Detailed information for compound 1804234

Basic information

Technical information
  • TDR Targets ID: 1804234
  • Name: 5-dimethylamino-2-propyl-1,3-dithiane-2-carbo nitrile
  • MW: 230.393 | Formula: C10H18N2S2
  • H donors: 0 H acceptors: 1 LogP: 2.39 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCC1(C#N)SCC(CS1)N(C)C
  • InChi: 1S/C10H18N2S2/c1-4-5-10(8-11)13-6-9(7-14-10)12(2)3/h9H,4-7H2,1-3H3
  • InChiKey: OSMPLFNENCOKQP-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.1025 0.1076
Trichomonas vaginalis PIKK family atypical protein kinase 0.0072 0.0639 0.0546
Trichomonas vaginalis PIKK family atypical protein kinase 0.0072 0.0639 0.0546
Trichomonas vaginalis AGC family protein kinase 0.0089 0.1025 0.1076
Echinococcus multilocularis dual specificity 0.0386 0.7525 0.7335
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.1025 0.1076
Onchocerca volvulus Putative endochitinase 0.0098 0.1219 0.2052
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0199 0.3431 0.438
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0095 0.1137 0.0567
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0131 0.1938 0.111
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.1025 0.1076
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.1025 0.1076
Loa Loa (eye worm) hypothetical protein 0.0068 0.056 0.0208
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0131 0.1938 0.1427
Trichomonas vaginalis PIKK family atypical protein kinase 0.0072 0.0639 0.0546
Loa Loa (eye worm) acetylcholinesterase 1 0.0133 0.1986 0.1688
Trichomonas vaginalis PIKK family atypical protein kinase 0.0059 0.0354 0.0156
Trichomonas vaginalis AGC family protein kinase 0.0089 0.1025 0.1076
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.1025 0.1076
Loa Loa (eye worm) cuticular endochitinase 0.0088 0.0987 0.0652
Trichomonas vaginalis PIKK family atypical protein kinase 0.0072 0.0639 0.0546
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.1025 0.1076
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0091 0.1063 0.0982
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.1025 0.1076
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.037 0.7166 0.6935
Trypanosoma cruzi serine/threonine protein kinase, putative 0.0089 0.1025 0.0929
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.1025 0.1076
Trichomonas vaginalis PIKK family atypical protein kinase 0.0063 0.0455 0.0294
Schistosoma mansoni hypothetical protein 0.0495 0.9917 1
Echinococcus multilocularis cyclin dependent kinase 9 0.0089 0.1025 0.0093
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0242 0.0002
Giardia lamblia Kinase, CAMK CAMKL 0.0089 0.1025 0.1146
Trypanosoma brucei protein kinase, putative 0.0089 0.1025 0.1362
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.1025 0.1076
Echinococcus multilocularis acetylcholinesterase 0.0133 0.1986 0.1164
Loa Loa (eye worm) hypothetical protein 0.0133 0.1986 0.1688
Echinococcus granulosus acetylcholinesterase 0.0133 0.1986 0.1164
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0076 0.0741 0.0985
Brugia malayi Hepatocellular carcinoma-associated antigen 59 family protein 0.0139 0.2116 0.1618
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.007 0.061 0.0507
Loa Loa (eye worm) hypothetical protein 0.0133 0.1986 0.1688
Entamoeba histolytica protein kinase domain containing protein 0.0386 0.7525 1
Echinococcus multilocularis acetylcholinesterase 0.0133 0.1986 0.1164
Entamoeba histolytica hypothetical protein 0.016 0.2566 0.2828
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.016 0.2566 0.2828
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.1025 0.1076
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.1025 0.1076
Trichomonas vaginalis CMGC family protein kinase 0.0386 0.7525 1
Mycobacterium tuberculosis Possible chitinase 0.0075 0.0704 0.5
Onchocerca volvulus 0.0139 0.2116 1
Brugia malayi cyclin-dependent kinase 7 homolog 0.0089 0.1025 0.0445
Echinococcus granulosus serine:threonine protein kinase haspin 0.0495 0.9917 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0072 0.0639 0.0546
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0199 0.3431 0.4287
Echinococcus multilocularis carboxylesterase 5A 0.0133 0.1986 0.1164
Entamoeba histolytica protein kinase, putative 0.0386 0.7525 1
Trypanosoma brucei Mitogen-activated protein kinase 10, putative 0.0089 0.1025 0.1362
Trichomonas vaginalis CMGC family protein kinase 0.0386 0.7525 1
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0199 0.3431 0.408
Trichomonas vaginalis PIKK family atypical protein kinase 0.0076 0.0739 0.0684
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0095 0.1137 0.0584
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.1025 0.1076
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0386 0.7525 1
Brugia malayi Endochitinase 0.0098 0.1219 0.0654
Echinococcus multilocularis Hepatocellular carcinoma associated antigen 59 0.0139 0.2116 0.1309
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.1025 0.1076
Loa Loa (eye worm) CMGC/CDK/CRK7 protein kinase 0.0089 0.1025 0.069
Leishmania major chitinase 0.0088 0.0987 0.0363
Echinococcus multilocularis dual specificity 0.0386 0.7525 0.7335
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.0497 0.0352
Echinococcus granulosus serine:threonine protein kinase haspin 0.0495 0.9917 1
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.1025 0.1076
Trichomonas vaginalis PIKK family atypical protein kinase 0.0058 0.0343 0.014
Trichomonas vaginalis CMGC family protein kinase 0.0386 0.7525 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0076 0.0739 0.0684
Loa Loa (eye worm) hypothetical protein 0.0139 0.2116 0.1822
Trichomonas vaginalis CMGC family protein kinase 0.0089 0.1025 0.1076
Trichomonas vaginalis AGC family protein kinase 0.0089 0.1025 0.1076
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.1025 0.1076
Giardia lamblia Kinase, CMGC DYRK 0.0386 0.7525 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0242 0.0002
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0095 0.1137 0.0218
Echinococcus granulosus Cell division cycle 2 protein kinase 0.0089 0.1025 0.0093
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.1025 0.1076
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.007 0.061 0.0811
Trichomonas vaginalis PIKK family atypical protein kinase 0.0076 0.0739 0.0684
Echinococcus granulosus serine:threonine protein kinase NLK 0.0089 0.1025 0.0093
Trichomonas vaginalis CMGC family protein kinase 0.0089 0.1025 0.1076
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.1025 0.1076
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.1025 0.1076
Echinococcus granulosus mitogen activated protein kinase 15 0.0089 0.1025 0.0093
Mycobacterium ulcerans chitinase/cellulase 0.0075 0.0704 0.5
Echinococcus multilocularis serine:threonine protein kinase haspin 0.0495 0.9917 1
Brugia malayi GSG2 0.0495 0.9917 1
Brugia malayi hypothetical protein 0.0495 0.9917 1
Echinococcus granulosus carboxylesterase 5A 0.0133 0.1986 0.1164
Giardia lamblia Kinase, CAMK CAMKL 0.0089 0.1025 0.1146
Loa Loa (eye worm) microfilarial chitinase 0.0085 0.0936 0.0598
Schistosoma mansoni hypothetical protein 0.0086 0.0941 0.0356
Trichomonas vaginalis AGC family protein kinase 0.0089 0.1025 0.1076
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.1025 0.1076
Trichomonas vaginalis CMGC family protein kinase 0.0089 0.1025 0.1076
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.1025 0.1076
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0242 0.0002
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0091 0.1063 0.073
Echinococcus multilocularis serine:threonine protein kinase haspin 0.0495 0.9917 1
Loa Loa (eye worm) hypothetical protein 0.0075 0.0704 0.0358
Trichomonas vaginalis CMGC family protein kinase 0.0386 0.7525 1
Entamoeba histolytica cell division protein kinase 2, putative 0.0089 0.1025 0.0599
Loa Loa (eye worm) haspin protein kinase 0.0495 0.9917 0.9914
Loa Loa (eye worm) phosphatidylinositol 3 0.033 0.63 0.6162
Brugia malayi phosphoinositide 3'-hydroxykinase p110-alpha subunit, putative 0.017 0.2801 0.2354
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0095 0.1137 0.1511
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.1025 0.1076
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0092 0.1072 0.0668
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.007 0.061 0.035
Loa Loa (eye worm) carboxylesterase 0.0133 0.1986 0.1688
Plasmodium vivax hypothetical protein, conserved 0.0139 0.2116 1
Brugia malayi Protein kinase domain containing protein 0.0089 0.1025 0.0445
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.1025 0.1076
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0386 0.7525 0.7433
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0095 0.1137 0.1086
Loa Loa (eye worm) haspin protein kinase 0.0495 0.9917 0.9914
Echinococcus granulosus dual specificity 0.0386 0.7525 0.7335
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.037 0.7166 0.7044
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0095 0.1137 0.0584
Entamoeba histolytica phosphatidylinositol 3-kinase 1, putative 0.0188 0.318 0.3717
Entamoeba histolytica hypothetical protein 0.0091 0.1063 0.0655
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.1025 0.1076
Trichomonas vaginalis AGC family protein kinase 0.0089 0.1025 0.1076
Loa Loa (eye worm) hypothetical protein 0.0087 0.098 0.0644
Trichomonas vaginalis PIKK family atypical protein kinase 0.0059 0.0354 0.0156
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.1025 0.1076
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0131 0.1938 0.111
Giardia lamblia Kinase, CAMK CAMKL 0.0089 0.1025 0.1146
Loa Loa (eye worm) chitinase I 0.0088 0.0987 0.0652
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.1025 0.1076
Trichomonas vaginalis CMGC family protein kinase 0.0089 0.1025 0.1076
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0139 0.2104 0.2558
Schistosoma mansoni serine/threonine protein kinase 0.0091 0.1063 0.0487
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0386 0.7525 1
Entamoeba histolytica hypothetical protein 0.0086 0.0941 0.0479
Trichomonas vaginalis CMGC family protein kinase 0.0386 0.7525 1
Loa Loa (eye worm) phosphatidylinositol 3 0.0095 0.1137 0.0807
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0386 0.7525 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0095 0.1137 0.1231
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.1025 0.1076
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.1025 0.1076
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.1025 0.1076
Brugia malayi endochitinase 0.0098 0.1219 0.0654
Giardia lamblia GTOR 0.0095 0.1137 0.1299
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0048 0.0112 0.0149
Echinococcus granulosus dual specificity 0.0386 0.7525 0.7335
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0095 0.1137 0.1511
Toxoplasma gondii hypothetical protein 0.0139 0.2116 0.2145
Entamoeba histolytica protein kinase domain containing protein 0.0091 0.1063 0.0655
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0095 0.1137 0.1086
Brugia malayi Cell division protein kinase 2 0.0089 0.1025 0.0445
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.007 0.061 0.0507
Schistosoma mansoni serine/threonine protein kinase 0.0386 0.7525 0.743
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.1025 0.1076
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.1025 0.1076
Trichomonas vaginalis protein kinase atmrk1, putative 0.0089 0.1025 0.1076
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.0199 0.3431 0.438
Trichomonas vaginalis PIKK family atypical protein kinase 0.0095 0.1137 0.1231
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0091 0.1063 0.1413
Echinococcus granulosus cyclin dependent kinase 9 0.0089 0.1025 0.0093
Entamoeba histolytica protein kinase domain containing protein 0.0089 0.1025 0.0599
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.1025 0.1076
Echinococcus granulosus dual specificity 0.0386 0.7525 0.7335
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0091 0.1063 0.0982
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0242 0.0002
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.1025 0.1076
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.1025 0.1076
Trypanosoma cruzi Mitogen-activated protein kinase 10, putative 0.0089 0.1025 0.0929
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.1025 0.1076
Entamoeba histolytica protein kinase, putative 0.0091 0.1063 0.0655
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0089 0.1025 0.069
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0199 0.3431 0.4287
Plasmodium falciparum conserved protein, unknown function 0.0139 0.2116 1
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0095 0.1137 0.0762
Trichomonas vaginalis PIKK family atypical protein kinase 0.0076 0.0739 0.0684
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0386 0.7525 1
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.1025 0.1076
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.1025 0.1076
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.0099 0.1238 0.1436
Brugia malayi Carboxylesterase family protein 0.0133 0.1986 0.1479
Trichomonas vaginalis AGC family protein kinase 0.0089 0.1025 0.1076
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0199 0.3431 0.3032
Echinococcus multilocularis serine:threonine protein kinase NLK 0.0089 0.1025 0.0093
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0091 0.1063 0.0475
Onchocerca volvulus Putative endochitinase 0.0098 0.1219 0.2052
Schistosoma mansoni serine/threonine protein kinase 0.0089 0.1025 0.0445
Trichomonas vaginalis PIKK family atypical protein kinase 0.0095 0.1137 0.1231
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.1025 0.1076
Trichomonas vaginalis CMGC family protein kinase 0.0386 0.7525 1
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0095 0.1137 0.0567
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.007 0.061 0.0507
Brugia malayi endochitinase 0.0088 0.0987 0.0405
Trichomonas vaginalis PIKK family atypical protein kinase 0.0082 0.0853 0.084
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0095 0.1137 0.0762
Echinococcus granulosus serine:threonine protein kinase haspin 0.0495 0.9917 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0072 0.0639 0.0546
Schistosoma mansoni protein kinase 0.0089 0.1025 0.0445
Onchocerca volvulus 0.0139 0.2116 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0072 0.0639 0.0546
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.1025 0.1076
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.037 0.7166 0.6935
Trichomonas vaginalis PIKK family atypical protein kinase 0.0058 0.0343 0.014
Trichomonas vaginalis serine/threonine kinase, putative 0.0089 0.1025 0.1076
Onchocerca volvulus Putative endochitinase 0.0098 0.1219 0.2052
Mycobacterium ulcerans chitinase/cellulase 0.0075 0.0704 0.5
Trypanosoma cruzi target of rapamycin kinase 3 0.0076 0.0741 0.0533
Leishmania major serine/threonine kinase-like protein, putative 0.0089 0.1025 0.0418
Echinococcus granulosus dual specificity 0.0091 0.1063 0.0135
Brugia malayi Carboxylesterase family protein 0.0133 0.1986 0.1479
Loa Loa (eye worm) hypothetical protein 0.0139 0.2116 0.1822
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.1025 0.1076
Echinococcus granulosus Hepatocellular carcinoma associated antigen 59 0.0139 0.2116 0.1309
Loa Loa (eye worm) hypothetical protein 0.0087 0.098 0.0644
Trichomonas vaginalis PIKK family atypical protein kinase 0.0059 0.0354 0.0156
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0139 0.2104 0.2558
Trypanosoma cruzi Mitogen-activated protein kinase 10, putative 0.0089 0.1025 0.0929
Schistosoma mansoni serine/threonine kinase 0.0089 0.1025 0.0445
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0133 0.1986 0.1479
Schistosoma mansoni hypothetical protein 0.0139 0.2116 0.1618
Brugia malayi Protein kinase domain containing protein 0.0091 0.1063 0.0487
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0386 0.7525 0.743
Trichomonas vaginalis G protein-coupled receptor kinase, putative 0.0089 0.1025 0.1076
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.1025 0.1076
Entamoeba histolytica protein kinase, putative 0.0091 0.1063 0.0655
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.1025 0.1076
Echinococcus multilocularis dual specificity 0.0386 0.7525 0.7335
Entamoeba histolytica chitinase, putative 0.0088 0.0987 0.0545
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0095 0.1137 0.0218
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.1025 0.1076
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.1025 0.1076
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0199 0.3431 0.438
Echinococcus granulosus acetylcholinesterase 0.0133 0.1986 0.1164
Leishmania major mitogen-activated protein kinase, putative,map kinase-like protein 0.0089 0.1025 0.0418
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.1025 0.1076
Trichomonas vaginalis PIKK family atypical protein kinase 0.0076 0.0739 0.0684
Loa Loa (eye worm) hypothetical protein 0.0131 0.1938 0.1638
Echinococcus multilocularis Cell division cycle 2 protein kinase 0.0089 0.1025 0.0093
Trichomonas vaginalis AGC family protein kinase 0.0089 0.1025 0.1076
Echinococcus multilocularis dual specificity 0.0091 0.1063 0.0135

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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