Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | ubiquitin-like modifier activating enzyme 2 | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | ubiquitin-activating enzyme E1, putative | 0.0035 | 0.0265 | 0.5 |
Plasmodium vivax | SUMO-activating enzyme subunit 2, putative | 0.0035 | 0.0265 | 0.5 |
Toxoplasma gondii | ThiF family protein | 0.0035 | 0.0265 | 0.5 |
Loa Loa (eye worm) | STE/STE20/TAO protein kinase | 0.0774 | 1 | 1 |
Entamoeba histolytica | ubiquitin-activating enzyme, putative | 0.0015 | 0 | 0.5 |
Echinococcus multilocularis | serine:threonine protein kinase TAO1 | 0.0774 | 1 | 1 |
Trypanosoma cruzi | ubiquitin-activating enzyme, putative | 0.0033 | 0.0242 | 0.9115 |
Leishmania major | ubiquitin-activating enzyme-like protein | 0.0035 | 0.0265 | 0.5 |
Brugia malayi | Serine/threonine-protein kinase SULU | 0.0774 | 1 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0774 | 1 | 1 |
Plasmodium falciparum | SUMO-activating enzyme subunit 2 | 0.0035 | 0.0265 | 0.5 |
Giardia lamblia | Ubiquitin-activating enzyme E1 1 | 0.0015 | 0 | 0.5 |
Trichomonas vaginalis | molybdopterin biosynthesis moeb protein, putative | 0.0015 | 0 | 0.5 |
Trypanosoma cruzi | ubiquitin-activating enzyme, putative | 0.0035 | 0.0265 | 1 |
Echinococcus granulosus | serine:threonine protein kinase TAO1 | 0.0774 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.