis conserved hypothetical protein 0.1005 0.2886 1
Brugia malayi Protein kinase domain containing protein 0.1005 0.2886 0.3818
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.1005 0.2886 0.2891
Trichomonas vaginalis conserved hypothetical protein 0.1005 0.2886 1
Loa Loa (eye worm) hypothetical protein 0.1395 0.4154 0.4198
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.1005 0.2886 0.3782
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.1005 0.2886 0.3818
Loa Loa (eye worm) hypothetical protein 0.1005 0.2886 0.2891
Entamoeba histolytica tyrosine kinase, putative 0.1005 0.2886 0.3782
Echinococcus multilocularis tyrosine protein kinase Fyn 0.24 0.7428 0.7407
Loa Loa (eye worm) hypothetical protein 0.0357 0.0775 0.0716
Loa Loa (eye worm) protein kinase domain-containing protein 0.1005 0.2886 0.2891
Brugia malayi gamma-secretase subunit aph-1 0.0296 0.0575 0.0674
Loa Loa (eye worm) hypothetical protein 0.025 0.0426 0.0356
Entamoeba histolytica receptor protein kinase, putative 0.1005 0.2886 0.3782
Schistosoma mansoni suppressor of cytokine signaling 0.1395 0.4154 0.5545
Schistosoma mansoni protein kinase 0.101 0.2902 0.3841
Schistosoma mansoni tyrosine kinase 0.24 0.7428 1
Trypanosoma brucei Pseudokinase, putative 0.1005 0.2886 0.994
Trichomonas vaginalis TK family protein kinase 0.1005 0.2886 1
Loa Loa (eye worm) gamma-secretase subunit aph-1 0.0296 0.0575 0.051
Echinococcus granulosus gamma secretase subunit aph 1 0.0296 0.0575 0.0499
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.1005 0.2886 0.3818
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.1005 0.2886 0.3782
Loa Loa (eye worm) TK/FER protein kinase 0.24 0.7428 0.7571
Leishmania major protein kinase A catalytic subunit 0.0183 0.0209 0.0307
Brugia malayi SH2 domain containing protein 0.1395 0.4154 0.5545
Plasmodium vivax tyrosine kinase-like protein, putative 0.1005 0.2886 1
Schistosoma mansoni tyrosine kinase 0.1005 0.2886 0.3818
Toxoplasma gondii AGC kinase 0.0183 0.0209 0.0719
Loa Loa (eye worm) hypothetical protein 0.1395 0.4154 0.4198
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0183 0.0209 0.0307
Loa Loa (eye worm) hypothetical protein 0.1395 0.4154 0.4198
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.1395 0.4154 0.5545
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.1005 0.2886 0.3782
Trichomonas vaginalis TKL family protein kinase 0.1005 0.2886 1
Brugia malayi Probable tyrosine-protein kinase kin-31 0.1005 0.2886 0.3818
Entamoeba histolytica SH2-protein kinase domain containing protein 0.24 0.7428 1
Echinococcus multilocularis apoptotic protease activating factor 1 0.025 0.0426 0.0348
Echinococcus multilocularis c src tyrosine kinase 0.24 0.7428 0.7407
Onchocerca volvulus 0.1395 0.4154 0.5518
Loa Loa (eye worm) TK/FAK protein kinase 0.1005 0.2886 0.2891
Entamoeba histolytica tyrosine kinase, putative 0.1005 0.2886 0.3782
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0183 0.0209 0.0307
Loa Loa (eye worm) hypothetical protein 0.1395 0.4154 0.4198
Echinococcus multilocularis tyrosine protein kinase ABL1 0.24 0.7428 0.7407
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.1005 0.2886 0.2828
Entamoeba histolytica tyrosine kinase, putative 0.1005 0.2886 0.3782
Schistosoma mansoni tyrosine kinase 0.1005 0.2886 0.3818
Loa Loa (eye worm) SH2 domain-containing protein 0.1395 0.4154 0.4198
Entamoeba histolytica protein kinase domain containing protein 0.1005 0.2886 0.3782
Trichomonas vaginalis TKL family protein kinase 0.1005 0.2886 1
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0183 0.0209 0.0307
Loa Loa (eye worm) TK/FER protein kinase 0.24 0.7428 0.7571
Trichomonas vaginalis TKL family protein kinase 0.1005 0.2886 1
Brugia malayi Protein kinase domain containing protein 0.1005 0.2886 0.3818
Brugia malayi STAT protein, DNA binding domain containing protein 0.1395 0.4154 0.5545
Leishmania major protein kinase A catalytic subunit isoform 2 0.0183 0.0209 0.0307
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.1005 0.2886 0.2828
Entamoeba histolytica protein kinase, putative 0.14 0.4171 0.5541
Entamoeba histolytica protein kinase, putative 0.1005 0.2886 0.3782
Schistosoma mansoni tensin-related 0.1395 0.4154 0.5545
Schistosoma mansoni protein kinase 0.1005 0.2886 0.3818
Entamoeba histolytica tyrosine kinase, putative 0.1005 0.2886 0.3782
Echinococcus granulosus integrin linked protein kinase 0.1005 0.2886 0.2828
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.1005 0.2886 0.2828
Echinococcus multilocularis tyrosine protein kinase Fyn 0.24 0.7428 0.7407
Echinococcus granulosus raf serine:threonine protein kinase 0.1005 0.2886 0.2828
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.1005 0.2886 1
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0183 0.0209 0.0307
Trichomonas vaginalis conserved hypothetical protein 0.1005 0.2886 1
Loa Loa (eye worm) TK/RYK protein kinase 0.1005 0.2886 0.2891
Entamoeba histolytica protein kinase, putative 0.1005 0.2886 0.3782
Echinococcus granulosus epidermal growth factor receptor 0.1005 0.2886 0.2828
Brugia malayi Protein kinase domain containing protein 0.1005 0.2886 0.3818
Echinococcus granulosus N chimaerin 0.1395 0.4154 0.4107
Loa Loa (eye worm) TK/EPH protein kinase 0.1005 0.2886 0.2891
Echinococcus multilocularis tyrosine protein kinase Src64B 0.24 0.7428 0.7407
Echinococcus granulosus insulin growth factor 1 receptor beta 0.1005 0.2886 0.2828
Onchocerca volvulus 0.24 0.7428 1
Brugia malayi Variant SH3 domain containing protein 0.1395 0.4154 0.5545
Entamoeba histolytica serine/threonine kinase, putative 0.1005 0.2886 0.3782
Echinococcus granulosus protein tyrosine kinase 0.1005 0.2886 0.2828
Echinococcus multilocularis cyclins 0.0157 0.0123 0.0044
Brugia malayi Protein-tyrosine phosphatase containing protein 0.1395 0.4154 0.5545
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.1005 0.2886 0.2828
Trichomonas vaginalis TKL family protein kinase 0.1005 0.2886 1
Entamoeba histolytica protein kinase, putative 0.1005 0.2886 0.3782
Trichomonas vaginalis TKL family protein kinase 0.1005 0.2886 1
Trichomonas vaginalis TKL family protein kinase 0.1005 0.2886 1
Echinococcus multilocularis tyrosine protein kinase csk 0.1005 0.2886 0.2828
Schistosoma mansoni serine/threonine protein kinase 0.0183 0.0209 0.0175
Echinococcus multilocularis tyrosine protein kinase 0.1005 0.2886 0.2828
Entamoeba histolytica tyrosine kinase, putative 0.1005 0.2886 0.3782
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.1005 0.2886 0.3818
Brugia malayi Tyrosine-protein kinase PR2 0.1005 0.2886 0.3818
Brugia malayi Protein kinase domain containing protein 0.1005 0.2886 0.3818
Echinococcus multilocularis FL cytokine receptor 0.1005 0.2886 0.2828
Loa Loa (eye worm) serine/threonine protein kinase 0.1005 0.2886 0.2891
Loa Loa (eye worm) hypothetical protein 0.1005 0.2886 0.2891
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.1395 0.4154 0.5545
Toxoplasma gondii AGC kinase 0.0183 0.0209 0.0719
Loa Loa (eye worm) TK/ABL protein kinase 0.24 0.7428 0.7571
Entamoeba histolytica tyrosin kinase, putative 0.1005 0.2886 0.3782
Schistosoma mansoni tyrosine kinase 0.1005 0.2886 0.3818
Loa Loa (eye worm) TK/FER protein kinase 0.24 0.7428 0.7571
Echinococcus multilocularis protein tyrosine kinase 0.1005 0.2886 0.2828
Entamoeba histolytica cysteine surface protein, putative 0.1005 0.2886 0.3782
Trichomonas vaginalis TKL family protein kinase 0.1005 0.2886 1
Entamoeba histolytica PH domain containing protein kinase, putative 0.0183 0.0209 0.0117
Entamoeba histolytica protein kinase, putative 0.1005 0.2886 0.3782
Echinococcus multilocularis protein kinase 0.1005 0.2886 0.2828
Trichomonas vaginalis TKL family protein kinase 0.1005 0.2886 1
Echinococcus multilocularis signal transduction protein lnk realted 0.1395 0.4154 0.4107
Echinococcus multilocularis cyclin B 0.0157 0.0123 0.0044
Echinococcus multilocularis tensin 0.1395 0.4154 0.4107
Onchocerca volvulus 0.1005 0.2886 0.3782
Trichomonas vaginalis protein tyrosine kinase, putative 0.1005 0.2886 1
Echinococcus granulosus retinal guanylyl cyclase 2 0.1005 0.2886 0.2828
Echinococcus multilocularis dual specificity testis specific protein kinase 0.101 0.2902 0.2845
Entamoeba histolytica protein kinase domain containing protein 0.1005 0.2886 0.3782
Echinococcus granulosus tensin 0.1395 0.4154 0.4107
Entamoeba histolytica protein kinase, putative 0.1005 0.2886 0.3782
Toxoplasma gondii STE kinase 0.1005 0.2886 0.9943
Entamoeba histolytica protein kinase domain containing protein 0.1005 0.2886 0.3782
Echinococcus granulosus SH2 domain containing adapter protein F 0.1395 0.4154 0.4107
Plasmodium falciparum protein kinase, putative 0.101 0.2902 1
Echinococcus granulosus tyrosine protein kinase csk 0.1005 0.2886 0.2828
Loa Loa (eye worm) cyclin domain-containing protein 0.0551 0.1405 0.1365
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.1005 0.2886 0.3782
Entamoeba histolytica protein kinase domain containing protein 0.1005 0.2886 0.3782
Brugia malayi hypothetical protein 0.24 0.7428 1
Trichomonas vaginalis TKL family protein kinase 0.1005 0.2886 1
Entamoeba histolytica protein kinase domain containing protein 0.1005 0.2886 0.3782
Entamoeba histolytica tyrosine kinase, putative 0.1005 0.2886 0.3782
Leishmania major protein kinase, putative 0.101 0.2902 1
Schistosoma mansoni ephrin receptor 0.1005 0.2886 0.3818
Echinococcus multilocularis epidermal growth factor receptor 0.1005 0.2886 0.2828
Trichomonas vaginalis TKL family protein kinase 0.1005 0.2886 1
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.1395 0.4154 0.5518
Onchocerca volvulus 0.1395 0.4154 0.5518
Loa Loa (eye worm) TK/FER protein kinase 0.1005 0.2886 0.2891
Entamoeba histolytica protein kinase domain containing protein 0.1005 0.2886 0.3782
Echinococcus granulosus suppressor of cytokine signaling 6 0.1395 0.4154 0.4107
Trichomonas vaginalis conserved hypothetical protein 0.1005 0.2886 1
Loa Loa (eye worm) hypothetical protein 0.1005 0.2886 0.2891
Entamoeba histolytica tyrosine kinase, putative 0.1005 0.2886 0.3782
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.1005 0.2886 0.2891
Entamoeba histolytica protein kinase domain containing protein 0.1005 0.2886 0.3782
Schistosoma mansoni tyrosine kinase 0.1005 0.2886 0.3818
Echinococcus multilocularis tyrosine kinase 0.24 0.7428 0.7407
Echinococcus multilocularis G2:mitotic specific cyclin B3 0.0157 0.0123 0.0044
Brugia malayi cytokine inducible SH2-containing protein 5 0.1395 0.4154 0.5545
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0183 0.0209 0.0719
Brugia malayi SH2 domain containing protein 0.1395 0.4154 0.5545
Schistosoma mansoni hypothetical protein 0.1005 0.2886 0.3818
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0183 0.0209 0.0307
Brugia malayi Sex muscle abnormal protein 5 0.1395 0.4154 0.5545
Entamoeba histolytica protein kinase domain containing protein 0.1005 0.2886 0.3782
Entamoeba histolytica tyrosin kinase, putative 0.1005 0.2886 0.3782
Trichomonas vaginalis TKL family protein kinase 0.1005 0.2886 1
Brugia malayi Variant SH3 domain containing protein 0.1395 0.4154 0.5545
Schistosoma mansoni serine/threonine protein kinase 0.1005 0.2886 0.3818
Entamoeba histolytica protein kinase, putative 0.1005 0.2886 0.3782
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0183 0.0209 0.0129
Brugia malayi SH2 domain containing protein 0.24 0.7428 1
Schistosoma mansoni hypothetical protein 0.1395 0.4154 0.5545
Onchocerca volvulus 0.1395 0.4154 0.5518
Schistosoma mansoni tyrosine kinase 0.1005 0.2886 0.3818
Echinococcus granulosus cyclins 0.0157 0.0123 0.0044
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.1005 0.2886 0.2891
Loa Loa (eye worm) TK/FER protein kinase 0.1005 0.2886 0.2891
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0183 0.0209 0.0307
Entamoeba histolytica tyrosine kinase, putative 0.1005 0.2886 0.3782
Echinococcus granulosus tyrosine protein kinase Src42A 0.1395 0.4154 0.4107
Echinococcus granulosus epidermal growth factor receptor 0.1005 0.2886 0.2828
Schistosoma mansoni serine/threonine protein kinase 0.1005 0.2886 0.3818
Loa Loa (eye worm) AGC/PKA protein kinase 0.0183 0.0209 0.0132
Schistosoma mansoni tensin-related 0.1395 0.4154 0.5545
Echinococcus granulosus receptor type guanylyl cyclase 0.1005 0.2886 0.2828
Loa Loa (eye worm) TK/FER protein kinase 0.1005 0.2886 0.2891
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.1005 0.2886 0.2828
Onchocerca volvulus Cell death protein 3 homolog 0.0357 0.0775 0.0893
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.1005 0.2886 0.2828
Loa Loa (eye worm) TK protein kinase 0.1005 0.2886 0.2891
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.1005 0.2886 0.2828
Loa Loa (eye worm) TK/Met protein kinase 0.1005 0.2886 0.2891
Schistosoma mansoni cyclin B3 0.0157 0.0123 0.0059
Entamoeba histolytica serine/threonine kinase, putative 0.1005 0.2886 0.3782
Trichomonas vaginalis TKL family protein kinase 0.1005 0.2886 1
Schistosoma mansoni tyrosine kinase 0.24 0.7428 1
Loa Loa (eye worm) RGC/RGC protein kinase 0.1005 0.2886 0.2891
Echinococcus granulosus insulin receptor 0.1005 0.2886 0.2828
Loa Loa (eye worm) TK/FER protein kinase 0.1005 0.2886 0.2891
Echinococcus multilocularis retinal guanylyl cyclase 2 0.1005 0.2886 0.2828
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0183 0.0209 0.0129
Trichomonas vaginalis protein kinase atn1, putative 0.1005 0.2886 1
Trichomonas vaginalis TKL family protein kinase 0.1005 0.2886 1
Trichomonas vaginalis TKL family protein kinase 0.1005 0.2886 1
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.1395 0.4154 0.5545
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.1005 0.2886 0.2828
Trichomonas vaginalis TKL family protein kinase 0.1005 0.2886 1
Echinococcus granulosus expressed conserved protein 0.1395 0.4154 0.4107
Trichomonas vaginalis TKL family protein kinase 0.1005 0.2886 1
Loa Loa (eye worm) protein-tyrosine phosphatase 0.1395 0.4154 0.4198
Schistosoma mansoni vav2 0.1395 0.4154 0.5545
Entamoeba histolytica ankyrin repeat protein 0.1005 0.2886 0.3782
Schistosoma mansoni tyrosine kinase 0.24 0.7428 1
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0183 0.0209 0.0307
Brugia malayi Cell death protein 3 precursor 0.0357 0.0775 0.0946
Brugia malayi Protein kinase domain containing protein 0.24 0.7428 1
Loa Loa (eye worm) STAT protein 0.1395 0.4154 0.4198
Echinococcus multilocularis kinase suppressor of Ras 1 0.1005 0.2886 0.2828
Echinococcus granulosus tyrosine protein kinase ABL1 0.24 0.7428 0.7407
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.24 0.7428 0.7407
Onchocerca volvulus 0.1005 0.2886 0.3782
Schistosoma mansoni protein kinase 0.1005 0.2886 0.3818
Echinococcus granulosus tyrosine protein kinase csk 0.1005 0.2886 0.2828
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.1005 0.2886 0.2828
Echinococcus multilocularis tensin 0.1395 0.4154 0.4107
Echinococcus multilocularis raf serine:threonine protein kinase 0.1005 0.2886 0.2828
Entamoeba histolytica protein kinase domain containing protein 0.101 0.2902 0.3804
Echinococcus multilocularis N chimaerin 0.1395 0.4154 0.4107
Trichomonas vaginalis TKL family protein kinase 0.1005 0.2886 1
Schistosoma mansoni tyrosine kinase 0.1005 0.2886 0.3818
Schistosoma mansoni ephrin receptor 0.1005 0.2886 0.3818
Echinococcus multilocularis retinal guanylyl cyclase 2 0.1005 0.2886 0.2828
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.1005 0.2886 0.3818
Entamoeba histolytica hypothetical protein, conserved 0.1005 0.2886 0.3782
Loa Loa (eye worm) hypothetical protein 0.1005 0.2886 0.2891
Trichomonas vaginalis TKL family protein kinase 0.1005 0.2886 1
Schistosoma mansoni tyrosine kinase 0.1005 0.2886 0.3818
Schistosoma mansoni serine/threonine protein kinase 0.1005 0.2886 0.3818
Trichomonas vaginalis TKL family protein kinase 0.1005 0.2886 1
Echinococcus granulosus apoptotic protease activating factor 1 0.025 0.0426 0.0348
Entamoeba histolytica serine/threonine kinase, putative 0.1005 0.2886 0.3782
Loa Loa (eye worm) TK protein kinase 0.1005 0.2886 0.2891
Trichomonas vaginalis TKL family protein kinase 0.1005 0.2886 1
Trypanosoma cruzi protein kinase, putative 0.1005 0.2886 0.994
Brugia malayi SH2 domain containing protein 0.1395 0.4154 0.5545
Trichomonas vaginalis TKL family protein kinase 0.1005 0.2886 1
Schistosoma mansoni protein kinase 0.101 0.2902 0.3841
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0183 0.0209 0.0307
Trichomonas vaginalis AGC family protein kinase 0.1005 0.2886 1
Loa Loa (eye worm) hypothetical protein 0.24 0.7428 0.7571
Loa Loa (eye worm) SRC-1 0.24 0.7428 0.7571
Echinococcus multilocularis tyrosine protein kinase shark 0.24 0.7428 0.7407
Echinococcus multilocularis suppressor of cytokine signaling 6 0.1395 0.4154 0.4107
Plasmodium vivax protein kinase, putative 0.1005 0.2886 1
Echinococcus granulosus signal transduction protein lnk realted 0.1395 0.4154 0.4107
Trichomonas vaginalis serine-threonine protein kinase, putative 0.1005 0.2886 1
Echinococcus multilocularis suppressor of cytokine signaling 7 0.1395 0.4154 0.4107
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.1005 0.2886 0.2828
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.1005 0.2886 0.2828
Loa Loa (eye worm) RGC/RGC protein kinase 0.1005 0.2886 0.2891
Schistosoma mansoni adapter molecule crk 0.1395 0.4154 0.5545
Loa Loa (eye worm) TK/FER protein kinase 0.24 0.7428 0.7571
Loa Loa (eye worm) hypothetical protein 0.1395 0.4154 0.4198
Loa Loa (eye worm) TK protein kinase 0.1005 0.2886 0.2891
Onchocerca volvulus 0.025 0.0426 0.0414
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.1005 0.2886 0.3782
Loa Loa (eye worm) hypothetical protein 0.1395 0.4154 0.4198
Onchocerca volvulus 0.1005 0.2886 0.3782
Brugia malayi Receptor family ligand binding region containing protein 0.1005 0.2886 0.3818
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.1395 0.4154 0.4107
Schistosoma mansoni tyrosine kinase 0.24 0.7428 1
Trichomonas vaginalis TKL family protein kinase 0.1005 0.2886 1
Trichomonas vaginalis TKL family protein kinase 0.1005 0.2886 1
Echinococcus granulosus activin receptor type 0.101 0.2902 0.2845
Entamoeba histolytica protein kinase, putative 0.1005 0.2886 0.3782
Onchocerca volvulus 0.24 0.7428 1
Schistosoma mansoni hypothetical protein 0.1395 0.4154 0.5545
Echinococcus granulosus protein kinase 0.1005 0.2886 0.2828
Schistosoma mansoni tensin 0.1395 0.4154 0.5545
Brugia malayi SH2 domain containing protein 0.24 0.7428 1
Loa Loa (eye worm) TK/FER protein kinase 0.24 0.7428 0.7571
Entamoeba histolytica ankyrin repeat protein 0.1005 0.2886 0.3782
Schistosoma mansoni suppressor of cytokine signaling 0.1395 0.4154 0.5545
Echinococcus granulosus cyclin B3 1 0.0157 0.0123 0.0044
Trichomonas vaginalis TKL family protein kinase 0.1005 0.2886 1
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.1005 0.2886 0.3782
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.1395 0.4154 0.4107
Onchocerca volvulus 0.1005 0.2886 0.3782
Loa Loa (eye worm) TK protein kinase 0.1005 0.2886 0.2891
Trichomonas vaginalis TKL family protein kinase 0.1005 0.2886 1
Echinococcus granulosus growth factor receptor bound protein 2 0.1395 0.4154 0.4107
Trichomonas vaginalis TKL family protein kinase 0.1005 0.2886 1
Echinococcus granulosus tyrosine protein kinase shark 0.24 0.7428 0.7407
Brugia malayi Immunoglobulin I-set domain containing protein 0.1005 0.2886 0.3818
Entamoeba histolytica tyrosin kinase, putative 0.1005 0.2886 0.3782
Echinococcus granulosus c src tyrosine kinase 0.24 0.7428 0.7407
Echinococcus multilocularis heat shock protein 70 0.1005 0.2886 0.2828
Entamoeba histolytica protein kinase, putative 0.1005 0.2886 0.3782
Entamoeba histolytica hypothetical protein 0.1005 0.2886 0.3782
Echinococcus multilocularis smoothened 0.319 1 1
Entamoeba histolytica protein kinase domain containing protein 0.1005 0.2886 0.3782
Echinococcus multilocularis integrin linked protein kinase 0.1005 0.2886 0.2828
Brugia malayi Cyclin, N-terminal domain containing protein 0.0157 0.0123 0.0059
Loa Loa (eye worm) TK/ACK protein kinase 0.1005 0.2886 0.2891
Schistosoma mansoni protein kinase 0.0839 0.2343 0.3079
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.1395 0.4154 0.4107
Loa Loa (eye worm) TK/FER protein kinase 0.24 0.7428 0.7571
Schistosoma mansoni tyrosine kinase 0.1005 0.2886 0.3818
Loa Loa (eye worm) hypothetical protein 0.1005 0.2886 0.2891
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.1005 0.2886 0.3782
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.1005 0.2886 0.2828
Brugia malayi Protein kinase domain containing protein 0.24 0.7428 1
Brugia malayi Protein kinase domain containing protein 0.1005 0.2886 0.3818
Trichomonas vaginalis TKL family protein kinase 0.1005 0.2886 1
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.24 0.7428 0.7407
Schistosoma mansoni tyrosine kinase 0.1005 0.2886 0.3818
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0183 0.0209 0.0129
Trichomonas vaginalis TKL family protein kinase 0.1005 0.2886 1
Trichomonas vaginalis TKL family protein kinase 0.1005 0.2886 1
Echinococcus multilocularis cyclins 0.0157 0.0123 0.0044
Giardia lamblia Kinase, NEK 0.1005 0.2886 1
Schistosoma mansoni tensin 0.1395 0.4154 0.5545
Brugia malayi Protein kinase domain containing protein 0.1005 0.2886 0.3818
Schistosoma mansoni shc transforming protein 0.1395 0.4154 0.5545
Schistosoma mansoni gamma-secretase subunit aph-1 0.0296 0.0575 0.0674
Echinococcus granulosus tyrosine protein kinase csk 0.1005 0.2886 0.2828
Trichomonas vaginalis TKL family protein kinase 0.1005 0.2886 1
Entamoeba histolytica hypothetical protein 0.1005 0.2886 0.3782
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0183 0.0209 0.0129
Onchocerca volvulus Tyrosine kinase homolog 0.1005 0.2886 0.3782
Trichomonas vaginalis TKL family protein kinase 0.1005 0.2886 1
Giardia lamblia Kinase, NEK 0.1005 0.2886 1
Echinococcus multilocularis natriuretic peptide receptor 1 0.1005 0.2886 0.2828
Schistosoma mansoni protein kinase 0.0839 0.2343 0.3079
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.1005 0.2886 0.2828
Onchocerca volvulus 0.1005 0.2886 0.3782
Entamoeba histolytica tyrosine kinase, putative 0.1005 0.2886 0.3782
Onchocerca volvulus 0.1005 0.2886 0.3782
Trichomonas vaginalis TKL family protein kinase 0.1005 0.2886 1
Brugia malayi Protein kinase domain containing protein 0.1005 0.2886 0.3818
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.1005 0.2886 0.9943
Trichomonas vaginalis TKL family protein kinase 0.1005 0.2886 1
Entamoeba histolytica protein kinase, putative 0.1005 0.2886 0.3782
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.101 0.2902 1
Entamoeba histolytica hypothetical protein 0.1005 0.2886 0.3782
Entamoeba histolytica hypothetical protein 0.1005 0.2886 0.3782
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0839 0.2343 0.2281
Brugia malayi Protein kinase domain containing protein 0.1005 0.2886 0.3818
Entamoeba histolytica protein kinase, putative 0.1005 0.2886 0.3782
Brugia malayi Protein kinase domain containing protein 0.1005 0.2886 0.3818
Echinococcus granulosus G2:mitotic specific cyclin B3 0.0157 0.0123 0.0044
Loa Loa (eye worm) cyclin domain-containing protein 0.0157 0.0123 0.0045
Echinococcus multilocularis retinal guanylyl cyclase 2 0.1005 0.2886 0.2828
Onchocerca volvulus 0.24 0.7428 1
Toxoplasma gondii protein kinase 0.1005 0.2886 0.9943
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.1005 0.2886 0.3782
Entamoeba histolytica tyrosine kinase, putative 0.1005 0.2886 0.3782
Loa Loa (eye worm) hypothetical protein 0.1005 0.2886 0.2891
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0183 0.0209 0.0129
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.1005 0.2886 0.2828
Onchocerca volvulus 0.1005 0.2886 0.3782
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.24 0.7428 0.7407
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.1005 0.2886 0.3782
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.1005 0.2886 0.2891
Schistosoma mansoni tyrosine kinase 0.1005 0.2886 0.3818
Loa Loa (eye worm) TK/FER protein kinase 0.24 0.7428 0.7571
Brugia malayi Protein kinase domain containing protein 0.1005 0.2886 0.3818
Brugia malayi Immunoglobulin I-set domain containing protein 0.1005 0.2886 0.3818
Entamoeba histolytica hypothetical protein 0.1005 0.2886 0.3782
Trichomonas vaginalis TKL family protein kinase 0.1005 0.2886 1
Loa Loa (eye worm) sex muscle abnormal protein 5 0.1395 0.4154 0.4198
Echinococcus granulosus hypothetical protein 0.1395 0.4154 0.4107
Loa Loa (eye worm) hypothetical protein 0.1395 0.4154 0.4198
Loa Loa (eye worm) hypothetical protein 0.1395 0.4154 0.4198
Trichomonas vaginalis TKL family protein kinase 0.1005 0.2886 1
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.24 0.7428 0.7407
Schistosoma mansoni SH2A 0.1395 0.4154 0.5545
Echinococcus multilocularis activated cdc42 kinase 1 0.1005 0.2886 0.2828
Trichomonas vaginalis TKL family protein kinase 0.1005 0.2886 1
Echinococcus granulosus caspase 2 0.0357 0.0775 0.0701
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.1005 0.2886 1
Brugia malayi Protein kinase domain containing protein 0.1005 0.2886 0.3818
Schistosoma mansoni tyrosine kinase 0.1005 0.2886 0.3818
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0839 0.2343 0.2281
Echinococcus granulosus tyrosine protein kinase 0.1005 0.2886 0.2828
Schistosoma mansoni protein tyrosine kinase 0.1005 0.2886 0.3818
Loa Loa (eye worm) hypothetical protein 0.3124 0.9785 1
Entamoeba histolytica protein kinase, putative 0.1005 0.2886 0.3782
Echinococcus multilocularis protein KINase family member (kin 25) 0.1005 0.2886 0.2828
Loa Loa (eye worm) TK/FER protein kinase 0.24 0.7428 0.7571
Schistosoma mansoni tyrosine kinase 0.1005 0.2886 0.3818
Brugia malayi Protein kinase domain containing protein 0.1005 0.2886 0.3818
Echinococcus granulosus tyrosine protein kinase Blk 0.24 0.7428 0.7407
Entamoeba histolytica protein kinase, putative 0.1005 0.2886 0.3782
Giardia lamblia Protein 21.1 0.1005 0.2886 1
Trichomonas vaginalis TKL family protein kinase 0.1005 0.2886 1
Loa Loa (eye worm) TK protein kinase 0.1005 0.2886 0.2891
Loa Loa (eye worm) TK protein kinase 0.1005 0.2886 0.2891
Loa Loa (eye worm) hypothetical protein 0.0157 0.0123 0.0045
Entamoeba histolytica tyrosine kinase, putative 0.1005 0.2886 0.3782
Trichomonas vaginalis TKL family protein kinase 0.1005 0.2886 1
Loa Loa (eye worm) TK protein kinase 0.1005 0.2886 0.2891
Schistosoma mansoni signal transduction protein lnk-related 0.1395 0.4154 0.5545
Entamoeba histolytica protein kinase domain containing protein 0.1005 0.2886 0.3782
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.1395 0.4154 0.4107
Trichomonas vaginalis TKL family protein kinase 0.1005 0.2886 1
Echinococcus multilocularis tyrosine protein kinase Fyn 0.24 0.7428 0.7407
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0178 0.0192 0.0113
Echinococcus granulosus cyclin b3 0.0157 0.0123 0.0044
Loa Loa (eye worm) TK protein kinase 0.24 0.7428 0.7571
Brugia malayi Protein kinase domain containing protein 0.1005 0.2886 0.3818
Echinococcus granulosus kinase suppressor of Ras 1 0.1005 0.2886 0.2828
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.1005 0.2886 0.3818
Trichomonas vaginalis TKL family protein kinase 0.1005 0.2886 1
Schistosoma mansoni tyrosine kinase 0.24 0.7428 1
Loa Loa (eye worm) hypothetical protein 0.1395 0.4154 0.4198
Leishmania major protein kinase, putative 0.1005 0.2886 0.994
Loa Loa (eye worm) hypothetical protein 0.1005 0.2886 0.2891
Brugia malayi Protein kinase domain containing protein 0.1005 0.2886 0.3818
Entamoeba histolytica protein kinase domain containing protein 0.1005 0.2886 0.3782
Echinococcus multilocularis growth factor receptor bound protein 2 0.1395 0.4154 0.4107
Entamoeba histolytica protein kinase, putative 0.1005 0.2886 0.3782
Brugia malayi Protein kinase domain containing protein 0.24 0.7428 1
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0183 0.0209 0.0175
Echinococcus multilocularis tyrosine protein kinase Abl 0.24 0.7428 0.7407
Trichomonas vaginalis TKL family protein kinase 0.1005 0.2886 1
Trichomonas vaginalis TKL family protein kinase 0.1005 0.2886 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.1005 0.2886 0.3782
Brugia malayi hypothetical protein 0.1005 0.2886 0.3818
Schistosoma mansoni protein kinase 0.101 0.2902 0.3841
Brugia malayi Protein kinase domain containing protein 0.1005 0.2886 0.3818
Plasmodium falciparum tyrosine kinase-like protein 0.1005 0.2886 0.994
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.24 0.7428 0.7407
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0183 0.0209 0.0129
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.1005 0.2886 0.3782
Schistosoma mansoni cyclins 0.0157 0.0123 0.0059
Loa Loa (eye worm) hypothetical protein 0.1395 0.4154 0.4198
Echinococcus granulosus tyrosine protein kinase pr2 0.1005 0.2886 0.2828
Schistosoma mansoni protein kinase 0.1005 0.2886 0.3818
Brugia malayi SH2 domain containing protein 0.1395 0.4154 0.5545
Loa Loa (eye worm) TK/DDR protein kinase 0.1005 0.2886 0.2891
Echinococcus multilocularis activin receptor type 0.101 0.2902 0.2845
Loa Loa (eye worm) RGC/RGC protein kinase 0.1005 0.2886 0.2891
Echinococcus multilocularis SHC transforming protein 3 0.1395 0.4154 0.4107
Brugia malayi Raf kinase 0.1005 0.2886 0.3818
Schistosoma mansoni serine/threonine protein kinase 0.0183 0.0209 0.0175
Trichomonas vaginalis TKL family protein kinase 0.1005 0.2886 1
Echinococcus granulosus SH2 domain containing protein 7 0.1395 0.4154 0.4107
Entamoeba histolytica protein kinase, putative 0.1005 0.2886 0.3782
Entamoeba histolytica protein kinase domain containing protein 0.1005 0.2886 0.3782
Schistosoma mansoni protein kinase 0.1005 0.2886 0.3818
Entamoeba histolytica hypothetical protein 0.1005 0.2886 0.3782
Schistosoma mansoni protein kinase 0.1005 0.2886 0.3818
Giardia lamblia Kinase, AGC PKA 0.0183 0.0209 0.0308
Brugia malayi SRC-1 0.24 0.7428 1
Entamoeba histolytica protein kinase domain containing protein 0.1005 0.2886 0.3782
Trichomonas vaginalis TKL family protein kinase 0.1005 0.2886 1
Loa Loa (eye worm) TK/EGFR protein kinase 0.1005 0.2886 0.2891
Echinococcus granulosus tyrosine kinase 0.24 0.7428 0.7407
Echinococcus granulosus cyclin B 0.0157 0.0123 0.0044
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.1005 0.2886 0.2891
Echinococcus multilocularis SH2 motif 0.1395 0.4154 0.4107
Loa Loa (eye worm) RGC/RGC protein kinase 0.1005 0.2886 0.2891
Loa Loa (eye worm) TK/FER protein kinase 0.24 0.7428 0.7571
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.1005 0.2886 0.2828
Entamoeba histolytica tyrosine kinase, putative 0.1005 0.2886 0.3782
Schistosoma mansoni tyrosine kinase 0.1005 0.2886 0.3818
Brugia malayi Protein kinase domain containing protein 0.1005 0.2886 0.3818
Echinococcus multilocularis cyclins 0.0157 0.0123 0.0044
Schistosoma mansoni tyrosine kinase 0.1005 0.2886 0.3818
Loa Loa (eye worm) TK/FER protein kinase 0.24 0.7428 0.7571
Entamoeba histolytica hypothetical protein 0.1005 0.2886 0.3782
Schistosoma mansoni tyrosine kinase 0.1005 0.2886 0.3818
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0734 0.2001 0.198
Entamoeba histolytica tyrosine kinase, putative 0.1005 0.2886 0.3782
Echinococcus multilocularis tyrosine protein kinase Blk 0.24 0.7428 0.7407
Plasmodium falciparum tyrosine kinase-like protein 0.1005 0.2886 0.994
Plasmodium falciparum protein kinase, putative 0.1005 0.2886 0.994
Echinococcus multilocularis tyrosine protein kinase Srms 0.24 0.7428 0.7407
Trichomonas vaginalis TKL family protein kinase 0.1005 0.2886 1
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0183 0.0209 0.0129
Echinococcus granulosus SHC transforming protein 3 0.1395 0.4154 0.4107
Trichomonas vaginalis TKL family protein kinase 0.1005 0.2886 1
Schistosoma mansoni protein kinase 0.1005 0.2886 0.3818
Plasmodium vivax tyrosine kinase-like protein, putative 0.1005 0.2886 1
Entamoeba histolytica protein kinase, putative 0.1005 0.2886 0.3782
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.1005 0.2886 0.2828
Entamoeba histolytica serine/threonine kinase, putative 0.1005 0.2886 0.3782
Echinococcus multilocularis tyrosine protein kinase csk 0.1005 0.2886 0.2828
Loa Loa (eye worm) hypothetical protein 0.1395 0.4154 0.4198
Schistosoma mansoni tyrosine kinase 0.24 0.7428 1
Trichomonas vaginalis TKL family protein kinase 0.1005 0.2886 1
Echinococcus multilocularis tyrosine protein kinase Fgr 0.24 0.7428 0.7407
Echinococcus granulosus fibroblast growth factor receptor 4 0.1005 0.2886 0.2828
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.24 0.7428 1
Brugia malayi Variant SH3 domain containing protein 0.1395 0.4154 0.5545
Entamoeba histolytica tyrosin kinase, putative 0.1005 0.2886 0.3782
Echinococcus multilocularis caspase 2 0.0357 0.0775 0.0701
Echinococcus multilocularis transfer RNA-Thr 0.1005 0.2886 0.2828
Echinococcus granulosus tyrosine protein kinase Fps85D 0.24 0.7428 0.7407
Plasmodium falciparum protein kinase, putative 0.1005 0.2886 0.994
Onchocerca volvulus 0.1005 0.2886 0.3782
Loa Loa (eye worm) hypothetical protein 0.1395 0.4154 0.4198
Trichomonas vaginalis TKL family protein kinase 0.1005 0.2886 1
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.24 0.7428 0.7407
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.1395 0.4154 0.4107
Echinococcus granulosus retinal guanylyl cyclase 2 0.1005 0.2886 0.2828
Brugia malayi Protein kinase domain containing protein 0.1005 0.2886 0.3818
Echinococcus granulosus cyclins 0.0157 0.0123 0.0044
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.1005 0.2886 0.3782
Toxoplasma gondii protein kinase domain-containing protein 0.1005 0.2886 0.9943
Brugia malayi hypothetical protein 0.025 0.0426 0.047
Loa Loa (eye worm) hypothetical protein 0.0183 0.0209 0.0132
Brugia malayi Protein kinase domain containing protein 0.1005 0.2886 0.3818
Schistosoma mansoni tyrosine kinase 0.1005 0.2886 0.3818
Trichomonas vaginalis TKL family protein kinase 0.1005 0.2886 1
Echinococcus multilocularis tyrosine protein kinase Fyn 0.24 0.7428 0.7407
Entamoeba histolytica SH2-protein kinase domain containing protein 0.14 0.4171 0.5541
Schistosoma mansoni tyrosine kinase 0.1005 0.2886 0.3818
Schistosoma mansoni serine/threonine RGC 0.1005 0.2886 0.3818
Entamoeba histolytica protein kinase domain containing protein 0.1005 0.2886 0.3782
Loa Loa (eye worm) TK/FER protein kinase 0.1005 0.2886 0.2891
Trichomonas vaginalis CAMK family protein kinase 0.1005 0.2886 1
Echinococcus granulosus activated cdc42 kinase 1 0.1005 0.2886 0.2828
Brugia malayi Cyclin, N-terminal domain containing protein 0.0157 0.0123 0.0059
Echinococcus multilocularis protein kinase 0.1005 0.2886 0.2828
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.1395 0.4154 0.4107
Loa Loa (eye worm) hypothetical protein 0.1005 0.2886 0.2891
Brugia malayi ephrin receptor 1 precursor 0.1005 0.2886 0.3818
Schistosoma mansoni tyrosine-protein kinase fps85d 0.1005 0.2886 0.3818
Brugia malayi Cyclin, N-terminal domain containing protein 0.0551 0.1405 0.1803
Echinococcus multilocularis epidermal growth factor receptor 0.1005 0.2886 0.2828
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.1005 0.2886 0.2891
Brugia malayi Probable tyrosine-protein kinase kin-31 0.1005 0.2886 0.3818
Echinococcus multilocularis insulin receptor 0.1005 0.2886 0.2828
Brugia malayi SH2 domain containing protein 0.1395 0.4154 0.5545
Onchocerca volvulus 0.24 0.7428 1
Echinococcus granulosus SH2 motif 0.1395 0.4154 0.4107
Echinococcus multilocularis tyrosine protein kinase Src42A 0.24 0.7428 0.7407
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.1005 0.2886 0.3782
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.1005 0.2886 0.3818
Echinococcus multilocularis NCK adaptor protein 0.1395 0.4154 0.4107
Echinococcus granulosus ephrin type A receptor 4 A 0.1005 0.2886 0.2828
Echinococcus multilocularis suppressor of cytokine signaling 7 0.1395 0.4154 0.4107
Schistosoma mansoni tyrosine-protein kinase fps85d 0.1005 0.2886 0.3818
Brugia malayi SH2 domain containing protein 0.1395 0.4154 0.5545
Schistosoma mansoni tyrosine-protein kinase zap-70 0.1395 0.4154 0.5545
Schistosoma mansoni caspase-7 (C14 family) 0.0357 0.0775 0.0946
Trichomonas vaginalis TKL family protein kinase 0.1005 0.2886 1
Trichomonas vaginalis TKL family protein kinase 0.1005 0.2886 1
Loa Loa (eye worm) RhoGAP domain-containing protein 0.1395 0.4154 0.4198
Loa Loa (eye worm) TK/ROR protein kinase 0.1005 0.2886 0.2891
Loa Loa (eye worm) hypothetical protein 0.1005 0.2886 0.2891
Echinococcus multilocularis tyrosine protein kinase Src42A 0.1395 0.4154 0.4107
Loa Loa (eye worm) hypothetical protein 0.1395 0.4154 0.4198
Echinococcus multilocularis cyclins 0.0157 0.0123 0.0044
Echinococcus multilocularis SH2 motif 0.1395 0.4154 0.4107
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.24 0.7428 0.7407
Echinococcus multilocularis cyclin B3 1 0.0157 0.0123 0.0044
Echinococcus granulosus tyrosine protein kinase Src42A 0.24 0.7428 0.7407
Schistosoma mansoni growth factor receptor-bound protein 0.1395 0.4154 0.5545
Trichomonas vaginalis TKL family protein kinase 0.1005 0.2886 1
Brugia malayi Protein kinase domain containing protein 0.24 0.7428 1
Echinococcus granulosus tyrosine protein kinase Btk29A 0.24 0.7428 0.7407
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.1005 0.2886 0.2828
Entamoeba histolytica hypothetical protein 0.1005 0.2886 0.3782
Loa Loa (eye worm) hypothetical protein 0.1005 0.2886 0.2891
Echinococcus granulosus tyrosine protein kinase Src64B 0.24 0.7428 0.7407
Echinococcus granulosus tyrosine protein kinase Btk29A 0.1005 0.2886 0.2828
Trichomonas vaginalis TKL family protein kinase 0.1005 0.2886 1
Entamoeba histolytica tyrosine kinase, putative 0.1005 0.2886 0.3782
Loa Loa (eye worm) hypothetical protein 0.1395 0.4154 0.4198
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0178 0.0192 0.0113
Echinococcus granulosus cyclins 0.0157 0.0123 0.0044
Brugia malayi hypothetical protein 0.1395 0.4154 0.5545
Loa Loa (eye worm) variant SH3 domain-containing protein 0.1395 0.4154 0.4198
Trichomonas vaginalis TKL family protein kinase 0.1005 0.2886 1
Entamoeba histolytica protein kinase domain containing protein 0.1005 0.2886 0.3782
Leishmania major protein kinase A catalytic subunit isoform 1 0.0183 0.0209 0.0307
Echinococcus granulosus SH2 motif 0.1395 0.4154 0.4107
Trichomonas vaginalis AGC family protein kinase 0.0183 0.0209 0.0308
Echinococcus granulosus NCK adaptor protein 0.1395 0.4154 0.4107
Loa Loa (eye worm) TK protein kinase 0.1005 0.2886 0.2891
Brugia malayi integrin-linked kinase 0.1005 0.2886 0.3818
Entamoeba histolytica serine/threonine kinase, putative 0.1005 0.2886 0.3782
Trichomonas vaginalis TKL family protein kinase 0.1005 0.2886 1
Onchocerca volvulus 0.1005 0.2886 0.3782
Onchocerca volvulus 0.1395 0.4154 0.5518
Trichomonas vaginalis TKL family protein kinase 0.1005 0.2886 1
Brugia malayi Tensin 0.1395 0.4154 0.5545
Brugia malayi tRNA modification GTPase TrmE family protein 0.1395 0.4154 0.5545
Entamoeba histolytica protein kinase domain containing protein 0.1005 0.2886 0.3782
Loa Loa (eye worm) hypothetical protein 0.0157 0.0123 0.0045

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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