Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0285 | 0.0923 | 0.5089 | |
Loa Loa (eye worm) | hypothetical protein | 0.0285 | 0.0923 | 0.0923 |
Loa Loa (eye worm) | trehalase | 0.0285 | 0.0923 | 0.0923 |
Onchocerca volvulus | 0.0379 | 0.1797 | 1 | |
Onchocerca volvulus | 0.0285 | 0.0923 | 0.5089 | |
Trichomonas vaginalis | trehalase, putative | 0.0285 | 0.0923 | 0.9817 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.0287 | 0.094 | 0.094 |
Brugia malayi | O-Glycosyl hydrolase family 30 protein | 0.0287 | 0.094 | 0.0065 |
Loa Loa (eye worm) | hypothetical protein | 0.0285 | 0.0923 | 0.0923 |
Onchocerca volvulus | 0.0285 | 0.0923 | 0.5089 | |
Loa Loa (eye worm) | TRE-2 protein | 0.0285 | 0.0923 | 0.0923 |
Loa Loa (eye worm) | trehalase | 0.0285 | 0.0923 | 0.0923 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0564 | 0.3524 | 0.3524 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0199 | 0.0113 | 0.1027 |
Plasmodium falciparum | conserved Plasmodium protein, unknown function | 0.0191 | 0.0037 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0287 | 0.094 | 1 |
Onchocerca volvulus | 0.0285 | 0.0923 | 0.5089 | |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0287 | 0.094 | 1 |
Onchocerca volvulus | 0.0285 | 0.0923 | 0.5089 | |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0287 | 0.094 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0285 | 0.0923 | 0.0923 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0287 | 0.094 | 1 |
Onchocerca volvulus | Trehalase homolog | 0.0285 | 0.0923 | 0.5089 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0287 | 0.094 | 1 |
Plasmodium vivax | hypothetical protein, conserved | 0.0191 | 0.0037 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0285 | 0.0923 | 0.0923 |
Loa Loa (eye worm) | TRE-1 protein | 0.0285 | 0.0923 | 0.0923 |
Loa Loa (eye worm) | hypothetical protein | 0.0624 | 0.4081 | 0.4081 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0287 | 0.094 | 1 |
Schistosoma mansoni | beta-galactosidase | 0.0624 | 0.4081 | 1 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0564 | 0.3524 | 1 |
Loa Loa (eye worm) | trehalase | 0.0285 | 0.0923 | 0.0923 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0285 | 0.0923 | 0.9817 |
Echinococcus granulosus | beta galactosidase | 0.0624 | 0.4081 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0199 | 0.0113 | 0.1027 |
Loa Loa (eye worm) | hypothetical protein | 0.0285 | 0.0923 | 0.0923 |
Echinococcus multilocularis | beta galactosidase | 0.0624 | 0.4081 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.