Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | methyltransferase protein 5 | 0.0056 | 0.0427 | 0.0427 |
Echinococcus granulosus | nicotinic acetylcholine receptor subunit alpha 8 | 0.0082 | 0.1509 | 0.1509 |
Entamoeba histolytica | hypothetical protein | 0.0086 | 0.1653 | 1 |
Loa Loa (eye worm) | nicotinic acetylcholine receptor alpha subunit | 0.0082 | 0.1509 | 0.113 |
Trypanosoma cruzi | arginine N-methyltransferase, putative | 0.0086 | 0.1653 | 1 |
Echinococcus granulosus | probable protein arginine n-methyltransferase | 0.0285 | 0.9885 | 0.9885 |
Echinococcus multilocularis | histone arginine methyltransferase CARMER | 0.0288 | 1 | 1 |
Loa Loa (eye worm) | Carm1-pending protein | 0.0288 | 1 | 1 |
Trypanosoma brucei | Protein arginine N-methyltransferase 1 catalytic subunit | 0.0086 | 0.1653 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.1509 | 0.113 |
Echinococcus granulosus | nicotinic acetylcholine receptor alpha subunit | 0.0082 | 0.1509 | 0.1509 |
Trichomonas vaginalis | protein arginine N-methyltransferase, putative | 0.0056 | 0.0427 | 1 |
Echinococcus multilocularis | protein arginine N methyltransferase 7 | 0.0056 | 0.0427 | 0.0427 |
Plasmodium vivax | protein arginine N-methyltransferase 1, putative | 0.0046 | 0 | 0.5 |
Echinococcus granulosus | histone arginine methyltransferase CARMER | 0.0288 | 1 | 1 |
Schistosoma mansoni | protein arginine n-methyltransferase | 0.0288 | 1 | 1 |
Leishmania major | arginine N-methyltransferase, type III, putative;with=GeneDB:Tb927.7.5490 | 0.0056 | 0.0427 | 0.5 |
Echinococcus granulosus | nicotinic acetylcholine receptor a11 subunit | 0.0082 | 0.1509 | 0.1509 |
Entamoeba histolytica | arginine N-methyltransferase protein, putative | 0.0086 | 0.1653 | 1 |
Echinococcus multilocularis | nicotinic acetylcholine receptor a11 subunit | 0.0082 | 0.1509 | 0.1509 |
Plasmodium falciparum | protein arginine N-methyltransferase 1 | 0.0046 | 0 | 0.5 |
Toxoplasma gondii | histone arginine methyltransferase PRMT4/CARM1 | 0.0288 | 1 | 1 |
Echinococcus multilocularis | nicotinic acetylcholine receptor subunit alpha 8 | 0.0082 | 0.1509 | 0.1509 |
Echinococcus granulosus | protein arginine N methyltransferase 7 | 0.0056 | 0.0427 | 0.0427 |
Trypanosoma cruzi | arginine N-methyltransferase, putative | 0.0086 | 0.1653 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0056 | 0.0427 | 0.0427 |
Echinococcus multilocularis | nicotinic acetylcholine receptor alpha subunit | 0.0082 | 0.1509 | 0.1509 |
Leishmania major | arginine N-methyltransferase, type I | 0.0056 | 0.0427 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.1653 | 0.128 |
Toxoplasma gondii | histone arginine methyltransferase PRMT3 | 0.0056 | 0.0427 | 0.0427 |
Trichomonas vaginalis | protein arginine N-methyltransferase, putative | 0.0056 | 0.0427 | 1 |
Brugia malayi | hypothetical protein | 0.0086 | 0.1653 | 0.128 |
Onchocerca volvulus | 0.0232 | 0.7674 | 1 | |
Trichomonas vaginalis | protein arginine N-methyltransferase, putative | 0.0056 | 0.0427 | 1 |
Toxoplasma gondii | bicoid-interacting protein BIN3 | 0.0056 | 0.0427 | 0.0427 |
Brugia malayi | nicotinic acetylcholine receptor alpha subunit, putative | 0.0082 | 0.1509 | 0.113 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.