Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | STE/STE20/TAO protein kinase | 0.0441 | 0.9353 | 1 |
Onchocerca volvulus | 0.0073 | 0.1002 | 0.2166 | |
Loa Loa (eye worm) | glutaminase 2 | 0.0265 | 0.5348 | 0.5718 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.1002 | 0.1072 |
Mycobacterium ulcerans | glutaminase | 0.0265 | 0.5348 | 1 |
Echinococcus granulosus | serine:threonine protein kinase TAO1 | 0.0441 | 0.9353 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.0347 | 0.0371 |
Onchocerca volvulus | 0.0073 | 0.1002 | 0.2166 | |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.1002 | 0.1072 |
Brugia malayi | beta-lactamase family protein | 0.0073 | 0.1002 | 0.1072 |
Onchocerca volvulus | 0.0073 | 0.1002 | 0.2166 | |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0106 | 0.0113 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0463 | 0.0496 |
Brugia malayi | Pre-SET motif family protein | 0.0205 | 0.3986 | 0.4261 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0073 | 0.1002 | 0.1072 |
Loa Loa (eye worm) | glutaminase | 0.0265 | 0.5348 | 0.5718 |
Echinococcus multilocularis | geminin | 0.0165 | 0.3091 | 0.3305 |
Mycobacterium leprae | Probable lipase LipE | 0.0073 | 0.1002 | 0.5 |
Trichomonas vaginalis | set domain proteins, putative | 0.0233 | 0.4628 | 0.8345 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0347 | 0.0371 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0045 | 0.0347 | 0.0371 |
Mycobacterium leprae | conserved hypothetical protein | 0.0073 | 0.1002 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.1002 | 0.1072 |
Leishmania major | hypothetical protein, conserved | 0.0073 | 0.1002 | 0.5 |
Toxoplasma gondii | ABC1 family protein | 0.0073 | 0.1002 | 1 |
Brugia malayi | beta-lactamase | 0.0073 | 0.1002 | 0.1072 |
Brugia malayi | hypothetical protein | 0.0441 | 0.9353 | 1 |
Brugia malayi | glutaminase DH11.1 | 0.0265 | 0.5348 | 0.5718 |
Echinococcus multilocularis | serine:threonine protein kinase TAO1 | 0.0441 | 0.9353 | 1 |
Brugia malayi | Serine/threonine-protein kinase SULU | 0.0441 | 0.9353 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.005 | 0.0463 | 0.0496 |
Echinococcus granulosus | geminin | 0.0165 | 0.3091 | 0.3305 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0073 | 0.1002 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0106 | 0.0113 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0205 | 0.3986 | 0.4261 |
Loa Loa (eye worm) | beta-lactamase | 0.0073 | 0.1002 | 0.1072 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.005 | 0.0463 | 0.0496 |
Schistosoma mansoni | hypothetical protein | 0.0165 | 0.3091 | 0.3305 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.0347 | 0.0371 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0073 | 0.1002 | 0.1072 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0073 | 0.1002 | 0.1072 |
Schistosoma mansoni | hypothetical protein | 0.0165 | 0.3091 | 0.3305 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0034 | 0.0106 | 0.0113 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0073 | 0.1002 | 0.1072 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0073 | 0.1002 | 0.5 |
Schistosoma mansoni | glutaminase | 0.0265 | 0.5348 | 0.5718 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0441 | 0.9353 | 1 |
Brugia malayi | beta-lactamase family protein | 0.0073 | 0.1002 | 0.1072 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0045 | 0.0347 | 0.0371 |
Plasmodium vivax | hypothetical protein, conserved | 0.0073 | 0.1002 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.005 | 0.0463 | 0.0496 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0347 | 0.0371 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.1002 | 0.1072 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0347 | 0.0371 |
Trichomonas vaginalis | glutaminase, putative | 0.0265 | 0.5348 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.1002 | 0.1072 |
Onchocerca volvulus | 0.0233 | 0.4628 | 1 | |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.0347 | 0.0371 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0073 | 0.1002 | 0.5 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0073 | 0.1002 | 0.1072 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0073 | 0.1002 | 0.1072 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.1002 | 0.1072 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.0347 | 0.0371 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.