Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.0007 | 0.0003 | 0.0006 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.001 | 0.0007 | 0.0016 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.3433 | 0.4043 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.001 | 0.0007 | 0.0016 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.001 | 0.0007 | 0.0016 |
Brugia malayi | Carbonic anhydrase like protein 2 precursor | 0.14 | 0.1646 | 0.4069 |
Toxoplasma gondii | exonuclease III APE | 0.0018 | 0.0017 | 0.0018 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.001 | 0.0007 | 0.0016 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0018 | 0.0017 | 0.0033 |
Schistosoma mansoni | nuclear hormone receptor | 0.001 | 0.0007 | 0.0007 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.001 | 0.0007 | 0.0016 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0014 | 0.0032 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.001 | 0.0007 | 0.0016 |
Brugia malayi | Carbonic anhydrase like protein 2 precursor | 0.14 | 0.1646 | 0.4069 |
Leishmania major | tyrosyl-DNA phosphodiesterase 1 | 0.0065 | 0.0072 | 0.0058 |
Schistosoma mansoni | ap endonuclease | 0.0018 | 0.0017 | 0.0017 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0002 | 0.0002 |
Schistosoma mansoni | thyroid hormone receptor | 0.001 | 0.0007 | 0.0007 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.001 | 0.0007 | 0.0016 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.14 | 0.1646 | 0.4069 |
Onchocerca volvulus | 0.0028 | 0.0028 | 1 | |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.001 | 0.0007 | 0.0016 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0006 | 0.0011 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0005 | 0.0001 | 0.0001 |
Brugia malayi | Putative carbonic anhydrase 5 precursor | 0.3433 | 0.4043 | 1 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.001 | 0.0007 | 0.0016 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0014 | 0.0032 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.001 | 0.0007 | 0.0016 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0007 | 0.0016 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.003 | 0.003 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.001 | 0.0007 | 0.0007 |
Loa Loa (eye worm) | histone methyltransferase | 0.0009 | 0.0006 | 0.0011 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0002 | 0.0002 |
Echinococcus granulosus | FTZ F1 alpha | 0.001 | 0.0007 | 0.0016 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.0065 | 0.0072 | 0.0175 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.001 | 0.0007 | 0.0016 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.001 | 0.0007 | 0.0016 |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.0007 | 0.0003 | 0.0006 |
Brugia malayi | hypothetical protein | 0.0005 | 0.0002 | 0.0002 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0009 | 0.0005 | 0.0011 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.001 | 0.0007 | 0.0016 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0005 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0018 | 0.0017 | 0.004 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0018 | 0.0017 | 0.004 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.3433 | 0.4043 | 1 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0018 | 0.0017 | 0.004 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.006 | 0.0066 | 0.0066 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0007 | 0.0016 |
Toxoplasma gondii | hypothetical protein | 0.14 | 0.1646 | 1 |
Brugia malayi | nuclear receptor RXR | 0.0005 | 0.0002 | 0.0002 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0018 | 0.0017 | 0.0005 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.3433 | 0.4043 | 1 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.14 | 0.1646 | 0.4069 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0018 | 0.0017 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.001 | 0.0007 | 0.0016 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.001 | 0.0007 | 0.0016 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.0065 | 0.0072 | 0.0175 |
Brugia malayi | ecdysteroid receptor | 0.001 | 0.0007 | 0.0016 |
Loa Loa (eye worm) | carbonic anhydrase 3 | 0.3433 | 0.4043 | 1 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0005 | 0.0001 | 0.0001 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0016 | 0.0014 | 0.0032 |
Schistosoma mansoni | carbonic anhydrase | 0.14 | 0.1646 | 0.1646 |
Schistosoma mansoni | nuclear hormone receptor | 0.0005 | 0.0001 | 0.0001 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0007 | 0.0016 |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.0065 | 0.0072 | 0.0175 |
Onchocerca volvulus | Bile acid receptor homolog | 0.001 | 0.0007 | 0.2307 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.001 | 0.0007 | 0.0016 |
Echinococcus multilocularis | transcription factor Dp 1 | 0.0037 | 0.0039 | 0.0095 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0051 | 0.0055 | 0.0134 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0007 | 0.0016 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.001 | 0.0007 | 0.0016 |
Echinococcus multilocularis | cpg binding protein | 0.003 | 0.003 | 0.0073 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0007 | 0.0003 | 0.0006 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0016 | 0.0014 | 0.0032 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.001 | 0.0007 | 0.0016 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0018 | 0.0017 | 0.0007 |
Brugia malayi | steroid hormone receptor | 0.001 | 0.0007 | 0.0016 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.001 | 0.0007 | 0.0007 |
Echinococcus multilocularis | carbonic anhydrase | 0.14 | 0.1646 | 0.4069 |
Schistosoma mansoni | cpg binding protein | 0.0028 | 0.0028 | 0.0028 |
Brugia malayi | isocitrate dehydrogenase | 0.0016 | 0.0014 | 0.0032 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0018 | 0.0017 | 0.0003 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.001 | 0.0007 | 0.0007 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.001 | 0.0007 | 0.0007 |
Echinococcus granulosus | cpg binding protein | 0.003 | 0.003 | 0.0073 |
Schistosoma mansoni | zinc finger protein | 0.0005 | 0.0001 | 0.0001 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.14 | 0.1646 | 0.4069 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.001 | 0.0007 | 0.0016 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.001 | 0.0007 | 0.0016 |
Echinococcus granulosus | carbonic anhydrase | 0.14 | 0.1646 | 0.4069 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0018 | 0.0017 | 0.004 |
Brugia malayi | nuclear hormone receptor | 0.001 | 0.0007 | 0.0016 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0014 | 0.0032 |
Echinococcus granulosus | transcription factor Dp 1 | 0.0037 | 0.0039 | 0.0095 |
Entamoeba histolytica | tyrosyl-DNA phosphodiesterase, putative | 0.0065 | 0.0072 | 0.0055 |
Loa Loa (eye worm) | hypothetical protein | 0.0313 | 0.0364 | 0.0898 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0005 | 0.0002 | 0.0002 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0005 | 0.0002 | 0.0002 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.3433 | 0.4043 | 0.4043 |
Schistosoma mansoni | nuclear hormone receptor | 0.0005 | 0.0001 | 0.0001 |
Schistosoma mansoni | ap endonuclease | 0.0018 | 0.0017 | 0.0017 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0005 | 0.0002 | 0.0002 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0016 | 0.0014 | 0.0014 |
Mycobacterium ulcerans | carbonic anhydrase | 0.3669 | 0.4322 | 0.4312 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0007 | 0.0016 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.0065 | 0.0072 | 0.0175 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.001 | 0.0007 | 0.0016 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.001 | 0.0007 | 0.0016 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0051 | 0.0055 | 0.0055 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0051 | 0.0055 | 0.0055 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0053 | 0.0058 | 0.0271 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0002 | 0.0002 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0065 | 0.0072 | 0.0143 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.001 | 0.0007 | 0.2307 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.001 | 0.0007 | 0.0016 |
Trichomonas vaginalis | conserved hypothetical protein | 0.3669 | 0.4322 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.001 | 0.0007 | 0.0016 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.001 | 0.0007 | 0.0016 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.001 | 0.0007 | 0.0016 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0065 | 0.0072 | 0.0143 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.001 | 0.0007 | 0.0016 |
Leishmania major | carbonic anhydrase family protein, putative | 0.8485 | 1 | 1 |
Plasmodium falciparum | carbonic anhydrase | 0.14 | 0.1646 | 1 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0051 | 0.0055 | 0.0134 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.3433 | 0.4043 | 1 |
Schistosoma mansoni | carbonic anhydrase-related | 0.14 | 0.1646 | 0.1646 |
Echinococcus multilocularis | carbonic anhydrase | 0.14 | 0.1646 | 0.4069 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.001 | 0.0007 | 0.0016 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0051 | 0.0055 | 0.0134 |
Schistosoma mansoni | hypothetical protein | 0.14 | 0.1646 | 0.1646 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0051 | 0.0055 | 0.0055 |
Echinococcus multilocularis | muscleblind protein | 0.0313 | 0.0364 | 0.0898 |
Echinococcus granulosus | muscleblind protein | 0.0313 | 0.0364 | 0.0898 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.001 | 0.0007 | 0.0016 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.001 | 0.0007 | 0.0016 |
Leishmania major | carbonic anhydrase-like protein | 0.3433 | 0.4043 | 0.4035 |
Loa Loa (eye worm) | hypothetical protein | 0.14 | 0.1646 | 0.4069 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0018 | 0.0017 | 0.0018 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.003 | 0.003 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0007 | 0.0003 | 0.0006 |
Schistosoma mansoni | nuclear receptor | 0.0005 | 0.0001 | 0.0001 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.001 | 0.0007 | 0.0016 |
Schistosoma mansoni | carbonic anhydrase-related | 0.14 | 0.1646 | 0.1646 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0007 | 0.0016 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.001 | 0.0007 | 0.0016 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0018 | 0.0017 | 0.5 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0016 | 0.0014 | 0.0032 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0007 | 0.0016 |
Schistosoma mansoni | carbonic anhydrase-related | 0.14 | 0.1646 | 0.1646 |
Brugia malayi | CXXC zinc finger family protein | 0.0028 | 0.0028 | 0.0068 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0051 | 0.0055 | 0.0134 |
Loa Loa (eye worm) | steroid hormone receptor | 0.001 | 0.0007 | 0.0016 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.001 | 0.0007 | 0.0007 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0005 | 0.0002 | 0.0002 |
Echinococcus multilocularis | FTZ F1 alpha | 0.001 | 0.0007 | 0.0016 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.001 | 0.0007 | 0.0016 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.001 | 0.0007 | 0.2307 |
Trichomonas vaginalis | conserved hypothetical protein | 0.3669 | 0.4322 | 1 |
Brugia malayi | Isocitrate dehydrogenase | 0.0016 | 0.0014 | 0.0032 |
Echinococcus multilocularis | carbonic anhydrase II | 0.3433 | 0.4043 | 1 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.001 | 0.0007 | 0.0007 |
Mycobacterium tuberculosis | Probable transmembrane carbonic anhydrase (carbonate dehydratase) (carbonic dehydratase) | 0.3669 | 0.4322 | 0.7611 |
Mycobacterium leprae | CARBONIC ANHYDRASE (CARBONATE DEHYDRATASE) (CARBONIC DEHYDRATASE) | 0.8485 | 1 | 0.5 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.001 | 0.0007 | 0.0016 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0005 | 0.0001 | 0.0001 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0051 | 0.0055 | 0.0134 |
Schistosoma mansoni | carbonic anhydrase | 0.8485 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.001 | 0.0007 | 0.0016 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.001 | 0.0007 | 0.0016 |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.0065 | 0.0072 | 0.0072 |
Schistosoma mansoni | thyroid hormone receptor | 0.001 | 0.0007 | 0.0007 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0007 | 0.0016 |
Echinococcus granulosus | carbonic anhydrase | 0.14 | 0.1646 | 0.4069 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0018 | 0.0017 | 0.0033 |
Mycobacterium ulcerans | carbonic anhydrase | 0.8485 | 1 | 1 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0018 | 0.0017 | 0.0007 |
Loa Loa (eye worm) | hypothetical protein | 0.14 | 0.1646 | 0.4069 |
Echinococcus granulosus | carbonic anhydrase | 0.14 | 0.1646 | 0.4069 |
Loa Loa (eye worm) | hypothetical protein | 0.0313 | 0.0364 | 0.0898 |
Mycobacterium tuberculosis | Beta-carbonic anhydrase CanB | 0.4816 | 0.5674 | 1 |
Brugia malayi | Muscleblind-like protein | 0.0313 | 0.0364 | 0.0898 |
Echinococcus multilocularis | carbonic anhydrase | 0.14 | 0.1646 | 0.4069 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0018 | 0.0017 | 0.5 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0007 | 0.0003 | 0.0003 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0014 | 0.0032 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0051 | 0.0055 | 0.0134 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.001 | 0.0007 | 0.0016 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0005 | 0.0002 | 0.0002 |
Echinococcus granulosus | carbonic anhydrase II | 0.3433 | 0.4043 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.14 | 0.1646 | 0.4069 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.3433 | 0.4043 | 0.4043 |
Schistosoma mansoni | coup transcription factor | 0.001 | 0.0007 | 0.0007 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0018 | 0.0017 | 0.5 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.001 | 0.0007 | 0.0007 |
Trypanosoma brucei | carbonic anhydrase-like protein | 0.3433 | 0.4043 | 1 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0028 | 0.0028 | 0.0068 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0313 | 0.0364 | 0.0898 |
Onchocerca volvulus | 0.001 | 0.0007 | 0.2307 | |
Brugia malayi | hypothetical protein | 0.0005 | 0.0002 | 0.0002 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.001 | 0.0007 | 0.0016 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.001 | 0.0007 | 0.0016 |
Brugia malayi | nuclear receptor NHR-88 | 0.001 | 0.0007 | 0.0016 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0006 | 0.0011 |
Trypanosoma brucei | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0065 | 0.0072 | 0.0143 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.001 | 0.0007 | 0.0007 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.001 | 0.0007 | 0.0007 |
Schistosoma mansoni | nuclear receptor | 0.0005 | 0.0001 | 0.0001 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.14 | 0.1646 | 0.4069 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0018 | 0.0017 | 0.0007 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0002 | 0.0002 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0005 | 0.0002 | 0.0002 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Potency (functional) | 29.0929 uM | PubChem BioAssay. qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-NT fibrosarcoma cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.