Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | zinc finger protein | 0.0729 | 0.9113 | 0.9097 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.0301 | 0.0125 |
Trichomonas vaginalis | transmembrane protein nessy, putative | 0.0069 | 0.0593 | 1 |
Schistosoma mansoni | membrane-bound acyltransferase/hhat | 0.0069 | 0.0593 | 0.0423 |
Loa Loa (eye worm) | MBOAT family protein | 0.0069 | 0.0593 | 0.0593 |
Trypanosoma brucei | glycerol uptake protein, putative | 0.0069 | 0.0593 | 1 |
Leishmania major | glycerol uptake protein, putative | 0.0069 | 0.0593 | 1 |
Trypanosoma cruzi | GUP1, putative | 0.0069 | 0.0593 | 1 |
Toxoplasma gondii | acyl-CoA:diacylglycerol acyltransferase 1-related enzyme | 0.0069 | 0.0593 | 0.5 |
Treponema pallidum | alginate O-acetylation protein (algI) | 0.0069 | 0.0593 | 0.5 |
Plasmodium falciparum | diacylglycerol O-acyltransferase | 0.0069 | 0.0593 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0069 | 0.0593 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0069 | 0.0593 | 0.0423 |
Echinococcus granulosus | sterol O acyltransferase 1 | 0.0069 | 0.0593 | 0.0423 |
Trypanosoma cruzi | glycerol uptake protein, putative | 0.0069 | 0.0593 | 1 |
Echinococcus granulosus | protein cysteine N palmitoyltransferase | 0.0798 | 1 | 1 |
Loa Loa (eye worm) | hhat protein | 0.0069 | 0.0593 | 0.0593 |
Leishmania major | glycerol uptake protein, putative | 0.0069 | 0.0593 | 1 |
Echinococcus granulosus | diacylglycerol O acyltransferase 1 | 0.0069 | 0.0593 | 0.0423 |
Loa Loa (eye worm) | MBOAT family protein | 0.0069 | 0.0593 | 0.0593 |
Toxoplasma gondii | acyl-CoA:cholesterol acyltransferase alpha ACAT1-alpha | 0.0069 | 0.0593 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.0593 | 0.0593 |
Echinococcus granulosus | Membrane bound O acyl transferase MBOAT | 0.0069 | 0.0593 | 0.0423 |
Schistosoma mansoni | o-acyltransferase (membrane bound) domain containing protein | 0.0069 | 0.0593 | 0.0423 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0301 | 0.0125 |
Brugia malayi | Hhat protein | 0.0069 | 0.0593 | 0.0593 |
Loa Loa (eye worm) | hhat protein | 0.0069 | 0.0593 | 0.0593 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.0301 | 0.0125 |
Echinococcus multilocularis | membrane bound acyltransferase:hhat | 0.0069 | 0.0593 | 0.0423 |
Schistosoma mansoni | o-acyltransferase (membrane bound) domain containing protein | 0.0069 | 0.0593 | 0.0423 |
Loa Loa (eye worm) | diacylglycerol acyltransferase | 0.0069 | 0.0593 | 0.0593 |
Trypanosoma cruzi | GUP1, putative | 0.0069 | 0.0593 | 1 |
Plasmodium vivax | diacylglycerol O-acyltransferase, putative | 0.0069 | 0.0593 | 0.5 |
Schistosoma mansoni | sterol O-acyltransferase 1 | 0.0069 | 0.0593 | 0.0423 |
Echinococcus multilocularis | sterol O acyltransferase 1 | 0.0069 | 0.0593 | 0.0423 |
Echinococcus granulosus | lysophospholipid acyltransferase 7 | 0.0069 | 0.0593 | 0.0423 |
Trypanosoma brucei | glycerol uptake protein, putative | 0.0069 | 0.0593 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0069 | 0.0593 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0069 | 0.0593 | 1 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0046 | 0.0301 | 0.0301 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0301 | 0.0125 |
Echinococcus multilocularis | o acyltransferase (membrane bound) domain | 0.0069 | 0.0593 | 0.0423 |
Leishmania major | glycerol uptake protein, putative | 0.0069 | 0.0593 | 1 |
Echinococcus multilocularis | protein cysteine N palmitoyltransferase | 0.0798 | 1 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0069 | 0.0593 | 1 |
Loa Loa (eye worm) | MBOAT family protein | 0.0798 | 1 | 1 |
Trypanosoma cruzi | glycerol uptake protein, putative | 0.0069 | 0.0593 | 1 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.03 | 0.3577 | 0.3461 |
Echinococcus granulosus | membrane bound acyltransferase:hhat | 0.0069 | 0.0593 | 0.0423 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0069 | 0.0593 | 1 |
Entamoeba histolytica | membrane-bound O-acyltransferase (MBOAT ) family protein | 0.0069 | 0.0593 | 1 |
Brugia malayi | MBOAT family protein | 0.0069 | 0.0593 | 0.0593 |
Echinococcus multilocularis | Membrane bound O acyl transferase, MBOAT | 0.0069 | 0.0593 | 0.0423 |
Entamoeba histolytica | membrane-bound O-acyltransferase (MBOAT ) family protein | 0.0069 | 0.0593 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0301 | 0.0125 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0178 | 0.0178 |
Echinococcus multilocularis | zinc finger protein | 0.0729 | 0.9113 | 0.9097 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.0593 | 0.0593 |
Onchocerca volvulus | 0.0069 | 0.0593 | 0.5 | |
Loa Loa (eye worm) | membrane bound O-acyltransferase domain containing 1 | 0.0069 | 0.0593 | 0.0593 |
Leishmania major | glycerol uptake protein, putative | 0.0069 | 0.0593 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0046 | 0.0301 | 0.0301 |
Echinococcus multilocularis | lysophospholipid acyltransferase 7 | 0.0069 | 0.0593 | 0.0423 |
Leishmania major | glycerol uptake protein, putative | 0.0069 | 0.0593 | 1 |
Schistosoma mansoni | leukocyte receptor cluster (lrc) member 4 protein | 0.0069 | 0.0593 | 0.0423 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.0593 | 0.0593 |
Toxoplasma gondii | hypothetical protein | 0.0069 | 0.0593 | 0.5 |
Echinococcus multilocularis | o acyltransferase (membrane bound) domain | 0.0069 | 0.0593 | 0.0423 |
Trichomonas vaginalis | porcupine, putative | 0.0069 | 0.0593 | 1 |
Giardia lamblia | Ubiquitin carboxyl-terminal hydrolase 4 | 0.0037 | 0.0178 | 0.5 |
Schistosoma mansoni | zinc finger protein | 0.0798 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.0593 | 0.0593 |
Echinococcus granulosus | o acyltransferase membrane bound domain | 0.0069 | 0.0593 | 0.0423 |
Schistosoma mansoni | o-acyltransferase (membrane bound) domain containing protein | 0.0069 | 0.0593 | 0.0423 |
Brugia malayi | Ubiquitin carboxyl-terminal hydrolase family protein | 0.0037 | 0.0178 | 0.0178 |
Schistosoma mansoni | diacylglycerol O-acyltransferase 1 | 0.0069 | 0.0593 | 0.0423 |
Brugia malayi | MBOAT family protein | 0.0069 | 0.0593 | 0.0593 |
Echinococcus multilocularis | o acyltransferase (membrane bound) domain | 0.0069 | 0.0593 | 0.0423 |
Echinococcus granulosus | o acyltransferase membrane bound domain | 0.0069 | 0.0593 | 0.0423 |
Entamoeba histolytica | membrane-bound O-acyltransferase (MBOAT ) family protein | 0.0069 | 0.0593 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.0301 | 0.0125 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.03 | 0.3577 | 0.3461 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0069 | 0.0593 | 1 |
Brugia malayi | diacylglycerol acyltransferase | 0.0069 | 0.0593 | 0.0593 |
Entamoeba histolytica | vacuolar protein sorting 26 | 0.0069 | 0.0593 | 1 |
Brugia malayi | MBOAT family protein | 0.0069 | 0.0593 | 0.0593 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.0301 | 0.0125 |
Echinococcus multilocularis | diacylglycerol O acyltransferase 1 | 0.0069 | 0.0593 | 0.0423 |
Trypanosoma cruzi | glycerol uptake protein, putative | 0.0069 | 0.0593 | 1 |
Brugia malayi | MBOAT family protein | 0.0069 | 0.0593 | 0.0593 |
Echinococcus granulosus | o acyltransferase membrane bound domain | 0.0069 | 0.0593 | 0.0423 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.