TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 885.913 | Formula: C41H55N7O15
H donors: 12 H acceptors: 15 LogP: -0.19 Rotable bonds: 32
Rule of 5 violations (Lipinski): 4
SMILES: Oc1cccc(c1)C[C@@H](C(=O)O)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H]([C@@H](O)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)C)CC(C)C)CC(=O)O)C)CC(=O)O
InChi: 1S/C41H55N7O15/c1-20(2)14-27(46-40(61)34(22(4)49)48-39(60)28(43-23(5)50)16-24-10-7-6-8-11-24)37(58)45-29(18-32(52)53)36(57)42-21(3)35(56)44-30(19-33(54)55)38(59)47-31(41(62)63)17-25-12-9-13-26(51)15-25/h6-13,15,20-22,27-31,34,49,51H,14,16-19H2,1-5H3,(H,42,57)(H,43,50)(H,44,56)(H,45,58)(H,46,61)(H,47,59)(H,48,60)(H,52,53)(H,54,55)(H,62,63)/t21-,22-,27-,28-,29-,30-,31-,34-/m0/s1
InChiKey: MBPDQSFUNXEDIF-AUEPOHOQSA-N

Network

Hover on a compound node to display the structore

Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

This is a work in progress. Come back soon to try this features!

Clustering layers

This is a work in progress. Come back soon to try this features!

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Trichomonas vaginalis	TKL family protein kinase	0.0326	0.431	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0326	0.431	0.5
Schistosoma mansoni	tyrosine kinase	0.0326	0.431	0.3227
Brugia malayi	Protein kinase domain containing protein	0.0326	0.431	0.3908
Onchocerca volvulus		0.0206	0.1671	0.1679
Schistosoma mansoni	tyrosine kinase	0.0326	0.431	0.3227
Onchocerca volvulus	Suppressor of cytokine signaling at 36E homolog	0.0255	0.276	0.2773
Schistosoma mansoni	tyrosine kinase	0.0326	0.431	0.3227
Echinococcus granulosus	ephrin type A receptor 4 A	0.0326	0.431	0.4053
Schistosoma mansoni	serine/threonine protein kinase	0.0304	0.3838	0.2661
Echinococcus multilocularis	macrophage colony stimulating factor 1 receptor	0.0326	0.431	0.3081
Brugia malayi	Protein kinase domain containing protein	0.0326	0.431	0.3908
Trichomonas vaginalis	conserved hypothetical protein	0.0326	0.431	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0326	0.431	0.5
Brugia malayi	Tensin	0.0255	0.276	0.2234
Entamoeba histolytica	protein kinase domain containing protein	0.0326	0.431	0.4012
Loa Loa (eye worm)	hypothetical protein	0.0206	0.1671	0.1679
Onchocerca volvulus		0.0255	0.276	0.2773
Entamoeba histolytica	SH2-protein kinase domain containing protein	0.0258	0.2808	0.2418
Echinococcus granulosus	tyrosine protein kinase csk	0.0326	0.431	0.4053
Brugia malayi	Variant SH3 domain containing protein	0.0255	0.276	0.2234
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0581	0.9952	1
Schistosoma mansoni	tyrosine kinase	0.0326	0.431	0.3227
Loa Loa (eye worm)	hypothetical protein	0.0255	0.276	0.2773
Schistosoma mansoni	adapter molecule crk	0.0255	0.276	0.1366
Entamoeba histolytica	tyrosine kinase, putative	0.0326	0.431	0.4012
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0326	0.431	0.3908
Schistosoma mansoni	protein kinase	0.0326	0.431	0.3227
Loa Loa (eye worm)	hypothetical protein	0.0255	0.276	0.2773
Echinococcus multilocularis	tyrosine protein kinase Fgr	0.0581	0.9952	1
Schistosoma mansoni	tyrosine kinase	0.0326	0.431	0.3227
Loa Loa (eye worm)	TK protein kinase	0.0326	0.431	0.4331
Onchocerca volvulus	Suppressor of cytokine signaling 7 homolog	0.0255	0.276	0.2773
Brugia malayi	protein-tyrosine kinase	0.0581	0.9952	1
Echinococcus granulosus	suppressor of cytokine signaling 7	0.0255	0.276	0.2432
Loa Loa (eye worm)	TK/FER protein kinase	0.0326	0.431	0.4331
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0326	0.431	0.4012
Entamoeba histolytica	protein kinase domain containing protein	0.0326	0.431	0.4012
Trichomonas vaginalis	TKL family protein kinase	0.0326	0.431	0.5
Trypanosoma cruzi	STE/STE11 serine/threonine-protein kinase, putative	0.0328	0.4358	1
Trichomonas vaginalis	TKL family protein kinase	0.0326	0.431	0.5
Echinococcus granulosus	activin receptor type	0.0328	0.4358	0.4103
Entamoeba histolytica	protein kinase, putative	0.0326	0.431	0.4012
Loa Loa (eye worm)	TKL/MLK/HH498 protein kinase	0.0326	0.431	0.4331
Schistosoma mansoni	tyrosine kinase	0.0326	0.431	0.3227
Echinococcus multilocularis	tyrosine protein kinase Btk29A	0.0581	0.9952	1
Onchocerca volvulus		0.0326	0.431	0.4331
Brugia malayi	Guanylyl cyclase protein 23	0.0326	0.431	0.3908
Entamoeba histolytica	tyrosine kinase, putative	0.0326	0.431	0.4012
Trichomonas vaginalis	TKL family protein kinase	0.0326	0.431	0.5
Schistosoma mansoni	serine/threonine protein kinase	0.0326	0.431	0.3227
Echinococcus multilocularis	protein kinase c iota type	0.0238	0.2374	0.0707
Brugia malayi	Protein kinase c protein 2	0.0207	0.1689	0.1077
Brugia malayi	Protein kinase domain containing protein	0.0581	0.9952	1
Schistosoma mansoni	nck2/grb4	0.0255	0.276	0.1366
Echinococcus granulosus	melanoma receptor tyrosine protein kinase	0.0326	0.431	0.4053
Loa Loa (eye worm)	SRC-1	0.0581	0.9952	1
Echinococcus granulosus	SH2 domain containing protein 7	0.0255	0.276	0.2432
Echinococcus granulosus	proto oncogene tyrosine protein kinase LCK	0.0581	0.9952	0.995
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0326	0.431	0.4012
Brugia malayi	Protein kinase domain containing protein	0.0326	0.431	0.3908
Echinococcus multilocularis	FL cytokine receptor	0.0326	0.431	0.3081
Loa Loa (eye worm)	TK protein kinase	0.0326	0.431	0.4331
Schistosoma mansoni	tyrosine protein kinase	0.0326	0.431	0.3227
Echinococcus granulosus	tyrosine protein kinase HCK	0.0326	0.431	0.4053
Loa Loa (eye worm)	hypothetical protein	0.0326	0.431	0.4331
Trichomonas vaginalis	TKL family protein kinase	0.0326	0.431	0.5
Echinococcus granulosus	NCK adaptor protein	0.0255	0.276	0.2432
Onchocerca volvulus		0.0255	0.276	0.2773
Brugia malayi	Variant SH3 domain containing protein	0.0327	0.4334	0.3933
Trichomonas vaginalis	TKL family protein kinase	0.0326	0.431	0.5
Onchocerca volvulus		0.0581	0.9952	1
Loa Loa (eye worm)	hypothetical protein	0.0326	0.431	0.4331
Echinococcus granulosus	3'partial\|retinal guanylyl cyclase 2	0.0326	0.431	0.4053
Brugia malayi	SH2 domain containing protein	0.0581	0.9952	1
Entamoeba histolytica	protein kinase, putative	0.0326	0.431	0.4012
Loa Loa (eye worm)	TK/EPH protein kinase	0.0326	0.431	0.4331
Entamoeba histolytica	tyrosin kinase, putative	0.0326	0.431	0.4012
Trichomonas vaginalis	TKL family protein kinase	0.0326	0.431	0.5
Brugia malayi	Tyrosine-protein kinase abl-1	0.0581	0.9952	1
Loa Loa (eye worm)	TK/CSK protein kinase	0.0326	0.431	0.4331
Trichomonas vaginalis	TKL family protein kinase	0.0326	0.431	0.5
Echinococcus granulosus	3'partial\|tyrosine protein kinase Fgr	0.0581	0.9952	0.995
Loa Loa (eye worm)	TKL/RAF/KSR protein kinase	0.0326	0.431	0.4331
Giardia lamblia	Kinase	0.0326	0.431	0.5
Loa Loa (eye worm)	TK/FER protein kinase	0.0581	0.9952	1
Onchocerca volvulus		0.0581	0.9952	1
Onchocerca volvulus		0.0326	0.431	0.4331
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0326	0.431	0.4012
Entamoeba histolytica	protein kinase, putative	0.0326	0.431	0.4012
Entamoeba histolytica	protein kinase domain containing protein	0.0326	0.431	0.4012
Echinococcus multilocularis	activated cdc42 kinase 1	0.0326	0.431	0.3081
Brugia malayi	Protein kinase domain containing protein	0.0326	0.431	0.3908
Entamoeba histolytica	hypothetical protein	0.0326	0.431	0.4012
Onchocerca volvulus		0.0326	0.431	0.4331
Loa Loa (eye worm)	TK/FER protein kinase	0.0581	0.9952	1
Trichomonas vaginalis	TKL family protein kinase	0.0326	0.431	0.5
Brugia malayi	Protein kinase domain containing protein	0.0326	0.431	0.3908
Schistosoma mansoni	protein kinase	0.0326	0.431	0.3227
Onchocerca volvulus		0.0326	0.431	0.4331
Brugia malayi	SH2 domain containing protein	0.0255	0.276	0.2234
Loa Loa (eye worm)	TK/FER protein kinase	0.0326	0.431	0.4331
Echinococcus granulosus	tyrosine protein kinase shark	0.0581	0.9952	0.995
Trichomonas vaginalis	TKL family protein kinase	0.0326	0.431	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0326	0.431	0.5
Trichomonas vaginalis	serine-threonine protein kinase, putative	0.0326	0.431	0.5
Entamoeba histolytica	tyrosine kinase, putative	0.0326	0.431	0.4012
Echinococcus granulosus	macrophage colony stimulating factor 1 receptor	0.0326	0.431	0.4053
Echinococcus granulosus	raf serine:threonine protein kinase	0.0397	0.5884	0.5698
Brugia malayi	SH2 domain containing protein	0.0255	0.276	0.2234
Entamoeba histolytica	serine/threonine kinase, putative	0.0326	0.431	0.4012
Entamoeba histolytica	protein kinase, putative	0.0326	0.431	0.4012
Schistosoma mansoni	tensin-related	0.0255	0.276	0.1366
Echinococcus multilocularis	activin receptor type	0.0328	0.4358	0.314
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0581	0.9952	1
Echinococcus multilocularis	tyrosine protein kinase Fps85D	0.0581	0.9952	1
Trypanosoma brucei	protein kinase, putative	0.0328	0.4358	1
Brugia malayi	Protein kinase domain containing protein	0.0326	0.431	0.3908
Trichomonas vaginalis	serine/threonine-protein kinase wnk, putative	0.0326	0.431	0.5
Brugia malayi	Raf kinase	0.0326	0.431	0.3908
Loa Loa (eye worm)	TKL/STKR/TYPE1 protein kinase	0.0326	0.431	0.4331
Loa Loa (eye worm)	TK/INSR protein kinase	0.0326	0.431	0.4331
Trichomonas vaginalis	TKL family protein kinase	0.0326	0.431	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0326	0.431	0.5
Loa Loa (eye worm)	protein kinase domain-containing protein	0.0326	0.431	0.4331
Echinococcus multilocularis	tyrosine protein kinase Src42A	0.0255	0.276	0.118
Entamoeba histolytica	hypothetical protein	0.0326	0.431	0.4012
Echinococcus multilocularis	tyrosine protein kinase Srms	0.0581	0.9952	1
Onchocerca volvulus		0.0581	0.9952	1
Echinococcus granulosus	insulin growth factor 1 receptor beta	0.0326	0.431	0.4053
Onchocerca volvulus		0.0255	0.276	0.2773
Echinococcus granulosus	tensin C1 domain containing phosphatase	0.0255	0.276	0.2432
Brugia malayi	Protein kinase domain containing protein	0.0326	0.431	0.3908
Brugia malayi	SH2 domain containing protein	0.0255	0.276	0.2234
Schistosoma mansoni	tyrosine kinase	0.0581	0.9952	1
Entamoeba histolytica	protein kinase, putative	0.0326	0.431	0.4012
Schistosoma mansoni	serine/threonine protein kinase	0.0397	0.5884	0.5117
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0326	0.431	0.4012
Brugia malayi	ephrin receptor 1 precursor	0.0326	0.431	0.3908
Echinococcus granulosus	protein kinase C gamma type	0.0212	0.1798	0.1427
Loa Loa (eye worm)	TK/FER protein kinase	0.0581	0.9952	1
Schistosoma mansoni	suppressor of cytokine signaling	0.0255	0.276	0.1366
Echinococcus multilocularis	SHC transforming protein 3	0.0255	0.276	0.118
Loa Loa (eye worm)	TK/FAK protein kinase	0.0326	0.431	0.4331
Echinococcus granulosus	epidermal growth factor receptor	0.0326	0.431	0.4053
Loa Loa (eye worm)	TK/FER protein kinase	0.0581	0.9952	1
Loa Loa (eye worm)	TKL/MLK/ILK protein kinase	0.0326	0.431	0.4331
Echinococcus multilocularis	basic fibroblast growth factor receptor 1 A	0.0326	0.431	0.3081
Brugia malayi	Variant SH3 domain containing protein	0.0266	0.3006	0.2499
Trichomonas vaginalis	TKL family protein kinase	0.0326	0.431	0.5
Echinococcus multilocularis	mitogen activated protein kinase kinase kinase	0.0326	0.431	0.3081
Entamoeba histolytica	receptor protein kinase, putative	0.0326	0.431	0.4012
Trichomonas vaginalis	TKL family protein kinase	0.0326	0.431	0.5
Entamoeba histolytica	ankyrin repeat protein	0.0326	0.431	0.4012
Trichomonas vaginalis	protein tyrosine kinase, putative	0.0326	0.431	0.5
Onchocerca volvulus		0.0255	0.276	0.2773
Trichomonas vaginalis	TKL family protein kinase	0.0326	0.431	0.5
Loa Loa (eye worm)	hypothetical protein	0.0255	0.276	0.2773
Trichomonas vaginalis	TKL family protein kinase	0.0326	0.431	0.5
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0581	0.9952	0.995
Echinococcus granulosus	mitogen activated protein kinase kinase kinase	0.0326	0.431	0.4053
Loa Loa (eye worm)	variant SH3 domain-containing protein	0.0266	0.3006	0.302
Entamoeba histolytica	protein kinase domain containing protein	0.0326	0.431	0.4012
Entamoeba histolytica	protein kinase domain containing protein	0.0326	0.431	0.4012
Echinococcus granulosus	tyrosine protein kinase csk	0.0326	0.431	0.4053
Loa Loa (eye worm)	hypothetical protein	0.0367	0.5226	0.5251
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0326	0.431	0.4012
Loa Loa (eye worm)	TK/FER protein kinase	0.0581	0.9952	1
Loa Loa (eye worm)	hypothetical protein	0.0326	0.431	0.4331
Echinococcus granulosus	tyrosine protein kinase transmembrane receptor	0.0326	0.431	0.4053
Loa Loa (eye worm)	hypothetical protein	0.0255	0.276	0.2773
Entamoeba histolytica	tyrosine kinase, putative	0.0326	0.431	0.4012
Loa Loa (eye worm)	TK/RYK protein kinase	0.0326	0.431	0.4331
Brugia malayi	Protein kinase domain containing protein	0.0326	0.431	0.3908
Loa Loa (eye worm)	hypothetical protein	0.0255	0.276	0.2773
Echinococcus granulosus	mitogen-activated protein kinase kinase kinase 9	0.0326	0.431	0.4053
Brugia malayi	Protein kinase domain containing protein	0.0326	0.431	0.3908
Echinococcus granulosus	tyrosine protein kinase	0.0326	0.431	0.4053
Entamoeba histolytica	tyrosin kinase, putative	0.0326	0.431	0.4012
Echinococcus granulosus	tyrosine protein kinase csk	0.0326	0.431	0.4053
Schistosoma mansoni	ephrin receptor	0.0326	0.431	0.3227
Loa Loa (eye worm)	hypothetical protein	0.0202	0.1574	0.1581
Loa Loa (eye worm)	TK protein kinase	0.0326	0.431	0.4331
Echinococcus granulosus	natriuretic peptide receptor 1	0.0326	0.431	0.4053
Trichomonas vaginalis	br serine/threonine-protein kinase, putative	0.0326	0.431	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0326	0.431	0.5
Echinococcus multilocularis	tyrosine protein kinase Src42A	0.0581	0.9952	1
Brugia malayi	Protein kinase domain containing protein	0.0581	0.9952	1
Entamoeba histolytica	protein kinase, putative	0.0326	0.431	0.4012
Loa Loa (eye worm)	AGC/PKC/ETA protein kinase	0.0304	0.3838	0.3857
Entamoeba histolytica	tyrosine kinase, putative	0.0326	0.431	0.4012
Echinococcus multilocularis	tensin	0.0255	0.276	0.118
Schistosoma mansoni	protein kinase	0.0328	0.4358	0.3285
Trichomonas vaginalis	TKL family protein kinase	0.0326	0.431	0.5
Entamoeba histolytica	ankyrin repeat protein	0.0326	0.431	0.4012
Entamoeba histolytica	protein kinase domain containing protein	0.0326	0.431	0.4012
Trichomonas vaginalis	TKL family protein kinase	0.0326	0.431	0.5
Loa Loa (eye worm)	serine/threonine protein kinase	0.0326	0.431	0.4331
Echinococcus multilocularis	kinase suppressor of Ras 1	0.0326	0.431	0.3081
Trichomonas vaginalis	TKL family protein kinase	0.0326	0.431	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0326	0.431	0.5
Echinococcus granulosus	epidermal growth factor receptor	0.0326	0.431	0.4053
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0326	0.431	0.4331
Schistosoma mansoni	protein kinase	0.0328	0.4358	0.3285
Echinococcus granulosus	tyrosine kinase	0.0581	0.9952	0.995
Entamoeba histolytica	protein kinase domain containing protein	0.0328	0.4358	0.4063
Loa Loa (eye worm)	TK/FER protein kinase	0.0581	0.9952	1
Echinococcus granulosus	tyrosine kinase	0.0581	0.9952	0.995
Loa Loa (eye worm)	hypothetical protein	0.0326	0.431	0.4331
Schistosoma mansoni	tyrosine kinase	0.0326	0.431	0.3227
Echinococcus multilocularis	tyrosine protein kinase shark	0.0581	0.9952	1
Brugia malayi	Protein kinase domain containing protein	0.0326	0.431	0.3908
Echinococcus multilocularis	c src tyrosine kinase	0.0581	0.9952	1
Loa Loa (eye worm)	TK/ROR protein kinase	0.0326	0.431	0.4331
Echinococcus multilocularis	guanine nucleotide exchange factor VAV2	0.0327	0.4334	0.311
Entamoeba histolytica	SH2 domain containing protein	0.0255	0.276	0.2367
Echinococcus multilocularis	tyrosine protein kinase csk	0.0326	0.431	0.3081
Schistosoma mansoni	tyrosine-protein kinase zap-70	0.0255	0.276	0.1366
Schistosoma mansoni	vav2	0.0331	0.4431	0.3372
Entamoeba histolytica	protein kinase domain containing protein	0.0326	0.431	0.4012
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.0326	0.431	0.3081
Onchocerca volvulus		0.0326	0.431	0.4331
Trichomonas vaginalis	TKL family protein kinase	0.0326	0.431	0.5
Echinococcus multilocularis	tyrosine protein kinase pr2	0.0326	0.431	0.3081
Schistosoma mansoni	tensin	0.0255	0.276	0.1366
Onchocerca volvulus		0.0296	0.3652	0.3669
Echinococcus multilocularis	mitogen activated protein kinase kinase kinase	0.0326	0.431	0.3081
Schistosoma mansoni	tensin	0.0255	0.276	0.1366
Echinococcus multilocularis	ephrin type A receptor 4 A	0.0326	0.431	0.3081
Onchocerca volvulus		0.0255	0.276	0.2773
Entamoeba histolytica	protein kinase domain containing protein	0.0326	0.431	0.4012
Onchocerca volvulus	Tyrosine kinase homolog	0.0326	0.431	0.4331
Trichomonas vaginalis	TKL family protein kinase	0.0326	0.431	0.5
Entamoeba histolytica	tyrosin kinase, putative	0.0326	0.431	0.4012
Echinococcus granulosus	phosphatidylinositol 3 kinase regulatory subunit	0.0255	0.276	0.2432
Loa Loa (eye worm)	SH2 domain-containing protein	0.0255	0.276	0.2773
Onchocerca volvulus		0.0326	0.431	0.4331
Entamoeba histolytica	serine/threonine kinase, putative	0.0326	0.431	0.4012
Echinococcus granulosus	tyrosine protein kinase pr2	0.0326	0.431	0.4053
Plasmodium vivax	tyrosine kinase-like protein, putative	0.0326	0.431	0.5
Echinococcus granulosus	tyrosine protein kinase Src42A	0.0581	0.9952	0.995
Brugia malayi	Protein kinase domain containing protein	0.0581	0.9952	1
Loa Loa (eye worm)	hypothetical protein	0.0255	0.276	0.2773
Echinococcus multilocularis	insulin receptor	0.0326	0.431	0.3081
Echinococcus multilocularis	epidermal growth factor receptor	0.0326	0.431	0.3081
Echinococcus granulosus	atrial natriuretic peptide receptor 1	0.0326	0.431	0.4053
Echinococcus granulosus	basic fibroblast growth factor receptor 1 A	0.0326	0.431	0.4053
Giardia lamblia	Kinase, NEK	0.0326	0.431	0.5
Loa Loa (eye worm)	hypothetical protein	0.0296	0.3652	0.3669
Echinococcus granulosus	tyrosine kinase\|tyrosine protein kinase Fyn	0.0581	0.9952	0.995
Schistosoma mansoni	tensin	0.0255	0.276	0.1366
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0326	0.431	0.4012
Brugia malayi	integrin-linked kinase	0.0326	0.431	0.3908
Trypanosoma cruzi	STE/STE11 serine/threonine-protein kinase, putative	0.0328	0.4358	1
Giardia lamblia	Protein 21.1	0.0326	0.431	0.5
Trichomonas vaginalis	conserved hypothetical protein	0.0326	0.431	0.5
Schistosoma mansoni	protein kinase	0.0326	0.431	0.3227
Trichomonas vaginalis	TKL family protein kinase	0.0326	0.431	0.5
Entamoeba histolytica	protein kinase, putative	0.0326	0.431	0.4012
Brugia malayi	Tyrosine-protein kinase PR2	0.0326	0.431	0.3908
Loa Loa (eye worm)	TK protein kinase	0.0326	0.431	0.4331
Trichomonas vaginalis	TKL family protein kinase	0.0326	0.431	0.5
Loa Loa (eye worm)	protein-tyrosine phosphatase	0.0255	0.276	0.2773
Loa Loa (eye worm)	hypothetical protein	0.0255	0.276	0.2773
Entamoeba histolytica	tyrosine kinase, putative	0.0326	0.431	0.4012
Echinococcus multilocularis	suppressor of cytokine signaling 7	0.0255	0.276	0.118
Entamoeba histolytica	protein kinase, putative	0.0326	0.431	0.4012
Loa Loa (eye worm)	TK protein kinase	0.0326	0.431	0.4331
Schistosoma mansoni	tyrosine kinase	0.0581	0.9952	1
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0255	0.276	0.2234
Brugia malayi	Protein kinase domain containing protein	0.0581	0.9952	1
Brugia malayi	Probable tyrosine-protein kinase kin-31	0.0326	0.431	0.3908
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0581	0.9952	0.995
Trichomonas vaginalis	ankyrin repeat-containing protein, putative	0.0326	0.431	0.5
Schistosoma mansoni	tyrosine kinase	0.0326	0.431	0.3227
Brugia malayi	Protein kinase domain containing protein	0.0326	0.431	0.3908
Loa Loa (eye worm)	SH2 domain-containing protein	0.0255	0.276	0.2773
Schistosoma mansoni	tyrosine kinase	0.0326	0.431	0.3227
Schistosoma mansoni	growth factor receptor-bound protein	0.0255	0.276	0.1366
Echinococcus granulosus	protein kinase c iota type	0.0238	0.2374	0.2029
Echinococcus multilocularis	proto oncogene tyrosine protein kinase LCK	0.0581	0.9952	1
Echinococcus granulosus	retinal guanylyl cyclase 2	0.0326	0.431	0.4053
Echinococcus granulosus	retinal guanylyl cyclase 2	0.0326	0.431	0.4053
Brugia malayi	Phorbol esters/diacylglycerol binding domain	0.0204	0.1622	0.1005
Brugia malayi	Protein kinase domain containing protein	0.0326	0.431	0.3908
Brugia malayi	cytokine inducible SH2-containing protein 5	0.0255	0.276	0.2234
Echinococcus granulosus	tyrosine protein kinase Srms	0.0581	0.9952	0.995
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0326	0.431	0.4331
Loa Loa (eye worm)	TK/FER protein kinase	0.0581	0.9952	1
Entamoeba histolytica	protein kinase domain containing protein	0.0326	0.431	0.4012
Entamoeba histolytica	cysteine surface protein, putative	0.0326	0.431	0.4012
Trichomonas vaginalis	TKL family protein kinase	0.0326	0.431	0.5
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0326	0.431	0.4012
Entamoeba histolytica	serine/threonine kinase, putative	0.0326	0.431	0.4012
Echinococcus multilocularis	epidermal growth factor receptor	0.0326	0.431	0.3081
Echinococcus multilocularis	tyrosine protein phosphatase non receptor type	0.0255	0.276	0.118
Brugia malayi	Adenylate and Guanylate cyclase catalytic domain containing protein	0.0326	0.431	0.3908
Echinococcus granulosus	suppressor of cytokine signaling 6	0.0255	0.276	0.2432
Schistosoma mansoni	proto-oncogene tyrosine-protein kinase src	0.0326	0.431	0.3227
Entamoeba histolytica	tyrosine kinase, putative	0.0326	0.431	0.4012
Echinococcus multilocularis	tyrosine protein kinase Abl	0.0581	0.9952	1
Trichomonas vaginalis	conserved hypothetical protein	0.0326	0.431	0.5
Schistosoma mansoni	tyrosine kinase	0.0581	0.9952	1
Trichomonas vaginalis	TKL family protein kinase	0.0326	0.431	0.5
Loa Loa (eye worm)	CAMK/PKD protein kinase	0.0133	0.0048	0.0048
Brugia malayi	Variant SH3 domain containing protein	0.0255	0.276	0.2234
Entamoeba histolytica	protein kinase domain containing protein	0.0326	0.431	0.4012
Brugia malayi	SH2 domain containing protein	0.0581	0.9952	1
Brugia malayi	Protein kinase domain containing protein	0.0326	0.431	0.3908
Echinococcus granulosus	retinal guanylyl cyclase 2	0.0326	0.431	0.4053
Echinococcus granulosus	protein tyrosine kinase	0.0326	0.431	0.4053
Echinococcus granulosus	tyrosine protein kinase ABL1	0.0581	0.9952	0.995
Echinococcus multilocularis	tyrosine protein kinase HCK	0.0326	0.431	0.3081
Schistosoma mansoni	chimerin-related rho-gtpase-activating protein	0.0327	0.4334	0.3255
Echinococcus granulosus	tyrosine protein kinase Src64B	0.0581	0.9952	0.995
Trichomonas vaginalis	TKL family protein kinase	0.0326	0.431	0.5
Echinococcus granulosus	SH2 motif	0.0255	0.276	0.2432
Echinococcus multilocularis	tyrosine kinase	0.0581	0.9952	1
Schistosoma mansoni	tyrosine kinase	0.0581	0.9952	1
Entamoeba histolytica	hypothetical protein	0.0326	0.431	0.4012
Echinococcus multilocularis	tyrosine kinase	0.0326	0.431	0.3081
Loa Loa (eye worm)	TK/FER protein kinase	0.0326	0.431	0.4331
Loa Loa (eye worm)	TK protein kinase	0.0326	0.431	0.4331
Schistosoma mansoni	tyrosine kinase	0.0581	0.9952	1
Schistosoma mansoni	proto-oncogene tyrosine-protein kinase src	0.0581	0.9952	1
Trichomonas vaginalis	TKL family protein kinase	0.0326	0.431	0.5
Schistosoma mansoni	serine/threonine protein kinase	0.0326	0.431	0.3227
Echinococcus multilocularis	SH2 motif	0.0255	0.276	0.118
Plasmodium falciparum	protein kinase, putative	0.0328	0.4358	1
Brugia malayi	Protein kinase domain containing protein	0.0326	0.431	0.3908
Loa Loa (eye worm)	TK protein kinase	0.0326	0.431	0.4331
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.0326	0.431	0.3081
Onchocerca volvulus		0.0255	0.276	0.2773
Entamoeba histolytica	protein kinase, putative	0.0326	0.431	0.4012
Brugia malayi	hypothetical protein	0.0326	0.431	0.3908
Entamoeba histolytica	protein kinase, putative	0.0326	0.431	0.4012
Brugia malayi	SH2 domain containing protein	0.0255	0.276	0.2234
Echinococcus multilocularis	dual specificity testis specific protein kinase	0.0328	0.4358	0.314
Schistosoma mansoni	tyrosine protein kinase fes (fps) (ptk group IV)	0.0326	0.431	0.3227
Echinococcus multilocularis	protein kinase c epsilon type	0.0304	0.3838	0.2502
Entamoeba histolytica	protein kinase domain containing protein	0.0326	0.431	0.4012
Brugia malayi	Receptor family ligand binding region containing protein	0.0326	0.431	0.3908
Entamoeba histolytica	tyrosine kinase, putative	0.0326	0.431	0.4012
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0326	0.431	0.4012
Schistosoma mansoni	protein kinase	0.0326	0.431	0.3227
Entamoeba histolytica	tyrosine kinase, putative	0.0326	0.431	0.4012
Trypanosoma brucei	STE/STE11 serine/threonine-protein kinase, putative	0.0328	0.4358	1
Entamoeba histolytica	protein kinase, putative	0.0326	0.431	0.4012
Schistosoma mansoni	tyrosine kinase	0.0326	0.431	0.3227
Loa Loa (eye worm)	TK/FER protein kinase	0.0581	0.9952	1
Schistosoma mansoni	tyrosine kinase	0.0326	0.431	0.3227
Schistosoma mansoni	tyrosine kinase	0.0326	0.431	0.3227
Echinococcus multilocularis	tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase	0.0581	0.9952	1
Echinococcus granulosus	SH2 motif	0.0255	0.276	0.2432
Echinococcus granulosus	integrin linked protein kinase	0.0326	0.431	0.4053
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0326	0.431	0.4012
Trichomonas vaginalis	TK family protein kinase	0.0326	0.431	0.5
Trichomonas vaginalis	protein kinase atn1, putative	0.0326	0.431	0.5
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0326	0.431	0.4012
Echinococcus granulosus	signal transduction protein lnk realted	0.0255	0.276	0.2432
Echinococcus granulosus	hypothetical protein	0.0255	0.276	0.2432
Brugia malayi	protein kinase C II.	0.0304	0.3838	0.3398
Echinococcus multilocularis	Protein kinase C, brain isozyme	0.0283	0.3372	0.193
Echinococcus multilocularis	transfer RNA-Thr	0.0326	0.431	0.3081
Echinococcus granulosus	dual specificity testis-specific protein kinase	0.0328	0.4358	0.4103
Entamoeba histolytica	protein kinase, putative	0.0258	0.2808	0.2418
Schistosoma mansoni	tyrosine kinase	0.0326	0.431	0.3227
Brugia malayi	proto-oncogene tyrosine-protein kinase FER	0.0326	0.431	0.3908
Loa Loa (eye worm)	TK protein kinase	0.0581	0.9952	1
Loa Loa (eye worm)	AGC/PKC/ALPHA protein kinase	0.0136	0.0115	0.0115
Echinococcus multilocularis	integrin linked protein kinase	0.0326	0.431	0.3081
Loa Loa (eye worm)	hypothetical protein	0.026	0.2857	0.2871
Echinococcus granulosus	SH2 domain containing adapter protein F	0.0255	0.276	0.2432
Trichomonas vaginalis	TKL family protein kinase	0.0326	0.431	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0326	0.431	0.5
Echinococcus granulosus	tyrosine protein kinase Btk29A	0.0581	0.9952	0.995
Trichomonas vaginalis	TKL family protein kinase	0.0326	0.431	0.5
Echinococcus granulosus	tyrosine protein kinase Fes:Fps	0.0326	0.431	0.4053
Brugia malayi	hypothetical protein	0.0255	0.276	0.2234
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0326	0.431	0.4012
Entamoeba histolytica	protein kinase, putative	0.0326	0.431	0.4012
Echinococcus multilocularis	tyrosine protein kinase lyn tyrosine protein kinase blk	0.0581	0.9952	1
Schistosoma mansoni	tyrosine kinase	0.0326	0.431	0.3227
Entamoeba histolytica	protein kinase domain containing protein	0.0326	0.431	0.4012
Onchocerca volvulus		0.0326	0.431	0.4331
Brugia malayi	RhoGAP domain containing protein	0.0327	0.4334	0.3933
Entamoeba histolytica	hypothetical protein	0.0326	0.431	0.4012
Loa Loa (eye worm)	hypothetical protein	0.0326	0.431	0.4331
Echinococcus multilocularis	tyrosine protein kinase	0.0326	0.431	0.3081
Echinococcus granulosus	tyrosine protein phosphatase non receptor type	0.0255	0.276	0.2432
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0326	0.431	0.3908
Trichomonas vaginalis	TKL family protein kinase	0.0326	0.431	0.5
Loa Loa (eye worm)	TK/ABL protein kinase	0.0581	0.9952	1
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0581	0.9952	0.995
Trichomonas vaginalis	TKL family protein kinase	0.0326	0.431	0.5
Echinococcus granulosus	growth factor receptor bound protein 2	0.0255	0.276	0.2432
Trichomonas vaginalis	TKL family protein kinase	0.0326	0.431	0.5
Loa Loa (eye worm)	TK/Met protein kinase	0.0326	0.431	0.4331
Brugia malayi	Protein kinase domain containing protein	0.0326	0.431	0.3908
Loa Loa (eye worm)	TKL/MLK/TAK1 protein kinase	0.0326	0.431	0.4331
Echinococcus granulosus	tyrosine protein phosphatase non receptor type	0.0255	0.276	0.2432
Schistosoma mansoni	protein kinase	0.0328	0.4358	0.3285
Entamoeba histolytica	leucine-rich repeat domain-containing protein	0.0326	0.431	0.4012
Loa Loa (eye worm)	hypothetical protein	0.0581	0.9952	1
Brugia malayi	Adenylate and Guanylate cyclase catalytic domain containing protein	0.0326	0.431	0.3908
Entamoeba histolytica	protein kinase domain containing protein	0.0326	0.431	0.4012
Entamoeba histolytica	tyrosine kinase, putative	0.0326	0.431	0.4012
Entamoeba histolytica	serine/threonine kinase, putative	0.0326	0.431	0.4012
Echinococcus granulosus	tyrosine protein kinase Blk	0.0581	0.9952	0.995
Entamoeba histolytica	serine/threonine kinase, putative	0.0326	0.431	0.4012
Trichomonas vaginalis	STE family protein kinase	0.0326	0.431	0.5
Echinococcus multilocularis	atrial natriuretic peptide receptor 1	0.0326	0.431	0.3081
Schistosoma mansoni	tyrosine kinase	0.0326	0.431	0.3227
Schistosoma mansoni	proto-oncogene tyrosine-protein kinase abl1	0.0255	0.276	0.1366
Entamoeba histolytica	protein kinase domain containing protein	0.0326	0.431	0.4012
Entamoeba histolytica	protein kinase domain containing protein	0.0326	0.431	0.4012
Loa Loa (eye worm)	hypothetical protein	0.0326	0.431	0.4331
Entamoeba histolytica	protein kinase, putative	0.0326	0.431	0.4012
Brugia malayi	Protein kinase domain containing protein	0.0326	0.431	0.3908
Schistosoma mansoni	serine/threonine protein kinase	0.0283	0.3372	0.2101
Entamoeba histolytica	protein kinase, putative	0.0326	0.431	0.4012
Echinococcus granulosus	activated cdc42 kinase 1	0.0326	0.431	0.4053
Echinococcus multilocularis	tyrosine protein kinase ABL1	0.0581	0.9952	1
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0326	0.431	0.4012
Echinococcus granulosus	insulin receptor	0.0326	0.431	0.4053
Brugia malayi	C-terminal src kinase protein 1	0.0326	0.431	0.3908
Brugia malayi	hypothetical protein	0.0326	0.431	0.3908
Entamoeba histolytica	tyrosine kinase, putative	0.0326	0.431	0.4012
Entamoeba histolytica	hypothetical protein, conserved	0.0326	0.431	0.4012
Loa Loa (eye worm)	hypothetical protein	0.0255	0.276	0.2773
Loa Loa (eye worm)	CAMK/PKD protein kinase	0.0204	0.1622	0.163
Loa Loa (eye worm)	TK/DDR protein kinase	0.0326	0.431	0.4331
Schistosoma mansoni	protein kinase	0.0326	0.431	0.3227
Schistosoma mansoni	tyrosine kinase	0.0326	0.431	0.3227
Schistosoma mansoni	growth factor receptor-bound protein	0.0255	0.276	0.1366
Entamoeba histolytica	protein kinase domain containing protein	0.0326	0.431	0.4012
Trichomonas vaginalis	conserved hypothetical protein	0.0326	0.431	0.5
Echinococcus granulosus	tyrosine protein kinase Btk29A	0.0326	0.431	0.4053
Entamoeba histolytica	protein kinase, putative	0.0326	0.431	0.4012
Echinococcus granulosus	guanine nucleotide exchange factor VAV2	0.0327	0.4334	0.4077
Echinococcus granulosus	Protein kinase C brain isozyme	0.0283	0.3372	0.3072
Schistosoma mansoni	hypothetical protein	0.0255	0.276	0.1366
Loa Loa (eye worm)	TK/FER protein kinase	0.0326	0.431	0.4331
Entamoeba histolytica	hypothetical protein	0.0326	0.431	0.4012
Trichomonas vaginalis	TKL family protein kinase	0.0326	0.431	0.5
Loa Loa (eye worm)	hypothetical protein	0.0255	0.276	0.2773
Loa Loa (eye worm)	TK/FER protein kinase	0.0326	0.431	0.4331
Schistosoma mansoni	shc transforming protein	0.0255	0.276	0.1366
Trichomonas vaginalis	TKL family protein kinase	0.0326	0.431	0.5
Echinococcus multilocularis	N chimaerin	0.0327	0.4334	0.311
Echinococcus granulosus	receptor type guanylyl cyclase	0.0326	0.431	0.4053
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0326	0.431	0.4331
Trichomonas vaginalis	conserved hypothetical protein	0.0326	0.431	0.5
Echinococcus multilocularis	SH2 domain containing adapter protein F	0.0255	0.276	0.118
Schistosoma mansoni	tyrosine-protein kinase fps85d	0.0326	0.431	0.3227
Trichomonas vaginalis	TKL family protein kinase	0.0326	0.431	0.5
Echinococcus multilocularis	signal transduction protein lnk realted	0.0255	0.276	0.118
Loa Loa (eye worm)	cytokine inducible SH2-containing protein 5	0.0255	0.276	0.2773
Echinococcus granulosus	c src tyrosine kinase	0.0581	0.9952	0.995
Echinococcus multilocularis	tyrosine protein kinase transmembrane receptor	0.0326	0.431	0.3081
Trichomonas vaginalis	TKL family protein kinase	0.0326	0.431	0.5
Loa Loa (eye worm)	STAT protein	0.0255	0.276	0.2773
Trichomonas vaginalis	TKL family protein kinase	0.0326	0.431	0.5
Brugia malayi	Protein kinase domain containing protein	0.0326	0.431	0.3908
Trichomonas vaginalis	TKL family protein kinase	0.0326	0.431	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0326	0.431	0.5
Loa Loa (eye worm)	hypothetical protein	0.0296	0.3652	0.3669
Trichomonas vaginalis	TKL family protein kinase	0.0326	0.431	0.5
Onchocerca volvulus	Atrial natriuretic peptide receptor 3 homolog	0.0326	0.431	0.4331
Echinococcus granulosus	tyrosine kinase	0.0326	0.431	0.4053
Onchocerca volvulus		0.0581	0.9952	1
Schistosoma mansoni	protein kinase	0.0326	0.431	0.3227
Schistosoma mansoni	hypothetical protein	0.0255	0.276	0.1366
Leishmania major	protein kinase, putative	0.0328	0.4358	1
Schistosoma mansoni	serine/threonine protein kinase	0.0283	0.3372	0.2101
Brugia malayi	Protein kinase domain containing protein	0.0326	0.431	0.3908
Brugia malayi	C1-like domain containing protein	0.0204	0.1622	0.1005
Echinococcus multilocularis	natriuretic peptide receptor 1	0.0326	0.431	0.3081
Echinococcus multilocularis	SH2 motif	0.0255	0.276	0.118
Trichomonas vaginalis	TKL family protein kinase	0.0326	0.431	0.5
Loa Loa (eye worm)	hypothetical protein	0.0255	0.276	0.2773
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.0326	0.431	0.3081
Trichomonas vaginalis	TKL family protein kinase	0.0326	0.431	0.5
Trichomonas vaginalis	CAMK family protein kinase	0.0326	0.431	0.5
Loa Loa (eye worm)	sex muscle abnormal protein 5	0.0255	0.276	0.2773
Entamoeba histolytica	protein kinase, putative	0.0326	0.431	0.4012
Entamoeba histolytica	hypothetical protein	0.0326	0.431	0.4012
Brugia malayi	Protein kinase domain containing protein	0.0326	0.431	0.3908
Echinococcus multilocularis		0.0255	0.276	0.118
Loa Loa (eye worm)	hypothetical protein	0.0326	0.431	0.4331
Loa Loa (eye worm)	variant SH3 domain-containing protein	0.0255	0.276	0.2773
Loa Loa (eye worm)	TK/ACK protein kinase	0.0326	0.431	0.4331
Schistosoma mansoni	tyrosine kinase	0.0326	0.431	0.3227
Giardia lamblia	Kinase, NEK	0.0326	0.431	0.5
Echinococcus multilocularis	insulin growth factor 1 receptor beta	0.0326	0.431	0.3081
Trichomonas vaginalis	TKL family protein kinase	0.0326	0.431	0.5
Echinococcus multilocularis	NCK adaptor protein	0.0255	0.276	0.118
Schistosoma mansoni	protein kinase	0.0326	0.431	0.3227
Brugia malayi	SH2 domain containing protein	0.0255	0.276	0.2234
Loa Loa (eye worm)	hypothetical protein	0.0326	0.431	0.4331
Brugia malayi	Protein kinase domain containing protein	0.0326	0.431	0.3908
Trichomonas vaginalis	TKL family protein kinase	0.0326	0.431	0.5
Echinococcus multilocularis	tensin	0.0255	0.276	0.118
Schistosoma mansoni	tyrosine kinase	0.0326	0.431	0.3227
Entamoeba histolytica	protein kinase with ankyrin repeats, putative	0.0326	0.431	0.4012
Brugia malayi	SRC-1	0.0581	0.9952	1
Brugia malayi	bone morphogenetic protein type 1 receptor	0.0326	0.431	0.3908
Entamoeba histolytica	protein kinase domain containing protein	0.0326	0.431	0.4012
Entamoeba histolytica	receptor protein kinase, putative	0.0326	0.431	0.4012
Entamoeba histolytica	protein kinase, putative	0.0326	0.431	0.4012
Echinococcus granulosus	tyrosine protein kinase Src42A	0.0255	0.276	0.2432
Trichomonas vaginalis	TKL family protein kinase	0.0326	0.431	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0326	0.431	0.5
Brugia malayi	SH2 domain containing protein	0.0255	0.276	0.2234
Entamoeba histolytica	protein kinase, putative	0.0326	0.431	0.4012
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0326	0.431	0.4012
Schistosoma mansoni	GTPase activating protein	0.0255	0.276	0.1366
Schistosoma mansoni	tyrosine kinase	0.0581	0.9952	1
Trichomonas vaginalis	TKL family protein kinase	0.0326	0.431	0.5
Loa Loa (eye worm)	RhoGAP domain-containing protein	0.0327	0.4334	0.4355
Echinococcus multilocularis	serine:threonine protein kinase N2	0.0226	0.2116	0.039
Trichomonas vaginalis	TKL family protein kinase	0.0326	0.431	0.5
Schistosoma mansoni	tyrosine kinase	0.0326	0.431	0.3227
Schistosoma mansoni	hypothetical protein	0.0326	0.431	0.3227
Brugia malayi	Tyrosine-protein kinase F09A5.2 in chromosome X, putative	0.0326	0.431	0.3908
Schistosoma mansoni	tyrosine kinase	0.0326	0.431	0.3227
Loa Loa (eye worm)	hypothetical protein	0.0255	0.276	0.2773
Echinococcus granulosus	N chimaerin	0.0327	0.4334	0.4077
Schistosoma mansoni	protein tyrosine kinase	0.0326	0.431	0.3227
Loa Loa (eye worm)	SH2 domain-containing protein	0.0255	0.276	0.2773
Loa Loa (eye worm)	TKL/RAF/RAF protein kinase	0.0326	0.431	0.4331
Schistosoma mansoni	serine/threonine protein kinase	0.0326	0.431	0.3227
Schistosoma mansoni	serine/threonine RGC	0.0326	0.431	0.3227
Loa Loa (eye worm)	AGC/PKC/IOTA protein kinase	0.0168	0.0835	0.0839
Echinococcus multilocularis	suppressor of cytokine signaling 6	0.0255	0.276	0.118
Echinococcus granulosus	kinase suppressor of Ras 1	0.0326	0.431	0.4053
Loa Loa (eye worm)	TK/FER protein kinase	0.0326	0.431	0.4331
Echinococcus multilocularis	SH2 domain containing protein 7	0.0255	0.276	0.118
Entamoeba histolytica	tyrosine kinase, putative	0.0326	0.431	0.4012
Echinococcus multilocularis	fibroblast growth factor receptor 4	0.0326	0.431	0.3081
Onchocerca volvulus		0.0581	0.9952	1
Schistosoma mansoni	tyrosine kinase	0.0326	0.431	0.3227
Plasmodium vivax	protein kinase, putative	0.0326	0.431	0.5
Echinococcus multilocularis	tyrosine protein kinase csk	0.0326	0.431	0.3081
Entamoeba histolytica	protein kinase domain containing protein	0.0326	0.431	0.4012
Toxoplasma gondii	calcium dependent protein kinase CDPK8	0.0328	0.4358	1
Trichomonas vaginalis	TKL family protein kinase	0.0326	0.431	0.5
Echinococcus multilocularis	protein KINase family member (kin 25)	0.0326	0.431	0.3081
Echinococcus multilocularis	receptor type guanylyl cyclase	0.0326	0.431	0.3081
Trichomonas vaginalis	TKL family protein kinase	0.0326	0.431	0.5
Echinococcus multilocularis	growth factor receptor bound protein 2	0.0255	0.276	0.118
Loa Loa (eye worm)	TK/FER protein kinase	0.0581	0.9952	1
Schistosoma mansoni	chimerin-related rho-gtpase-activating protein	0.0327	0.4334	0.3255
Trichomonas vaginalis	TKL family protein kinase	0.0326	0.431	0.5
Loa Loa (eye worm)	TK/ALK protein kinase	0.0326	0.431	0.4331
Loa Loa (eye worm)	hypothetical protein	0.0198	0.1492	0.1499
Echinococcus multilocularis	raf serine:threonine protein kinase	0.0397	0.5884	0.5011
Schistosoma mansoni	protein tyrosine phosphatase n11 (shp2)	0.0255	0.276	0.1366
Entamoeba histolytica	tyrosine kinase, putative	0.0326	0.431	0.4012
Trichomonas vaginalis	TKL family protein kinase	0.0326	0.431	0.5
Echinococcus multilocularis	tyrosine protein kinase Src64B	0.0581	0.9952	1
Echinococcus granulosus	tyrosine protein kinase Fps85D	0.0581	0.9952	0.995
Brugia malayi	Probable tyrosine-protein kinase kin-31	0.0326	0.431	0.3908
Trichomonas vaginalis	conserved hypothetical protein	0.0326	0.431	0.5
Loa Loa (eye worm)	hypothetical protein	0.0326	0.431	0.4331
Loa Loa (eye worm)	hypothetical protein	0.0326	0.431	0.4331
Brugia malayi	Protein kinase domain containing protein	0.0326	0.431	0.3908
Trichomonas vaginalis	TKL family protein kinase	0.0326	0.431	0.5
Entamoeba histolytica	protein kinase domain containing protein	0.0326	0.431	0.4012
Entamoeba histolytica	tyrosine kinase, putative	0.0326	0.431	0.4012
Entamoeba histolytica	hypothetical protein	0.0326	0.431	0.4012
Brugia malayi	Protein kinase domain containing protein	0.0326	0.431	0.3908
Entamoeba histolytica	tyrosin kinase, putative	0.0326	0.431	0.4012
Echinococcus multilocularis	tyrosine protein kinase csk	0.0326	0.431	0.3081
Schistosoma mansoni	tyrosine kinase	0.0326	0.431	0.3227
Loa Loa (eye worm)	hypothetical protein	0.0255	0.276	0.2773
Plasmodium vivax	tyrosine kinase-like protein, putative	0.0326	0.431	0.5
Entamoeba histolytica	tyrosine kinase, putative	0.0326	0.431	0.4012
Loa Loa (eye worm)	TK protein kinase	0.0326	0.431	0.4331
Schistosoma mansoni	tyrosine protein kinase fes (fps) (ptk group IV)	0.0326	0.431	0.3227
Echinococcus granulosus	fibroblast growth factor receptor 4	0.0326	0.431	0.4053
Echinococcus multilocularis	tyrosine protein phosphatase non receptor type	0.0255	0.276	0.118
Trichomonas vaginalis	TKL family protein kinase	0.0326	0.431	0.5
Brugia malayi	Protein kinase domain containing protein	0.0326	0.431	0.3908
Entamoeba histolytica	hypothetical protein	0.0326	0.431	0.4012
Brugia malayi	hypothetical protein	0.0581	0.9952	1
Trichomonas vaginalis	TKL family protein kinase	0.0326	0.431	0.5
Entamoeba histolytica	serine/threonine kinase, putative	0.0326	0.431	0.4012
Brugia malayi	Sex muscle abnormal protein 5	0.0255	0.276	0.2234
Loa Loa (eye worm)	TK/FER protein kinase	0.0326	0.431	0.4331
Echinococcus multilocularis	heat shock protein 70	0.0326	0.431	0.3081
Brugia malayi	Protein kinase domain containing protein	0.0581	0.9952	1
Echinococcus multilocularis	tyrosine protein kinase csk	0.0326	0.431	0.3081
Trichomonas vaginalis	TKL family protein kinase	0.0326	0.431	0.5
Echinococcus granulosus	activated cdc42 kinase 1	0.0326	0.431	0.4053
Echinococcus multilocularis	phosphatidylinositol 3 kinase regulatory subunit	0.0255	0.276	0.118
Loa Loa (eye worm)	hypothetical protein	0.0374	0.5383	0.5409
Loa Loa (eye worm)	hypothetical protein	0.0255	0.276	0.2773
Onchocerca volvulus	Tyrosine kinase receptor Cad96Ca homolog	0.0326	0.431	0.4331
Entamoeba histolytica	protein kinase, putative	0.0326	0.431	0.4012
Loa Loa (eye worm)	TK protein kinase	0.0326	0.431	0.4331
Echinococcus granulosus	protein kinase	0.0326	0.431	0.4053
Schistosoma mansoni	suppressor of cytokine signaling	0.0255	0.276	0.1366
Echinococcus multilocularis	tyrosine protein kinase Blk	0.0581	0.9952	1
Loa Loa (eye worm)	hypothetical protein	0.0255	0.276	0.2773
Echinococcus multilocularis	protein kinase	0.0326	0.431	0.3081
Loa Loa (eye worm)	hypothetical protein	0.0326	0.431	0.4331
Entamoeba histolytica	tyrosine- protein kinase 2, putative	0.0326	0.431	0.4012
Schistosoma mansoni	atypical protein kinase C	0.0244	0.2518	0.1075
Echinococcus multilocularis	tyrosine protein kinase transmembrane receptor	0.0326	0.431	0.3081
Onchocerca volvulus		0.0581	0.9952	1
Entamoeba histolytica	hypothetical protein	0.0326	0.431	0.4012
Loa Loa (eye worm)	TK/EGFR protein kinase	0.0326	0.431	0.4331
Trichomonas vaginalis	AGC family protein kinase	0.0326	0.431	0.5
Echinococcus granulosus	protein kinase c epsilon type	0.0304	0.3838	0.3559
Trichomonas vaginalis	TKL family protein kinase	0.0326	0.431	0.5
Loa Loa (eye worm)	TK/KIN16 protein kinase	0.0326	0.431	0.4331
Entamoeba histolytica	SH2-protein kinase domain containing protein	0.0581	0.9952	1
Entamoeba histolytica	tyrosine kinase, putative	0.0326	0.431	0.4012
Echinococcus multilocularis	tyrosine protein kinase Fes:Fps	0.0326	0.431	0.3081
Schistosoma mansoni	SH2A	0.0255	0.276	0.1366
Trichomonas vaginalis	TKL family protein kinase	0.0326	0.431	0.5
Brugia malayi	tRNA modification GTPase TrmE family protein	0.0255	0.276	0.2234
Brugia malayi	SH2 domain containing protein	0.0255	0.276	0.2234
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0326	0.431	0.4331
Schistosoma mansoni	tyrosine kinase	0.0326	0.431	0.3227
Brugia malayi	Protein kinase domain containing protein	0.0326	0.431	0.3908
Trichomonas vaginalis	TKL family protein kinase	0.0326	0.431	0.5
Schistosoma mansoni	protein kinase	0.0326	0.431	0.3227
Brugia malayi	Protein kinase domain containing protein	0.0326	0.431	0.3908
Brugia malayi	Furin-like cysteine rich region family protein	0.0326	0.431	0.3908
Loa Loa (eye worm)	hypothetical protein	0.0296	0.3652	0.3669
Entamoeba histolytica	tyrosine kinase, putative	0.0326	0.431	0.4012
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0581	0.9952	1
Schistosoma mansoni	tensin-related	0.0255	0.276	0.1366
Trichomonas vaginalis	conserved hypothetical protein	0.0326	0.431	0.5
Schistosoma mansoni	tyrosine kinase	0.0326	0.431	0.3227
Schistosoma mansoni	ephrin receptor	0.0326	0.431	0.3227
Schistosoma mansoni	src-type protein tyrosine kinase-related	0.0326	0.431	0.3227
Loa Loa (eye worm)	TK/FER protein kinase	0.0581	0.9952	1
Echinococcus granulosus	expressed conserved protein	0.0255	0.276	0.2432
Brugia malayi	STAT protein, DNA binding domain containing protein	0.0255	0.276	0.2234
Echinococcus multilocularis	protein kinase	0.0326	0.431	0.3081
Onchocerca volvulus		0.0326	0.431	0.4331
Entamoeba histolytica	protein kinase domain containing protein	0.0326	0.431	0.4012
Loa Loa (eye worm)	hypothetical protein	0.0326	0.431	0.4331
Schistosoma mansoni	tyrosine kinase	0.0326	0.431	0.3227
Echinococcus multilocularis	SH2 motif	0.0255	0.276	0.118
Loa Loa (eye worm)	TK/KIN6 protein kinase	0.0326	0.431	0.4331
Schistosoma mansoni	tyrosine-protein kinase fps85d	0.0326	0.431	0.3227
Echinococcus granulosus	tyrosine protein kinase transmembrane receptor	0.0326	0.431	0.4053
Echinococcus multilocularis	suppressor of cytokine signaling 7	0.0255	0.276	0.118
Onchocerca volvulus		0.0326	0.431	0.4331
Echinococcus granulosus	tensin	0.0255	0.276	0.2432
Entamoeba histolytica	hypothetical protein	0.0326	0.431	0.4012
Entamoeba histolytica	hypothetical protein	0.0326	0.431	0.4012
Entamoeba histolytica	protein kinase domain containing protein	0.0326	0.431	0.4012
Trichomonas vaginalis	TKL family protein kinase	0.0326	0.431	0.5
Schistosoma mansoni	signal transduction protein lnk-related	0.0255	0.276	0.1366
Echinococcus multilocularis	protein tyrosine kinase	0.0326	0.431	0.3081
Onchocerca volvulus		0.0202	0.1574	0.1581
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0581	0.9952	1
Echinococcus granulosus	SHC transforming protein 3	0.0255	0.276	0.2432

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL2369659

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 1742512