Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Toxoplasma gondii | bromodomain-containing protein | 0.0037 | 0.2059 | 1 |
Schistosoma mansoni | bromodomain-containing protein 3 brd3 | 0.008 | 0.6639 | 0.7603 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0054 | 0.3903 | 0.4028 |
Brugia malayi | PHD-finger family protein | 0.0026 | 0.0921 | 0.0994 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0026 | 0.0921 | 0.1387 |
Onchocerca volvulus | 0.0037 | 0.2059 | 1 | |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.0026 | 0.0921 | 0.0921 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.008 | 0.6639 | 1 |
Echinococcus multilocularis | peregrin | 0.0112 | 1 | 1 |
Brugia malayi | Bromodomain containing protein | 0.008 | 0.6639 | 0.7166 |
Plasmodium vivax | hypothetical protein, conserved | 0.0026 | 0.0921 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0051 | 0.3507 | 0.3163 |
Trichomonas vaginalis | bromodomain containing protein, putative | 0.0051 | 0.3507 | 0.3163 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0921 | 0.1387 |
Echinococcus multilocularis | Bromodomain containing protein | 0.0037 | 0.2059 | 0.2059 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0037 | 0.2059 | 0.3101 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0051 | 0.3507 | 0.3163 |
Entamoeba histolytica | bromodomain-containing protein | 0.0037 | 0.2059 | 0.5 |
Echinococcus granulosus | bromodomain containing 2 | 0.008 | 0.6639 | 0.6639 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0051 | 0.3507 | 0.3163 |
Entamoeba histolytica | bromodomain-containing protein | 0.0037 | 0.2059 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.6639 | 1 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.0026 | 0.0921 | 0.0921 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.008 | 0.6639 | 1 |
Brugia malayi | Bromodomain containing protein | 0.0105 | 0.9264 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.3903 | 0.588 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0043 | 0.2684 | 0.1365 |
Brugia malayi | Bromodomain containing protein | 0.008 | 0.6639 | 0.7166 |
Entamoeba histolytica | bromodomain-containing protein | 0.0037 | 0.2059 | 0.5 |
Brugia malayi | hypothetical protein | 0.0029 | 0.1235 | 0.1333 |
Giardia lamblia | Kinase, putative | 0.0037 | 0.2059 | 1 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.0097 | 0.8441 | 1 |
Plasmodium falciparum | phd finger protein, putative | 0.0026 | 0.0921 | 0.5 |
Echinococcus multilocularis | bromodomain containing 2 | 0.008 | 0.6639 | 0.6639 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0051 | 0.3507 | 0.3163 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.