TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 781.049 | Formula: C30H17ClF8N4O6S2
H donors: 2 H acceptors: 4 LogP: 9.14 Rotable bonds: 17
Rule of 5 violations (Lipinski): 2
SMILES: O=C(N(c1ccc(cc1)OC(F)(F)F)SSN(C(=O)NC(=O)c1c(F)cccc1F)c1ccc(cc1)OC(F)(F)F)NC(=O)c1ccccc1Cl
InChi: 1S/C30H17ClF8N4O6S2/c31-21-5-2-1-4-20(21)25(44)40-27(46)42(16-8-12-18(13-9-16)48-29(34,35)36)50-51-43(17-10-14-19(15-11-17)49-30(37,38)39)28(47)41-26(45)24-22(32)6-3-7-23(24)33/h1-15H,(H,40,44,46)(H,41,45,47)
InChiKey: RHLLDHRZUSTHRZ-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Schistosoma mansoni	hypothetical protein	0.0043	0.004	0.0036
Loa Loa (eye worm)	latrophilin receptor protein 2	0.0017	0.0004	0.0004
Schistosoma mansoni	hypothetical protein	0.0043	0.004	0.0036
Trypanosoma brucei	phosphatidylinositol kinase related protein, putative	0.0029	0.002	1
Schistosoma mansoni	tar DNA-binding protein	0.0141	0.0172	0.0168
Echinococcus multilocularis	Transcription factor, JmjC domain containing protein	0.0102	0.0119	0.0116
Schistosoma mansoni	cpg binding protein	0.0064	0.0068	0.0064
Loa Loa (eye worm)	hypothetical protein	0.0045	0.0042	0.0042
Trypanosoma brucei	phosphatidylinositol 3-kinase, putative	0.0021	0.001	0.2528
Leishmania major	target of rapamycin (TOR) kinase 2, putative	0.0021	0.001	0.3808
Toxoplasma gondii	PHD-finger domain-containing protein	0.0031	0.0023	0.1242
Schistosoma mansoni	bromodomain-containing nuclear protein 1 brd1	0.0031	0.0023	0.0019
Mycobacterium ulcerans	long-chain-fatty-acid-CoA ligase	0.0025	0.0016	1
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0021	0.001	0.2122
Leishmania major	4-coumarate:coa ligase-like protein	0.0025	0.0016	1
Echinococcus granulosus	Niemann Pick C1 protein	0.0105	0.0123	0.0121
Schistosoma mansoni	hypothetical protein	0.0043	0.004	0.0036
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0021	0.001	0.2122
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0021	0.001	0.2122
Trypanosoma cruzi	Phosphatidylinositol 3-kinase tor2	0.0021	0.001	0.2528
Mycobacterium leprae	PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE)	0.0025	0.0016	0.5
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0021	0.001	0.2122
Trypanosoma cruzi	phosphatidylinositol kinase related protein, putative	0.0029	0.002	1
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0029	0.002	0.4685
Plasmodium vivax	acyl-CoA synthetase, putative	0.0019	0.0007	0.2837
Echinococcus multilocularis	isocitrate dehydrogenase	0.0018	0.0006	0.0003
Echinococcus multilocularis	GPCR, family 2	0.0017	0.0004	0.0001
Echinococcus multilocularis	dnaJ subfamily B	0.0909	0.1214	0.1211
Echinococcus granulosus	peregrin	0.0031	0.0023	0.0021
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0021	0.001	0.2122
Entamoeba histolytica	acyl-CoA synthetase, putative	0.0025	0.0016	0.0513
Echinococcus multilocularis	NADP dependent isocitrate dehydrogenase	0.0018	0.0006	0.0003
Echinococcus multilocularis	diuretic hormone 44 receptor GPRdih2	0.0017	0.0004	0.0001
Loa Loa (eye worm)	hypothetical protein	0.0019	0.0007	0.0007
Schistosoma mansoni	hypothetical protein	0.0031	0.0023	0.0019
Toxoplasma gondii	FATC domain-containing protein	0.0029	0.002	0.102
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0021	0.001	0.2122
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0021	0.001	0.2122
Brugia malayi	jmjC domain containing protein	0.0102	0.0119	0.0119
Echinococcus granulosus	alpha 16 mannosyl glycoprotein	0.7393	1	1
Echinococcus multilocularis	isocitrate dehydrogenase 2 (NADP+)	0.0018	0.0006	0.0003
Echinococcus granulosus	Transcription factor JmjC domain containing protein	0.0102	0.0119	0.0116
Trypanosoma cruzi	target of rapamycin kinase 3	0.0021	0.001	0.2528
Brugia malayi	CHE-14 protein	0.0045	0.0042	0.0042
Schistosoma mansoni	tar DNA-binding protein	0.0141	0.0172	0.0168
Schistosoma mansoni	jumonji domain containing protein	0.0081	0.0091	0.0087
Brugia malayi	Calcitonin receptor-like protein seb-1	0.0053	0.0053	0.0053
Echinococcus multilocularis	NADP dependent isocitrate dehydrogenase	0.0018	0.0006	0.0003
Brugia malayi	RNA binding protein	0.0141	0.0172	0.0172
Toxoplasma gondii	target of rapamycin (TOR), putative	0.0021	0.001	0.0258
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0056	0.0056
Schistosoma mansoni	ataxia telangiectasia mutated (atm)	0.0029	0.002	0.0016
Loa Loa (eye worm)	hypothetical protein	0.0025	0.0015	0.0015
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0021	0.001	0.2122
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0021	0.001	0.2122
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0021	0.001	0.2122
Brugia malayi	TAR-binding protein	0.0141	0.0172	0.0172
Mycobacterium ulcerans	fatty-acid-CoA ligase	0.0025	0.0016	1
Loa Loa (eye worm)	abnormal chemotaxis protein 14	0.0045	0.0042	0.0042
Echinococcus multilocularis	protein patched	0.0045	0.0042	0.004
Loa Loa (eye worm)	hypothetical protein	0.0019	0.0007	0.0007
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0021	0.001	0.2122
Echinococcus multilocularis	PHD finger protein rhinoceros	0.0031	0.0023	0.0021
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0021	0.001	0.2122
Trichomonas vaginalis	conserved hypothetical protein	0.0045	0.0042	1
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0021	0.001	0.2122
Loa Loa (eye worm)	hypothetical protein	0.0019	0.0007	0.0007
Entamoeba histolytica	acyl-coA synthetase, putative	0.0025	0.0016	0.0513
Echinococcus multilocularis	histone lysine N methyltransferase MLL3	0.002	0.0008	0.0005
Trypanosoma brucei	phosphatidylinositol 4-kinase, putative	0.0021	0.001	0.2528
Leishmania major	4-coumarate:coa ligase-like protein	0.0025	0.0016	1
Loa Loa (eye worm)	hypothetical protein	0.0025	0.0016	0.0016
Schistosoma mansoni	mixed-lineage leukemia protein mll	0.0026	0.0017	0.0012
Mycobacterium leprae	PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE)	0.0025	0.0016	0.5
Schistosoma mansoni	hypothetical protein	0.0036	0.0031	0.0026
Echinococcus multilocularis	serine protein kinase ATM	0.0029	0.002	0.0017
Echinococcus multilocularis	lysine specific demethylase 5A	0.0038	0.0032	0.0029
Schistosoma mansoni	cpg binding protein	0.0067	0.0073	0.0069
Entamoeba histolytica	acyl-CoA synthetase, putative	0.0025	0.0016	0.0513
Loa Loa (eye worm)	histone methyltransferase	0.002	0.0008	0.0008
Mycobacterium tuberculosis	Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP)	0.0018	0.0006	0.0622
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0053	0.0053
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0025	0.0016	1
Schistosoma mansoni	mixed-lineage leukemia protein mll	0.0135	0.0165	0.0161
Schistosoma mansoni	beta-12-n-acetylglucosaminyltransferase II	0.7393	1	1
Brugia malayi	PHD-finger family protein	0.0031	0.0023	0.0023
Brugia malayi	AMP-binding enzyme family protein	0.0025	0.0016	0.0016
Schistosoma mansoni	patched 1	0.0045	0.0042	0.0038
Echinococcus multilocularis	expressed conserved protein	0.0099	0.0115	0.0112
Schistosoma mansoni	tar DNA-binding protein	0.0141	0.0172	0.0168
Onchocerca volvulus	Alhambra homolog	0.0031	0.0023	0.1503
Schistosoma mansoni	jumonji/arid domain-containing protein	0.0041	0.0037	0.0033
Brugia malayi	latrophilin 2 splice variant baaae	0.0036	0.0031	0.0031
Brugia malayi	AMP-binding enzyme family protein	0.0025	0.0016	0.0016
Echinococcus multilocularis	protein dispatched 1	0.0051	0.0051	0.0048
Leishmania major	target of rapamycin (TOR) kinase 1, putative	0.0021	0.001	0.3808
Echinococcus granulosus	cadherin EGF LAG seven pass G type receptor	0.0017	0.0004	0.0001
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0021	0.001	0.2122
Echinococcus granulosus	PHD finger protein rhinoceros	0.0031	0.0023	0.0021
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0021	0.001	0.2122
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0021	0.001	0.2122
Schistosoma mansoni	tar DNA-binding protein	0.0141	0.0172	0.0168
Plasmodium falciparum	phd finger protein, putative	0.0031	0.0023	1
Loa Loa (eye worm)	jmjC domain-containing protein	0.0064	0.0068	0.0068
Schistosoma mansoni	hypothetical protein	0.0909	0.1214	0.121
Giardia lamblia	PHD finger protein 15	0.0031	0.0023	1
Loa Loa (eye worm)	hypothetical protein	0.0031	0.0023	0.0023
Leishmania major	4-coumarate:coa ligase-like protein	0.0025	0.0016	1
Loa Loa (eye worm)	hypothetical protein	0.0019	0.0007	0.0007
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0021	0.001	0.2122
Toxoplasma gondii	PHD-finger domain-containing protein	0.0031	0.0023	0.1242
Brugia malayi	Corticotropin releasing factor receptor 2 precursor, putative	0.0053	0.0053	0.0053
Leishmania major	phosphatidylinositol 3-related kinase, putative	0.0021	0.001	0.3808
Brugia malayi	F/Y-rich N-terminus family protein	0.003	0.0021	0.0021
Loa Loa (eye worm)	PHD-finger family protein	0.0031	0.0023	0.0023
Echinococcus granulosus	sterol regulatory element binding protein	0.0045	0.0042	0.004
Brugia malayi	RNA recognition motif domain containing protein	0.0141	0.0172	0.0172
Echinococcus granulosus	Niemann Pick C1 protein	0.015	0.0184	0.0182
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0021	0.001	0.2122
Echinococcus granulosus	serine protein kinase ATM	0.0029	0.002	0.0017
Plasmodium falciparum	isocitrate dehydrogenase [NADP], mitochondrial	0.0018	0.0006	0.2503
Brugia malayi	CXXC zinc finger family protein	0.0064	0.0068	0.0068
Loa Loa (eye worm)	hypothetical protein	0.0105	0.0123	0.0123
Trypanosoma brucei	target of rapamycin kinase 3, putative	0.0021	0.001	0.2528
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0021	0.001	0.2122
Brugia malayi	isocitrate dehydrogenase	0.0018	0.0006	0.0006
Schistosoma mansoni	cpg binding protein	0.0067	0.0073	0.0069
Loa Loa (eye worm)	RNA binding protein	0.0141	0.0172	0.0172
Mycobacterium ulcerans	acyl-CoA synthetase	0.0025	0.0016	1
Trypanosoma brucei	Phosphatidylinositol 3-kinase tor1	0.0021	0.001	0.2528
Brugia malayi	Bromodomain containing protein	0.0031	0.0023	0.0023
Schistosoma mansoni	phosphatidylinositol 3-and 4-kinase	0.0021	0.001	0.0006
Echinococcus multilocularis	cpg binding protein	0.0067	0.0073	0.007
Echinococcus multilocularis	FKBP12 rapamycin complex associated protein	0.0021	0.001	0.0007
Echinococcus multilocularis	cadherin EGF LAG seven pass G type receptor	0.0017	0.0004	0.0001
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0021	0.001	0.2122
Trypanosoma cruzi	phosphatidylinositol kinase related protein, putative	0.0025	0.0015	0.6152
Brugia malayi	jmjC domain containing protein	0.0041	0.0037	0.0037
Chlamydia trachomatis	acylglycerophosphoethanolamine acyltransferase	0.0019	0.0007	0.5
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0021	0.001	0.2122
Echinococcus granulosus	GPCR family 2	0.0017	0.0004	0.0001
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0021	0.001	0.2122
Echinococcus granulosus	phosphatidylinositol 3 and 4 kinase	0.0021	0.001	0.0007
Schistosoma mansoni	tar DNA-binding protein	0.0141	0.0172	0.0168
Schistosoma mansoni	NADP-specific isocitrate dehydrogenase	0.0018	0.0006	0.0002
Loa Loa (eye worm)	hypothetical protein	0.0025	0.0016	0.0016
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0021	0.001	0.2122
Echinococcus multilocularis	peregrin	0.0031	0.0023	0.0021
Echinococcus granulosus	FKBP12 rapamycin complex associated protein	0.0021	0.001	0.0007
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0021	0.001	0.2122
Trypanosoma cruzi	phosphatidylinositol 3-related kinase, putative	0.0021	0.001	0.2528
Leishmania major	phosphatidylinositol 3-kinase, putative	0.0021	0.001	0.3808
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0021	0.001	0.2122
Echinococcus granulosus	tar DNA binding protein	0.0141	0.0172	0.0169
Schistosoma mansoni	hypothetical protein	0.0043	0.004	0.0036
Loa Loa (eye worm)	isocitrate dehydrogenase	0.0018	0.0006	0.0006
Echinococcus granulosus	histone lysine N methyltransferase MLL3	0.002	0.0008	0.0005
Echinococcus granulosus	jumonji domain containing protein	0.0043	0.004	0.0037
Brugia malayi	Isocitrate dehydrogenase	0.0018	0.0006	0.0006
Leishmania major	phosphatidylinositol kinase related protein, putative	0.0021	0.001	0.3866
Brugia malayi	Phosphatidylinositol 3- and 4-kinase family protein	0.0029	0.002	0.002
Brugia malayi	Niemann-Pick C1 protein precursor	0.0105	0.0123	0.0123
Schistosoma mansoni	jumonji/arid domain-containing protein	0.0041	0.0037	0.0033
Echinococcus granulosus	lysine specific demethylase 5A	0.0041	0.0037	0.0034
Echinococcus multilocularis	Niemann Pick C1 protein	0.0105	0.0123	0.0121
Trypanosoma brucei	phosphatidylinositol 3-related kinase, putative	0.0021	0.001	0.2528
Onchocerca volvulus		0.0064	0.0068	1
Loa Loa (eye worm)	jmjC domain-containing protein	0.0041	0.0037	0.0037
Echinococcus multilocularis	NADP dependent isocitrate dehydrogenase	0.0018	0.0006	0.0003
Loa Loa (eye worm)	hypothetical protein	0.0025	0.0016	0.0016
Schistosoma mansoni	niemann-pick C1 (NPC1)	0.0106	0.0126	0.0122
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0021	0.001	0.2122
Trypanosoma cruzi	phosphatidylinositol kinase related protein, putative	0.0021	0.001	0.2567
Loa Loa (eye worm)	hypothetical protein	0.0019	0.0007	0.0007
Echinococcus multilocularis	jumonji domain containing protein	0.0043	0.004	0.0037
Echinococcus granulosus	NADP dependent isocitrate dehydrogenase	0.0018	0.0006	0.0003
Mycobacterium tuberculosis	Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase)	0.0019	0.0007	0.139
Mycobacterium ulcerans	hypothetical protein	0.0025	0.0016	1
Mycobacterium ulcerans	acyl-CoA synthetase	0.0025	0.0016	1
Loa Loa (eye worm)	RNA recognition domain-containing protein domain-containing protein	0.0141	0.0172	0.0172
Echinococcus multilocularis	tar DNA binding protein	0.0141	0.0172	0.0169
Entamoeba histolytica	hypothetical protein	0.0029	0.002	0.0932
Loa Loa (eye worm)	hypothetical protein	0.0017	0.0004	0.0004
Trypanosoma cruzi	phosphatidylinositol 3-related kinase, putative	0.0021	0.001	0.2528
Echinococcus granulosus	Protein patched homolog 1	0.0045	0.0042	0.004
Echinococcus granulosus	cpg binding protein	0.0067	0.0073	0.007
Entamoeba histolytica	Niemann-Pick C1 protein, putative	0.0105	0.0123	1
Loa Loa (eye worm)	phosphatidylinositol 3	0.0021	0.001	0.001
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0021	0.001	0.2122
Trypanosoma cruzi	Phosphatidylinositol 3-kinase tor1	0.0021	0.001	0.2528
Echinococcus multilocularis	Niemann Pick C1 protein	0.015	0.0184	0.0182
Loa Loa (eye worm)	CXXC zinc finger family protein	0.0064	0.0068	0.0068
Plasmodium vivax	hypothetical protein, conserved	0.0031	0.0023	1
Brugia malayi	calcium-independent alpha-latrotoxin receptor 2, putative	0.0017	0.0004	0.0004
Echinococcus granulosus	diuretic hormone 44 receptor GPRdih2	0.0017	0.0004	0.0001
Echinococcus multilocularis	alpha 1,6 mannosyl glycoprotein	0.7393	1	1
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0053	0.0053
Echinococcus granulosus	dnaJ subfamily B	0.0909	0.1214	0.1211
Loa Loa (eye worm)	hypothetical protein	0.0036	0.0031	0.0031
Mycobacterium tuberculosis	Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase)	0.0025	0.0016	1
Brugia malayi	Phosphatidylinositol 3- and 4-kinase family protein	0.0021	0.001	0.001
Brugia malayi	Phosphatidylinositol 3- and 4-kinase family protein	0.0021	0.001	0.001
Loa Loa (eye worm)	TAR-binding protein	0.0141	0.0172	0.0172
Plasmodium falciparum	acyl-CoA synthetase	0.0019	0.0007	0.2837
Brugia malayi	AMP-binding enzyme family protein	0.0025	0.0016	0.0016
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0021	0.001	0.2122
Loa Loa (eye worm)	pigment dispersing factor receptor c	0.0053	0.0053	0.0053
Loa Loa (eye worm)	hypothetical protein	0.7393	1	1
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0021	0.001	0.2122
Brugia malayi	Latrophilin receptor protein 2	0.0017	0.0004	0.0004
Leishmania major	target of rapamycin kinase (TOR) kinase 3	0.0021	0.001	0.3808
Plasmodium vivax	isocitrate dehydrogenase [NADP], mitochondrial, putative	0.0018	0.0006	0.2503
Echinococcus multilocularis	sterol regulatory element binding protein	0.0045	0.0042	0.004
Echinococcus multilocularis	phosphatidylinositol 3 and 4 kinase	0.0021	0.001	0.0007
Schistosoma mansoni	ataxia telangiectasia mutated (atm)-related	0.0021	0.001	0.0006
Mycobacterium ulcerans	acyl-CoA synthetase	0.0025	0.0016	1
Mycobacterium ulcerans	long-chain fatty-acid CoA ligase	0.0025	0.0016	1
Toxoplasma gondii	histone lysine methyltransferase SET1	0.0121	0.0145	1
Loa Loa (eye worm)	phosphatidylinositol 3	0.0021	0.001	0.001
Echinococcus granulosus	expressed conserved protein	0.0099	0.0115	0.0112
Mycobacterium ulcerans	long-chain-fatty-acid--CoA ligase	0.0025	0.0016	1

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL2229538

Bibliographic References

No literature references available for this target.

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Detailed information for compound 1809965